292 completed, 38 unknown, 36 recruiting, 36 terminated. 445 Phase 1, 167 Phase 2.
Follow Inflammation: new trials by email Literature Review of Inflammation trials Research Report on Inflammation
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Bioengineered Penile Tissue Constructs for Irreversibly Damaged Penile Corpora Autologous tissue engineered corpora - Urologic Diseases, Male Urogenital Diseases | Phase 1 | Not yet recruiting | Wake Forest University Health Sciences | 10 | 2027-01-01 | 2026-10-23 |
| Minocycline In Neurocognitive Outcomes - Sickle Cell Disease Minocycline, Placebo - Sickle Cell Disease, Cognitive Impairment | Phase 1 | Not yet recruiting | University of Cincinnati | 30 | 2026-12-01 | 2026-05-14 |
| CLL-1/CD70 Dual-Target CAR-T Cell Therapy for Acute Myeloid Leukemia CLL-1-CD70 CAR-T Cell Injection - Acute Myeloid Leukemia (AML), Relapsed/Refractory Acute Myeloid Leukemia | Phase 1 | Not yet recruiting | Liping Dou | 12 | 2026-11-30 | 2026-10-27 |
| "IL-1β Blockade to Prevent Immunothrombosis in Recipients of a Pancreatic Organ" Anakinra 100Mg/0.67Ml Inj Syringe - Pancreatic Transplant | Phase 1 / Phase 2 | Recruiting | Nantes University Hospital | 15 | 2026-10-07 | 2026-10-13 |
| Pre-emptive Anakinra for Cytokine Event Reduction Anakinra (Kineret®) - B-Acute Lymphoblastic Leukemia, CAR-T Cell Therapy | Phase 1 / Phase 2 | Withdrawn | Kevin McNerney | 2026-10-01 | 2026-08-13 | |
| [11C]PS13 PET Imaging of Neuroinflammation in Heart Failure With Reduced Ejection Fraction [11C]PS13: [carbon-11]PS13; COX-1 PET radioligand, Sacubitril-Valsartan - Heart Failure With Reduced Ejection Fraction, Cognitive Impairment, Mild | Phase 1 | Not yet recruiting | Stony Brook University | 18 | 2026-10-01 | 2026-10-02 |
| CLL-1-Targeted In Vivo CAR-T Cell Immunotherapy for Relapsed/Refractory Acute Myeloid Leukemia SL1CC Injection - Relapsed/Refractory Acute Myeloid Leukemia (AML), Acute Myeloid Leukemia (AML) | Phase 1 | Not yet recruiting | Liping Dou | 12 | 2026-10-01 | 2026-10-02 |
| Safety, Tolerability, and Pharmacodynamic Exploration of Orelabrutinib in Patients With Amyotrophic Lateral Sclerosis (ALS) Orelabrutinib - Amyotrophic Lateral Sclerosis (ALS) | Phase 1 | Not yet recruiting | Liu Qing | 12 | 2026-10-01 | 2026-10-15 |
| Safely Quenching Complement in Stroke Survivors Pegcetacoplan Injection [Empaveli] - Acute Ischemic Stroke, Cerebral Infarction | Phase 1 | Not yet recruiting | Columbia University | 20 | 2026-10-01 | 2026-04-29 |
| Genistein for the Reduction of Adverse Cardiovascular Events (GRACE) Genistein (Unconjugated Isoflavones 100), Placebo - HIV, Vascular Disease | Phase 1 / Phase 2 | Not yet recruiting | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | 60 | 2026-09-30 | 2026-08-25 |
| Interleukine-2 (IL-2) Plus Semaglutide in Alzheimer's Disease IL-2 (Aldesleukin), Semaglutide Plus IL-2, Placebo - Alzheimer Dementia (AD) | Phase 1 / Phase 2 | Recruiting | The Methodist Hospital Research Institute | 30 | 2026-09-01 | 2026-09-23 |
| Therapeutic Approach of Repeated Transient Blood-brain Barrier Opening in Amyotrophic Lateral Sclerosis. SonoCloud-4 (SC4) device - Amyotrophic Lateral Sclerosis, Charcot Disease | Phase 1 / Phase 2 | Recruiting | Assistance Publique - Hôpitaux de Paris | 23 | 2026-07-15 | 2026-08-10 |
| Labile Iron Removal by Adding the Iron Chelator MEX-CD1 to Dialysate in Sepsis-Associated Acute Kidney Injury Continuous veino-veinous dialysis with iron-chelator supplemented dialysate - Acute Kidney Injury, Sepsis | Phase 1 / Phase 2 | Recruiting | Centre Hospitalier Universitaire de Nīmes | 14 | 2026-06-04 | 2026-06-05 |
| A Study of Psychedelics in Healthy Older Adults With Low Well-being Psilocybin (drug), Dextromethorphan (DXM) - Anhedonia in Healthy Volunteers, Older Adults (50-90 Years) | Phase 1 | Recruiting | Jennifer Mitchell | 80 | 2026-06-01 | 2026-09-09 |
| A Multicenter Clinical Study of Romiplostim N01 in the Treatment of Sepsis-related Thrombocytopenia Administer Romiplostim treatment., Administer recombinant human thrombopoietin therapy - Sepsis | Phase 1 | Not yet recruiting | Shanghai 10th People's Hospital | 280 | 2026-06-01 | 2026-05-19 |
| Bispecific CAR T Cells for B-cell Malignancies (BaseCAR-01 Trial) Experimental Intervention - B Cell Malignancies, B-cell Leukemia | Phase 1 | Not yet recruiting | University Hospital, Basel, Switzerland | 12 | 2026-06-01 | 2025-12-24 |
| Hormones, Outcomes, and Pain Pathways in Exercise Study Interventional Sports bra - Breast Pain, Mastalgia | Phase 1 | Recruiting | University of Houston | 140 | 2026-05-17 | 2026-06-02 |
| Racecadotril for Organ Injury in Sepsis Patients Racecadotril, Water (Placebo) - Sepsis | Phase 1 / Phase 2 | Enrolling by invitation | Zhujiang Hospital | 44 | 2026-05-06 | 2026-05-28 |
| Vancomycin and Acute Kidney Injury in Sepsis Treatment - Intervention personalized dosing adjustment of vancomycin - Sepsis | Phase 1 | Recruiting | Children's Hospital of Philadelphia | 20 | 2026-04-15 | 2026-05-18 |
| Soy Tomato Juice to Improve Outcomes in Pancreatitis Soy-tomato juice product, Will include a soy-tomato juice product to be consumed during the 4 week intervention phase. A total of about 12 ounces (administered in two small cans) of the juice will be consumed - Recurrent Acute Pancreatitis, Chronic Pancreatitis | Phase 1 / Phase 2 | Recruiting | Ohio State University | 35 | 2026-04-02 | 2026-10-20 |
Showing 20 of 445. Sign in to see all of them.
