Gastroenteritis: Clinical Trials

2769 completed, 976 unknown, 686 recruiting, 517 terminated. 1483 Not applicable, 967 Phase 2, 677 Phase 3, 485 Phase 1, 407 Phase 4.

By phase and status

Phase	Trials	Status
Not applicable	1483	Completed 644, Unknown 319, Recruiting 193, Terminated 117, Not yet recruiting 89, Withdrawn 50, Active not recruiting 49, Enrolling by invitation 15, Suspended 7
Phase 2	967	Completed 479, Terminated 169, Recruiting 112, Unknown 89, Withdrawn 48, Active not recruiting 41, Not yet recruiting 21, Enrolling by invitation 5, Suspended 3
Phase 3	677	Completed 389, Terminated 101, Unknown 73, Recruiting 51, Active not recruiting 33, Withdrawn 19, Not yet recruiting 8, Enrolling by invitation 2, Suspended 1
Phase 1	485	Completed 275, Terminated 57, Unknown 48, Recruiting 42, Withdrawn 27, Not yet recruiting 21, Active not recruiting 11, Enrolling by invitation 3, Suspended 1
Phase 4	407	Completed 204, Unknown 63, Terminated 43, Recruiting 41, Not yet recruiting 25, Withdrawn 18, Active not recruiting 11, Enrolling by invitation 2
Early Phase 1	65	Unknown 22, Completed 16, Recruiting 8, Not yet recruiting 7, Withdrawn 5, Terminated 3, Active not recruiting 2, Enrolling by invitation 2

Follow Gastroenteritis: new trials by email Literature Review of Gastroenteritis trials Research Report on Gastroenteritis

