879 completed, 309 unknown, 285 recruiting, 210 terminated. 491 Not applicable, 315 Phase 2, 238 Phase 3, 167 Phase 1, 151 Phase 4.
Follow Crohn Disease: new trials by email Literature Review of Crohn Disease trials Research Report on Crohn Disease
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| ACT for Veterans With IBD and Mental Health Challenges Acceptance and Commitment Therapy - Inflammatory Bowel Diseases, Crohn's Disease | Not applicable | Not yet recruiting | VA Office of Research and Development | 50 | 2028-01-01 | 2026-02-09 |
| Digital Mind Body Intervention Among Black and Hispanic Patients Living With Inflammatory Bowel Disease Digital Mind Body Intervention mobile application - Crohn's Disease, Ulcerative Colitis | Not applicable | Not yet recruiting | Montefiore Medical Center | 40 | 2027-07-01 | 2026-09-14 |
| Adapted Physical Activity for Persistent Fatigue in Patients With Inflammatory Bowel Disease in Remission Adapted Physical Activity, Usual Care - Inflammatory Bowel Diseases (IBD), Fatigue | Not applicable | Not yet recruiting | University Hospital, Grenoble | 120 | 2027-06-01 | 2026-09-11 |
| LMT503 First-in-human SAD, MAD, and FE Study LMT503, Placebo - Inflammatory Bowel Disease, Colitis, Ulcerative | Phase 1 | Not yet recruiting | Lmito Therapeutics Inc. | 72 | 2027-03-01 | 2026-09-01 |
| Efficacy and Safety of TRA16 Administered Orally in Patients With Enteric Hyperoxaluria (EH). TRA16, Placebo - Enteric Hyperoxaluria | Phase 2 | Not yet recruiting | Wuhan Kangfude Urolithiasis Research Institute Co., Ltd. | 30 | 2027-03-01 | 2026-10-13 |
| Oral N-acetylglucosamine in Crohn's Disease N-Acetylglucosamine (GlcNAc) - Crohns Disease | Phase 2 | Not yet recruiting | Johns Hopkins University | 40 | 2027-01-05 | 2026-11-05 |
| Intertriginous/Periorificial Dermatoses in Patients With IBD on Anti-TNFα: Relative Abundance of Staphylococcus Aureus Within the Lesion Microbiota and Clinical Correlation (micSPIDER). Inflammatory Bowel Diseases, Crohn's Disease | Not yet recruiting | Centre Hospitalier Universitaire de Nīmes | 82 | 2027-01-01 | 2026-11-13 | |
| The EDICT Trial - Therapy for Inflammatory Bowel Disease Flares elemental diet (ED) - Inflammatory Bowel Disease | Not applicable | Not yet recruiting | Wake Forest University Health Sciences | 42 | 2026-12-01 | 2026-09-28 |
| MIRICURE: Mirikizumab With Curettage and Repair (Closure) for Perianal Fistulizing Crohn's Disease Mirikizumab, Fistula Tract Curettage and Closure - Crohn's Disease, Perianal Fistula | Phase 4 | Not yet recruiting | Icahn School of Medicine at Mount Sinai | 50 | 2026-12-01 | 2026-08-24 |
| A Real-World Study of Guselkumab Persistence and Effectiveness in Participants With Crohn's Disease or Ulcerative Colitis Colitis, Ulcerative, Crohn Disease | Not yet recruiting | Janssen-Cilag, S.A. | 200 | 2026-11-15 | 2026-11-03 | |
| A Study of Continued Use of Guselkumab in Participants With Crohn's Disease and Ulcerative Colitis in Real World Setting Crohn Disease, Colitis, Ulcerative | Not yet recruiting | Janssen Sciences Ireland UC | 35 | 2026-11-12 | 2026-11-03 | |
| A Study of SL-325 in Crohn's Disease Patients SL-325, Placebo - Crohn's Disease | Phase 2 | Recruiting | Shattuck Labs, Inc. | 232 | 2026-11-09 | 2026-11-12 |
