14 completed. 14 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 14 | Completed 14 |
Follow Agitation: new trials by email Literature Review of Agitation trials Research Report on Agitation
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Emergence Agitation After Nasal Surgery: a Randomized Controlled Comparison Between Melatonin and Mirtazapine Mirtazapine, Melatonin, Placebo - Agitation | Phase 4 | Completed | Ain Shams University | 165 | 2021-06-15 | 2022-04-15 |
| TREC-Lebanon: A Trial for Rapid Tranquilisation for Agitated Patients in the Emergency Setting Haloperidol + Promethazine + Chlorpromazine, Haloperidol + Promethazine - Psychiatric Emergency, Aggression | Phase 4 | Completed | Joseph Dib | 100 | 2018-08-28 | 2022-06-14 |
| Phase IV to Evaluate the Safety of Self-administered ADASUVE® in Agitated Patients Outside the Hospital Setting Staccato® Delivery System Loxapine (ADASUVE®) - Agitation | Phase 4 | Completed | Ferrer Internacional S.A. | 323 | 2016-09-08 | 2020-11-04 |
| Comparison of Ketamine-propofol Combinations Ketamine-propofol mixture - Agitation, Postoperative Pain | Phase 4 | Completed | Cukurova University | 75 | 2016-07-01 | 2017-04-20 |
| Scalp Nerve Block on Emergence Agitation Ropivacaine, Remifentanil, Sevoflurane - Agitation | Phase 4 | Completed | Ajou University School of Medicine | 44 | 2015-05-01 | 2017-01-25 |
| Study of Sedative Medications in Patients With Severe Infection and Respiratory Failure Propofol, Dexmedetomidine, Fentanyl - Sepsis, Respiratory Failure | Phase 4 | Completed | Texas Tech University Health Sciences Center | 36 | 2014-08-01 | 2020-03-02 |
| Dexmedetomidine to Prevent Agitation After Free Flap Surgery Dexmedetomidine, Saline placebo - Agitation, Delirium | Phase 4 | Completed | Peking University | 80 | 2013-06-01 | 2014-11-13 |
| Treating Acutely Agitated Patients With Asenapine Sublingual Tablets Asenapine, Placebo - Agitation | Phase 4 | Completed | Unity Health Toronto | 120 | 2012-04-01 | 2016-05-16 |
| Effect of Single-dose Dexmedetomidine on Emergence Excitement in Adults With Nasotracheal Intubation After Orthognathic Surgery saline, Dexmedetomidine - Agitation | Phase 4 | Completed | Yonsei University | 74 | 2011-10-01 | 2015-02-06 |
| Escitalopram Treatment for BPSD in Alzheimer's Disease in Comparison to Risperidone Escitalopram, Risperidone - Agitation, Psychosis | Phase 4 | Completed | Abarbanel Mental Health Center | 40 | 2008-04-01 | 2015-06-24 |
| A Comparison Study of the Efficacy of Quetiapine and Haloperidol in Agitated Adults in Emergency Room Quetiapine, Haloperidol, Lorazepam - Agitation | Phase 4 | Completed | University of Southern California | 72 | 2006-05-01 | 2019-07-26 |
| Antipsychotic Discontinuation in Alzheimer's Disease risperidone - Alzheimer Disease, Psychotic Disorders | Phase 4 | Completed | New York State Psychiatric Institute | 180 | 2004-08-01 | 2013-04-24 |
| Liquid Risperidone in the Treatment of Acute Agitation in Psychiatrically Hospitalized Children risperidone - Agitation | Phase 4 | Completed | Stony Brook University | 24 | 2003-01-01 | 2008-11-13 |
| Treatment of Behavioral Symptoms in Alzheimer's Disease Haloperidol-Haloperidol, Haloperidol-Placebo - Alzheimer's Disease, Psychosis | Phase 4 | Completed | New York State Psychiatric Institute | 44 | 1999-01-01 | 2016-05-24 |
Psychomotor Agitation (14) · Psychotic Disorders (4) · Alzheimer Disease (3) · Aggression (2) · Schizophrenia (2) · Bipolar Disorder (1) · Delirium (1) · Dementia (1) · Pain, Postoperative (1) · Respiratory Insufficiency (1) · Sepsis (1)
Aberrant Motor Behavior in Dementia (14) · Behavior (14) · Behavioral Symptoms (14) · Dyskinesias (14) · Nervous System Diseases (14) · Neurobehavioral Manifestations (14) · Neurologic Manifestations (14) · Pathological Conditions, Signs and Symptoms (14) · Psychomotor Disorders (14) · Signs and Symptoms (14) · Mental Disorders (6) · Schizophrenia Spectrum and Other Psychotic Disorders (5) · Neurocognitive Disorders (4) · Brain Diseases (3) · Central Nervous System Diseases (3)
Dexmedetomidine (3) · Haloperidol (3) · Risperidone (3) · Benztropine (1) · Chlorpromazine (1) · Dexetimide (1) · Escitalopram (1) · Fentanyl (1) · Lorazepam (1) · Melatonin (1) · Mirtazapine (1) · Promethazine (1) · Propofol (1) · Quetiapine Fumarate (1) · Remifentanil (1)
New York State Psychiatric Institute (2) · Abarbanel Mental Health Center (1) · Ain Shams University (1) · Ajou University School of Medicine (1) · Cukurova University (1) · Ferrer Internacional S.A. (1) · Joseph Dib (1) · Peking University (1) · Stony Brook University (1) · Texas Tech University Health Sciences Center (1) · Unity Health Toronto (1) · University of Southern California (1) · Yonsei University (1)
United States (6) · South Korea (2) · China (1) · Egypt (1) · Israel (1) · Lebanon (1) · Spain (1) · Turkey (Türkiye) (1)
Davangere Devanand, M.D. (1) · Davangere P. Devanand, MD (1) · David Frey, MD (1) · Gabrielle A Carlson, MD (1) · George M Simpson, MD (1) · Jong Yeop Kim, MD (1) · Kenneth Nugent, MD (1) · Laura Leso, MD (1) · Michael J Pratts, MD (1) · Thais B Teixeira, PharmD, PhD (1) · Yonhee Shim (1) · Yoram Barak, MD, MHA (1)
PMID 21845596, PMID 23075176, PMID 24606117, PMID 27855483, PMID 29249041, PMID 30282677, PMID 32528650
R01AG021488 (1), R01MH055735 (1)