Trials newest first · largest first

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

Trial	Phase	Status	Sponsor	Enrollment	Start	Updated
Dose Ranging Study to Evaluate the Safety, Efficacy, and Pharmacokinetics of Budesonide Rectal Foam in Pediatric Patients Aged 5 to 17 Years With Active, Mild to Moderate Distal Ulcerative Colitis High dose budesonide rectal foam, Low dose budesonide rectal foam, Matching placebo rectal foam - Ulcerative Colitis	Phase 4	Not yet recruiting	Bausch Health Americas, Inc.	100	2029-06-01	2026-10-06
Methadone as an Alternative Treatment for Children Underdoing HSCT PCA plus methadone (Experimental), PCA Alone (SOC) - Leukemia, Aplastic Anemia	Phase 3	Suspended	University of Texas Southwestern Medical Center	60	2028-01-01	2025-10-23
ACT for Veterans With IBD and Mental Health Challenges Acceptance and Commitment Therapy - Inflammatory Bowel Diseases, Crohn's Disease	Not applicable	Not yet recruiting	VA Office of Research and Development	50	2028-01-01	2026-02-09
A Mindfulness-based Stress Reduction Program for IBD Mindfulness based stress reduction, Active Control - Inflammatory Bowel Disease (Crohn&Amp;#39;s Disease and Ulcerative Colitis)	Not applicable	Not yet recruiting	Nova Scotia Health Authority	70	2027-09-01	2026-09-08
Digital Mind Body Intervention Among Black and Hispanic Patients Living With Inflammatory Bowel Disease Digital Mind Body Intervention mobile application - Crohn's Disease, Ulcerative Colitis	Not applicable	Not yet recruiting	Montefiore Medical Center	40	2027-07-01	2026-09-14
Adapted Physical Activity for Persistent Fatigue in Patients With Inflammatory Bowel Disease in Remission Adapted Physical Activity, Usual Care - Inflammatory Bowel Diseases (IBD), Fatigue	Not applicable	Not yet recruiting	University Hospital, Grenoble	120	2027-06-01	2026-09-11
Piperacillin/Tazobactam Versus Ceftriaxone and Metronidazole for Children With Perforated Appendicitis Piperacillin/Tazobactam, Ceftriaxone + Metronidazole - Appendicitis Perforated, Appendectomy, Laparoscopic	Phase 3	Not yet recruiting	McMaster Children's Hospital	180	2027-04-01	2026-10-09
ASAPP Study - Topical 5-ASA as Prophylaxis for Pouchitis in Ulcerative Colitis Patients After Pelvic Pouch Surgery 5-ASA, Placebo - Ulcerative Colitis (UC), Pouchitis	Phase 4	Not yet recruiting	University Hospital, Linkoeping	110	2027-04-01	2026-08-19
LMT503 First-in-human SAD, MAD, and FE Study LMT503, Placebo - Inflammatory Bowel Disease, Colitis, Ulcerative	Phase 1	Not yet recruiting	Lmito Therapeutics Inc.	72	2027-03-01	2026-09-01
Povidone-iodine Irrigation for Prevention of Intra-abdominal Abscess in Pediatric Perforated Appendicitis: a Multi-center Stepped Wedge Cluster Randomized Study Irrigation with PVI, Usual care - Acute, Perforated Appendicitis	Phase 4	Not yet recruiting	The University of Texas Health Science Center, Houston	1750	2027-03-01	2025-02-10
Efficacy and Safety of TRA16 Administered Orally in Patients With Enteric Hyperoxaluria (EH). TRA16, Placebo - Enteric Hyperoxaluria	Phase 2	Not yet recruiting	Wuhan Kangfude Urolithiasis Research Institute Co., Ltd.	30	2027-03-01	2026-10-13
Nitazoxanide as Adjunct Therapy in Mild-to-Moderate Ulcerative Colitis Nitazoxanide (NTZ) - Ulcerative Colitis (UC)	Phase 2 / Phase 3	Not yet recruiting	Tanta University	44	2027-01-01	2026-09-15
Perforated Appendicitis and Postoperative Antibiotics Pilot Trial Postoperative antibiotico-prophylaxis, No postoperative antibiotics - Perforated Appendicitis	Not applicable	Not yet recruiting	London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's	100	2027-01-01	2026-09-17
Safety and Efficacy of a STOPping Strategy Versus Classical Maintenance Dose of JAK Inhibitors in Deep Remission Patients With Ulcerative Colitis treatment withdrawal - Ulcerative Colitis in Remission	Phase 4	Not yet recruiting	Assistance Publique Hopitaux De Marseille	224	2027-01-01	2026-07-22
Biophysical Assessments of Acupuncture Points in Inflammatory Bowel Disease Inflammatory Bowel Disease (IBD)		Not yet recruiting	Brigham and Women's Hospital	100	2027-01-01	2026-10-20
Oral Aeromonas sp. MTB Phage Therapy for Pouchitis in Patients With Ulcerative Colitis (UC) MTB-targeted phage therapy - Pouchitis, UC - Ulcerative Colitis	Early Phase 1	Not yet recruiting	Jinling Hospital, China	12	2027-01-01	2026-10-22
Safety, Tolerability and PK of ATTO 1091 in Healthy Adult Volunteers and Patients With Ulcerative Colitis ATTO-1091, Placebo - Ulcerative Colitis (UC)	Phase 1	Not yet recruiting	Attovia Therapeutics Inc	96	2026-12-14	2026-09-15
Pilot Study of Salivary Bile Acids and Pepsin as Predictive Biomarkers of Reflux Disease After Sleeve Gastrectomy Reflux Disease, Gastro-Esophageal, Sleeve Gastrectomy		Not yet recruiting	Hospital de Mataró	60	2026-12-01	2026-05-26
Music and VR Effects on Pain, Anxiety, and Fear During Oral Mucositis Care in Leukaemic Children Music intervention, Virtual reality - Anxiety, Pain	Not applicable	Not yet recruiting	Ege University	45	2026-12-01	2026-05-19
Visualization of the Colon Through Use of the Magnetic Flexible Endoscope (MFE) in Participants With Inflammatory Bowel Disease (IBD) Magnetic Flexible Endoscope (MFE) - Inflammatory Bowel Disease (IBD), Colonoscopy	Not applicable	Not yet recruiting	Vanderbilt University Medical Center	6	2026-12-01	2026-08-20

Showing 20 of 5697. Sign in to see all of them.

