255 completed. 255 Phase 2, 53 Phase 1, 32 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 255 | Completed 255 |
| Phase 1 | 53 | Completed 53 |
| Phase 3 | 32 | Completed 32 |
Follow Ischemia: new trials by email Literature Review of Ischemia trials Research Report on Ischemia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Dexrazoxane to Protect Against Hemorrhagic STEMI Dexrazoxane, Normal Saline - Acute Myocardial Infarction (AMI) | Phase 2 | Completed | Rohan Dharmakumar | 50 | 2025-08-30 | 2026-05-26 |
| Early Intracoronary N-Acetylcysteine During Primary PCI in STEMI: A Pilot Randomized Trial of Reperfusion Injury Biomarkers and Functional Recovery Antipac - STEMI - ST Elevation Myocardial Infarction (MI), Primary PCI - STEMI | Phase 2 | Completed | dr. Ahmad Yasa, Sp.JP, Subsp.K.I.(K), M.Kes, FIHA, FasCC, FA | 110 | 2025-04-01 | 2026-10-02 |
| Efficacy of Varenicline Tartrate in Treating Frequent Premature Ventricular Contractions Varenicline Tartrate Tablets, Placebo - Premature Ventricular Contraction (PVC) | Phase 2 | Completed | Yihan Chen | 116 | 2025-02-17 | 2025-11-19 |
| TP03HN106 in Patients With Critical Limb Ischemia TP03HN106 - Critical Limb Ischemia | Phase 2 | Completed | Talengen Institute of Life Sciences, Shenzhen, P.R. China. | 15 | 2024-07-18 | 2026-09-30 |
| A Study of RTP-026 to Assess Safety, Tolerability and Efficacy in Patients With ST-Elevation Myocardial Infarction (STEMI) RTP-026, Placebo - ST Elevation Myocardial Infarction | Phase 2 | Completed | ResoTher Pharma | 66 | 2024-07-16 | 2026-09-24 |
| Oral Nicorandil for Prevention of No Reflow Phenomenon in Anterior STEMI Patients Undergoing PPCI Nicorandil 20mg - No Reflow Phenomenon, Anterior STEMI | Phase 1 / Phase 2 | Completed | Ain Shams University | 300 | 2024-03-10 | 2025-08-24 |
| Polyamine Treatment in Elderly Patients With Coronary Artery Disease Spermidine, Placebo - Ischemic Heart Disease, Myocardial Infarction | Phase 2 | Completed | University of Aarhus | 187 | 2024-01-01 | 2026-07-01 |
| Normal Saline Infusion for Stroke After Intravenous Thrombolysis 0.9% NaCl 2000ml, 0.9% NaCl 200-400ml - Brain Infarct | Phase 2 | Completed | Tianjin Medical University General Hospital | 241 | 2023-09-01 | 2025-03-12 |
| MLC1501 Study Assessing Efficacy in Post STrOke Subjects With mOtor Deficits Placebo, MLC1501 - Stroke, Stroke, Ischemic | Phase 2 | Completed | Moleac Pte Ltd. | 303 | 2023-07-21 | 2025-12-09 |
| Pulse Glucocorticoid Therapy in Patients With ST-Segment Elevation Myocardial Infarction Methylprednisolone, Isotonic saline - ST Elevation Myocardial Infarction, Inflammatory Response | Phase 2 | Completed | Thomas Engstrom | 530 | 2022-11-14 | 2026-03-27 |
| Study to Assess Efficacy and Safety of CDR132L in Patients With Reduced Left Ventricular Ejection Fraction After Myocardial Infarction CDR132L, Placebo to CDR132L - Myocardial Infarction, Acute, Heart Failure, Left Sided | Phase 2 | Completed | Cardior Pharmaceuticals GmbH | 294 | 2022-07-11 | 2026-08-26 |
| Adrenomedullin for CADASIL Adrenomedullin - Cadasil | Phase 2 | Completed | National Cerebral and Cardiovascular Center, Japan | 60 | 2022-01-06 | 2023-10-10 |
| XTR003 PET Radiotracer for the Detection of Viable Myocardium XTR003 - Ischemic Heart Disease (IHD) | Phase 2 | Completed | Sinotau Pharmaceutical Group | 51 | 2021-12-15 | 2023-06-02 |
| Comparison Between the Effects of High Doses Statin on Ventricular Remodeling in STEMI Patients Rosuvastatin 20 mg, Atorvastatin 40mg - ST-segment Elevation Myocardial Infarction | Phase 2 | Completed | Damanhour University | 80 | 2021-11-01 | 2024-08-01 |
| Impact of DApagliflozin on Cardiac Function Following Anterior Myocardial Infarction in Non-Diabetic Patients Dapagliflozin 10mg, Glucose Tab - Anterior MI | Phase 2 / Phase 3 | Completed | Omar Younis | 100 | 2021-10-01 | 2024-11-19 |
| Exploratory Study on the Safety, Tolerability, and Pharmacodynamics of IMB-1018972 in Subjects With Angina Due to Obstructive Coronary Artery Disease (IMPROVE-Ischemia) IMB-1018972, Placebo - Ischemia, Coronary Artery Disease | Phase 2 | Completed | Imbria Pharmaceuticals, Inc. | 58 | 2021-04-23 | 2024-04-23 |
| MiSaver® Stem Cell Treatment for Heart Attack (Acute Myocardial Infarction) MiSaver® - Myocardial Infarction | Phase 1 / Phase 2 | Completed | Honya Medical Inc | 11 | 2021-01-26 | 2024-03-29 |
| Efficacy and Safety of Tocotrienols in CADASIL HOV-12020 (Palm tocotrienols complex), Placebo - Cadasil | Phase 2 | Completed | Hovid Berhad | 50 | 2020-12-21 | 2026-02-02 |
| Study to Evaluate the Effect on Parameters of Systemic Inflammation and Disease Outcomes and Safety of RPH-104 in Subjects With Acute ST-elevation Myocardial Infarction RPH-104 80 mg, Placebo - Acute ST Segment Elevation Myocardial Infarction | Phase 2 | Completed | R-Pharm Overseas, Inc. | 102 | 2020-12-07 | 2024-06-24 |
| Efficacy and Safety of Mesenchymal Stem Cell Clusters in Patients with Critical Limb Ischemia Clusters of adipose-derived mesenchymal stem cells (Dose: 1 x 10^7 cells/1 mL/vial), Clusters of adipose-derived mesenchymal stem cells (Dose: 1 x 10^8 cells/1 mL/vial) - Critical Limb Ischemia | Phase 1 / Phase 2 | Completed | S.Biomedics Co., Ltd. | 20 | 2020-11-04 | 2024-08-30 |
Showing 20 of 255. Sign in to see all of them.
