16 completed, 6 unknown, 4 terminated, 2 not yet recruiting. 32 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 32 | Completed 16, Unknown 6, Terminated 4, Not yet recruiting 2, Recruiting 2, Active not recruiting 1, Suspended 1 |
Follow Intervertebral Disc Displacement: new trials by email Literature Review of Intervertebral Disc Displacement trials Research Report on Intervertebral Disc Displacement
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Comparing Three Epidural Steroid Injection Approaches for Lumbar Radicular Pain High-Volume Parasagittal Interlaminar Epidural Steroid Injection, Low-Volume Parasagittal Interlaminar Epidural Steroid Injection, Transforaminal epidural steroid injection - Lumbar Disc Herniation, Lumbosacral Radiculopathy | Phase 4 | Not yet recruiting | Benha University | 99 | 2026-10-01 | 2026-09-14 |
| Return to Activity After Surgery for Lumbar Disc Herniation Postoperative therapy - Lumbar Disc Herniation Surgery, Disc Herniation | Phase 4 | Not yet recruiting | Intrinsic Therapeutics | 120 | 2026-06-30 | 2026-06-25 |
| Dexamethasone as Adjuvant to Ropivacaine in Wound Infiltration for Postoperative Analgesia Following Spinal Surgery Ropivacaine 0.75% Injectable Solution, dexamethasone 8mg - Lumbar Spinal Stenosis, Lumbar Disc Herniation | Phase 4 | Completed | University Hospital Fattouma Bourguiba | 60 | 2023-01-01 | 2023-05-23 |
| Impact of Transforaminal Epidural Steroid Injection in Lumbar Disc Prolpse on Micro RNA-155 Serum Level transforaminal epidural injection., micro RNA-155 serum level - Lumbar Disc Herniation | Phase 4 | Completed | Beni-Suef University | 88 | 2022-12-01 | 2024-05-29 |
| Erector Spinae Plane Block as Pain Management After Lumbar Fusion Surgery Ropivacaine Hydrochloride Injection, Sodium chloride - Spondylolisthesis, Lumbar Disc Herniation | Phase 4 | Completed | Ilse van de Wijgert | 76 | 2022-06-01 | 2024-04-17 |
| Short-term Effectiveness of Gabapentin Versus Placebo in Acute Lumbosacral Radiculalgia by Herniation Disc (GRADE) Gabapentin 300mg, PLACEBO - Radiculopathy of Lumbosacral Spine Due to Disc Disorder | Phase 4 | Completed | Lille Catholic University | 144 | 2022-02-02 | 2026-04-21 |
| Regional Anesthesia in Minimally Invasive Lumbar Spine Surgery Bupivacaine-Epinephrine 0.25%-1:200,000 Injectable Solution plus clonidine, normal saline - Lumbar Spinal Stenosis, Lumbar Disc Herniation | Phase 4 | Recruiting | John O'Toole | 125 | 2022-02-01 | 2026-02-17 |
| Plane Block vs Intravenous Patient Controlled Analgesia Erector spina plane block (ESP), Modified thoracolumbar interfacial plane block (MTI), Intravenous patient controlled analgesia (IV-PCA) - Lumbar Disc Herniation | Phase 4 | Completed | Diskapi Teaching and Research Hospital | 81 | 2020-07-01 | 2020-11-09 |
| Subjective Intraoperative Use of Epidural Steroid Administration Following Discectomy Dexamethasone, saline 0.9% - Lumbar Disc Herniation | Phase 4 | Recruiting | University of Missouri-Columbia | 200 | 2019-11-21 | 2026-06-03 |
| Efficacy and Safety of Ultrasound-guided Lateral Thoracolumbar Interfascial Plane Block (TLIPB) for Postoperative Pain in Patients Undergoing Herniated Lumbar Disc Surgery PCIA group, Lateral TLIPB group - Postoperative Pain, Lumbar Disc Surgery | Phase 4 | Unknown | First Affiliated Hospital of Chongqing Medical University | 100 | 2019-08-01 | 2019-05-15 |
| Liposomal Bupivacaine in One-level Instrumented Posterior Spinal Fusion Liposomal bupivacaine - Lumbar Spinal Stenosis, Lumbar Disc Herniation | Phase 4 | Suspended | Allina Health System | 60 | 2019-01-26 | 2024-12-11 |
| Effectiveness of Cervical Transforaminal Epidural Steroid Injection Cervical Transforaminal Epidural Injection with dexamethasone sodium phosphate - Cervical Radiculopathy, Cervical Spondylosis | Phase 4 | Completed | University of Utah | 33 | 2018-10-23 | 2024-04-10 |
| Role Of Pregabalin To Decrease Postoperative Pain In Microdiscectomy Pregabalin 75mg, Placebo - Pain, Nerve, Prolapsed Intervertebral Disc | Phase 4 | Completed | Ziauddin University | 84 | 2018-06-04 | 2020-12-04 |
| Pentoxifylline and Lumbar Radiculopathy Pentoxifylline Oral Tablet, Ibuprofen - Lumbar Radiculopathy, Lumbar Disc Herniation | Phase 4 | Active not recruiting | St Joseph University, Beirut, Lebanon | 67 | 2018-06-01 | 2025-05-21 |
