Ulcer: Clinical Trials

34 completed. 34 Phase 2, 4 Phase 1, 3 Phase 3.

By phase and status

Phase	Trials	Status
Phase 2	34	Completed 34
Phase 1	4	Completed 4
Phase 3	3	Completed 3

Follow Ulcer: new trials by email Literature Review of Ulcer trials Research Report on Ulcer

Trials (filtered) newest first · largest first

All 34 trials

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

Trial	Phase	Status	Sponsor	Enrollment	Start	Updated
A Study Evaluating the Effects of GLPG3970 Given as an Oral Treatment for 6 Weeks in Adults With Ulcerative Colitis GLPG3970, Placebo - Ulcerative Colitis	Phase 2	Completed	Lakefront Biotherapeutics NV	31	2020-10-05	2023-01-27
Intra-oral Treatment of OLP With Rivelin®-CLO Patches Clobetasol Propionate - Oral Lichen Planus	Phase 2	Completed	Dermtreat	140	2018-06-28	2020-07-14
Melatonin for Prevention of Radiation Induced Oral Mucositis Rapid Release Capsules Melatonin, 10 mg, Miconaz oral gel, BBC oral spray - Oral Mucositis (Ulcerative) Due to Radiation	Phase 2	Completed	Hams Hamed Abdelrahman	40	2018-01-12	2019-06-17
Efficacy and Safety of Ustekinumab, a Human Monoclonal Anti-IL-12/IL-23 Antibody, in Patients With Behçet Disease Subcutaneous Ustekinumab - Behçet Disease	Phase 2	Completed	Assistance Publique - Hôpitaux de Paris	16	2017-06-14	2025-09-08
A Safety and Efficacy Study of LiRIS® in Females With Interstitial Cystitis With Hunner's Lesions LiRIS®, LiRIS Placebo - Cystitis, Interstitial, Ulcer	Phase 2	Completed	Allergan	59	2015-04-15	2018-10-05
Topical PluroGel PN for the Treatment of Mildly Infected Diabetic Foot Ulcers Plurogel PN - Diabetic Foot Ulcer, Infection	Phase 2	Completed	PluroGen Therapeutics, Inc	15	2013-10-01	2014-09-25
Topical PluroGel N for the Treatment of Mildly Infected Diabetic Foot Ulcers PluroGel N, PluroGel - Diabetic Foot Ulcer, Infection	Phase 2	Completed	PluroGen Therapeutics, Inc	42	2013-10-01	2014-09-25
Nitric Oxide Generating Gel Dressing in Patients With Diabetic Foot Ulcers NOx dressing, Standard of Care - Diabetic Foot Ulcer	Phase 1 / Phase 2	Completed	Edixomed Ltd	130	2013-06-01	2016-01-20
Evaluate Misoprostol for the Healing of Small Bowel Ulcers in Low-dose Aspirin Users Complicated by Small Bowel Bleeding Misoprostol, Placebo - Ulcer Hemorrhage	Phase 2 / Phase 3	Completed	Chinese University of Hong Kong	82	2013-04-01	2019-01-31
The Effect of the Cosmetic Cream NMBM on Leg Ulcers - a Pilot Study NMBM, Compression garments - Ulcer, Venous Ulcer	Phase 1 / Phase 2	Completed	M.D. Lederman Consulting Ltd	30	2013-02-01	2017-01-11
A Study to Investigate the Safety and Clinical Effect of Nexagon® as a Topical Treatment for Subjects With a Diabetic Foot Ulcer (DUNE) Nexagon® Low Dose, Nexagon® Medium Dose, Nexagon® High Dose - Diabetic Foot Ulcers	Phase 2	Completed	OcuNexus Therapeutics, Inc.	168	2012-07-01	2014-05-01
Safety and Efficacy Study Using Gene Therapy for Critical Limb Ischemia NL003, Normal Saline - Arterial Occlusive Disease, Ulcers	Phase 2	Completed	Beijing Northland Biotech. Co., Ltd.	200	2012-03-01	2020-01-22
A Study to Investigate the Efficacy, Safety and Tolerability of Nexagon® as a Topical Treatment for Subjects With Venous Leg Ulcers Nexagon® Low Dose, Nexagon® High Dose, Nexagon® Vehicle - Venous Leg Ulcers	Phase 2	Completed	OcuNexus Therapeutics, Inc.	300	2011-05-01	2014-05-01
A Clinical Study of the Safety and Efficacy of MEBO Wound Ointment in Subjects With Venous Leg Ulcers MEBO Wound Ointment (MEBO), Standard of Care - Ulcers	Phase 2	Completed	Skingenix, Inc.	5	2010-11-01	2025-11-06
Ability of Curcumin to Decrease Cytokines Involved in Mucositis in the Autologous Transplant Curcumin Lozenges - Oral Mucositis (Ulcerative)	Phase 2	Completed	Tata Memorial Centre	40	2010-10-06	2024-04-11
Digital Ischemic Lesions in Scleroderma Treated With Oral Treprostinil Diethanolamine treprostinil diethanolamine, placebo - Systemic Sclerosis, Scleroderma	Phase 2	Completed	United Therapeutics	148	2009-05-01	2023-12-28
A Dose Finding Study of Topically Applied I-020201 as an Adjunct to Good Standard-of-care in Patients With Chronic Diabetic Foot Ulcers Good Standard of Care (GSoC), Vehicle, I-020201 - Diabetic Foot Ulcer	Phase 2	Completed	Kuros Biosurgery AG	211	2009-05-01	2012-03-16
The CareFUL Prevention Trial TrueContour® Insole, Current standard of care insole - Plantar Ulcer, Diabetes	Phase 2	Completed	DIApedia, LLC	130	2009-02-01	2014-08-13
Safety Study of Topical Doxycycline Gel for Adult Diabetic Lower Extremity Ulcers doxycycline, placebo gel - Diabetic Foot Ulcer	Phase 2	Completed	NanoSHIFT LLC	15	2009-01-01	2017-04-07
Study of COLAL-PRED to Treat Moderate to Severe Ulcerative Colitis Placebo, COLAL-PRED - Colitis, Ulcerative	Phase 2	Completed	Prometheus Laboratories	190	2008-05-01	2010-09-29

