11 completed, 4 recruiting, 3 not yet recruiting, 3 withdrawn. 13 Not applicable, 2 Early Phase 1, 2 Phase 1, 2 Phase 4, 1 Phase 3.
Follow Tibial Plateau Fractures: new trials by email Literature Review of Tibial Plateau Fractures trials Research Report on Tibial Plateau Fractures
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Enhancing Wound Perfusion in High-Risk Lower Extremity Orthopaedic Surgery: A Study on Nitropaste Using Intraoperative SPY Imaging. Nitroglycerin Ointment 2% - Achilles Tendon Repairs/Reconstructions, Pilon Fracture of Tibia | Phase 1 | Not yet recruiting | Johns Hopkins University | 15 | 2026-11-01 | 2026-03-31 |
| Comparison of Functional Outcome Between Locking Plate Technique Versus Hybrid Ilizarov Technique in Patients With Schatzker Type V and VI Tibial Plateau Fractures Hybrid Ilizarov Fixation, Locking Plate Fixation - Tibial Plateau Fracture | Not applicable | Recruiting | Prof. Sajjad Hussain Goraya | 78 | 2026-08-16 | 2026-08-19 |
| Blood Flow Restriction Therapy Improves Tibial Plateau Fracture Recovery Blood Flow Restriction Cuff, Physical Therapy - Tibial Plateau Fractures | Not applicable | Withdrawn | Medical College of Wisconsin | 2025-12-01 | 2025-11-10 | |
| Saphenous Nerve Block After Tibial Plateau ORIF Saphenous Nerve Block with Ropivacaine Treatment, Saphenous Nerve Block with Saline Control - Tibial Plateau Fracture, Pain, Postoperative | Not applicable | Withdrawn | Stanford University | 2025-05-01 | 2026-07-01 | |
| Posterior Column Fractures of Tibial Plateau Open reduction and internal fixation - Tibial Plateau Fractures | Not yet recruiting | Assiut University | 32 | 2025-05-01 | 2025-04-17 | |
| Clinical Efficacy of Open Reduction and Suture Bridge Fixation for PCL Tibial Avulsion Fractures Clinical Efficacy of Open Reduction and Anchor Suture Bridge Fixation - Tibial Plateau Fracture | Not applicable | Completed | Second Affiliated Hospital of Soochow University | 17 | 2025-03-15 | 2025-04-09 |
| EFFECT OF EARLY WEIGHT BEARING AND ACTIVE KNEE EXERCISES IN TREATMENT OF TIBIAL PLATEAU FRACTURES Early active exercises will be applied from the first day by the participation of the patient with the assistance of the physiotherapist - Tibial Plateau Fractures | Not applicable | Enrolling by invitation | Cairo University | 28 | 2024-11-01 | 2025-11-26 |
| Genicular Nerve Block After Open Reduction Internal Fixation of Tibial Plateau Bupivacain - Tibial Plateau Fractures | Phase 1 | Recruiting | University of Chicago | 38 | 2024-11-01 | 2026-02-05 |
| Local Anesthetic for Plateau Fractures Bupivacaine injection, Saline - Tibial Plateau Fractures | Phase 4 | Not yet recruiting | University of Washington | 100 | 2024-08-01 | 2024-06-26 |
| Efficacy of the Use of 3D Printing Models in the Treatment of Tibial Plateau Fractures: a Randomized Clinical Trial Open reduction and internal fixation, Standard osteosynthesis planning, 3-D model osteosynthesis planning - Tibial Plateau Fracture | Not applicable | Completed | Pedro-José Torrijos-Garrido | 35 | 2022-10-01 | 2026-09-25 |
| Duloxetine Tibial Plateau Duloxetine, Placebo, Standard of care (SOC) for tibial plateau surgery - Tibial Plateau Fracture, Pain, Postoperative | Phase 4 | Withdrawn | Boston Medical Center | 2022-10-01 | 2022-11-21 | |
| Immediate Versus Late Weight Bearing After Tibial Plateau Fractures Internal Fixation Weight bearing as tolerated, Pragmatic Exercise protocol - Fracture of Tibia Proximal Plateau | Not applicable | Completed | Assiut University | 56 | 2022-09-01 | 2024-08-20 |
| Gene Expression in Lower Extremity Acute Traumatic Compartment Syndrome Acute injury without compartment syndrome, Acute injury with compartment syndrome, Exertional compartment syndrome - Tibial Shaft Fracture, Tibial Plateau Fracture | Not applicable | Enrolling by invitation | University of Utah | 80 | 2022-06-10 | 2026-04-29 |
