5 completed, 4 unknown, 3 not yet recruiting, 2 terminated. 15 Phase 2, 4 Phase 1, 4 Phase 3.
Follow Constriction, Pathologic: new trials by email Literature Review of Constriction, Pathologic trials Research Report on Constriction, Pathologic
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| FGF-1 for Intramuscular Injection for the Treatment of Peripheral Arterial Disease FGF-1, Placebo - Peripheral Arterial Disease, Stenosis | Phase 1 / Phase 2 | Not yet recruiting | Venturis Therapeutics, Inc. | 24 | 2028-10-15 | 2026-08-19 |
| A Phase 2, Placebo-Controlled Study of Oral RXC008 for Crohn's Strictures High Dose, Low Dose, Placebo - Strictures Due to Crohn's Disease | Phase 2 | Not yet recruiting | Redx Pharma Ltd | 180 | 2026-10-01 | 2026-09-22 |
| A Study Comparing the MAGICTouch™ Sirolimus-coated Balloon With a Paclitaxel-coated Balloon for Treating Severe Narrowing or Blockage in the Femoropopliteal Arteries. Sirolimus (RAPAMUNE) drug-coated balloon angioplasty catheter, Paclitaxel drug-coated balloon angioplasty - Popliteal Artery Disease, Superficial Femoral Artery Disease | Phase 2 / Phase 3 | Not yet recruiting | Concept Medical Inc. | 478 | 2026-04-01 | 2026-04-17 |
| COffee and Metabolites Modulating the Gut MicrobiomE in Colorectal caNCER Nestlé NESCAFÉ® TASTER'S CHOICE® House Blend capsule., Placebo - Colorectal Cancer, Coffee | Phase 1 / Phase 2 | Recruiting | Massachusetts General Hospital | 80 | 2024-03-21 | 2026-05-05 |
| Anticoagulation Using Rivaroxaban on Top of Aspirin in Intracranial Atherosclerotic Stenosis Rivaroxaban, Clopidogrel, Aspirin - Ischemic Stroke, Intracranial Atherosclerosis | Phase 2 / Phase 3 | Unknown | The First Affiliated Hospital with Nanjing Medical University | 1180 | 2023-12-30 | 2023-12-21 |
| Clinical Trial to Evaluate if the Laparoscopic Administration of Cells Derived From the Fatty Tissue Can Improve the Inflammatory Stenosis in Patient With Crohn's Disease Adipose derived allogenic mesenchymal stem cells (adAMSC) - Stenosis; Bowel, Crohn Disease | Phase 1 / Phase 2 | Terminated | Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz | 2 | 2022-10-24 | 2025-03-20 |
| New Technologies to Determine Carotid Plaque Vulnerability in Patients With Significant Carotid Plaques Contrast-enhanced ultrasound, Shear Wave Elastography, Ultrasound Examination - Carotid Artery Plaque | Phase 2 | Completed | Mayo Clinic | 54 | 2017-11-15 | 2022-11-25 |
| Recurrent Stenoses in Arteriovenous Fistula (AVF) for Dialysis Access: CuttIng ballooN angioplaSTy Combined wITh Paclitaxel drUg coaTed Balloon Angioplasty, an observatIONal Clinical Study Cutting balloon followed by paclitaxel coated balloon - Dialysis Access Malfunction | Phase 2 | Completed | Singapore General Hospital | 44 | 2017-09-08 | 2021-08-24 |
| A Study Evaluating the Effects of Ataciguat (HMR1766) on Aortic Valve Calcification Ataciguat (HMR1766), Placebo Comparator: Matching Placebo - Aortic Valve Stenosis | Phase 2 | Completed | Mayo Clinic | 35 | 2015-06-01 | 2021-01-22 |
| TranScatheter Aortic Valve RepLacement System US Feasibility Trial Transcatheter aortic valve replacement - Aortic Valve Stenosis | Phase 2 | Unknown | Direct Flow Medical, Inc. | 30 | 2013-08-01 | 2016-10-31 |
