8374 completed, 2324 unknown, 1357 recruiting, 848 terminated. 5217 Not applicable, 2146 Phase 2, 1574 Phase 3, 1260 Phase 4, 1217 Phase 1.
Follow Eye Diseases: new trials by email Literature Review of Eye Diseases trials Research Report on Eye Diseases
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| The Effect of Lumify™ on Ocular Redness, Intraocular Pressure, and Eyelid Position in Glaucoma Patients brimonidine tartrate ophthalmic solution 0.025%, sterile balanced saline solution - Glaucoma, Glaucoma, Open-Angle | Phase 4 | Not yet recruiting | Tulane University | 60 | 2027-11-01 | 2026-10-13 |
| A Phase 2 Study of RCI001 Ophthalmic Solution in Participants With Dry Eye Disease RCI001 Ophthalmic Solution, Placebo Ophthalmic Solution - Dry Eye | Phase 2 | Not yet recruiting | Rudacure | 200 | 2027-09-01 | 2026-06-04 |
| Know Your Pressures NYC Virtual Automated Navigator Intervention with Health Education, Usual Care - Glaucoma, Hypertension | Not applicable | Not yet recruiting | Columbia University | 7085 | 2027-07-01 | 2026-08-25 |
| Open-Label Extension Study of MHB018A in Patients With Thyroid Eye Disease MHB018A injection - Thyroid Eye Disease (TED) | Phase 3 | Not yet recruiting | Minghui Pharmaceutical (Hangzhou) Ltd | 219 | 2027-07-01 | 2026-06-04 |
| Comparative Efficacy of Saccadic and Biofeedback Training in Homonymous Hemianopia Biofeedback Fixation Training, Saccadic Reading Training - Hemianopia, Homonymous | Not applicable | Suspended | University of Alabama at Birmingham | 20 | 2027-06-01 | 2026-09-25 |
| Remapping Text in Sentence and Word Tasks to Aid Reading With Central Vision Loss Personalised Remapping Training, RSVP personalized remappi, Reading text in the wild with remapping - Macular Degeneration, Central Visual Impairment | Not applicable | Not yet recruiting | University of Minnesota | 100 | 2027-06-01 | 2026-07-07 |
| Safety and Efficacy of Intracameral Zimoxin for Prevention of Endophthalmitis After Cataract Surgery Moxifloxacin, Placebo - Endophthalmitis | Phase 2 / Phase 3 | Not yet recruiting | Jason Ahee, M.D. | 60000 | 2027-06-01 | 2026-09-15 |
| Nicotinamide for Retinal Protection in Primary Open-Angle Glaucoma (NADIR Trial) Nicotinamide, Standard Glaucoma Therapy - Glaucoma, Open-angle, Primary Open Angle Glaucoma (POAG) | Phase 2 | Not yet recruiting | University of Chicago | 96 | 2027-06-01 | 2026-10-13 |
| Body Image, Identity Development, and Social Media Use Among Youth With Visual Impairment: A Single Case Intervention Study Body image intervention - Visual Impairment, Cerebral Visual Impairment | Not applicable | Not yet recruiting | Universitaire Ziekenhuizen KU Leuven | 15 | 2027-05-01 | 2026-08-03 |
| The Emmetropization Via Accommodation (EVA) - II Study Experimental treatment arm - Hyperopia, Farsightedness | Not applicable | Not yet recruiting | Ohio State University | 52 | 2027-04-01 | 2026-09-24 |
| Eye Health Intervention Study in Upper Manhattan Intervention, Usual Care - Glaucoma, Suspect, Diabetic Retinopathy | Not applicable | Withdrawn | Columbia University | 2027-04-01 | 2026-05-29 | |
| A Basket Clinical Study to Assess Glycerol Tributyrate in Patients With Mitochondrial Encephalopathy, Lactic Acidosis, Stroke-like Episodes (MELAS) or Leber's Hereditary Optic Neuropathy-Plus (LHON-Plus) Glycerol Tributyrate - MELAS Syndrome, Lebers Hereditory Optic Neuropathy With Extra Ocular Symptoms (LHON-Plus) | Phase 1 / Phase 2 | Not yet recruiting | George Washington University | 24 | 2027-03-01 | 2026-10-05 |
| Locoregional Administration of TIL and Lymphodepletion in Patients With Melanoma and Liver Metastases Autologous Tumor Infiltrating Lymphocytes, Melphalan, Interleukin-2 - Uveal Melanoma, Metastatic Cutaneous Melanoma | Phase 1 | Not yet recruiting | Vastra Gotaland Region | 6 | 2027-01-31 | 2026-09-09 |
| Digital Health Technologies for Progressive Supranuclear Palsy and Dementia With Lewy Bodies Progressive Supranuclear Palsy(PSP), Dementia With Lewy Bodies (DLB) | Not yet recruiting | BioSensics | 60 | 2027-01-15 | 2026-10-13 | |
| Non-invasive Ultrasound Retinal Stimulation for Vision Restoration Non-invasive ultrasound retinal stimulation Device - Age-Related Macular Degeneration, Retinitis Pigmentosa | Not applicable | Not yet recruiting | University of Southern California | 5 | 2027-01-10 | 2026-01-08 |
