4 completed, 1 recruiting, 1 terminated. 2 Not applicable, 2 Phase 4, 1 Phase 1, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 2 | Completed 1, Terminated 1 |
| Phase 4 | 2 | Completed 2 |
| Phase 1 | 1 | Recruiting 1 |
| Phase 2 | 1 | Completed 1 |
Follow Linear Energy Transfer: new trials by email Literature Review of Linear Energy Transfer trials Research Report on Linear Energy Transfer
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Primary Anterior Cruciate Ligament Repair With and Without Lateral Extraarticular Tenodesis Primary anterior cruciate ligament repair, Primary anterior cruciate ligament repair and lateral extraarticular tenodesis (LET) with iliotibial band - Anterior Cruciate Ligament Tear | Not applicable | Completed | Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization | 38 | 2020-02-01 | 2023-08-31 |
| Comparison of 2 Application Techniques for LET Gel Used Prior to Simple Laceration Repair LET (lidocaine 4%; epinephrine 0.1%; tetracaine 0.5%) gel (1 application), LET (lidocaine 4%; epinephrine 0.1%; tetracaine 0.5%) gel (3 applications) - LET, Laceration of Skin | Phase 4 | Completed | Children's Hospital of Orange County | 48 | 2019-06-19 | 2020-09-02 |
| LET Optimized IMPT in Treating Pediatric Patients With Ependymoma Linear Energy Transfer-Optimized Intensity Modulated Proton Therapy, Quality-of-Life Assessment, Questionnaire Administration - Anaplastic Ependymoma, Ependymoma | Phase 1 | Recruiting | M.D. Anderson Cancer Center | 48 | 2019-04-01 | 2026-05-20 |
| Linear Energy Transfer (LET)-Optimized Intensity Modulated Proton Therapy (IMPT) as a Component of Definitive Chemoradiation for Newly Diagnosed Squamous Cell Carcinoma of the Anal Canal: a Feasibility Trial Cisplatin, Fluorouracil, Linear Energy Transfer-Optimized Intensity Modulated Proton Therapy - Anal Canal Squamous Cell Carcinoma, Stage I Anal Cancer AJCC v8 | Phase 2 | Completed | M.D. Anderson Cancer Center | 8 | 2018-11-08 | 2023-06-29 |
| Comparison of Two Application Techniques for LET Gel LET Lidocaine (4%), Epinephrine (0.1%), and Tetracaine (0.5%) topical gel - Lacerations, Pain, Procedural | Phase 4 | Completed | Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center | 48 | 2017-05-22 | 2021-02-18 |
| Radiation Therapy, Paclitaxel, and Carboplatin in Treating Patients With Uterine Cancer paclitaxel, carboplatin, external beam radiation therapy - Stage IA Uterine Sarcoma, Stage IB Uterine Sarcoma | Not applicable | Terminated | Albert Einstein College of Medicine | 14 | 2011-07-08 | 2023-08-21 |
Anterior Cruciate Ligament Injuries (1) · Anus Neoplasms (1) · Ependymoma (1) · Lacerations (1) · Pain, Procedural (1)
M.D. Anderson Cancer Center (2) · Albert Einstein College of Medicine (1) · Children's Hospital of Orange County (1) · Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center (1) · Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization (1)
United States (5) · Turkey (Türkiye) (1)
David R Grosshans (1) · Dennis Yi-Shin Kuo (1) · Emma B Holliday (1) · Joshua Siembieda (1) · Kelly D Young, MD (1) · Merieme Klobocista (1) · Yasin Guler, Md (1)
PMID 11665744, PMID 21331205, PMID 26542201, PMID 27047983, PMID 27324969, PMID 27894180, PMID 29373290, PMID 30298414, PMID 33532213, PMID 35100752
P30CA013330 (1), P30CA016672 (1), U19CA021239 (1)