1035 completed, 419 unknown, 324 recruiting, 145 terminated. 631 Not applicable, 578 Phase 2, 270 Phase 1, 197 Phase 3, 101 Phase 4.
Follow Biliary Tract Diseases: new trials by email Literature Review of Biliary Tract Diseases trials Research Report on Biliary Tract Diseases
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| ESP vs Subcostal TAP Block for Analgesia After Laparoscopic Cholecystectomy Erector Spinae Plane Block, Subcostal Transversus Abdominis Plane Block - Cholelithiasis, Postoperative Pain, Laparoscopic Cholecystectomy | Not applicable | Not yet recruiting | Gaziantep City Hospital | 100 | 2027-06-15 | 2026-06-22 |
| Multicenter Phase 2 Study of Envafolimab in Biliary Tract Cancers Envafolimab plus Gemcitabine&Cisplatin, Gemcitabine&Cisplatin - Biliary Tract Neoplasms | Phase 2 | Not yet recruiting | 3D Medicines (Sichuan) Co., Ltd. | 126 | 2027-06-01 | 2026-03-25 |
| Investigating Precision Medicine in the Adjuvant Setting in Biliary Tract Cancer Futibatinib, Ivosidenib + Capecitabine, Zanidatamab + Capecitabine - Biliary Tract Cancer (BTC) | Phase 3 | Not yet recruiting | UNICANCER | 990 | 2027-01-02 | 2026-08-04 |
| TRANScriptional Pathways Of Surgical Pain Modulated by Music Therapy Exposure (TRANSPOSE) Music-assisted relaxation and imagery (MARI) - Surgery, Stomach Cancer | Not applicable | Not yet recruiting | Case Comprehensive Cancer Center | 20 | 2027-01-01 | 2026-08-05 |
| Acute Cholecystitis Biliary Complications - ICG ICG - Acute Cholecystitis, Biliary Complications | Not applicable | Not yet recruiting | Hospital del Mar | 296 | 2027-01-01 | 2026-03-19 |
| SnapChole: An International, Time-Bound Prospective Platform Study of Management Strategies and Outcomes in Acute Calculous Cholecystitis Cholecystitis, Acute | Not yet recruiting | European Society for Trauma and Emergency Surgery | 1500 | 2027-01-01 | 2026-10-01 | |
| Zanidatamab Combined With Liposomal Irinotecan and Capecitabine for Second-line Treatment of HER2-positive Unresectable Biliary Tract Tumors Zanidatamab - Biliary Tract Cancer | Phase 2 | Not yet recruiting | Anhui Provincial Hospital | 15 | 2026-11-30 | 2026-10-01 |
| Research on Construction and Verification of Multimodal Medical Imaging Large Model Liver Diseases, Gallbladder Diseases | Not yet recruiting | Second Affiliated Hospital, Zhejiang University, School of Medicine | 2000 | 2026-11-15 | 2026-03-03 | |
| Supraglottic Oxygenation Via Oral Transtracheal Catheter for Reducing the Incidence of Hypoxemia During ERCP Under Sedation The Supraglottic Oxygenation Via Oral Transtracheal Catheter Group, The Regular Nasal Cannula - Choledocholithiasis With Cholecystitis With Obstruction, Obstructive Jaundice | Not applicable | Not yet recruiting | Zhejiang University | 410 | 2026-11-12 | 2026-09-25 |
| Tucatinib Continuation Study tucatinib - HER2-positive Breast Cancer, Cervical Cancer | Phase 4 | Not yet recruiting | Pfizer | 175 | 2026-11-06 | 2026-08-28 |
| Effects of Postoperative Video-assisted Early Mobilization on Recovery Outcomes Video-Assisted Early Mobilization Training - Cholelithiasis | Not applicable | Not yet recruiting | Muş Alparslan University | 44 | 2026-11-01 | 2026-10-13 |
| Effect of Labetalol, Magnesium Sulfate, or Lidocaine on Opioid Consumption During Laparoscopic Cholecystectomy Labetalol, Magnesium Sulfate, Lidocaine - Postoperative Pain, Cholelithiasis | Phase 4 | Not yet recruiting | Assiut University | 90 | 2026-11-01 | 2026-10-08 |
| Nemolizumab for the Treatment of Moderate to Severe Chronic Hepatic Pruritus Nemolizumab-ilto - Chronic Hepatic Pruritus, Cholestatic Liver Disease | Phase 2 | Not yet recruiting | Mayo Clinic | 15 | 2026-11-01 | 2026-09-28 |
| Phase 2 Study of Daraxonrasib in Recurrent KRAS-Mutant Biliary Tract Cancer Daraxonrasib - Biliary Tract Cancers, Intrahepatic Cholangiocarcinoma (Icc) | Phase 2 | Not yet recruiting | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | 55 | 2026-11-01 | 2026-08-28 |
| Alternating Chemo-immunotherapy and FGFR Inhibitor for FGFR-positive Biliary or Cholangiocarcinoma Biospecimen Collection, Cisplatin, Computed Tomography - Locally Advanced Ampulla of Vater Carcinoma, Locally Advanced Biliary Tract Carcinoma | Phase 2 | Recruiting | Ohio State University Comprehensive Cancer Center | 29 | 2026-11-01 | 2026-09-10 |