| Comparison of Endoscopic Radiofrequency Ablation Versus Photodynamic Therapy for Inoperable Cholangiocarcinoma Self expanding metallic stent (SEMS), Endoscopic radiofrequency ablation (ERFA), Photodynamic therapy (PDT) - Cholangiocarcinoma | Phase 2 / Phase 3 | Unknown | Guangzhou Medical University | 120 | 2012-11-01 | 2013-02-26 |
| Application of Contrast Enhance Ultrasound to Evaluate Hemodynamics Change in MCA With Moderate to Severe Stenosis atorvastatin - Stenosis | Phase 1 / Phase 2 | Unknown | Capital Medical University | 30 | 2012-01-01 | 2012-06-12 |
| Sirolimus Use in Angioplasty for Vascular Access Extension Sirolimus - End Stage Renal Disease, Venous Stenosis | Phase 2 | Completed | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | 17 | 2011-12-01 | 2022-05-16 |
| CopiOs Posterolateral Fusion Procedure Copios - Spondylolisthesis, Stenosis | Phase 2 | Terminated | Zimmer Biomet | 45 | 2010-06-01 | 2015-05-27 |
| Randomized Trial Evaluating Slow-Release Formulation TAXUS Paclitaxel-Eluting Coronary Stents to Treat De Novo Coronary Lesions TAXUS Paclitaxel-Eluting Coronary Stent, Slow-Formulation, Express2 - Coronary Stenosis | Phase 2 / Phase 3 | Completed | Boston Scientific Corporation | 1108 | 2003-02-01 | 2010-08-06 |
Aortic Valve Stenosis (2) · Crohn Disease (2) · Peripheral Arterial Disease (2) · Adenocarcinoma (1) · Atherosclerosis (1) · Bile Duct Diseases (1) · Biliary Tract Diseases (1) · Bites and Stings (1) · Calcinosis (1) · Carcinoma (1) · Carotid Stenosis (1) · Cholangiocarcinoma (1) · Colorectal Neoplasms (1) · Coronary Stenosis (1)
Pathological Conditions, Anatomical (15) · Pathological Conditions, Signs and Symptoms (15) · Cardiovascular Diseases (8) · Vascular Diseases (6) · Arterial Occlusive Diseases (5) · Arteriosclerosis (4) · Digestive System Diseases (3) · Gastrointestinal Diseases (3) · Heart Diseases (3) · Intestinal Diseases (3) · Pathologic Processes (3) · Aortic Valve Disease (2) · Atherosclerosis (2) · Brain Diseases (2) · Central Nervous System Diseases (2)
Sirolimus (2) · 5-chloro-2-(5-chlorothiophene-2-sulfonylamino)-N-(4-(morpholine-4-sulfonyl)phenyl)benzamide (1) · Aspirin (1) · Atorvastatin (1) · Clopidogrel (1) · Contraceptives, Oral (1) · Fibroblast Growth Factor 1 (1) · Photochemotherapy (1) · Rivaroxaban (1) · Transcatheter Aortic Valve Replacement (1)
Mayo Clinic (2) · Boston Scientific Corporation (1) · Capital Medical University (1) · Concept Medical Inc. (1) · Direct Flow Medical, Inc. (1) · Guangzhou Medical University (1) · Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz (1) · London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's (1) · Massachusetts General Hospital (1) · Redx Pharma Ltd (1) · Singapore General Hospital (1) · The First Affiliated Hospital with Nanjing Medical University (1) · Venturis Therapeutics, Inc. (1) · Zimmer Biomet (1)
United States (7) · China (2) · Canada (1) · Singapore (1) · Spain (1)
Anthony Jevnikar, MSc MD (1) · Aparna R Parikh, MD, MS (1) · Brain DeRubertis, MD (1) · Dolores Herreros (1) · E. Murat Tuzcu, MD (1) · Edward Choke, PhD (1) · Eric A Secemsky, MD (1) · Farhana Siddique (1) · Gregg W. Stone, MD (1) · Jordan D Miller, PhD (1) · Kezhong Zhang, Doctor (1) · Masahiko Fujihara, MD (1) · Matthew W Urban (1) · Patrick M McCarthy, MD (1) · Sahil Parikh, MD (1)
PMID 16160130, PMID 20129555, PMID 22496083, PMID 39989354
R01CA263776 (1)