| Longitudinal Immunophenotyping of Patients With Inflammatory Bowel Disease Inflammatory Bowel Disease, Crohn's Disease | Recruiting | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | 100 | 2026-11-05 | 2026-11-10 | |
| An Open-label, DDI Study to Investigate the Effects of Duvakitug on the PK of Selected Cytochrome P450 Substrates Duvakitug - Ulcerative Colitis, Crohn's Disease | Phase 1 | Not yet recruiting | Sanofi | 25 | 2026-11-03 | 2026-11-06 |
| Partial Enteral Nutrition as Therapeutic Augmentation of Advanced Pharmacological Therapy in Patients With Active Crohn's Disease Partial enteral nutrition - orally consumed formula - Crohn's Disease, Active | Not applicable | Enrolling by invitation | James Lewis | 80 | 2026-11-03 | 2026-11-12 |
| Longitudinal Registry of Difficult-to-Treat Inflammatory Bowel Disease Routine IBD Management and Advanced-Therapy Exposure - Inflammatory Bowel Diseases (IBD), Crohn Disease | Not yet recruiting | First Affiliated Hospital, Sun Yat-Sen University | 2000 | 2026-11-01 | 2026-10-26 | |
| R-3750 in Patients With Crohn's Disease R-3750, Placebo - Crohn Disease (CD) | Phase 1 | Not yet recruiting | Rise Therapeutics LLC | 40 | 2026-11-01 | 2026-08-28 |
| Emerging Indications for Hyperbaric Oxygen Treatment Hyperbaric oxygen treatment (HBOT), 100% Oxygen - Post-COVID-19 Condition, Ulcerative Colitis | Phase 4 | Not yet recruiting | Jay C. Buckey Jr. | 100 | 2026-11-01 | 2026-09-09 |
| Artificial Intelligence For Outcomes Research in Crohn's Disease: Digital Pathology Assessment of Fibrosis and Association With Patient History and Clinical Outcomes Ph-FCS(Muc) fibrosis severity Digital Pathology biomarker - Crohn Disease, Fibrostenotic Crohn's Disease | Not yet recruiting | PharmaNest, Inc | 100 | 2026-11-01 | 2026-10-01 | |
| Validation and Clinical Impact of GLIM Criteria in Patients With Inflammatory Bowel Disease Inflammatory Bowel Diseases, Crohn Disease | Not yet recruiting | Assiut University | 210 | 2026-11-01 | 2026-10-22 |
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Colitis, Ulcerative (665) · Inflammatory Bowel Diseases (602) · Arthritis, Rheumatoid (68) · Arthritis, Psoriatic (46) · Spondylitis, Ankylosing (39) · Psoriasis (37) · Irritable Bowel Syndrome (32) · Inflammation (31) · Celiac Disease (25) · Colorectal Neoplasms (25) · Depression (23) · Fistula (23) · Intestinal Diseases (22) · Autoimmune Diseases (21)
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Infliximab (94) · Adalimumab (74) · Ustekinumab (53) · vedolizumab (49) · Azathioprine (34) · Certolizumab Pegol (33) · Fecal Microbiota Transplantation (24) · risankizumab (21) · Blood Specimen Collection (18) · Cholecalciferol (18) · guselkumab (18) · Endoscopy (17) · Colonoscopy (15) · upadacitinib (14) · CT-P13 (13)
Takeda (68) · AbbVie (46) · Sixth Affiliated Hospital, Sun Yat-sen University (33) · Janssen Research & Development, LLC (25) · Groupe d'Etude Therapeutique des Affections Inflammatoires Digestives (22) · Mayo Clinic (21) · Assistance Publique - Hôpitaux de Paris (19) · Central Hospital, Nancy, France (17) · Children's Hospital Medical Center, Cincinnati (15) · Jinling Hospital, China (15) · Merck Sharp & Dohme LLC (15) · Second Affiliated Hospital of Wenzhou Medical University (15) · Second Affiliated Hospital, Zhejiang University, School of Medicine (15) · UCB Pharma (15) · Abbott (14)
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