12 completed, 4 unknown, 2 active not recruiting, 2 terminated. 7 Phase 2, 4 Not applicable, 4 Phase 4, 3 Phase 1, 2 Early Phase 1.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Optimization of Bacterial Vaginosis Treatment in Women of Reproductive Age Longidaza, Metronidazole 500 mg - Bacterial Vaginosis | Phase 4 | Unknown | I.M. Sechenov First Moscow State Medical University | 100 | 2024-06-01 | 2025-04-09 |
| Fecal Microbiota Transplant and Re-introduction of Anti-PD-1 Therapy (Pembrolizumab or Nivolumab) for the Treatment of Metastatic Colorectal Cancer in Anti-PD-1 Non-responders Biopsy, Fecal Microbiota Transplantation, Fecal Microbiota Transplantation Capsule - Metastatic Colorectal Adenocarcinoma, Metastatic Small Intestinal Adenocarcinoma | Phase 2 | Active not recruiting | M.D. Anderson Cancer Center | 15 | 2021-02-22 | 2026-06-12 |
| PROJECT PREVENT: Metronidazole Antibiotic Per Vagina Before Hysterectomy: Is Additional Antibiotic Prophylaxis Beneficial? Metronidazole Vaginal - Post-Op Infection | Phase 4 | Active not recruiting | New York Medical College | 136 | 2020-07-15 | 2023-05-17 |
| Post-Endoscopic Infection Rate Notifications to Improve the Delivery of Care Option 1: National comparison, Option 2: National comparison with benchmarking - Infection | Not applicable | Completed | Johns Hopkins University | 303 | 2019-08-07 | 2023-06-23 |
| Prevention of Dry Socket by Means of Single Preoperative Antibiotics Compared to Conventional Therapy Amoxicillin 500 Mg, metronidazole 400mg, metronidazol 400mg and amoxicillin 500mg - Dry Socket | Phase 2 | Completed | Dow University of Health Sciences | 225 | 2018-10-01 | 2019-06-20 |
| Peritonsillar Abscess: Aspiration Versus Tonsillectomy a Chaud Aspiration, Tonsillectomy a chaud, Penicillin V + metronidazol (Penicillin allergy: Clindamycin alone) - Peritonsillar Abscess | Not applicable | Unknown | Odense University Hospital | 128 | 2017-11-10 | 2017-11-09 |
| Neomycin and Metronidazole Hydrochloride With or Without Polyethylene Glycol in Reducing Infection in Patients Undergoing Elective Colorectal Surgery Polyethylene Glycol, Neomycin, Metronidazole Hydrochloride - Colorectal Neoplasms, Diverticulitis | Early Phase 1 | Unknown | Thomas Jefferson University | 224 | 2016-09-01 | 2018-08-22 |
| Efficacy and Safety Study of Rifaximin Vaginal Tablets in Bacterial Vaginosis RIFAXIMIN VAGINAL TABLET 25 MG, RIFAXIMIN VAGINAL TABLET 100 MG, PLACEBO VAGINAL TABLET - BACTERIAL VAGINOSIS | Phase 2 | Terminated | Alfasigma S.p.A. | 392 | 2015-04-01 | 2016-10-10 |
| Effect of a Yoghurt Containing Four Probiotic Lactobacillus Strains on Bacterial Vaginosis probiotic yoghurt, chemically acidified milk, Arilin - Bacterial Vaginosis | Not applicable | Completed | Clinical Research Center Kiel GmbH | 36 | 2015-02-01 | 2016-11-17 |
| Impact of Oral Antibiotic Treatment on C. Difficile Fidaxomicin, Metronidazole, Vancomycin - C. Difficile, Diarrhea | Phase 4 | Completed | Duke University | 33 | 2014-06-10 | 2019-10-02 |
| Study to Determine the Equivalence of Three Products Containing Metronidazole Benzoate. Metronidazole benzoate, Flagyl 125 mg/5 ml oral suspension, Flagyl 400 mg Tablets - Bacterial Infections | Phase 1 | Completed | Verisfield UK Ltd. Greek Branch | 6 | 2014-06-01 | 2014-08-01 |
| Patients Response to Early Switch To Oral:Osteomyelitis Study oral antibiotics, intravenous antibiotics - Osteomyelitis | Early Phase 1 | Terminated | Julio Ramirez | 11 | 2014-03-06 | 2021-04-06 |
