16 completed, 6 terminated, 5 unknown, 1 not yet recruiting. 14 Phase 2, 8 Phase 3, 5 Phase 4, 3 Phase 1.
Follow Eptifibatide: new trials by email Literature Review of Eptifibatide trials Research Report on Eptifibatide
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Eptifibatide for Extended Window Ischemic Stroke After Thrombolysis Eptifibatide (Integrilin), Standard Medical Therapy - Acute Ischemic Stroke | Phase 3 | Not yet recruiting | Xinqiao Hospital of Chongqing | 786 | 2026-03-01 | 2026-01-16 |
| Platelet Function in Patients With Ischemic Stroke Treated With Anti-thrombotic or Thrombolytic Thrombolytic Agent - Acute Ischemic Stroke | Phase 1 / Phase 2 | Unknown | Baylor College of Medicine | 30 | 2022-02-18 | 2022-06-10 |
| Multi-arm Optimization of Stroke Thrombolysis Argatroban, Eptifibatide, Placebo - Acute Ischemic Stroke | Phase 3 | Completed | Washington University School of Medicine | 514 | 2019-10-15 | 2025-02-07 |
| Eptifibatide in Endovascular Treatment of Acute Ischemic Stroke (EPOCH) Eptifibatide Injection - Acute Ischemic Stroke | Phase 3 | Unknown | Ministry of Science and Technology of the People´s Republic of China | 220 | 2019-04-06 | 2019-06-18 |
| Pharmacologic Treatment of Myocardial Ischemia Detected by Intracoronary ECG Intracoronary bolus of adenosine (adenocor), Integrilin (eptifibatide) or nitroglyzerin (nitronal) - Coronary Ischemia | Unknown | Alexandrovska University Hospital | 60 | 2018-01-03 | 2017-12-26 | |
| Crushed Ticagrelor Versus Eptifibatide Bolus + Clopidogrel Ticagrelor, Eptifibatide, Clopidogrel - Acute Coronary Syndrome, Angina, Unstable | Phase 2 | Completed | University of Alabama at Birmingham | 100 | 2016-11-01 | 2020-05-04 |
| Ticagrelor and Eptifibatide Bolus-Only Versus Ticagrelor and Eptifibatide Bolus Plus Abbreviated Infusion Ticagrelor, Eptifibatide - Acute Coronary Syndrome | Phase 2 | Completed | University of Alabama at Birmingham | 70 | 2014-02-01 | 2017-02-28 |
| Study of the Combination Therapy of Rt-PA and Eptifibatide to Treat Acute Ischemic Stroke (CLEAR-FDR) Eptifibatide - Stroke, Brain Infarction | Phase 2 | Completed | Arthur Pancioli | 27 | 2013-09-01 | 2016-01-21 |
| Integrilin and Ilomedin in Combination in Comparison to Standard Treatment in Severe Pneumonia Patients With Severe Sepsis Ilomedin and Integrilin, low molecular weight heparin. - Pneumonia | Phase 2 | Terminated | Thrombologic ApS | 5 | 2012-06-01 | 2016-04-22 |
| Shortened Aggrastat® Versus Integrilin in Percutaneous Coronary Intervention Short Tirofiban, Eptifibatide, Long Tirofiban - Myocardial Infarction, Acute Coronary Syndromes | Phase 2 | Completed | Medicure | 535 | 2012-04-01 | 2021-05-13 |
| Effect of Otamixaban Versus Unfractionated Heparin + Eptifibatide in Patients With Unstable Angina/Non ST Elevation Myocardial Infarction Undergoing Early Invasive Strategy Otamixaban, Placebo (for Otamixaban), UFH - Acute Coronary Syndrome | Phase 3 | Completed | Sanofi | 13220 | 2010-04-01 | 2016-05-04 |
| Effectiveness of Intracoronary Injection of Eptifibatide in Primary Coronary Intervention in STEMI Patients Eptifibatide - Acute Myocardial Infarction | Phase 2 | Unknown | Assaf-Harofeh Medical Center | 50 | 2009-08-01 | 2009-07-24 |
| Study of the Combination Therapy of Rt-PA and Eptifibatide to Treat Acute Ischemic Stroke Eptifibatide, rt-PA - Ischemic Stroke, Stroke | Phase 2 | Completed | University of Cincinnati | 126 | 2009-07-01 | 2014-04-17 |
| A Safety Study of Eptifibatide in Patients With Sickle Cell Disease Eptifibatide, Placebo - Sickle Cell Disease | Phase 1 / Phase 2 | Terminated | University of North Carolina, Chapel Hill | 13 | 2009-01-01 | 2013-06-27 |
