67 completed, 10 unknown, 5 recruiting, 4 terminated. 30 Not applicable, 24 Phase 2, 20 Phase 4, 19 Phase 3, 5 Phase 1.
Follow Zinc Sulfate: new trials by email Literature Review of Zinc Sulfate trials Research Report on Zinc Sulfate
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Comparative Study Evaluating Safety and Effectiveness of ( Proton Pump Inhibitor Versus Vonoprazan ) Based Triple Therapy With or Without Zinc to Eradicate H. Pylori Infection zinc sulfate, Vonoprazan + amoxicillin + clarithromycin, proton pump inhibitor + amoxicillin - HELICOBACTER PYLORI INFECTIONS | Phase 3 | Recruiting | Tanta University | 88 | 2026-02-01 | 2026-09-09 |
| Zinc Supplementation and Infections in Older Medical Patients Zinc (zinc sulphate) - Older Adults (65 Years and Older), Medical Patients in the Emergency Department | Not applicable | Recruiting | Herlev Hospital | 8000 | 2026-02-01 | 2026-05-29 |
| Comparison of Efficacy and Safety of Vita 6 Versus Zinc Along With Applied Behavioural Therapy Vita 6, Zinc sulfate - Autism Spectrum Disorder | Not applicable | Completed | Muhammad Aamir Latif | 64 | 2025-09-23 | 2026-04-15 |
| Zinc Sulphate in Treatment Fibrosis in HBV Patient Receiving Antiviral Therapy Entecavir (ETV), Zinc (zinc sulphate) - Liver Fibroses, HBV (Hepatitis B Virus) | Phase 2 | Not yet recruiting | Tanta University | 44 | 2025-09-01 | 2025-08-28 |
| COMPARISON OF ZINC AND PROBIOTICS ON NEONATES WITH INDIRECT HYPERBILIRUBINEMIA UNDERGOING PHOTOTHERAPY Zinc sulfate, Probiotic lactobacillus rhamnosus GG - Indirect Hyperbilirubinemia, Neonatal | Phase 2 | Recruiting | Quaid-e-Azam Medical College | 110 | 2025-08-07 | 2025-08-05 |
| Zinc for Infection Prevention in Sickle Cell Anemia-2 (ZIPS-2) zinc sulfate, Placebo - Sickle Cell Disease | Phase 2 / Phase 3 | Completed | Indiana University | 100 | 2025-02-10 | 2026-01-30 |
| Tralement Versus a Fixed-dose Trace Element Combination Product to Evaluate Manganese Safety Tralement, Fixed-dose trace element combination product of zinc, copper, and selenious acid - Manganese Safety in Adults | Phase 4 | Withdrawn | American Regent, Inc. | 2025-02-01 | 2025-02-12 | |
| Efficacy & Safety of Oral Adjuvants to Phototherapy in Neonatal Hyperbilirubinemia Zinc sulfate, Ursodeoxycholic acid - Neonatal Hyperbilirubinemia | Phase 4 | Completed | Amira Adel Fouly | 140 | 2024-09-01 | 2026-09-10 |
| Tralement vs. Fixed-dose Trace Element Combination Product in Patients >3 to 17 Years of Age Requiring Long-term PN Tralement, Fixed-dose trace element combination product of zinc, copper, and selenious acid - Manganese Safety in Pediatric Patients | Phase 4 | Withdrawn | American Regent, Inc. | 2024-08-01 | 2024-11-15 | |
| Effect of Zinc Supplementation on Hyperhomocysteinemia Compared to Folic Acid in CKD Patient on Hemodialysis Zinc Sulfate 50 Mg Tab, Folic Acid 5 Mg Oral Tablet - Chronic Kidney Disease Requiring Hemodialysis | Not applicable | Recruiting | Chittagong Medical College | 90 | 2024-07-01 | 2025-05-23 |
| Enteral Zinc Supplementation in Very Low Birth Weight Infants Zinc Sulfate, Sterile Water - Very Low Birth Weight Infant, Nutritional Deficiency | Phase 3 | Unknown | University of Tennessee | 50 | 2024-06-01 | 2024-06-06 |
| Efficacy Of Zinc Towards The Outcome on Children With Sepsis Zinc Sulfate, Placebo - Sepsis | Not applicable | Completed | dr. Aldora Jesslyn Oentari | 140 | 2024-02-01 | 2024-08-16 |
| Effect of Probiotic and Zinc Supplementations on the Clinical Outcome in Pediatric Patients with Ventriculitis Probiotic Formula, Zinc - Ventriculitis, Infectious | Phase 4 | Recruiting | Ain Shams University | 140 | 2023-07-01 | 2025-02-25 |
