3170 completed, 940 unknown, 855 recruiting, 348 terminated. 2474 Not applicable, 913 Phase 2, 599 Phase 1, 414 Phase 3, 224 Phase 4.
Follow Movement Disorders: new trials by email Literature Review of Movement Disorders trials Research Report on Movement Disorders
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Terazosin And Metabolic Energetics in Parkinson's Disease Terazosin 5 MG, Placebo - Parkinson's Disease (PD) | Phase 2 | Suspended | Ergun Y. Uc | 120 | 2028-07-01 | 2026-10-09 |
| Double-Blind Clinical Trial of Subthalamic Nucleus Deep Brain Stimulation in Early-Stage Parkinson's Disease active subthalamic nucleus deep brain stimulation plus optimal drug therapy, inactive subthalamic nucleus deep brain stimulation plus optimal drug therapy - Parkinson Disease | Not applicable | Not yet recruiting | Mallory Hacker | 40 | 2028-01-01 | 2026-02-20 |
| Study to Evaluate the Safety, Tolerability, Efficacy, and PK of FHL-301 in Parkinson's Disease Patients. Gemfibrozil, Placebo - Parkinson Disease | Phase 2 | Withdrawn | Forest Hills Lab | 2027-11-01 | 2026-08-19 | |
| Terazosin for Dementia With Lewy Bodies Terazosin Hydrochloride, Placebo - Dementia With Lewy Bodies | Phase 1 / Phase 2 | Not yet recruiting | Qiang Zhang | 40 | 2027-10-01 | 2026-03-12 |
| A Study to Evaluate the Safety, Tolerability and Efficacy of MT101-5 in Subjects With Early Parkinson's Disease MT101-5 - Parkinson's Disease | Phase 2 | Not yet recruiting | Mthera Pharma Co., Ltd. | 120 | 2027-09-01 | 2026-10-16 |
| Function-based Accelerated Stimulation Therapy (FAST-therapy) for Freezing of Gait (FOG) After Parkinson's Disease (PD) rTMS - Parkinson Disease | Not applicable | Not yet recruiting | University of Michigan | 20 | 2027-09-01 | 2026-10-20 |
| Gastrointestinal Dopamine Decarboxylase and Levodopa Pharmacokinetics Levodopa (L-dopa) - Parkinson's Disease | Phase 4 | Not yet recruiting | Beth Israel Deaconess Medical Center | 40 | 2027-07-01 | 2026-08-28 |
| Fecal MicrobiotaTransplant for the Treatment of Parkinson's Disease Fecal Microbiota Transplant - Parkinson Disease | Phase 1 | Not yet recruiting | ProgenaBiome | 10 | 2027-07-01 | 2026-10-09 |
| Engage-PD: a Physical Activity Coaching Program Via Telehealth for People With Parkinson's Disease. A Single-cohort Study in Spain. Physical Activity Coaching - PARKINSON DISEASE (Disorder) | Not applicable | Not yet recruiting | Hospital Clinic of Barcelona | 30 | 2027-06-01 | 2026-10-05 |
| Sustained Release Oral Formulation For Treatment Of Parkinsons Disease Formulation A, Formulation B, Formulation C - Healthy Volunteers | Phase 1 / Phase 2 | Not yet recruiting | University of Minnesota | 32 | 2027-04-01 | 2026-10-01 |
| Multi-Modal Digital Monitoring of Disease Symptoms Huntington's Disease Huntington Disease | Not yet recruiting | BioSensics | 75 | 2027-01-31 | 2026-10-13 | |
| A Study of AB-1005 Gene Therapy in Japanese Adults With Moderate Parkinson's Disease (J-REGENERATE-PD) AB-1005 - Parkinson Disease | Phase 2 | Not yet recruiting | Bayer | 8 | 2027-01-25 | 2026-07-29 |
| Digital Health Technologies for Progressive Supranuclear Palsy and Dementia With Lewy Bodies Progressive Supranuclear Palsy(PSP), Dementia With Lewy Bodies (DLB) | Not yet recruiting | BioSensics | 60 | 2027-01-15 | 2026-10-13 | |
| Exploring the Efficacy of the Effortful Swallow Maneuver for Improving Swallowing in People With PD Effortful swallow - Dysphagia, Parkinson Disease (PD) | Not applicable | Not yet recruiting | University of Alberta | 74 | 2027-01-01 | 2026-08-19 |
