414 completed, 53 unknown, 40 recruiting, 39 terminated. 194 Phase 3, 113 Phase 2, 85 Phase 4, 67 Not applicable, 67 Phase 1.
Follow Clostridium Infections: new trials by email Literature Review of Clostridium Infections trials Research Report on Clostridium Infections
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Clinical Trial of Resistant Potato Starch for Gut MDRO Decolonization Resistant Potato Starch, Maltodextrin - Clostridium Infections, Methicillin-resistant Staphylococcus Aureus (MRSA) | Phase 2 | Not yet recruiting | VA Office of Research and Development | 120 | 2027-01-01 | 2026-08-28 |
| Primary Prophylaxis of Clostridioides Difficile Infection With Oral Vancomycin Vancomycin (POC) - Clostridioides Difficile, Vancomycin Resistance Enterococcus Faecium | Phase 2 / Phase 3 | Withdrawn | University of Maryland, Baltimore | 2027-01-01 | 2026-07-29 | |
| Emerging Indications for Hyperbaric Oxygen Treatment Hyperbaric oxygen treatment (HBOT), 100% Oxygen - Post-COVID-19 Condition, Ulcerative Colitis | Phase 4 | Not yet recruiting | Jay C. Buckey Jr. | 100 | 2026-11-01 | 2026-09-09 |
| Observation of Immune Persistence in a Clinical Trial of an Adsorbed Tetanus Vaccine Previously vaccinated with TTVA, Previously vaccinated with TT - Tetanus | Not yet recruiting | CanSino Biologics Inc. | 240 | 2026-10-15 | 2026-09-08 | |
| PHASE 1 TRIAL OF Lm-LLO-TT AND GEMCITABINE IN UNRESECTABLE PANCREATIC DUCTAL ADENOCARCINOMA Lm-LLO-TT - Pancreas Cancer, Duct Cell Adenocarcinoma, Pancreatic Cancer | Phase 1 | Not yet recruiting | Loki Therapeutics, Inc. | 18 | 2026-10-15 | 2026-09-18 |
| A Clinical Study on Immunogenicity Persistence of Adsorbed 5-component Acellular Pertussis, Diphtheria and Tetanus Combined Vaccine Previously received the Tdcp vaccine at age 18 and older, Previously received the Tdcp vaccine at age 12-17, Previously received the Tdcp vaccine at age 6-11 - Diphtheria, Tetanus | Not yet recruiting | CanSino Biologics Inc. | 160 | 2026-10-15 | 2026-08-04 | |
| A Phase I/II Clinical Trial of the Diphtheria, Tetanus, Acellular Component Pertussis and Sabin Inactivated Poliomyelitis Vaccine Adsorbed Diphtheria, Tetanus, Acellular Component Pertussis and Sabin Inactivated Poliomyelitis Vaccine Adsorbed, Diphtheria, Tetanus and Acellular Component Pertussis Combined Vaccine, Diphtheria, Tetanus and Acellular Component Pertussis Combined Vaccine+Inactivated Poliomyelitis Vaccine Made From Sabin Strains - Diphtheria, Pertussis | Phase 1 / Phase 2 | Recruiting | Institute of Medical Biology, Chinese Academy of Medical Sciences | 380 | 2026-10-11 | 2026-10-23 |
| Study of BK1803 in Healthy Infants BK1803, GOBIK Aqueous Suspension Syringes, Bimmugen® Injection - Pertussis, Diphtheria | Phase 3 | Not yet recruiting | Tanabe Pharma Corporation | 344 | 2026-10-01 | 2026-08-28 |
| A Safety Trial to Evaluate an Orally Ingested Yeast Modified to Express a Tetra-specific Anti-toxin for Clostridioides Difficile FZ002, Placebo for FZ002 - Clostridium Difficile Infection | Phase 1 | Not yet recruiting | National Institute of Allergy and Infectious Diseases (NIAID) | 56 | 2026-09-17 | 2026-10-09 |