| INSTANT: INtegrilin Plus STenting to Avoid Myocardial Necrosis Trial eptifibatide, placebo - Cardiovascular Disease | Phase 3 | Completed | Fondazione Evidence per Attività e Ricerche Cardiovascolari ONLUS | 91 | 2007-11-01 | 2010-05-28 |
| A Safety/Efficacy Study of Intracoronary Integrilin to Improve Balloon Angioplasty Outcomes for the Treatment of Heart Attacks eptifibatide, normal saline - ST-Elevation Myocardial Infarction | Phase 2 | Terminated | Brigham and Women's Hospital | 31 | 2007-11-01 | 2012-08-27 |
| The INtegrilin Plus STenting to Avoid Myocardial Necrosis Trial (INSTANT) Eptifibatide - Coronary Artery Disease | Phase 4 | Terminated | University of Turin, Italy | 91 | 2007-10-01 | 2011-10-19 |
| Eptifibatide and ST Segment Resolution Following Primary PCI eptifibitide - Myocardial Infarction | Phase 3 | Terminated | Medstar Health Research Institute | 22 | 2007-08-01 | 2014-08-11 |
| Aspirin Resistance and Percutaneous Coronary Intervention (PCI) Intravenous Glycoprotein inhibitor + ASA, Clopidogrel, Antiplatelet Therapy (ASA, Clopidogrel) - Stable Angina | Phase 2 | Completed | Icahn School of Medicine at Mount Sinai | 36 | 2007-04-01 | 2018-02-14 |
| Efficacy Of Eptifibatide Compared To Abciximab In Primary Percutaneous Coronary Intervention (PCI) For Acute ST Elevation Myocardial Infarction (STEMI) Abciximab, Eptifibatide - Infarction, Myocardial | Phase 3 | Completed | GlaxoSmithKline | 429 | 2006-10-01 | 2012-11-27 |
Showing 20 of 28. Sign in to see all of them.
Ischemic Stroke (7) · Myocardial Infarction (6) · Acute Coronary Syndrome (5) · Coronary Artery Disease (4) · ST Elevation Myocardial Infarction (3) · Stroke (3) · Angina, Unstable (2) · Brain Infarction (2) · Cardiovascular Diseases (2) · Thrombosis (2) · Anemia, Sickle Cell (1) · Angina Pectoris (1) · Angina, Stable (1) · Blushing (1) · Coronary Disease (1)
Brigham and Women's Hospital (2) · Sanofi (2) · University of Alabama at Birmingham (2) · University of Cincinnati (2) · Alexandrovska University Hospital (1) · Arthur Pancioli (1) · Assaf-Harofeh Medical Center (1) · Baylor College of Medicine (1) · Cardiology Research UBC (1) · Fondazione Evidence per Attività e Ricerche Cardiovascolari ONLUS (1) · GlaxoSmithKline (1) · Icahn School of Medicine at Mount Sinai (1) · LifeBridge Health (1) · Medical University of Silesia (1) · Medicure (1)
United States (18) · Italy (4) · Bulgaria (3) · Canada (3) · France (3) · Germany (3) · Israel (3) · Poland (3) · Argentina (2) · Austria (2) · Brazil (2) · Chile (2) · China (2) · Colombia (2) · Croatia (2)
Massoud Leesar, MD (2) · Opeolu Adeoye, MD (2) · Annapoorna S Kini, MD MRCP (1) · Anthony Fung, MB,BS, FRCPC (1) · Arthur M Pancioli, MD (1) · Arthur Pancioli, MD (1) · C. Michael Gibson, M.D. (1) · Daniel I Simon, MD (1) · Daojun Hong, MD (1) · Eugene Braunwald, M.D. (1) · Kenneth I Ataga, MD (1) · Miroslaw Wilczynski, MD, PhD (1)
PMID 19232896, PMID 19264239, PMID 19332455, PMID 19463380, PMID 19706858, PMID 19717184, PMID 20670755, PMID 21300952, PMID 22373905, PMID 22607870, PMID 22645292, PMID 22995880, PMID 23392654, PMID 23416014, PMID 23537976, PMID 23887841, PMID 23973010, PMID 23995608, PMID 24016495, PMID 24093853, PMID 24562802, PMID 24607027, PMID 26243231, PMID 26957532, PMID 28052979, PMID 28089149, PMID 28611098, PMID 29895599, PMID 31766977, PMID 31976867, PMID 3201508, PMID 33296224, PMID 33297893, PMID 33427887, PMID 33430604, PMID 33518473, PMID 34329730, PMID 34838189, PMID 35105182, PMID 35130717, PMID 35224730, PMID 36711206, PMID 37256980, PMID 39231343, PMID 40123511, PMID 40824660, PMID 41071964
2009 (1), P50NS044283 (1), U01NS100699 (1)