6 completed, 5 unknown, 2 terminated, 2 withdrawn. 17 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 17 | Completed 6, Unknown 5, Terminated 2, Withdrawn 2, Active not recruiting 1, Not yet recruiting 1 |
Follow Enterocolitis: new trials by email Literature Review of Enterocolitis trials Research Report on Enterocolitis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Emerging Indications for Hyperbaric Oxygen Treatment Hyperbaric oxygen treatment (HBOT), 100% Oxygen - Post-COVID-19 Condition, Ulcerative Colitis | Phase 4 | Not yet recruiting | Jay C. Buckey Jr. | 100 | 2026-11-01 | 2026-09-09 |
| Early Hydrocortisone Versus Regular Treatment in Shock in Extremely Preterm Neonates - an Open Randomized Controlled Trial Intravascular Hydrocortisone (stress dosage): 1 mg/k/dose each 8 hours for 5 days, Vasoactive drug therapies - Shock, Preterm Birth Complication | Phase 4 | Active not recruiting | Coordinación de Investigación en Salud, Mexico | 76 | 2025-02-01 | 2025-11-25 |
| Effect of Antibiotics on Enteric Neurons and Glia Amoxicillin Oral Capsule - Antibiotic Enterocolitis | Phase 4 | Completed | Rockefeller University | 10 | 2023-06-23 | 2026-03-12 |
| Effect of Oral N-Acetyl Cysteine in Prevention of Necrotizing Enterocolitis in Preterm Neonates With Feeding Intolerance oral n-acetyl cysteine, placebo - Preterm Neonates and Feeding Intolerance, Necrotizing Enterocolitis | Phase 4 | Unknown | Ain Shams University | 100 | 2023-01-01 | 2024-01-12 |
| Bezlotoxumab Versus FMT for Multiple Recurrent CDI Bezlotoxumab, Fecal Microbiota Transplantation (FMT), Vancomycin oral - Clostridium Infections, Clostridioides Difficile | Phase 4 | Withdrawn | Leiden University Medical Center | 2022-01-01 | 2023-03-28 | |
| The Efect of Azithromicyn on Bronchopulmonary Displasia in Extremely Preterm and Very Preterm Infant Azithromycin Powder - Bronchopulmonary Dysplasia, Intraventricular Hemorrhage | Phase 4 | Completed | Universitas Indonesia | 120 | 2021-06-08 | 2024-03-08 |
| Zinc Supplementation on Very Low Birth Weight Infant Zinc Sulfate, Placebos - Early-Onset Sepses, Neonatal, Periventricular Haemorrhage Neonatal | Phase 4 | Unknown | Fakultas Kedokteran Universitas Indonesia | 364 | 2019-08-20 | 2019-08-15 |
| Comparing the Effectiveness of IV Bezlotoxumab Versus Placebo in Decreasing Morbidity and Mortality in Patients With Fulminant C. Diff Requiring Surgery. Bezlotoxumab, Normal Saline - Clostridia Difficile Colitis, Clostridium; Sepsis | Phase 4 | Terminated | Ohio State University | 5 | 2019-08-19 | 2026-06-18 |
| Effect of Melatonin on Feeding Intolerance and Incidence of Necrotizing Enterocolitis in Preterm Infants Melatonin 20 mg, Traditional antibiotic treatment - Preterm Infant, Feeding Intolerance | Phase 4 | Completed | Ain Shams University | 90 | 2018-12-24 | 2020-03-11 |
| Impact of Oral Antibiotic Treatment on C. Difficile Fidaxomicin, Metronidazole, Vancomycin - C. Difficile, Diarrhea | Phase 4 | Completed | Duke University | 33 | 2014-06-10 | 2019-10-02 |
| Withholding Feeds During Red Blood Cell Transfusion and TRAGI Withholding feeds, feeding during transfusion - Transfusion, Feeding During Transfusion | Phase 4 | Unknown | Zekai Tahir Burak Women's Health Research and Education Hospital | 150 | 2014-02-01 | 2014-05-07 |
