5 completed, 3 terminated, 3 unknown, 2 recruiting. 15 Phase 3, 4 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 15 | Completed 5, Terminated 3, Unknown 3, Recruiting 2, Not yet recruiting 1, Withdrawn 1 |
| Phase 2 | 4 | Unknown 2, Completed 1, Not yet recruiting 1 |
Follow Constriction, Pathologic: new trials by email Literature Review of Constriction, Pathologic trials Research Report on Constriction, Pathologic
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Adjuvant Steroid Outcomes in Idiopathic Subglottic Stenosis Triamcinolone 0.1%, Placebo - Idiopathic Subglottic Stenosis | Phase 3 | Recruiting | Johns Hopkins University | 226 | 2026-05-20 | 2026-10-22 |
| A Study Comparing the MAGICTouch™ Sirolimus-coated Balloon With a Paclitaxel-coated Balloon for Treating Severe Narrowing or Blockage in the Femoropopliteal Arteries. Sirolimus (RAPAMUNE) drug-coated balloon angioplasty catheter, Paclitaxel drug-coated balloon angioplasty - Popliteal Artery Disease, Superficial Femoral Artery Disease | Phase 2 / Phase 3 | Not yet recruiting | Concept Medical Inc. | 478 | 2026-04-01 | 2026-04-17 |
| Anticoagulation Using Rivaroxaban on Top of Aspirin in Intracranial Atherosclerotic Stenosis Rivaroxaban, Clopidogrel, Aspirin - Ischemic Stroke, Intracranial Atherosclerosis | Phase 2 / Phase 3 | Unknown | The First Affiliated Hospital with Nanjing Medical University | 1180 | 2023-12-30 | 2023-12-21 |
| Extra Alirocumab in Addition to Statin Therapy in Asymptomatic Intracranial Atherosclerotic Stenosis (EAST-aICAS) Alirocumab, Atorvastatin - Intracranial Atherosclerosis, Atherosclerotic Plaque | Phase 3 | Unknown | The First Affiliated Hospital with Nanjing Medical University | 80 | 2023-12-30 | 2023-12-21 |
| Paclitaxel Coated Balloon for the Treatment of Chronic bEnigN sTricture- Bowel GIE Medical ProTractX3 TTS DCB, Control - Bowel; Stricture | Phase 3 | Recruiting | GIE Medical | 171 | 2023-11-01 | 2025-06-25 |
| Impact of Local Steroid Application in Extreme Lateral Lumbar Interbody Fusion Methylprednisolone, Saline - Stenosis, Herniated Nucleus Pulposus | Phase 3 | Withdrawn | Rush University Medical Center | 2018-05-22 | 2020-11-20 | |
| Colchicine to Prevent Post-Pericardiotomy Syndrome and Atrial Fibrillation Colchicine, Placebo - Atrial Fibrillation, Post-pericardiotomy Syndrome | Phase 3 | Terminated | Mayo Clinic | 2 | 2015-05-01 | 2017-06-21 |
| Clinical Trial on Peripheral Arteries Treated With SeQuent® Please P Paclitaxel Coated Balloon Catheter Paclitaxel coated balloon, uncoated PTA catheter - Stenosis, Restenosis | Phase 3 | Completed | B. Braun Melsungen AG | 153 | 2013-10-01 | 2020-03-30 |
| Comparison of Endoscopic Radiofrequency Ablation Versus Photodynamic Therapy for Inoperable Cholangiocarcinoma Self expanding metallic stent (SEMS), Endoscopic radiofrequency ablation (ERFA), Photodynamic therapy (PDT) - Cholangiocarcinoma | Phase 2 / Phase 3 | Unknown | Guangzhou Medical University | 120 | 2012-11-01 | 2013-02-26 |
| ViVEXX Carotid Revascularization Trial (VIVA) Carotid Artery Stenting - Carotid Artery Stenosis | Phase 3 | Completed | C. R. Bard | 407 | 2005-10-01 | 2017-03-01 |