Sepsis (96) · Shock, Septic (41) · Cytokine Release Syndrome (20) · Neuroinflammatory Diseases (18) · COVID-19 (16) · Arthritis, Rheumatoid (13) · Pain (11) · Atherosclerosis (10) · Critical Illness (9) · Insulin Resistance (9) · Malaria (9) · Parasitemia (9) · Respiratory Distress Syndrome (9) · Systemic Inflammatory Response Syndrome (9)
Pathological Conditions, Signs and Symptoms (445) · Pathologic Processes (441) · Infections (178) · Systemic Inflammatory Response Syndrome (157) · Shock (68) · Respiratory Tract Diseases (59) · Immune System Diseases (54) · Nervous System Diseases (54) · Lung Diseases (51) · Sepsis (46) · Cardiovascular Diseases (41) · Skin and Connective Tissue Diseases (40) · Signs and Symptoms (38) · Vascular Diseases (37)
Saline Solution (9) · Ascorbic Acid (6) · Bronchoscopy (6) · Lipopolysaccharides (6) · Aspirin (5) · Interleukin 1 Receptor Antagonist Protein (5) · Meropenem (5) · Endotoxins (4) · Melatonin (4) · Minocycline (4) · Propofol (4) · Simvastatin (4) · Sodium Chloride (4) · Sugars (4) · Vitamin D (4)
National Institute of Allergy and Infectious Diseases (NIAID) (13) · GlaxoSmithKline (12) · National Institute of Mental Health (NIMH) (10) · Novo Nordisk A/S (10) · Radboud University Medical Center (7) · University of Florida (7) · Bayer (5) · National Eye Institute (NEI) (5) · University of California, Los Angeles (5) · Vanderbilt University (5) · Emory University (4) · Indiana University (4) · Medical University of Vienna (4) · Phillip Brian Smith (4) · Sandoz (4)
United States (218) · Netherlands (27) · United Kingdom (23) · China (21) · Germany (19) · Canada (17) · Australia (13) · Sweden (11) · Belgium (7) · France (7) · Mexico (7) · Brazil (6) · Austria (5) · Denmark (5) · Egypt (5)
Robert B Innis, M.D. (6) · Antonio Abbate, MD, PhD (3) · Nehman Makdissy, Professor (3) · Paul D. Larsen, M.D. (3) · Yoghatama Cindya Zanzer, MSc (3) · Alan E Jones, MD (2) · Andrew D Luster, M.D., Ph.D. (2) · Anette Karlsen, MSc (2) · Iztok Potocnik, MD, MSC (2)
PMID 25749867, PMID 29749279, PMID 10379020, PMID 10415784, PMID 12563677, PMID 14719037, PMID 15663512, PMID 15713907, PMID 16164444, PMID 16319269, PMID 16864730, PMID 17181919, PMID 17551901, PMID 17621602, PMID 17660031, PMID 17662768, PMID 17954801, PMID 18097874, PMID 18433844, PMID 18492739, PMID 18846389, PMID 19056593, PMID 19105791, PMID 19234342, PMID 19320056, PMID 19397687, PMID 19417610, PMID 19453649, PMID 19998041, PMID 20084502, PMID 20444270, PMID 20846424, PMID 20920189, PMID 20976161, PMID 21131395, PMID 21211004, PMID 21371308, PMID 21396235, PMID 21399490, PMID 21593349, PMID 21806852, PMID 22028728, PMID 22340260, PMID 22438931, PMID 22465313, PMID 22491916, PMID 22545014, PMID 22569355, PMID 22666356, PMID 22666474
2008 (4), 2019 (3), 2009 (2), 2014 (2), 2016 (2), K01AA026005 (2), U19AI095261 (2), 1KL2RR031989-01 (1), 1RF1AG051514 (1), 2015 (1), 2023 (1), 2025 (1), K01AG072049 (1), K12CA120780 (1), K12TR005104 (1)