| Use of Fidaxomicin Compared to Vancomycin for Decolonization of C. Difficile in Patients With Inflammatory Bowel Disease Vancomycin (POC), Fidaxomicin - Inflammatory Bowel Disease (IBD), Clostridioides Difficile Infection | Phase 4 | Not yet recruiting | Brigham and Women's Hospital | 60 | 2026-09-01 | 2025-11-03 |
| Pilot Trial of Xylitol for C. Difficile De-Colonization in Patients With Inflammatory Bowel Disease Xylitol - Inflammatory Bowel Disease (IBD), Clostridioides Difficile Infection | Early Phase 1 | Not yet recruiting | Brigham and Women's Hospital | 69 | 2026-09-01 | 2025-12-16 |
| Xylitol Use for Decolonization of C. Difficile in Patients With IBD Xylitol, Placebo - Inflammatory Bowel Diseases, Clostridioides Difficile Infection | Phase 1 | Not yet recruiting | Brigham and Women's Hospital | 99 | 2026-08-01 | 2026-02-25 |
| A First in Human Study Investigating the Safety of an Unloaded and Loaded (With a Tetanus-containing Vaccine Booster) Microneedle Patch in Healthy Adults Microneedle Patch, Tetanus-containing vaccine - Vaccine Delivery, Tetanus | Phase 4 | Not yet recruiting | Microneedle Solutions Ltd | 30 | 2026-08-01 | 2026-06-03 |
| A Study on the Immune Response and Safety of a Combined Vaccine Against Diphtheria, Tetanus and Acellular Pertussis (dTpa) in Japanese Healthy Pregnant Women dTpa - Diphtheria-Tetanus-acellular Pertussis Vaccines | Phase 3 | Active not recruiting | GlaxoSmithKline | 102 | 2026-06-29 | 2026-09-08 |
| A Phase Ⅲ Clinical Study of SNA02-48 Injection SNA02-48, Human tetanus immunoglobulin (HTIG) - Tetanus | Phase 3 | Not yet recruiting | Sinovac Life Sciences Co., Ltd. | 600 | 2026-06-28 | 2026-06-08 |
| Role of Bile Acids and Microbiota in Clostridioides Difficile Infection in Ulcerative Colitis Feces collection - Ulcerative Colitis | Recruiting | Assistance Publique - Hôpitaux de Paris | 80 | 2026-06-09 | 2026-06-24 | |
| Lifestyle and Recurrent Clostridioides Difficile Infection (CDI) Health counseling sessions, Diet (control diet), Diet (experimental diet) - Clostridioides Difficile Infection | Not applicable | Recruiting | University of Michigan | 20 | 2026-06-05 | 2026-07-08 |
| Maternal Immunization With Tetanus Toxoid, Reduced Diphtheria Toxoid, Reduced-dose (2 µg) Recombinant Pertussis Vaccine (TdaP2gen) and Its Effect on the Immune Response in Thai Infants up to 15-18 Months Old Maternal TdaP2gen vaccine, Infant Acellular Pertussis-containing Vaccine, Infant Whole-cell Pertussis-containing Vaccine - Pertussis, Diphtheria | Phase 4 | Not yet recruiting | Chiang Mai University | 320 | 2026-05-26 | 2026-06-02 |
| Phase I Clinical Trial of Adsorbed Tetanus Vaccine Tetanus Vaccine, Adsorbed - Tetanus | Phase 1 | Active not recruiting | Aimei Vacin BioPharm (Zhejiang) Co., Ltd. | 80 | 2026-05-21 | 2026-09-22 |
| Long-Term Outcomes After CDI: FMT Versus Antibiotic-Only Treatment Clostridioides Difficile Infection | Not yet recruiting | Umeå University | 250 | 2026-05-01 | 2026-05-06 |
Showing 20 of 603. Sign in to see all of them.