| Clostridial Infection and Oral Lavage -Improving Treatment Before Illness Becomes Severe Nu-Lytely - Clostridium Difficile Colitis | Phase 4 | Unknown | Ascension Health | 200 | 2012-06-01 | 2012-08-17 |
| Intestinal Inflammation in Ankylosing Spondylitis and the Effects of Adalimumab on Mucosal Healing Adalimumab - Spondyloarthritis, Enterocolitis | Phase 4 | Completed | Regionshospitalet Silkeborg | 30 | 2010-10-01 | 2014-12-02 |
| The Role of Short-course Ceftriaxone Therapy in the Treatment of Severe Nontyphoidal Salmonella Enterocolitis ceftriaxone - Diarrhea | Phase 4 | Unknown | Chang Gung Memorial Hospital | 200 | 2010-08-01 | 2011-01-17 |
| Addition of Lactobacillus to Metronidazole in Treatment of CDAD Lactobacillus GG - Enterocolitis, Pseudomembranous Colitis | Phase 4 | Withdrawn | Michael E. DeBakey VA Medical Center | 2008-08-01 | 2017-05-10 | |
| Effect of Probiotics (Bio-Three) in Children's Enterocolitis Biothree - Diarrhea, Enteritis | Phase 4 | Completed | Chang Gung Memorial Hospital | 300 | 2006-02-01 | 2008-09-19 |
| The Role of Synbiotics in Reducing Post-Operative Infections in Patients Undergoing Cardiac Surgery: A Pilot Study Synbiotic 2000 - Surgical Wound Infection, Cystitis | Phase 4 | Terminated | Beth Israel Medical Center | 40 | 2005-11-01 | 2007-11-01 |
Enterocolitis, Pseudomembranous (7) · Enterocolitis, Necrotizing (6) · Diarrhea (3) · Bronchopulmonary Dysplasia (2) · Neonatal Sepsis (2) · Premature Birth (2) · Bacteremia (1) · Calciphylaxis (1) · Clostridium Infections (1) · Colitis, Ulcerative (1) · Craniocerebral Trauma (1) · Crohn Disease (1) · Cystitis (1) · Enteritis (1)
Digestive System Diseases (17) · Gastroenteritis (17) · Gastrointestinal Diseases (17) · Intestinal Diseases (17) · Infections (9) · Pathological Conditions, Signs and Symptoms (8) · Bacterial Infections (7) · Bacterial Infections and Mycoses (7) · Gram-Positive Bacterial Infections (7) · Clostridium Infections (6) · Pathologic Processes (5) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (4) · Female Urogenital Diseases and Pregnancy Complications (4) · Inflammation (4)
Vancomycin (2) · bezlotoxumab (2) · Acetylcysteine (1) · Adalimumab (1) · Amoxicillin (1) · Benchmarking (1) · Ceftriaxone (1) · Fecal Microbiota Transplantation (1) · Fidaxomicin (1) · Lacteol (1) · Melatonin (1) · Metronidazole (1) · Oxygen (1) · Saline Solution (1) · Zinc Sulfate (1)
Ain Shams University (2) · Chang Gung Memorial Hospital (2) · Ascension Health (1) · Beth Israel Medical Center (1) · Coordinación de Investigación en Salud, Mexico (1) · Duke University (1) · Fakultas Kedokteran Universitas Indonesia (1) · Jay C. Buckey Jr. (1) · Leiden University Medical Center (1) · Michael E. DeBakey VA Medical Center (1) · Ohio State University (1) · Regionshospitalet Silkeborg (1) · Rockefeller University (1) · Universitas Indonesia (1) · Zekai Tahir Burak Women's Health Research and Education Hospital (1)
United States (6) · Egypt (2) · Taiwan (2) · Denmark (1) · Indonesia (1) · Mexico (1) · Netherlands (1) · Turkey (Türkiye) (1)
Begum Aydin, PhD (1) · Bent Deleuran, M.D. (1) · Chien-Chang Chen, MD (1) · Daniel J Sexton, MD (1) · Daniel M Musher, M.D. (1) · David S Seres, MD (1) · Henning Glerup, M.D. (1) · Henri Azis, Master (1) · J van Prehn (1) · Jay Buckey (1)