30 completed, 17 terminated, 17 withdrawn, 5 recruiting. 29 Not applicable, 7 Phase 4, 6 Phase 2, 3 Phase 3, 2 Phase 1.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Reducing Pain With Methadone and Ketamine in Liver Transplant Methadone, ketamine, Hydromorphone - Liver Transplantation | Phase 4 | Completed | Lahey Clinic | 50 | 2025-06-30 | 2026-08-11 |
| Assessing Outcomes of Coil Embolization for Unilateral vs Bilateral Chronic Subdural Hematomas embolization therapy Bilateral, embolization therapy Unilateral - Chronic Subdural Hematoma | Not applicable | Recruiting | Lahey Clinic | 400 | 2025-04-09 | 2026-07-20 |
| Using Urine Tumor DNA to De-Intensify Surveillance in Non-Muscle Invasive Bladder Cancer UroAmp Test (Convergent Genomics, Inc.) - Non-muscle Invasive Bladder Cancer (NMIBC) | Not applicable | Recruiting | Lahey Clinic | 56 | 2025-01-01 | 2026-11-03 |
| Anamorelin Study for Advanced Pancreatic Cancer Anamorelin Hydrochloride, Placebo - Metastatic Pancreatic Cancer | Phase 2 | Terminated | Lahey Clinic | 4 | 2023-04-01 | 2025-11-17 |
| MIS Hematoma Evacuation NICO BrainPathâ„¢ System - Intracranial Hematoma | Withdrawn | Lahey Clinic | 2021-10-01 | 2021-12-16 | ||
| Probiotic Bladder Instillation for Prevention of Catheter Associated UTIs in Chronically Catheterized Patients Femdophilus probiotic, Normal Saline - Urinary Tract Infections | Early Phase 1 | Withdrawn | Lahey Clinic | 2021-04-01 | 2021-07-08 | |
| Re-operation Rates of Concorde Bullet Device Versus Conduit Titanium Interbody Graft for Lumbar Fusion Conduit Titanium Interbody Graft, Concorde Bullet Device - Degenerative Spondylolisthesis, Lumbar Spondylosis | Completed | Lahey Clinic | 100 | 2021-03-12 | 2024-07-03 | |
| ILAs in CT Lung Cancer Screening Population Retrospective observational study - Interstitial Lung Disease, IPF | Completed | Lahey Clinic | 1703 | 2021-01-30 | 2021-08-03 | |
| Real-World Safety Analysis of Paclitaxel Devices Used for the Treatment of Peripheral Arterial Disease Paclitaxel - Peripheral Arterial Disease | Completed | Lahey Clinic | 8000 | 2020-11-20 | 2022-02-14 | |
| Randomized Controlled Trial for Ankle Fracture Pain Control Long-Acting Local Anesthesia, Regional Anesthesia - Ankle Fractures | Phase 4 | Recruiting | Lahey Clinic | 70 | 2020-09-01 | 2026-10-08 |
| Stereotactic Body Radiation Therapy (SBRT) vs Trans-Arterial Chemoembolization (TACE) as Bridge to Transplant Stereotactic Body Radiation Therapy (SBRT), Trans-Arterial Chemoembolization (TACE), Doxorubin - Hepatocellular Carcinoma, HCC | Phase 3 | Terminated | Lahey Clinic | 9 | 2020-03-01 | 2024-08-28 |
| Efficacy of Near-Infrared Vein Imaging for Difficult IV Placement Near Infrared Vein Imaging, Conventional IV placement - Catheterization, Peripheral | Not applicable | Terminated | Lahey Clinic | 38 | 2020-01-22 | 2022-03-04 |
| Prospective Randomized Clinical Trial Comparing Outcomes of Secondary Intention Wound Care Methods Debridement - Wound Surgical, Wound Heal | Not applicable | Completed | Lahey Clinic | 8 | 2019-12-03 | 2021-03-23 |