Tetanus (303) · Diphtheria (243) · Whooping Cough (166) · Poliomyelitis (114) · Haemophilus Infections (106) · Hepatitis B (105) · Enterocolitis, Pseudomembranous (43) · Diarrhea (35) · Botulism (19) · Bacterial Infections (10) · Inflammatory Bowel Diseases (10) · Colitis, Ulcerative (9) · Infections (9) · Measles (9)
Bacterial Infections and Mycoses (603) · Gram-Positive Bacterial Infections (600) · Infections (594) · Bacterial Infections (593) · Actinomycetales Infections (244) · Corynebacterium Infections (243) · Gram-Negative Bacterial Infections (206) · Respiratory Tract Diseases (177) · Respiratory Tract Infections (175) · Digestive System Diseases (173) · Bordetella Infections (166) · Virus Diseases (163) · Nervous System Diseases (149) · Neuromuscular Diseases (134)
Tetanus Toxoid (61) · Vancomycin (54) · Fecal Microbiota Transplantation (38) · diphtheria-tetanus-acellular pertussis-inactivated poliovirus-Haemophilus influenzae b conjugate-hepatitis B vaccine (29) · Boostrix (25) · Diphtheria-Tetanus-acellular Pertussis Vaccines (24) · adacel (24) · Fidaxomicin (18) · Hiberix (12) · Pentavac (12) · Vaccines, Combined (11) · Saline Solution (10) · bezlotoxumab (10) · pentacel (10) · 13-valent pneumococcal vaccine (9)
GlaxoSmithKline (104) · Sanofi Pasteur, a Sanofi Company (60) · Sanofi (21) · National Institute of Allergy and Infectious Diseases (NIAID) (16) · CanSino Biologics Inc. (10) · Merck Sharp & Dohme LLC (10) · LG Chem (7) · Actelion (5) · Brigham and Women's Hospital (5) · Genzyme, a Sanofi Company (5) · Mayo Clinic (5) · Michael E. DeBakey VA Medical Center (5) · Zhuhai Trinomab Pharmaceutical Co., Ltd. (5) · Assistance Publique - Hôpitaux de Paris (4) · AstraZeneca (4)
United States (209) · Canada (67) · China (53) · Germany (31) · France (30) · Spain (25) · South Korea (23) · United Kingdom (21) · Italy (19) · Philippines (19) · Poland (17) · Sweden (15) · Denmark (14) · Finland (14) · Japan (14)
Daniel M Musher, M.D. (6) · Nasia Safdar, MD PhD (4) · Dina Kao, MD (3) · Ole Hyldegaard, MD, PhD (3) · Purna Kashyap, MD (3) · Raman Rao, MD (3) · Richard Greenberg, MD (3) · Anne Claire Marrast, MD (2) · Christine H Lee, MD (2) · Christine Lee, MD (2) · Chuanlin Wang, MD (2)
PMID 42286373, PMID 41245385, PMID 31411386, PMID 17716936, PMID 20657177, PMID 22306375, PMID 22752857, PMID 22752865, PMID 23323867, PMID 23715579, PMID 24599770, PMID 24762631, PMID 24799326, PMID 25882172, PMID 28121498, PMID 28340322, PMID 29538686, PMID 29680101, PMID 29788418, PMID 30060024, PMID 30227108, PMID 30455246, PMID 30460321, PMID 30709665, PMID 31628838, PMID 32099847, PMID 32376702, PMID 32504314, PMID 32747931, PMID 36661328, PMID 38941068, PMID 41483804, PMID 10440607, PMID 11171619, PMID 14670310, PMID 15882526, PMID 16511379, PMID 16760795, PMID 16816555, PMID 17051488, PMID 17090650, PMID 17954801, PMID 18431498, PMID 18752430, PMID 19095033, PMID 19117896, PMID 19133801, PMID 19952980, PMID 20089970, PMID 20189491
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