1044 completed, 417 unknown, 325 recruiting, 146 terminated. 634 Not applicable, 583 Phase 2, 270 Phase 1, 199 Phase 3, 104 Phase 4.
Follow Biliary Tract Diseases: new trials by email Literature Review of Biliary Tract Diseases trials Research Report on Biliary Tract Diseases
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| ESP vs Subcostal TAP Block for Analgesia After Laparoscopic Cholecystectomy Erector Spinae Plane Block, Subcostal Transversus Abdominis Plane Block - Cholelithiasis, Postoperative Pain, Laparoscopic Cholecystectomy | Not applicable | Not yet recruiting | Gaziantep City Hospital | 100 | 2027-06-15 | 2026-06-22 |
| Multicenter Phase 2 Study of Envafolimab in Biliary Tract Cancers Envafolimab plus Gemcitabine&Cisplatin, Gemcitabine&Cisplatin - Biliary Tract Neoplasms | Phase 2 | Not yet recruiting | 3D Medicines (Sichuan) Co., Ltd. | 126 | 2027-06-01 | 2026-03-25 |
| Two Bupivacaine Concentrations for Recto-Intercostal Fascial Plane Block After Laparoscopic Cholecystectomy Bupivacaine 0.25% - recto-intercostal fascial plane block, Bupivacaine 0.125% - recto-intercostal fascial plane block, Bupivacaine 0.25% - port-site infiltration - Postoperative Pain, Acute Pain | Not applicable | Not yet recruiting | Medipol University | 90 | 2027-01-30 | 2026-10-29 |
| Investigating Precision Medicine in the Adjuvant Setting in Biliary Tract Cancer Futibatinib, Ivosidenib + Capecitabine, Zanidatamab + Capecitabine - Biliary Tract Cancer (BTC) | Phase 3 | Not yet recruiting | UNICANCER | 990 | 2027-01-02 | 2026-08-04 |
| TRANScriptional Pathways Of Surgical Pain Modulated by Music Therapy Exposure (TRANSPOSE) Music-assisted relaxation and imagery (MARI) - Surgery, Stomach Cancer | Not applicable | Not yet recruiting | Case Comprehensive Cancer Center | 20 | 2027-01-01 | 2026-08-05 |
| Acute Cholecystitis Biliary Complications - ICG ICG - Acute Cholecystitis, Biliary Complications | Not applicable | Not yet recruiting | Hospital del Mar | 296 | 2027-01-01 | 2026-03-19 |
| SnapChole: An International, Time-Bound Prospective Platform Study of Management Strategies and Outcomes in Acute Calculous Cholecystitis Cholecystitis, Acute | Not yet recruiting | European Society for Trauma and Emergency Surgery | 1500 | 2027-01-01 | 2026-10-01 | |
| Daraxonrasib in Asian RAS-mutant Biliary Tract Cancer Daraxonrasib - Biliary Tract Cancer (BTC) | Phase 2 | Not yet recruiting | National Health Research Institutes, Taiwan | 55 | 2027-01-01 | 2026-11-02 |
| FEAST and HOPE: Redox PSC Pilot Study N-Acetyl Cysteine (NAC), Alpha-Lipoic Acid (ALA), Nicotinamide Riboside (NR) - Primary Sclerosing Cholangitis (PSC) | Phase 2 | Not yet recruiting | Brigham and Women's Hospital | 15 | 2027-01-01 | 2026-10-27 |
| Study of ACC-1898 in Adult Participants With Advanced Solid Tumors ACC-1898 - Hepatocellular Carcinoma, Renal Cell Carcinoma | Phase 1 | Not yet recruiting | AccSalus Biosciences, Inc. | 40 | 2027-01-01 | 2026-10-28 |
| Scheduled Meditation for Improving Postoperative Outcomes in Patients Undergoing Pancreatectomy Actigraphy, Online Mindfulness Meditation, Smartphone Application-based Intervention - Hepatocellular Carcinoma, Pancreas Cancer | Not applicable | Not yet recruiting | City of Hope Medical Center | 70 | 2027-01-01 | 2026-11-10 |
| Zanidatamab Combined With Liposomal Irinotecan and Capecitabine for Second-line Treatment of HER2-positive Unresectable Biliary Tract Tumors Zanidatamab - Biliary Tract Cancer | Phase 2 | Not yet recruiting | Anhui Provincial Hospital | 15 | 2026-11-30 | 2026-10-01 |
| Hepatic Arterial Infusion Chemotherapy Versus Capecitabine as Adjuvant Therapy for Resected Biliary Tract Cancer Oxaliplatin, 5-Fluorouracil, Capecitabine - Biliary Tract Cancer, Cholangiocarcinoma | Phase 3 | Not yet recruiting | Zhai Wenlong | 90 | 2026-11-30 | 2026-11-04 |
| Research on Construction and Verification of Multimodal Medical Imaging Large Model Liver Diseases, Gallbladder Diseases | Not yet recruiting | Second Affiliated Hospital, Zhejiang University, School of Medicine | 2000 | 2026-11-15 | 2026-03-03 | |
| Supraglottic Oxygenation Via Oral Transtracheal Catheter for Reducing the Incidence of Hypoxemia During ERCP Under Sedation The Supraglottic Oxygenation Via Oral Transtracheal Catheter Group, The Regular Nasal Cannula - Choledocholithiasis With Cholecystitis With Obstruction, Obstructive Jaundice | Not applicable | Not yet recruiting | Zhejiang University | 410 | 2026-11-12 | 2026-09-25 |