| MIND-AMD Study: a Multidisciplinary Investigation of Neuroretinal Damage in Age-related Macular Degeneration. Age-Related (Dry) Macular Degeneration, Age-Related Macular Degeneration (AMD) | Not yet recruiting | IRCCS San Raffaele | 160 | 2027-01-02 | 2026-09-29 | |
| Promoting Psychophysical Well-being in Children and Adolescents With Visual Impairment Adapted Physical Activity Programme - Visual Impairment, Cerebral Visual Impairment | Not applicable | Not yet recruiting | Università degli Studi di Trento | 20 | 2027-01-01 | 2026-07-14 |
| Study of Platelet Rich Plasma Drops to Moderate Clinically Significant Dry Eye Platelet Poor Plasma Tear Drops, Platelet Rich Plasma Tear Drops - Dry Eye Syndromes | Not applicable | Withdrawn | University of Rochester | 2027-01-01 | 2026-07-16 | |
| Outcomes of Stentless Dacryocystorhinostomy in Primary Acquired Nasolacrimal Duct Obstruction. Stentless Endoscopic Dacryocystorhinostomy - Nasolacrimal Duct Obstruction, Epiphora | Not applicable | Not yet recruiting | Assiut University | 40 | 2027-01-01 | 2026-09-30 |
| Locoregional or Systemic Administration of Autologous Tumor Infiltrating Lymphocytes in Patients With Metastatic Melanoma Autologous Tumor Infiltrating Lymphocytes (TIL), Melphalan, Interleukin-2 - Metastatic Uveal Melanoma, Metastatic Cutaneous Melanoma | Phase 1 | Not yet recruiting | Vastra Gotaland Region | 18 | 2027-01-01 | 2026-09-09 |
Showing 20 of 14594. Sign in to see all of them.
Cataract (1407) · Glaucoma (1359) · Dry Eye Syndromes (1347) · Macular Degeneration (1170) · Myopia (1086) · Glaucoma, Open-Angle (917) · Diabetic Retinopathy (683) · Ocular Hypertension (654) · Refractive Errors (420) · Macular Edema (418) · Astigmatism (402) · Vision Disorders (349) · Presbyopia (333) · Retinal Diseases (333)
Retinal Diseases (3269) · Pathological Conditions, Signs and Symptoms (2311) · Nervous System Diseases (2244) · Retinal Degeneration (1881) · Lacrimal Apparatus Diseases (1659) · Signs and Symptoms (1565) · Refractive Errors (1516) · Ocular Hypertension (1497) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (1458) · Lens Diseases (1448) · Neurologic Manifestations (1401) · Cardiovascular Diseases (1391) · Immune System Diseases (1388) · Vascular Diseases (1363)
Ranibizumab (384) · aflibercept (245) · Ophthalmic Solutions (218) · Bevacizumab (183) · Latanoprost (169) · Cataract Extraction (160) · Timolol (131) · Dexamethasone (129) · Travoprost (105) · salicylhydroxamic acid (98) · Calcium Dobesilate (96) · Brimonidine Tartrate (94) · Phacoemulsification (92) · Tomography, Optical Coherence (89) · Lubricant Eye Drops (87)
Alcon Research (536) · National Eye Institute (NEI) (238) · Allergan (202) · Bausch & Lomb Incorporated (161) · CooperVision, Inc. (150) · Sun Yat-sen University (146) · Assiut University (138) · Medical University of Vienna (135) · Novartis Pharmaceuticals (130) · Zhongshan Ophthalmic Center, Sun Yat-sen University (113) · Johnson & Johnson Vision Care, Inc. (88) · Johns Hopkins University (86) · Fondation Ophtalmologique Adolphe de Rothschild (85) · University of California, San Francisco (79) · National Taiwan University Hospital (74)
United States (5334) · China (1258) · France (904) · United Kingdom (776) · Canada (710) · Germany (703) · Italy (565) · Spain (541) · Austria (426) · Egypt (387) · South Korea (360) · Australia (346) · Israel (284) · Taiwan (281) · Turkey (Türkiye) (273)
Georgios Labiris, MD, PhD (26) · Gail Torkildsen, MD (21) · Emily Y Chew, M.D. (15)
PMID 36809645, PMID 37314061, PMID 35943114, PMID 40522203, PMID 36912740, PMID 37702300, PMID 10937547, PMID 20451898, PMID 30194931, PMID 22108357, PMID 32408387, PMID 32557558, PMID 36729473, PMID 26875007, PMID 32374423, PMID 32573764, PMID 34707360, PMID 36912792, PMID 37260074, PMID 40547876, PMID 12649304, PMID 12823990, PMID 24974815, PMID 25179431, PMID 30957581, PMID 32280196, PMID 33263359, PMID 36449262, PMID 9778415, PMID 12719068, PMID 14508260, PMID 17122118, PMID 22281388, PMID 23049090, PMID 25458728, PMID 26089210, PMID 27929721, PMID 28736340, PMID 32844399, PMID 34108929, PMID 34516656, PMID 34934034, PMID 37172782, PMID 37619861, PMID 39758130, PMID 39839752, PMID 10815152, PMID 11237914, PMID 11879137, PMID 12049574
2019 (38), 2014 (33), U10EY011751 (33), 2018 (31), 2023 (28), 2025 (26), 2009 (25), 2016 (25), 2015 (24), 2017 (22), 2008 (11), U01CA081457 (9), U10CA098543 (9), U10EY014231 (9), 2005 (8)