1110 completed, 407 unknown, 193 recruiting, 135 terminated. 886 Not applicable, 230 Phase 2, 172 Phase 3, 145 Phase 4, 141 Phase 1.
Follow Peripheral Vascular Diseases: new trials by email Literature Review of Peripheral Vascular Diseases trials Research Report on Peripheral Vascular Diseases
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| FGF-1 for Intramuscular Injection for the Treatment of Peripheral Arterial Disease FGF-1, Placebo - Peripheral Arterial Disease, Stenosis | Phase 1 / Phase 2 | Not yet recruiting | Venturis Therapeutics, Inc. | 24 | 2028-10-15 | 2026-08-19 |
| Vitamin B6 on Exercise Pressor Reflex on Leg Ischemia-reperfusion Vitamin B6 25 MG, Vitamin B6 50 MG, Vitamin B6 100 MG - Ischemia Reperfusion Injury, Peripheral Artery Disease | Early Phase 1 | Not yet recruiting | Milton S. Hershey Medical Center | 30 | 2027-12-01 | 2026-03-17 |
| PAtient Similarity for Decision-Making in Prevention of Cardiovascular Toxicity (PACT): A Feasibility Study Clinical Decision Aid, Standard Care - Heart Failure, Coronary Artery Disease | Not yet recruiting | Medical College of Wisconsin | 60 | 2027-12-01 | 2026-11-03 | |
| Study to Image Inflammatory Activity of a Fluorescence Imaging Agent in Excised Human Artery Plaques Pegulicianine, Placebo - Carotid Artery Diseases, Peripheral Arterial Disease | Early Phase 1 | Not yet recruiting | Massachusetts General Hospital | 25 | 2027-06-01 | 2026-11-10 |
| Evaluation of Botulinum TOXin Type A in the Treatment of Buerger's Disease BOTOX INJECTION - Buerger Disease, Raynaud Syndrome | Phase 3 | Not yet recruiting | University Hospital, Toulouse | 8 | 2027-01-01 | 2026-07-23 |
| Daily Stretching to Improve Walking in Older Patients With Peripheral Artery Disease: The STRETCH PAD Study Therapeutic calf stretching, Sham calf stretching - Peripheral Artery Disease (PAD), Intermittent Claudication | Not applicable | Not yet recruiting | Penn State University | 300 | 2027-01-01 | 2026-11-05 |
| Drug-coated Balloons Versus Drug-eluting Stents for the Treatment of Femoropopliteal In-Stent Restenosis Drug-Coated Balloon-First Strategy, Eluvia Drug-Eluting Stent-First Strategy - Femoropopliteal In-Stent Restenosis (ISR) | Not yet recruiting | Chunshui He | 600 | 2027-01-01 | 2026-11-02 | |
| FRAME, External Support for Lower Limb Autologous Grafts FRAME - Peripheral Arterial Disease, Peripheral Artery Disease | Not applicable | Suspended | Vascular Graft Solutions Ltd. | 30 | 2026-12-31 | 2025-02-04 |
| Spectroscopic Assessment of Tissue Oxygenation Changes During Vascular Surgery Peripheral Arterial Disease, Chronic Limb-Threatening Ischemia | Not yet recruiting | Spectrocor | 30 | 2026-12-01 | 2026-08-26 | |
| DCB Outcomes After Non-Compliant Balloon Vessel Preparation With or Without Scoring in Patients With Femoropopliteal Arterial Disease Non-compliant Plain Balloon angioplasty (PBA), Non-compliant Scoring Balloon Angioplasty (SB) - Femoropopliteal Disease, Drug Coated Balloon | Not applicable | Not yet recruiting | Marc Sirvent | 142 | 2026-12-01 | 2026-10-07 |
| The NICE-PAD II Trial Nicotinamide Riboside (NR), Placebo - Peripheral Artery Disease (PAD) | Phase 3 | Not yet recruiting | Northwestern University | 250 | 2026-12-01 | 2026-08-24 |
| XPAD European Feasibility Study XPAD conduit - Peripheral Arterial Disease | Not applicable | Not yet recruiting | Xeltis | 15 | 2026-12-01 | 2026-07-21 |
| IV-X Medical Peripheral Intravascular Lithotripsy Study for PAD IV-X Medical IVL System - Peripheral Artery Disease (PAD) | Not applicable | Not yet recruiting | IVX Medical | 140 | 2026-12-01 | 2026-10-21 |
| Perioperative Limb Oxygenation Monitoring in Patients With CLTI Near-infrared spectroscopy (NIRS, Medtronic, INVOS) tissue oxygenation monitoring - Chronic Limb Threatening Ischemia, CLTI | Not applicable | Recruiting | Belarusian State Medical University | 120 | 2026-11-02 | 2026-11-12 |
| Hemodynamic Characteristics of Peripheral Arterial Disease Using Computational Fluid Dynamics Computational Fluid Dynamics Simulation - Peripheral Arterial Disease | Not yet recruiting | Fudan University | 14 | 2026-11-01 | 2026-10-06 | |
| Emerging Indications for Hyperbaric Oxygen Treatment Hyperbaric oxygen treatment (HBOT), 100% Oxygen - Post-COVID-19 Condition, Ulcerative Colitis | Phase 4 | Not yet recruiting | Jay C. Buckey Jr. | 100 | 2026-11-01 | 2026-09-09 |