| Conservative Treatment of Acute Appendicitis in Children Appendectomy, Conservative, non-surgical treatment - Appendicitis, Child | Not applicable | Completed | Karolinska University Hospital | 51 | 2012-02-01 | 2012-10-17 |
| Safety, Tolerability and Efficacy of BFH772 in Rosacea Patients BFH772 1% ointment, Vehicle ointment, Noritate® 1% cream - Erythemato-telangiectatic Rosacea | Phase 2 | Completed | Novartis Pharmaceuticals | 36 | 2011-09-01 | 2021-02-21 |
| Antibiotic Prophylaxis in the Prevention of Surgical Site Infections After Selected Urgent Abdominal Surgical Procedures Metronidazole, Cefuroxime, Amoxicillin (+ clavulanic acid) and Fluconazole, Placebo - Acute Appendicitis, Perforated Gastroduodenal Ulcer | Phase 3 | Completed | The Faculty Hospital Na Bulovce | 187 | 2008-07-01 | 2012-02-08 |
| The Treatment of Periodontal Diseases Metronidazol - Digestive System Disorders, Adverse Effects | Phase 4 | Unknown | University of Oslo | 184 | 2008-01-01 | 2013-11-20 |
| Vaccine Therapy With PROSTVAC/TRICOM and Flutamide Versus Flutamide Alone to Treat Prostate Cancer Sargramostim (GM-CSF, Leukine), Flutamide (Eulexin), PROSTVAC-F/ TRICOM - Prostate Cancer | Phase 2 | Completed | National Cancer Institute (NCI) | 64 | 2007-02-23 | 2018-11-29 |
| Study of Conservative Versus Surgical Treatment of Appendicitis cefotaxim and metronidazol - Appendicitis | Phase 2 | Completed | Göteborg University | 360 | 2006-05-01 | 2009-04-21 |
| Bioequivalence of Metronidazole Gel, 0.75% in the Treatment of Bacterial Vaginosis Metronidazole - Bacterial Vaginosis | Phase 1 / Phase 2 | Completed | Teva Pharmaceuticals USA | 579 | 2002-01-01 | 2024-08-19 |
| Bioavailability of Metronidazole Vaginal Gel in Healthy Subjects Metronidazole - Healthy | Phase 1 | Completed | Teva Pharmaceuticals USA | 38 | 2001-11-01 | 2010-06-29 |
Vaginosis, Bacterial (4) · Appendicitis (3) · Colorectal Neoplasms (2) · Surgical Wound Infection (2) · Bacterial Infections (1) · Diarrhea (1) · Digestive System Diseases (1) · Diverticulitis (1) · Dry Socket (1) · Enterocolitis (1) · Infections (1) · Inflammatory Bowel Diseases (1) · Osteomyelitis (1) · Periodontitis (1) · Peritonsillar Abscess (1)
Teva Pharmaceuticals USA (2) · Alfasigma S.p.A. (1) · Clinical Research Center Kiel GmbH (1) · Dow University of Health Sciences (1) · Duke University (1) · Göteborg University (1) · I.M. Sechenov First Moscow State Medical University (1) · Johns Hopkins University (1) · Julio Ramirez (1) · Karolinska University Hospital (1) · M.D. Anderson Cancer Center (1) · National Cancer Institute (NCI) (1) · New York Medical College (1) · Novartis Pharmaceuticals (1) · Odense University Hospital (1)
United States (11) · Sweden (2) · Czechia (1) · Denmark (1) · Germany (1) · Jordan (1) · Norway (1) · Pakistan (1) · Russia (1)
Abdullah Hiyari, MD (1) · Benjamin Phillips, MD (1) · Christiane Laue, Dr. med. (1) · Daniel J Sexton, MD (1) · David Seligson, MD (1) · Hans R Preus, PhD (1) · Jan F Svensson, MD (1) · Julio Ramirez, MD (1) · Kent Lundholm (1) · Kseniya Rossolovskaya (1) · Leonid Spivak, MD,Prof. (1) · Michael J Overman (1) · Naji Najib, B.Sc. Pharm (1) · Ondrej Ryska, MD (1)
PMID 15276398, PMID 15840453, PMID 19358184, PMID 19588358, PMID 22530208, PMID 25072441, PMID 25981528, PMID 27767387, PMID 28796888, PMID 31603245, PMID 31800496, PMID 34017999, PMID 34790237, PMID 36748942, PMID 37134294, PMID 38596254, PMID 4902833, PMID 8948280
P50CA221707 (1)