Narrower conditions

Crohn Disease (1947)  ·  Colitis, Ulcerative (1792)  ·  Inflammatory Bowel Diseases (1547)  ·  Appendicitis (400)  ·  Eosinophilic Esophagitis (234)  ·  Enterocolitis, Necrotizing (222)  ·  Mucositis (208)  ·  Colitis (127)  ·  Diverticulitis (100)  ·  Diarrhea (96)  ·  Gastritis (91)  ·  Esophagitis (88)  ·  Colorectal Neoplasms (87)  ·  Arthritis, Rheumatoid (86)

Broader conditions

Digestive System Diseases (5646)  ·  Gastrointestinal Diseases (5615)  ·  Intestinal Diseases (4834)  ·  Inflammatory Bowel Diseases (2266)  ·  Colonic Diseases (2046)  ·  Colitis (1769)  ·  Pathological Conditions, Signs and Symptoms (887)  ·  Infections (726)  ·  Immune System Diseases (449)  ·  Pathologic Processes (449)  ·  Cecal Diseases (400)  ·  Intraabdominal Infections (396)  ·  Esophageal Diseases (378)  ·  Signs and Symptoms (373)

Interventions

Infliximab (147)  ·  Mesalamine (117)  ·  Adalimumab (109)  ·  vedolizumab (100)  ·  Fecal Microbiota Transplantation (85)  ·  Ustekinumab (66)  ·  Metronidazole (53)  ·  Appendectomy (48)  ·  Azathioprine (47)  ·  Blood Specimen Collection (47)  ·  Budesonide (43)  ·  Colonoscopy (39)  ·  Certolizumab Pegol (35)  ·  Probiotics (35)  ·  Endoscopy (33)

Sponsors

Takeda (96)  ·  AbbVie (74)  ·  Assiut University (69)  ·  Mayo Clinic (65)  ·  Pfizer (60)  ·  GlaxoSmithKline (57)  ·  Janssen Research & Development, LLC (46)  ·  Assistance Publique - Hôpitaux de Paris (41)  ·  Sixth Affiliated Hospital, Sun Yat-sen University (41)  ·  National Institute of Allergy and Infectious Diseases (NIAID) (35)  ·  AstraZeneca (34)  ·  Children's Hospital Medical Center, Cincinnati (34)  ·  Central Hospital, Nancy, France (30)  ·  Ferring Pharmaceuticals (30)  ·  Groupe d'Etude Therapeutique des Affections Inflammatoires Digestives (30)

Countries

United States (1798)  ·  Canada (612)  ·  France (603)  ·  China (506)  ·  United Kingdom (496)  ·  Italy (485)  ·  Germany (475)  ·  Belgium (390)  ·  Israel (389)  ·  Poland (386)  ·  Spain (368)  ·  Netherlands (362)  ·  South Korea (291)  ·  Hungary (275)  ·  Australia (271)

Top investigators

Arie Levine, MD (10)

Results publications

PMID 40243391, PMID 40357993, PMID 40013523, PMID 29380251, PMID 32445184, PMID 26893500, PMID 35648151, PMID 36124702, PMID 37368103, PMID 29850873, PMID 30476584, PMID 30739254, PMID 31077827, PMID 31599001, PMID 32816215, PMID 33684552, PMID 35792493, PMID 36342120, PMID 36526796, PMID 36931693, PMID 38425446, PMID 39778975, PMID 19735233, PMID 20195905, PMID 25996351, PMID 32635680, PMID 32766762, PMID 32870265, PMID 32964215, PMID 33127596, PMID 33324993, PMID 33513294, PMID 34614208, PMID 35380664, PMID 35380740, PMID 36150926, PMID 36208720, PMID 36336750, PMID 37224198, PMID 37402275, PMID 37560161, PMID 38096402, PMID 38310565, PMID 38778549, PMID 41264726, PMID 41763462, PMID 42248437, PMID 16339095, PMID 19596014, PMID 21129076

NIH funding

2023 (55), 2017 (44), 2016 (32), 2014 (30), 2025 (29), 2018 (28), 2015 (26), 2019 (25), 2009 (14), 2008 (11), 2004 (6), 2005 (4), U54AI117804 (4), UL1TR001082 (4), U10HD021364 (3)