| Blood Transfusion by Boston MedFlight Registry Hemorrhagic Shock | Unknown | Massachusetts General Hospital | 500 | 2019-11-01 | 2021-09-01 | |
| Preoperative Corticosteroid Epidural Injection and Lumbar Decompression Surgery Outcomes Corticosteroid injection - Lumbar Radiculopathy | Not applicable | Withdrawn | Lahey Clinic | 2018-09-10 | 2020-06-18 | |
| Fractionated Docetaxel and Radium 223 in Metastatic Castration-Resistant Prostate Cancer Docetaxel, Radium 223 - Metastatic Castrate Resistant Prostate Cancer | Phase 1 | Completed | Tufts Medical Center | 43 | 2018-01-30 | 2025-10-07 |
| SLIP II Registry: Spinal Laminectomy Versus Instrumented Pedicle Screw Fusion Expert Panel Review - Lumbar Spondylolisthesis, Grade 1 Spondylolisthesis | Not applicable | Active not recruiting | Lahey Clinic | 662 | 2017-10-17 | 2026-10-21 |
| Does Preoperative Calcium and Calcitriol Decrease Rates of Post Thyroidectomy Hypocalcemia? Tums, Calcitriol - Hypocalcemia, Thyroid Diseases | Not applicable | Completed | Lahey Clinic | 82 | 2017-08-01 | 2019-07-09 |
| VQI DELTA Paclitaxel Device Safety Analysis Paclitaxel, Non-drug coated Device Treatment - Peripheral Vascular Disease | Completed | Lahey Clinic | 219483 | 2017-01-01 | 2020-10-19 | |
| STAMCAR: A Prospective EC-IC Bypass Registry EC-IC bypass - Carotid Occlusion | Withdrawn | Lahey Clinic | 2016-09-01 | 2022-03-04 |
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Carcinoma, Hepatocellular (3) · Prostatic Neoplasms (3) · Heart Diseases (2) · Lung Diseases, Interstitial (2) · Pain (2) · Pain, Postoperative (2) · Sinusitis (2) · Spondylolisthesis (2) · Supranuclear Palsy, Progressive (2) · Urethral Stricture (2) · Urinary Bladder Neoplasms (2) · Urinary Incontinence, Stress (2) · Acute Kidney Injury (1) · Acute Pain (1) · Agnosia (1)
Bacitracin (2) · Chemoembolization, Therapeutic (2) · Cisplatin (2) · Dexamethasone (2) · Doxorubicin (2) · Gemcitabine (2) · Lidocaine (2) · Paclitaxel (2) · Radiosurgery (2) · Radiotherapy (2) · coenzyme Q10 (2) · Adrenal Cortex Hormones (1) · Aging (1) · Amifampridine (1) · Anesthesia, Conduction (1)
United States (72) · Canada (4) · Israel (1) · Italy (1) · Lithuania (1)
Zoher Ghogawala, MD (5) · David R Riker, MD (2) · Diana Apetauerova, MD (2) · Sherif B. Labib, M.D. (2) · Thomas Schnelldorfer, MD (2) · Akmal Sarwar, M.D. (1) · Alexander Sherman (1) · Carla R Lamb, M.D. (1) · Carlos David, MD (1) · Christoph Wald, M.D., Ph.D (1) · Christopher G. Tretter, M.D. (1) · Corrine Zarwan, MD (1) · Daniel Bertges, MD (1) · David Brams, MD (1)
PMID 12971199, PMID 20925139, PMID 21063011, PMID 21371573, PMID 21953370, PMID 23583245, PMID 25111080, PMID 25491915, PMID 26194251, PMID 27583276, PMID 28097332, PMID 28514621, PMID 30561254, PMID 30747949, PMID 30831175, PMID 31926836, PMID 32370548, PMID 33631337, PMID 33687463, PMID 34887051, PMID 36266481, PMID 36782326, PMID 38912784, PMID 41196064
K12DK083021 (2), R01CA120950 (1)