7 completed, 2 terminated, 1 recruiting, 1 unknown. 12 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 12 | Completed 7, Terminated 2, Recruiting 1, Unknown 1, Withdrawn 1 |
Follow Lacerations: new trials by email Literature Review of Lacerations trials Research Report on Lacerations
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Ocular Surface Health and Tear Film Stability With a Nasal Spray Dry Eye Treatment Varenicline 0.03Mg/Spray Nasal Soln - Dry Eye, Meibomian Gland Dysfunction | Phase 4 | Recruiting | University of California, Berkeley | 65 | 2026-03-06 | 2026-05-27 |
| Effect of Topical Botulinum Toxin Eyedrop on Palpebral Fissure Botulinum toxin - Tears; Excess, Eyelid Spasm | Phase 4 | Terminated | University of Miami | 2 | 2022-11-29 | 2024-12-05 |
| Pain Experience Using Lidocaine Adrenaline Tetracaine (LAT) Gel Versus Lidocaine Infiltration for Laceration Repair in Adults Lidocaine-Adrenaline-Tetracaine (LAT) Gel, Lidocaine infiltration - Lacerations, Wound Repair | Phase 4 | Completed | Vrije Universiteit Brussel | 70 | 2021-04-01 | 2026-03-18 |
| Prospective Evaluation of Topical Analgesia for Laceration Repair in the Emergency Department Lidocaine-Prilocaine Cream 2.5-2.5%, Lidocaine 1% Epinephrine 0.005mg/mL solution - Pain, Acute, Laceration | Phase 4 | Completed | Centre Hospitalier le Mans | 132 | 2017-12-01 | 2022-03-10 |
| Comparison of Two Application Techniques for LET Gel LET Lidocaine (4%), Epinephrine (0.1%), and Tetracaine (0.5%) topical gel - Lacerations, Pain, Procedural | Phase 4 | Completed | Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center | 48 | 2017-05-22 | 2021-02-18 |
| Effectiveness of Nitrous Oxide in the ED Nitrous Oxide, Oxygen - Lacerations, Abscess | Phase 4 | Withdrawn | Christiana Care Health Services | 2016-03-01 | 2016-07-11 | |
| Intranasal Dexmedetomidine vs Intranasal Midazolam as Anxiolysis Prior to Pediatric Laceration Repair Dexmedetomidine, Midazolam - Laceration, Anxiety | Phase 4 | Completed | University of Pittsburgh | 40 | 2014-06-01 | 2024-11-14 |
| Prophylactic Antibiotic Treatment for Hand Lacerations Involving Flexor and/or Extensor Tendon Antibiotic-Cefamezin - Hand Laceration, Tendon Involved | Phase 4 | Completed | HaEmek Medical Center, Israel | 24 | 2013-08-01 | 2020-02-17 |
| Cosmetic Outcome Study of Lid Laceration Repair With Suture Versus Tissue Adhesive Tissue Adhesive skin closure, Absorbable suture skin closure, Non-absorbable suture skin closure - Eyelid Laceration | Phase 4 | Terminated | The University of Texas Health Science Center, Houston | 4 | 2013-08-01 | 2014-12-03 |
| A Randomized, Clinical Trial of Oral Midazolam Versus Oral Ketamine for Sedation During Laceration Repair. Midazolam - active comparator, Experimental Arm: Ketamine - Lacerations | Phase 4 | Unknown | Assaf-Harofeh Medical Center | 60 | 2013-08-01 | 2014-01-22 |
| Intranasal Midazolam for Treatment of Anxiety in Children Undergoing Suturing in the Pediatric Emergency Department Midazolam, Saline - Anxiety, Lacerations | Phase 4 | Completed | McGill University Health Centre/Research Institute of the McGill University Health Centre | 79 | 2010-01-01 | 2016-10-07 |
| Comparison of N2O Inhalation and Ketamine in Pediatric PSA N2O gas vs ketamine - Moderate Sedation, Laceration | Phase 4 | Completed | Seoul National University Hospital | 32 | 2009-01-01 | 2011-09-15 |
Anxiety Disorders (2) · Wounds and Injuries (2) · Abscess (1) · Acute Pain (1) · Agnosia (1) · Blepharospasm (1) · Dry Eye Syndromes (1) · Emergencies (1) · Meibomian Gland Dysfunction (1) · Pain, Procedural (1)
Wounds and Injuries (10) · Pathological Conditions, Signs and Symptoms (4) · Neurologic Manifestations (3) · Signs and Symptoms (3) · Eye Diseases (2) · Eyelid Diseases (2) · Mental Disorders (2) · Pain (2) · Pathologic Processes (2) · Disease Attributes (1) · Infections (1) · Inflammation (1) · Lacrimal Apparatus Diseases (1) · Nervous System Diseases (1) · Neurobehavioral Manifestations (1)
Midazolam (3) · Epinephrine (2) · Gels (2) · Botulinum Toxins (1) · Botulinum Toxins, Type A (1) · Cephalexin (1) · Cyanoacrylates (1) · Dexmedetomidine (1) · Ketamine (1) · Lidocaine (1) · Linear Energy Transfer (1) · Nitrous Oxide (1) · Oxygen (1) · Polypropylenes (1) · Sodium Chloride (1)
Assaf-Harofeh Medical Center (1) · Centre Hospitalier le Mans (1) · Christiana Care Health Services (1) · HaEmek Medical Center, Israel (1) · Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center (1) · McGill University Health Centre/Research Institute of the McGill University Health Centre (1) · Seoul National University Hospital (1) · The University of Texas Health Science Center, Houston (1) · University of California, Berkeley (1) · University of Miami (1) · University of Pittsburgh (1) · Vrije Universiteit Brussel (1)
United States (5) · Belgium (1) · France (1) · Israel (1) · South Korea (1)
Brian Levine, MD (1) · Desiree Neville, MD (1) · Jin Hee Lee, Professor (1) · Judianne Kellaway, MD (1) · Julien Fonsegrive, MD (1) · Kelly D Young, MD (1) · Wendy Lee, MD (1)
PMID 15572968, PMID 22694845, PMID 23187987, PMID 35100752
UL1TR000005 (1)