Myocardial Infarction (98) · ST Elevation Myocardial Infarction (42) · Chronic Limb-Threatening Ischemia (39) · Stroke (33) · Coronary Artery Disease (27) · Ischemic Stroke (17) · Cerebral Infarction (15) · Peripheral Vascular Diseases (15) · Myocardial Ischemia (14) · Acute Coronary Syndrome (13) · Heart Failure (13) · Peripheral Arterial Disease (12) · Angina, Unstable (11) · Cardiovascular Diseases (10)
Pathological Conditions, Signs and Symptoms (255) · Pathologic Processes (252) · Cardiovascular Diseases (234) · Vascular Diseases (234) · Necrosis (177) · Infarction (172) · Heart Diseases (149) · Myocardial Ischemia (141) · Arteriosclerosis (70) · Arterial Occlusive Diseases (63) · Nervous System Diseases (48) · Myocardial Infarction (46) · Brain Diseases (45) · Central Nervous System Diseases (45)
Clopidogrel (10) · Aspirin (9) · Sodium Chloride (8) · Saline Solution (6) · Percutaneous Coronary Intervention (5) · Ticagrelor (5) · Atorvastatin (4) · Tenecteplase (4) · Eptifibatide (3) · Injections (3) · Plasmalyte A (3) · AC133 Antigen (2) · Capsules (2) · Cell- and Tissue-Based Therapy (2) · Doxycycline (2)
University of Alberta (5) · Andalusian Initiative for Advanced Therapies - Fundación Pública Andaluza Progreso y Salud (4) · National Heart, Lung, and Blood Institute (NHLBI) (4) · AnGes USA, Inc. (3) · Medical University of Vienna (3) · Oslo University Hospital (3) · Region Skane (3) · Stempeutics Research Pvt Ltd (3) · University Medical Center Groningen (3) · AstraZeneca (2) · Bayer (2) · Flanders Medical Research Program (2) · Fondazione IRCCS Policlinico San Matteo di Pavia (2) · Germans Trias i Pujol Hospital (2) · Hospices Civils de Lyon (2)
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Ali Eskandari, MD (2) · Antonio Chacon, MD, PhD (2) · Diego Martinez, MD, PhD (2) · Hossein Baharvand, PhD (2) · Hossein Vakili, M.D. (2) · Inmaculada Herrera, MD, PhD (2) · Marc Bosiers, MD (2) · Maryam Keshtkar-Jahromi, M.D.; M.P.H. (2) · Richard Powell, MD (2) · Seyed Mostafa Razavi, MD (2) · Sharareh Gholamin, MD (2) · A A Voors, MD,PhD (1) · A.Michael Lincoff, MD (1) · Abhiram Prasad, M.D. (1)
PMID 22163120, PMID 35802393, PMID 21079055, PMID 22212857, PMID 22795280, PMID 12460865, PMID 15480537, PMID 15498829, PMID 16413875, PMID 16750696, PMID 16949482, PMID 16990383, PMID 17172279, PMID 17320744, PMID 17698683, PMID 18460663, PMID 18535785, PMID 18559698, PMID 18559703, PMID 18599344, PMID 18984888, PMID 19064521, PMID 19116389, PMID 19131132, PMID 19232907, PMID 19237716, PMID 19359665, PMID 19451353, PMID 19491213, PMID 19491386, PMID 19608137, PMID 19608488, PMID 19640572, PMID 19679246, PMID 19711453, PMID 19834012, PMID 19923168, PMID 19940774, PMID 19958860, PMID 19996767, PMID 20078390, PMID 20102300, PMID 20124733, PMID 20189026, PMID 20194878, PMID 20529449, PMID 20542780, PMID 20620737, PMID 20675660, PMID 20705929
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