6 completed, 2 recruiting, 1 not yet recruiting, 1 terminated. 12 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 12 | Completed 6, Recruiting 2, Not yet recruiting 1, Terminated 1, Unknown 1, Withdrawn 1 |
Follow Ankle Fractures: new trials by email Literature Review of Ankle Fractures trials Research Report on Ankle Fractures
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Buprenorphine as a Post-operative Analgesic in Opioid-Naive Patients After Ankle Fracture Surgery Buprenorphine Transdermal System, Placebo Patch - Pain, Postoperative, Ankle Fracture Surgery | Phase 4 | Recruiting | Jenna-Leigh Wilson | 100 | 2025-04-21 | 2026-04-06 |
| Compression Therapy for Swelling Management Following Ankle Injury Compression sleeve - Ankle Fracture, Ankle Arthrodesis | Phase 4 | Not yet recruiting | Nova Scotia Health Authority | 50 | 2025-04-01 | 2025-01-24 |
| Rebound Pain Following Regional Anaesthesia for Ankle Fracture Surgery continuous infusion of levobupivacaine, oxycodone - Ankle Fracture (Bimalleolar Equivalent, Bimalleolar, or Trimalleolar), Ankle Fracture - Lateral Malleolus | Phase 4 | Completed | University College Cork | 120 | 2023-10-16 | 2026-08-19 |
| Exparel Use in Peripheral Nerve Blocks and Local Infiltration for Foot and Ankle Surgery Exparel, Peripheral Nerve Block - Pain, Postoperative, Pain, Acute Postoperative | Phase 4 | Completed | St. Luke's Hospital, Pennsylvania | 248 | 2022-03-01 | 2026-04-28 |
| CBD for Pain Reduction and Opioid Use After Ankle and Tibia Fracture ORIF CBD, Placebo - Ankle Fractures, Tibia Fracture | Phase 4 | Withdrawn | NYU Langone Health | 2021-10-01 | 2022-01-28 | |
| Randomized Controlled Trial for Ankle Fracture Pain Control Long-Acting Local Anesthesia, Regional Anesthesia - Ankle Fractures | Phase 4 | Recruiting | Lahey Clinic | 70 | 2020-09-01 | 2026-10-08 |
| Comparing Function, Pain and Return to Work in Conservative Versus Surgical Treated Stable Lateral Malleolar Fractures Surgical intervention - Malleolus Fracture, Lateral | Phase 4 | Terminated | Insel Gruppe AG, University Hospital Bern | 3 | 2018-05-01 | 2023-03-08 |
| Efficacy of Multimodal Periarticular Injections in Operatively Treated Ankle Fractures Ropivacaine, Epinephrine, Morphine - Pain, Postoperative, Ankle Fractures | Phase 4 | Completed | University of Iowa | 100 | 2016-10-01 | 2023-12-15 |
| Ankle Fractures Treated With Teriparatide Forsteo - Fracture, Ankle | Phase 4 | Unknown | Nottingham University Hospitals NHS Trust | 10 | 2016-10-01 | 2016-11-04 |
| Effect of Toradol on Post-operative Foot and Ankle Healing Ketorolac, No ketorolac - Ankle Fractures, Trauma Injury | Phase 4 | Completed | Rothman Institute Orthopaedics | 128 | 2016-08-01 | 2018-11-01 |
| Analgesic Benefits of Perineural Versus Intravenous Dexamethasone in Patients Receiving Sciatic Nerve Block Dexamethasone, Saline - Fracture of Ankle | Phase 4 | Completed | Northwestern University | 80 | 2012-06-01 | 2014-11-20 |
| Outcomes of Operative Treatment of Unstable Ankle Fracture - Comparison Between Metallic and Biodegradable Implants fixation of the ankle fracture (Solco ), fixation of the ankle fracture (Freedom) - Ankle Fracture | Phase 4 | Completed | National Police Hospital | 109 | 2008-06-01 | 2011-09-09 |
Pain, Postoperative (3) · Accidental Injuries (1) · Agnosia (1) · Ankle Injuries (1) · Disease (1) · Opioid-Related Disorders (1) · Tibial Fractures (1)
Fractures, Bone (12) · Leg Injuries (12) · Wounds and Injuries (12) · Ankle Injuries (11) · Neurologic Manifestations (4) · Pathological Conditions, Signs and Symptoms (4) · Signs and Symptoms (4) · Pain (3) · Pathologic Processes (3) · Postoperative Complications (3) · Chemically-Induced Disorders (1) · Mental Disorders (1) · Narcotic-Related Disorders (1) · Nervous System Diseases (1) · Neurobehavioral Manifestations (1)
Sodium Chloride (2) · Anesthesia, Conduction (1) · Bupivacaine (1) · Calcium Dobesilate (1) · Dexamethasone (1) · Epinephrine (1) · Ketorolac (1) · Ketorolac Tromethamine (1) · Morphine (1) · Oxycodone (1) · Ropivacaine (1) · Saline Solution (1) · Surgical Procedures, Operative (1) · Teriparatide (1)
Insel Gruppe AG, University Hospital Bern (1) · Jenna-Leigh Wilson (1) · Lahey Clinic (1) · NYU Langone Health (1) · National Police Hospital (1) · Northwestern University (1) · Nottingham University Hospitals NHS Trust (1) · Nova Scotia Health Authority (1) · Rothman Institute Orthopaedics (1) · St. Luke's Hospital, Pennsylvania (1) · University College Cork (1) · University of Iowa (1)
United States (6) · Canada (1) · Ireland (1) · South Korea (1) · Switzerland (1) · United Kingdom (1)
Angus Wallace (1) · Anna Ng-Pellegrino (1) · Brian D O'Donnell, MBBChBAO MSc FCARCSI MD (1) · Eric Swart, MD (1) · Fabian Krause, PD Dr. (1) · Jenna Wilson, MD (1) · Jung Ho Noh, M.D., Ph.D. (1) · Kyle Hancock, MD (1) · Philipp Leucht, MD (1) · Rohit Rahangdale, MD (1) · Steven Raikin, MD (1)
2015 (1), 2017 (1)