Showing 20 of 34. Sign in to see all of them.

Narrower conditions

Diabetic Foot (10)  ·  Wounds and Injuries (6)  ·  Diabetes Mellitus (4)  ·  Infections (4)  ·  Colitis (3)  ·  Colitis, Ulcerative (3)  ·  Ischemia (3)  ·  Peripheral Vascular Diseases (3)  ·  Abscess (2)  ·  Arterial Occlusive Diseases (2)  ·  Burns (2)  ·  Cellulitis (2)  ·  Chronic Limb-Threatening Ischemia (2)  ·  Foot Ulcer (2)

Broader conditions

Pathologic Processes (34)  ·  Pathological Conditions, Signs and Symptoms (34)  ·  Skin and Connective Tissue Diseases (20)  ·  Skin Diseases (17)  ·  Cardiovascular Diseases (15)  ·  Vascular Diseases (14)  ·  Skin Ulcer (12)  ·  Endocrine System Diseases (11)  ·  Leg Ulcer (11)  ·  Diabetes Complications (10)  ·  Diabetic Angiopathies (10)  ·  Diabetic Neuropathies (9)  ·  Foot Ulcer (9)  ·  Diabetes Mellitus (7)  ·  Gastrointestinal Diseases (5)

Interventions

Standard of Care (4)  ·  Acyclovir (2)  ·  Levofloxacin (2)  ·  Saline Solution (2)  ·  Vancomycin (2)  ·  telavancin (2)  ·  Analgesia (1)  ·  Anti-Inflammatory Agents, Non-Steroidal (1)  ·  Clobetasol (1)  ·  Doxycycline (1)  ·  Melatonin (1)  ·  Methylprednisolone (1)  ·  Misoprostol (1)  ·  Ofloxacin (1)  ·  Pantoprazole (1)

Sponsors

Cumberland Pharmaceuticals (2)  ·  OcuNexus Therapeutics, Inc. (2)  ·  PluroGen Therapeutics, Inc (2)  ·  Allergan (1)  ·  AnGes USA, Inc. (1)  ·  Assistance Publique - Hôpitaux de Paris (1)  ·  Beijing Northland Biotech. Co., Ltd. (1)  ·  Centers for Disease Control and Prevention (1)  ·  Chinese University of Hong Kong (1)  ·  DIApedia, LLC (1)  ·  Dermtreat (1)  ·  Diabetica Solutions Inc. (1)  ·  Edixomed Ltd (1)  ·  French National Agency for Research on AIDS and Viral Hepatitis (1)  ·  Hams Hamed Abdelrahman (1)

Countries

United States (22)  ·  Canada (3)  ·  United Kingdom (3)  ·  China (2)  ·  Germany (2)  ·  Japan (2)  ·  Russia (2)  ·  South Africa (2)  ·  Ukraine (2)  ·  Australia (1)  ·  Central African Republic (1)  ·  Czechia (1)  ·  Denmark (1)  ·  Egypt (1)  ·  France (1)

Top investigators

G. Ralph Corey, MD (2)  ·  Andres Gutierrez, M.D., Ph.D. (1)  ·  Arthur Tucker, PhD (1)  ·  C. Mauli Agrawal, Ph.D. (1)  ·  David G Armstrong, DPM MD PhD (1)  ·  David Lewis, MD (1)  ·  David Prior (1)  ·  David T. Rubin, M.D. (1)  ·  Eglal M Moussa, Phd (1)  ·  Francis KL Chan, MD (1)  ·  Gabriela Paz Bailey, MD (1)

Results publications

PMID 15504999, PMID 18325386, PMID 18623174, PMID 19530940, PMID 19711453, PMID 19715417, PMID 20443734, PMID 21146749, PMID 22659765, PMID 22877866, PMID 24760263, PMID 29966612, PMID 31858338, PMID 34288094, PMID 34864108, PMID 35435039, PMID 38782788, PMID 42728025

NIH funding

R01AR045506 (1), R01DK059961 (1), R44DK059074 (1)