| BBC ONE - British Bifurcation Coronary Study Coronary Angioplasty - Ischaemic Heart Diseases, Stenosis | Phase 3 | Completed | Royal Sussex County Hospital | 500 | 2005-01-01 | 2008-04-16 |
| Abciximab for Prevention of Stroke Recurrence Before Endarterectomy in Symptomatic Carotid Stenosis Abciximab - Stroke, Stenosis | Phase 3 | Terminated | University of Zurich | 100 | 2004-04-01 | 2007-05-03 |
| Magnevist® Injection Enhanced MRA Compared to Non Contrast MRA for the Detection of Stenosis in the Calf and/or Pedal Arteries Gadopentetate dimeglumine (Magnevist) - Stenosis | Phase 3 | Completed | Bayer | 126 | 2003-12-01 | 2014-12-30 |
| Randomized Trial Evaluating Slow-Release Formulation TAXUS Paclitaxel-Eluting Coronary Stents to Treat De Novo Coronary Lesions TAXUS Paclitaxel-Eluting Coronary Stent, Slow-Formulation, Express2 - Coronary Stenosis | Phase 2 / Phase 3 | Completed | Boston Scientific Corporation | 1108 | 2003-02-01 | 2010-08-06 |
| Aspirin Or Warfarin To Prevent Stroke Warfarin, Aspirin - Stroke, Cerebral Infarction | Phase 3 | Terminated | National Institute of Neurological Disorders and Stroke (NINDS) | 2006-06-06 |
Stroke (3) · Carotid Stenosis (2) · Intracranial Arteriosclerosis (2) · Ischemic Stroke (2) · Adenocarcinoma (1) · Angina Pectoris (1) · Atherosclerosis (1) · Atrial Fibrillation (1) · Bile Duct Diseases (1) · Biliary Tract Diseases (1) · Bites and Stings (1) · Carcinoma (1) · Cerebral Infarction (1) · Cholangiocarcinoma (1)
Pathological Conditions, Anatomical (15) · Pathological Conditions, Signs and Symptoms (15) · Cardiovascular Diseases (9) · Vascular Diseases (8) · Arterial Occlusive Diseases (7) · Nervous System Diseases (7) · Central Nervous System Diseases (6) · Arteriosclerosis (5) · Brain Diseases (5) · Cerebrovascular Disorders (5) · Heart Diseases (3) · Carotid Artery Diseases (2) · Coronary Disease (2) · Intracranial Arterial Diseases (2) · Myocardial Ischemia (2)
Aspirin (2) · Abciximab (1) · Angioplasty, Balloon (1) · Atorvastatin (1) · Clopidogrel (1) · Colchicine (1) · Gadolinium DTPA (1) · Methylprednisolone (1) · Photochemotherapy (1) · Rivaroxaban (1) · Sirolimus (1) · Sodium Chloride (1) · Warfarin (1) · alirocumab (1)
The First Affiliated Hospital with Nanjing Medical University (2) · B. Braun Melsungen AG (1) · Bayer (1) · Boston Scientific Corporation (1) · C. R. Bard (1) · Concept Medical Inc. (1) · GIE Medical (1) · Guangzhou Medical University (1) · Johns Hopkins University (1) · Mayo Clinic (1) · National Institute of Neurological Disorders and Stroke (NINDS) (1) · Royal Sussex County Hospital (1) · Rush University Medical Center (1) · University of Zurich (1)
United States (6) · China (2) · Germany (1) · Switzerland (1) · United Kingdom (1)
Alexander Hillel, MD (1) · Brain DeRubertis, MD (1) · David J.R, Hildick-Smith, MD (1) · Edward Choke, PhD (1) · Eric A Secemsky, MD (1) · Farhana Siddique (1) · Gregg W. Stone, MD (1) · Jae Oh, MD (1) · Kenneth Rosenfield, MD (1) · Kern Singh, MD (1) · Kezhong Zhang, Doctor (1) · Kezhong Zhang, MD (1) · Marc Chimowitz (1) · Masahiko Fujihara, MD (1)
PMID 16160130, PMID 20129555, PMID 20194880, PMID 21205942, PMID 22496083, PMID 27161619, PMID 28660441, PMID 29589098, PMID 39182330, PMID 42573020
1UG3HL173394-01A1 (1)