| Tucatinib Continuation Study tucatinib - HER2-positive Breast Cancer, Cervical Cancer | Phase 4 | Not yet recruiting | Pfizer | 175 | 2026-11-06 | 2026-08-28 |
| Percutaneous Drainage Versus EUS-guided Gallbladder Drainage in Poor Surgical Patients With Cholecystitis Endoscopic ultrasound guided gallbladder drainage (EUS-GBD) with lumen apposing metal stents (LAMS), Percutaneous gallbladder drainage - Cholecystitis, Acute | Not applicable | Recruiting | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | 212 | 2026-11-03 | 2026-11-12 |
| A Study of Fatigue, Itching and Daily Activities in People With Primary Biliary Cholangitis Starting Elafibranor Elafibranor - Primary Biliary Cholangitis (PBC) | Not yet recruiting | Ipsen | 50 | 2026-11-02 | 2026-10-30 | |
| Effects of Postoperative Video-assisted Early Mobilization on Recovery Outcomes Video-Assisted Early Mobilization Training - Cholelithiasis | Not applicable | Not yet recruiting | Muş Alparslan University | 44 | 2026-11-01 | 2026-10-13 |
| Effect of Labetalol, Magnesium Sulfate, or Lidocaine on Opioid Consumption During Laparoscopic Cholecystectomy Labetalol, Magnesium Sulfate, Lidocaine - Postoperative Pain, Cholelithiasis | Phase 4 | Not yet recruiting | Assiut University | 90 | 2026-11-01 | 2026-10-08 |
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Biliary Tract Neoplasms (484) · Gallbladder Neoplasms (296) · Bile Duct Neoplasms (251) · Pancreatic Neoplasms (246) · Cholangiocarcinoma (239) · Liver Cirrhosis, Biliary (214) · Gallstones (190) · Cholelithiasis (183) · Cholecystitis (175) · Stomach Neoplasms (152) · Cholangitis, Sclerosing (147) · Cholecystitis, Acute (138) · Cholestasis (138) · Carcinoma, Hepatocellular (109) · Choledocholithiasis (108)
Digestive System Diseases (2235) · Bile Duct Diseases (998) · Neoplasms by Site (901) · Digestive System Neoplasms (890) · Neoplasms (874) · Gallbladder Diseases (752) · Pathological Conditions, Signs and Symptoms (733) · Pathologic Processes (477) · Liver Diseases (439) · Neoplasms by Histologic Type (410) · Neoplasms, Glandular and Epithelial (388) · Biliary Tract Neoplasms (369) · Carcinoma (364) · Adenocarcinoma (343)
Gemcitabine (165) · Cisplatin (112) · Cholecystectomy, Laparoscopic (77) · Capecitabine (70) · Oxaliplatin (62) · Fluorouracil (51) · Cholangiopancreatography, Endoscopic Retrograde (45) · Ursodeoxycholic Acid (44) · Leucovorin (40) · durvalumab (39) · pembrolizumab (39) · Cholecystectomy (33) · Irinotecan (26) · fish oil triglycerides (23) · 130-nm albumin-bound paclitaxel (22)
National Cancer Institute (NCI) (40) · Mayo Clinic (30) · Assiut University (24) · Mirum Pharmaceuticals, Inc. (24) · Peking Union Medical College Hospital (22) · Seoul National University Hospital (20) · AstraZeneca (19) · Gilead Sciences (17) · Karolinska Institutet (15) · Hepatopancreatobiliary Surgery Institute of Gansu Province (14) · Intercept Pharmaceuticals (14) · Xijing Hospital of Digestive Diseases (14) · Yonsei University (14) · Ipsen (13) · RenJi Hospital (13)
United States (676) · China (412) · South Korea (197) · United Kingdom (156) · France (144) · Italy (141) · Germany (139) · Spain (137) · Canada (131) · Turkey (Türkiye) (94) · Japan (83) · Australia (76) · Belgium (75) · Egypt (67) · Taiwan (67)
Michel Kahaleh, MD (9) · Ed Doo, MD (8) · Lisa Henn, PhD (6) · John Magee, MD (5) · Katrina Loh, MD (5) · Li Yang, MD (5) · Tim F Greten, M.D. (5) · Hiroaki Nagano, MD, PhD (4)
PMID 20375404, PMID 21910897, PMID 25543678, PMID 37121331, PMID 33198671, PMID 37069476, PMID 38661512, PMID 38780109, PMID 42002216, PMID 17509029, PMID 17704863, PMID 1858735, PMID 19286178, PMID 19376789, PMID 19670912, PMID 20211892, PMID 2070995, PMID 22872303, PMID 23054338, PMID 23612857, PMID 24022431, PMID 24146220, PMID 24867013, PMID 25005650, PMID 25477010, PMID 26179201, PMID 26186803, PMID 26561627, PMID 26725209, PMID 27546389, PMID 27741006, PMID 28249726, PMID 28818953, PMID 28941329, PMID 29433850, PMID 29519540, PMID 29533266, PMID 29610513, PMID 29847616, PMID 29954008, PMID 29961772, PMID 30420614, PMID 30642373, PMID 30979521, PMID 30998813, PMID 31863440, PMID 32059815, PMID 32461347, PMID 32633158, PMID 32707155
2023 (21), 2016 (11), 2015 (10), 2019 (9), U01DK062456 (7), 2014 (6), 2025 (6), 2017 (5), 2018 (5), P30CA015083 (5), U01DK062436 (5), U01DK062445 (5), U01DK062452 (5), U01DK062453 (5), U01DK062466 (5)