| A Trial of ONO-2808 in Participants With the Parkinsonian Subtype of Multiple System Atrophy (MSA-P) ONO-2808, Placebo - Multiple System Atrophy, Parkinson Variant | Phase 3 | Not yet recruiting | Ono Pharmaceutical Co., Ltd. | 486 | 2027-01-01 | 2026-09-17 |
| Probing Gut-Brain Communication in Parkinson's Disease taVNS, Sham taVNS - Parkinson Disease (PD) | Not applicable | Not yet recruiting | Spaulding Rehabilitation Hospital | 45 | 2027-01-01 | 2026-10-08 |
| Disease-modifying Efficacy of Sitagliptin Therapy in Early-stage Parkinson's Disease Sitagliptin, Sitagliptin placebo - Parkinson Disease | Phase 2 | Not yet recruiting | Yonsei University | 160 | 2026-12-15 | 2026-09-10 |
| Utilization of Aerobic Exercise to Maintain Neurologic Health Aerobic Exercise - Parkinson's Disease | Not applicable | Not yet recruiting | The Cleveland Clinic | 100 | 2026-12-15 | 2026-10-20 |
| Brain Iron in Beta-Propeller Protein Associated Neurodegeneration (BPAN) Standardized brain MRI including specific sequences usable for Quantitative Susceptibility Mapping (QSM) - Neurodegeneration With Brain Iron Accumulation (NBIA), Iron Metabolism Disorders | Not applicable | Not yet recruiting | University Hospital, Bordeaux | 3 | 2026-12-01 | 2026-10-09 |
| Bayesian Optimization of DBS for Gait Deep Brain Stimulation - Parkinson Disease (PD) | Early Phase 1 | Recruiting | University of Minnesota | 15 | 2026-12-01 | 2026-09-28 |
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Parkinson Disease (4474) · Huntington Disease (291) · Essential Tremor (266) · Lewy Body Disease (236) · Alzheimer Disease (232) · Tourette Syndrome (232) · Parkinsonian Disorders (213) · Multiple System Atrophy (204) · Dyskinesias (173) · Cognitive Dysfunction (170) · Supranuclear Palsy, Progressive (170) · Motor Activity (167) · Neurodegenerative Diseases (158) · Dementia (155)
Central Nervous System Diseases (5975) · Nervous System Diseases (5937) · Brain Diseases (5465) · Basal Ganglia Diseases (5436) · Neurodegenerative Diseases (5289) · Synucleinopathies (4713) · Parkinsonian Disorders (4479) · Pathological Conditions, Signs and Symptoms (1378) · Mental Disorders (1287) · Signs and Symptoms (1196) · Neurologic Manifestations (1055) · Neurocognitive Disorders (786) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (720) · Genetic Diseases, Inborn (702)
Deep Brain Stimulation (110) · Levodopa (93) · Exercise (84) · carbidopa, levodopa drug combination (80) · Transcranial Magnetic Stimulation (71) · Transcranial Direct Current Stimulation (61) · Pramipexole (47) · rasagiline (47) · rotigotine (43) · opicapone (42) · Physical Therapy Modalities (39) · Carbidopa (37) · Blood Specimen Collection (29) · Control Groups (29) · Apomorphine (27)
National Institute of Neurological Disorders and Stroke (NINDS) (139) · University of Florida (59) · Bial - Portela C S.A. (56) · Assistance Publique - Hôpitaux de Paris (48) · Boehringer Ingelheim (44) · University of Minnesota (44) · Oregon Health and Science University (43) · VA Office of Research and Development (43) · University Hospital, Toulouse (42) · Institut National de la Santé Et de la Recherche Médicale, France (41) · Washington University School of Medicine (40) · Radboud University Medical Center (36) · University of Colorado, Denver (35) · AbbVie (34) · Vanderbilt University Medical Center (34)
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