| 3D Virtual Planning for Tibial Plateau Fractures 3D virtual planning software - Tibial Plateau Fracture | Not applicable | Unknown | Radboud University Medical Center | 70 | 2022-06-01 | 2022-05-31 |
| TPF Machine Learning Algorithms Tibial Plateau Fracture | Terminated | Universitaire Ziekenhuizen KU Leuven | 70 | 2020-10-05 | 2025-07-29 | |
| Knee Osteoarthritis in the Region of Norrbotten Osteoarthritis, Knee Injuries | Recruiting | Umeå University | 500 | 2020-09-01 | 2024-06-18 | |
| Role of Multimodal Analgesia in Decreasing Perioperative Pain in Tibial Plateau Fractures Saline injection, Multimodal injections - Tibial Plateau Fractures | Early Phase 1 | Active not recruiting | University of Utah | 150 | 2019-03-25 | 2026-04-29 |
| Early Advanced Weight Bearing for Peri-articular Knee and Pilon Injuries AlterG anti-gravity treadmill - Distal Femur Fracture, Tibial Plateau Fracture | Not applicable | Completed | Major Extremity Trauma Research Consortium | 81 | 2019-02-25 | 2023-12-22 |
| The Research About Acute Compartment Syndrome fasciotomy - Acute Compartment Syndrome | Recruiting | Hebei Medical University Third Hospital | 80 | 2019-01-01 | 2021-08-04 | |
| Predictors of Fracture-Dislocation in Schatzker IV Tibial Plateau Fractures: A Reproducible, Quantitative MRI-Based Injury-Pattern Analysis Is it dislocation? - Tibial Plateau Fracture | Completed | Second Affiliated Hospital of Soochow University | 77 | 2019-01-01 | 2026-03-19 |
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Tibial Fractures (3) · Pain, Postoperative (2) · Agnosia (1) · Ankle Fractures (1) · Femoral Fractures, Distal (1) · Fractures, Bone (1) · Intra-Articular Fractures (1) · Knee Injuries (1) · Osteoarthritis (1) · Osteoarthritis, Knee (1) · Patient Satisfaction (1) · Surgical Wound Dehiscence (1) · Wound Infection (1)
Knee Fractures (28) · Leg Injuries (28) · Wounds and Injuries (28) · Fractures, Bone (27) · Knee Injuries (27) · Tibial Fractures (25) · Pathological Conditions, Signs and Symptoms (4) · Neurologic Manifestations (3) · Pathologic Processes (3) · Postoperative Complications (3) · Signs and Symptoms (3) · Pain (2) · Ankle Injuries (1) · Arthritis (1) · Behavior (1)
Bupivacaine (3) · Fracture Fixation, Internal (2) · Open Fracture Reduction (2) · Sodium Chloride (2) · Clonidine (1) · Cryotherapy (1) · Duloxetine Hydrochloride (1) · Epinephrine (1) · Fasciotomy (1) · Ketorolac (1) · Ketorolac Tromethamine (1) · Morphine (1) · Negative-Pressure Wound Therapy (1) · Open Abdomen Techniques (1) · Physical Therapy Modalities (1)
University of Utah (4) · Assiut University (2) · Second Affiliated Hospital of Soochow University (2) · Boston Medical Center (1) · Cairo University (1) · Hebei Medical University Third Hospital (1) · Johns Hopkins University (1) · Major Extremity Trauma Research Consortium (1) · Medical College of Wisconsin (1) · National Trauma Center (1) · Pedro-José Torrijos-Garrido (1) · Poitiers University Hospital (1) · Prof. Sajjad Hussain Goraya (1) · Radboud University Medical Center (1) · Stanford University (1)
United States (11) · China (4) · Egypt (3) · Australia (2) · Netherlands (2) · Belgium (1) · Canada (1) · France (1) · Martinique (1) · Norway (1) · Pakistan (1) · Spain (1) · Sweden (1)
Justin Haller, MD (2) · Ali F Abdelrahem, lecturer (1) · Aly M Mohamed, Prof (1) · Anthony Christiano, MD (1) · Babar Shafi, MD, MSPT (1) · Daniel Stinner, MD (1) · Elizabeth Nolte, MD (1) · Erik Kubiak (1) · Harm Hoekstra, Prof. MD (1) · Henry T Shu, MD (1) · Hou Zhiyong, Doctor (1) · Ian Harris, MD (1) · Jean-Michel Brismee, Professor (1) · Jesse A Shantz, MD, MBA (1) · Job Doornberg, Professor (1)
PMID 31481365, PMID 33736638, PMID 36715712, PMID 40426131, PMID 42129866