| A Post Marketing Surveillance Study 6mm annular closure device - Lumbar Disc Herniation, Annular Disc Tear | Phase 4 | Unknown | Intrinsic Therapeutics | 20 | 2018-01-16 | 2024-03-15 |
| A Prospective Study to Compare Bupivacaine and Exparel Versus Bupivacaine or Exparel Alone for Postoperative Pain Relief Exparel, Bupivacaine - Low Back Pain, Lumbosacral Radiculopathy | Phase 4 | Terminated | Virtua Health, Inc. | 19 | 2016-12-01 | 2021-01-06 |
| Post Market Non-Inferiority Study Comparing Triojection® to Discectomy for Lumbar Disc Herniation Triojection, Surgical discectomy - Lumbar Disc Herniation | Phase 4 | Unknown | Minimus Spine, Inc | 49 | 2015-07-01 | 2018-06-06 |
| Percutaneous HydroDiscectomy Compared to TESI for Radiculopathy Percutaneous Hydrodiscectomy, TESI - Lumbar Herniated Disc | Phase 4 | Terminated | Montefiore Medical Center | 4 | 2015-01-01 | 2020-03-02 |
| Perioperative Outcome of Corticosteroids in Transforaminal Endoscopic Lumbar Discectomy 40 mg Triamcinolone acetate 1 cc, Placebos - Lumbar Disc Herniation | Phase 4 | Completed | Ramathibodi Hospital | 30 | 2014-05-01 | 2017-09-06 |
| Percutaneous Transforaminal Endoscopic Discectomy vs Microendoscopic Discectomy for Treatment of Lumbar Disc Herniation Percutaneous transforaminal endoscopic discectomy (PTED), Microendoscopic discectomy (MED) - Lumbar Herniated Disc | Phase 4 | Unknown | Third Affiliated Hospital, Sun Yat-Sen University | 125 | 2013-10-01 | 2017-04-20 |
Showing 20 of 32. Sign in to see all of them.
Spinal Stenosis (9) · Spondylolisthesis (7) · Low Back Pain (5) · Radiculopathy (4) · Intervertebral Disc Degeneration (3) · Intervertebral disc disease (3) · Pain, Postoperative (3) · Spondylosis (3) · Constriction, Pathologic (1) · Failed Back Surgery Syndrome (1) · Neuralgia (1) · Ossification of Posterior Longitudinal Ligament (1) · Sciatica (1) · Spinal Diseases (1)
Bone Diseases (32) · Hernia (32) · Musculoskeletal Diseases (32) · Pathological Conditions, Anatomical (32) · Pathological Conditions, Signs and Symptoms (32) · Spinal Diseases (31) · Neurologic Manifestations (11) · Pain (11) · Signs and Symptoms (11) · Back Pain (6) · Spondylolysis (6) · Nervous System Diseases (5) · Neuromuscular Diseases (5) · Pathologic Processes (5) · Peripheral Nervous System Diseases (5)
Pregabalin (4) · Bupivacaine (2) · Dexamethasone (2) · Diskectomy (2) · Laminectomy (2) · Ropivacaine (2) · Sodium Chloride (2) · Acetaminophen (1) · Analgesia, Patient-Controlled (1) · Calcium Dobesilate (1) · Clonidine (1) · Gabapentin (1) · Ibuprofen (1) · Morphine (1) · Nerve Block (1)
Dartmouth-Hitchcock Medical Center (3) · Intrinsic Therapeutics (3) · Montefiore Medical Center (2) · Allina Health System (1) · Amniox Medical, Inc. (1) · Anulex Technologies, Inc. (1) · Asker & Baerum Hospital (1) · Benha University (1) · Beni-Suef University (1) · Diskapi Teaching and Research Hospital (1) · First Affiliated Hospital of Chongqing Medical University (1) · Ilse van de Wijgert (1) · John O'Toole (1) · Lille Catholic University (1) · Medtronic Spinal and Biologics (1)
United States (14) · China (3) · Germany (3) · Netherlands (3) · Belgium (2) · Egypt (2) · France (2) · Switzerland (2) · Austria (1) · Greece (1) · Italy (1) · Lebanon (1) · Norway (1) · Pakistan (1) · South Korea (1)
James N. Weinstein, DO, MS (3) · Benjamin W. Friedman, MD, MS (1) · Christopher Alcala-Marquez, MD (1) · David H Kim, MD (1) · Don Kim Moore, MD (1) · Dongsheng Huang, MD (1) · Jin Sup Yeom, MD, PhD (1) · John O'Toole, MD (1) · Joseph Maarrawi, MD, PhD (1) · Josip Buric, MD (1) · Khalid M Malik, MD (1) · Limin Rong, M.D. (1)
PMID 22048651, PMID 11840097, PMID 12177541, PMID 12925248, PMID 17119140, PMID 17119141, PMID 17413463, PMID 17538085, PMID 18287602, PMID 18758356, PMID 18777603, PMID 19018250, PMID 19075203, PMID 19487505, PMID 19755935, PMID 20453723, PMID 21311402, PMID 21358354, PMID 21385158, PMID 21841518, PMID 21971123, PMID 22791040, PMID 23392414, PMID 24885519, PMID 24916651, PMID 25692369, PMID 25996534, PMID 26424336, PMID 28894388, PMID 28962912, PMID 29102751, PMID 29303469, PMID 29538243, PMID 29730458, PMID 29845327, PMID 29927860, PMID 29983583, PMID 30059778, PMID 30280130, PMID 31029989, PMID 31089894, PMID 31689835, PMID 33085021, PMID 34882183, PMID 35378590, PMID 36083850, PMID 36114871, PMID 40230811, PMID 40601485, PMID 41137125
U01AR045444 (3), 2005 (1)