| Effect of N-acetyl Cysteine and Zinc in Management of Head and Neck Cancer Radiotherapy Induced Oral Mucositis N-acetyl cysteine, Zinc sulfate, saline mouth wash - Radiation-Induced Mucositis | Phase 2 | Completed | Mansoura University | 50 | 2023-06-28 | 2024-12-31 |
| Effect of Pentoxifylline and Zinc Co-administration in Patients With Oligoasthenoteratozoospermia Placebo, Pentoxifylline, zinc - Idiopathic Infertility | Not applicable | Unknown | Arak University of Medical Sciences | 140 | 2022-01-01 | 2022-01-03 |
| Effect of Oral Zinc Sulfate on Jaundice in Neonates Admitted to Neonatal Intensive Care Unit Zinc sulfate, Placebo, Phototherapy - Serum Bilirubin | Not applicable | Completed | Makassed General Hospital | 60 | 2021-12-17 | 2022-08-30 |
| Effectiveness of Zinc Supplementation in Management of Patients With Symptomatic Benign Migratory Glossitis Zinc Sulfate 110 MG (Zinc 25 MG) Oral Tablet - Benign Migratory Glossitis | Phase 4 | Completed | mariam hamouda | 48 | 2021-09-06 | 2023-08-01 |
| EFFECTIVENESS OF ZINC AS AN ADJUVANT TO STANDARD THERAPY VERSUS STANDARD THERAPY ALONE IN CHILDREN zinc sulphate - Asthma in Children | Phase 3 | Completed | King Edward Medical University | 84 | 2021-09-01 | 2025-03-26 |
| The Therapeutic Effect of Co-administration of Pentoxifylline and Zinc in Men With Idiopathic Asthenozoospermia Zinc Sulfate 220 mg Capsules, Pentoxifylline - Men Infertility | Early Phase 1 | Unknown | Arak University of Medical Sciences | 160 | 2021-08-01 | 2022-01-05 |
| Study to Assess the Effect of Zinc in Atorvastatin Treated Hyperlipidemic Patients Zinc sulfate, Placebo - Hyperlipidemias | Phase 2 | Unknown | Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh | 92 | 2021-05-01 | 2022-05-27 |
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Diarrhea (9) · Asthenozoospermia (5) · Pneumonia (5) · Anemia, Sickle Cell (3) · COVID-19 (3) · Coronavirus Infections (3) · Sepsis (3) · Thalassemia (3) · Critical Illness (2) · Dysgeusia (2) · Infections (2) · Malnutrition (2) · Acne Vulgaris (1) · Alcoholism (1) · Anemia (1)
Ain Shams University (4) · International Centre for Diarrhoeal Disease Research, Bangladesh (4) · Babylon University (3) · Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh (3) · Centre For International Health (3) · Fakultas Kedokteran Universitas Indonesia (3) · University of California, Davis (3) · Aga Khan University (2) · American Regent, Inc. (2) · Arak University of Medical Sciences (2) · Cairo University (2) · Mansoura University (2) · St. Francis Hospital, New York (2) · Swiss Federal Institute of Technology (2) · Tanta University (2)
United States (16) · Egypt (12) · Bangladesh (8) · Pakistan (7) · Iraq (5) · Iran (4) · Indonesia (3) · Mexico (3) · India (2) · Senegal (2) · Switzerland (2) · Bolivia (1) · Brazil (1) · Colombia (1) · Denmark (1)
Kenneth H Brown, MD (3) · Avni Thakore, MD (2) · Halvor Sommerfelt, MD, PhD (2) · Lamia A. Almashhedy, PhD (2) · Tor A Strand, MD, PhD (2) · Abdul Razzaq A. Alsalman, PhD (1) · Abdulrrazaq S. Alsalman, PhD (1) · Abdulsamie H Alta'ee, PhD (1) · Ahmed E Shouman, Professor (1) · Ahmed F Mahmoud Hussein, MS.c (1) · Alan R Shuldiner, MD (1) · Aldora Jesslyn Oentari (1) · Alsalman Abdulrrazaq, PhD (1) · Aminah Jatoi, MD (1)
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1KL2RR025006-01 (1), IK2CX000643 (1), K23AA018399 (1), K23HL076468 (1), K23HL105654 (1), P30CA138292 (1), U01AA021893 (1)