| Clinical Value of CT Perfusion in Peripheral Artery Disease Peripheral Artery Disease (PAD), CT Perfusion | Not yet recruiting | Fudan University | 200 | 2026-11-01 | 2026-09-14 | |
| A Bioequivalence and Safety Study of AJU-B718 and B718R in Healthy Adult Volunteers Under Fasting Conditions Test Drug, Reference Drug - Peripheral Arterial Disease | Phase 1 | Not yet recruiting | AJU Pharm Co., Ltd. | 40 | 2026-11-01 | 2026-10-28 |
| REducing Systemic Inflammation With LOw-dose Colchicine to ImproVE Cardiovascular Calcification in Chronic Kidney Disease: A Pilot Randomized Open-Label Trial Low-dose Colchicine at 0.5mg daily, Usual Care - Chronic Kidney Disease Mineral and Bone Disorder, Cognitive Function | Phase 2 | Not yet recruiting | University of Texas Southwestern Medical Center | 60 | 2026-10-30 | 2026-11-04 |
| A Study of LIQ861 (Inhaled Treprostinil) in Adults With Systemic Sclerosis Who Have Symptomatic Raynaud's Phenomenon Attacks LIQ861 (treprostinil) inhalation powder - Dose Titration Arm, LIQ861 (treprostinil) inhalation powder - fixed dose arm - Raynaud's Phenomenon Secondary to Systemic Sclerosis | Phase 2 | Not yet recruiting | Liquidia Technologies, Inc. | 75 | 2026-10-26 | 2026-08-07 |
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Peripheral Arterial Disease (1362) · Chronic Limb-Threatening Ischemia (354) · Intermittent Claudication (307) · Atherosclerosis (127) · Cardiovascular Diseases (121) · Diabetes Mellitus (105) · Raynaud Disease (80) · Coronary Artery Disease (78) · Arterial Occlusive Diseases (73) · Vascular Diseases (68) · Diabetic Foot (56) · Stroke (50) · Motor Activity (49) · Ischemia (46)
Vascular Diseases (2007) · Cardiovascular Diseases (1954) · Arteriosclerosis (1604) · Arterial Occlusive Diseases (1566) · Atherosclerosis (1481) · Pathological Conditions, Signs and Symptoms (845) · Pathologic Processes (523) · Disease Attributes (392) · Signs and Symptoms (383) · Chronic Disease (380) · Ischemia (380) · Peripheral Arterial Disease (315) · Endocrine System Diseases (182) · Nutritional and Metabolic Diseases (182)
Angioplasty (43) · Aspirin (43) · Exercise (37) · Clopidogrel (36) · Cilostazol (24) · Rivaroxaban (20) · Angioplasty, Balloon (18) · Standard of Care (18) · Stents (16) · Atherectomy (14) · Saline Solution (14) · Sodium Chloride (14) · Ticagrelor (13) · Control Groups (11) · Exercise Therapy (8)
Northwestern University (30) · University Hospital, Angers (30) · Medtronic Endovascular (24) · Flanders Medical Research Program (22) · Abbott Medical Devices (20) · C. R. Bard (20) · National Heart, Lung, and Blood Institute (NHLBI) (18) · Spectranetics Corporation (16) · VA Office of Research and Development (16) · Cook Group Incorporated (15) · Boston Scientific Corporation (14) · W.L.Gore & Associates (14) · University of Nebraska (13) · Bayer (12) · Biotronik AG (12)
United States (676) · Germany (232) · France (174) · United Kingdom (121) · China (120) · Belgium (112) · Italy (110) · Austria (97) · Canada (79) · Netherlands (72) · Spain (67) · South Korea (54) · Brazil (51) · Switzerland (47) · Australia (46)
Marc Bosiers, MD (16) · Koen Deloose, MD (14) · Thomas Zeller, MD (13) · Mary McDermott, MD (12) · Dierk Scheinert, MD (11) · Gunnar Tepe, MD (9) · Marianne Brodmann, MD (9) · Andrew Holden, MD (8) · Jihad Mustapha, MD (8) · Subhash Banerjee, MD (6) · Kenneth Rosenfield, MD (5) · Mary M McDermott, MD (5) · Pierre Abraham, MD, PhD (5)
PMID 42573020, PMID 42035974, PMID 31567024, PMID 33025243, PMID 35802393, PMID 36588397, PMID 36645250, PMID 30690141, PMID 31543165, PMID 36137674, PMID 37929840, PMID 39968829, PMID 17223489, PMID 18272892, PMID 21262997, PMID 23583245, PMID 23915883, PMID 25237048, PMID 25472980, PMID 26062950, PMID 31926836, PMID 34167675, PMID 40260835, PMID 41159585, PMID 16242558, PMID 16449620, PMID 17140820, PMID 17848483, PMID 18779447, PMID 20484101, PMID 21123095, PMID 21146749, PMID 21622669, PMID 21873417, PMID 21953370, PMID 22169682, PMID 22429908, PMID 22878166, PMID 23050152, PMID 23192918, PMID 23797811, PMID 24402764, PMID 24402839, PMID 25499305, PMID 25908725, PMID 26476467, PMID 26490645, PMID 26861113, PMID 27388828, PMID 27840332
2009 (5), 2017 (4), 2005 (3), 2014 (3), 2023 (3), 2025 (3), 2019 (2), R01AG006244 (2), R01HL075774 (2), R01HL098909 (2), 1IK2RX003546-01A2 (1), 1RC2HL101515-01 (1), 2004 (1), 2008 (1), 2016 (1)