| IKS04 Regimen in Advanced Solid Tumors That Express CA242 IKS04 antibody drug conjugate ADC + Isumab04 monoclonal antibody - Colorectal Cancer, Gastro Esophageal Junctional Cancer | Phase 1 | Not yet recruiting | Iksuda Therapeutics Ltd. | 120 | 2026-11-01 | 2026-07-31 |
| Electrosurgical Patterns and Learning Curve in Elective Laparoscopic Cholecystectomy Elective laparoscopic cholecystectomy - Cholelithiasis | Recruiting | University Hospital of Split | 165 | 2026-10-15 | 2026-10-22 | |
| J-LINX: Japan LINerixibat eXtension Study Linerixibat - Pruritus | Phase 3 | Not yet recruiting | GlaxoSmithKline | 40 | 2026-10-09 | 2026-10-06 |
| Two Bupivacaine Concentrations for Rectus Intercostal Fascial Plane Block After Laparoscopic Cholecystectomy Bupivacaine 0.25% - rectus intercostal fascial plane block, Bupivacaine 0.125% - rectus intercostal fascial plane block, Bupivacaine 0.25% - port-site infiltration - Postoperative Pain, Acute Pain | Not applicable | Not yet recruiting | Medipol University | 90 | 2026-10-05 | 2026-10-05 |
| SumMET: Study of [225Ac]Ac-FL-261 in Participants With Solid Tumors Overexpressing c-MET [225Ac]Ac-FL-261 - Solid Tumor, NSCLC | Phase 1 / Phase 2 | Recruiting | Full-Life Technologies UK Limited | 208 | 2026-10-01 | 2026-10-16 |
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Biliary Tract Neoplasms (479) · Gallbladder Neoplasms (295) · Bile Duct Neoplasms (251) · Pancreatic Neoplasms (246) · Cholangiocarcinoma (238) · Liver Cirrhosis, Biliary (212) · Gallstones (188) · Cholelithiasis (181) · Cholecystitis (175) · Stomach Neoplasms (152) · Cholangitis, Sclerosing (146) · Cholecystitis, Acute (138) · Cholestasis (138) · Carcinoma, Hepatocellular (109) · Choledocholithiasis (107)
Digestive System Diseases (2219) · Bile Duct Diseases (991) · Neoplasms by Site (896) · Digestive System Neoplasms (885) · Neoplasms (869) · Gallbladder Diseases (748) · Pathological Conditions, Signs and Symptoms (725) · Pathologic Processes (470) · Liver Diseases (437) · Neoplasms by Histologic Type (408) · Neoplasms, Glandular and Epithelial (386) · Biliary Tract Neoplasms (369) · Carcinoma (362) · Adenocarcinoma (342)
Gemcitabine (165) · Cisplatin (112) · Cholecystectomy, Laparoscopic (77) · Capecitabine (68) · Oxaliplatin (61) · Fluorouracil (50) · Cholangiopancreatography, Endoscopic Retrograde (45) · Ursodeoxycholic Acid (43) · Leucovorin (40) · durvalumab (39) · pembrolizumab (39) · Cholecystectomy (33) · Irinotecan (26) · fish oil triglycerides (23) · 130-nm albumin-bound paclitaxel (22)
National Cancer Institute (NCI) (40) · Mayo Clinic (30) · Mirum Pharmaceuticals, Inc. (24) · Assiut University (22) · Peking Union Medical College Hospital (22) · Seoul National University Hospital (20) · AstraZeneca (19) · Gilead Sciences (17) · Karolinska Institutet (15) · Hepatopancreatobiliary Surgery Institute of Gansu Province (14) · Intercept Pharmaceuticals (14) · Xijing Hospital of Digestive Diseases (14) · Yonsei University (14) · RenJi Hospital (13) · Stanford University (13)
United States (673) · China (406) · South Korea (197) · United Kingdom (156) · France (143) · Italy (140) · Germany (138) · Spain (136) · Canada (131) · Turkey (Türkiye) (94) · Japan (83) · Australia (77) · Belgium (74) · Taiwan (66) · Egypt (65)
Michel Kahaleh, MD (9) · Ed Doo, MD (8) · Lisa Henn, PhD (6) · John Magee, MD (5) · Katrina Loh, MD (5) · Li Yang, MD (5) · Tim F Greten, M.D. (5) · Hiroaki Nagano, MD, PhD (4)
PMID 20375404, PMID 21910897, PMID 25543678, PMID 37121331, PMID 33198671, PMID 37069476, PMID 38661512, PMID 38780109, PMID 42002216, PMID 17509029, PMID 17704863, PMID 1858735, PMID 19286178, PMID 19376789, PMID 19670912, PMID 20211892, PMID 2070995, PMID 22872303, PMID 23054338, PMID 23612857, PMID 24022431, PMID 24146220, PMID 24867013, PMID 25005650, PMID 25477010, PMID 26179201, PMID 26186803, PMID 26561627, PMID 26725209, PMID 27546389, PMID 27741006, PMID 28249726, PMID 28818953, PMID 28941329, PMID 29433850, PMID 29519540, PMID 29533266, PMID 29610513, PMID 29847616, PMID 29954008, PMID 29961772, PMID 30420614, PMID 30642373, PMID 30979521, PMID 30998813, PMID 31863440, PMID 32059815, PMID 32461347, PMID 32633158, PMID 32707155
2023 (21), 2016 (11), 2015 (10), 2019 (9), U01DK062456 (7), 2014 (6), 2025 (6), 2017 (5), 2018 (5), P30CA015083 (5), U01DK062436 (5), U01DK062445 (5), U01DK062452 (5), U01DK062453 (5), U01DK062466 (5)