Clobetasol: Clinical Trials

76 trials of Clobetasol, newest first

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47 completed, 9 unknown, 6 recruiting, 6 terminated. 22 Phase 2, 17 Phase 4, 14 Phase 1, 14 Phase 3, 12 Not applicable.

By phase and status

PhaseTrialsStatus
Phase 222Completed 11, Terminated 4, Active not recruiting 2, Recruiting 2, Unknown 2, Withdrawn 1
Phase 417Completed 11, Unknown 3, Not yet recruiting 2, Recruiting 1
Phase 114Completed 9, Terminated 2, Withdrawn 2, Unknown 1
Phase 314Completed 9, Unknown 2, Active not recruiting 1, Terminated 1, Withdrawn 1
Not applicable12Completed 6, Recruiting 2, Unknown 2, Not yet recruiting 1, Terminated 1
Early Phase 12Completed 1, Recruiting 1

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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

TrialPhaseStatusSponsorEnrollmentStartUpdated
Efficacy of Clobetasol Vs Intralesional Triamcinolone in Lichen Planus Treatment
Clobetasol propionate 0.05% cream, Triamcinolone acetonide 10 mg/mL injection - Hypertrophic Lichen Planus
Phase 4Not yet recruitingNoor Aziz502026-10-012026-06-24
The TRIBECA Study (TRIessence/Byqlovi for Easier CAtaract Surgery)
Triamcinolone (Optional), control group - Post Cataract Surgery
Phase 4Not yet recruitingResearch Insight LLC402026-04-012026-03-31
Treatment of Vulvar Lichen Sclerosus With Corticosteroid Ointment, Calcineurin Inhibitor Ointment, and Platelet-Rich Plasma (PRP) Therapy.
Platelet-Rich Plasma (PRP) Treatment, Clobetasol Propionate 0.05% Cream (Dermovate), Pimecrolimus Cream (Elidel) - Vulvar Lichen Sclerosus
Not applicableNot yet recruitingMilosz Pietrus452025-12-012025-11-20
Comparison of the Efficacy of Clobetasol Propionate 0.05% Mouthwash, Photobiomodulation, and Their Combination in Managing of Oral Lesions in Patient With Pemphigus Vulgaris.
Clobetasol propionate 0.05% Mouthwash, diode laser for photobiomodulation, clobetasol propionate 0.05% mouthwash + photobiomodulation - Oral Lesions in Patients With Pemphigus Vulgaris
Not applicableRecruitingDamascus University302025-11-012026-06-11
Effectiveness of Micro-needling With 5 Fluorouracil Versus Potent Topical Steroids in the Treatment of Limited Vitiligo
Microneedling with 5-fluorouracil, Topical application of 0.05% Clobetasol propionate - Vitiligo
Early Phase 1RecruitingCombined Military Hospital (CMH) institute of Medical Sciences Bahawalpur Pakistan402025-08-082026-02-17
Early Intervention in Plaque Psoriasis: is Bimekizumab Able to Delay Chronic Inflammation?
Bimekizumab, Clobetasol - Psoriasis
Phase 2RecruitingCentre Hospitalier Universitaire de Nice402025-07-222026-10-01
ZINCLO-HAND: Zinc and Clobetasol for the Prevention of Regorafenib-Induced Hand-Foot Skin Reaction
Zinc Supplementation, Clobetasol Propionate 0.05% Cream - Hand-Foot Skin Reaction (HFSR)
Not applicableCompletedGazi University1502025-02-202025-09-15
Mucoadhesive Modified-Release Formulations for the Topical Treatment of Symptomatic Oral Lichen Planus
Clobetasol Patch, Clobetasol + Resveratrol Patch, Clobetasol in Orabase - Oral Lichen Planus, Oral Lichen Planus Related Stress
Phase 2RecruitingUniversity of Palermo452024-09-042025-08-03
Enhanced Dermatological Care to Reduce Rash and Paronychia in Epidermal Growth Factor Receptor (EGRF)-Mutated Non-Small Cell Lung Cancer (NSCLC) Treated First-line With Amivantamab Plus Lazertinib
Amivantamab IV, Amivantamab SC, Lazertinib - Carcinoma, Non-Small-Cell Lung
Phase 2Active not recruitingJanssen Research & Development, LLC3052024-02-162026-09-25
Comparison of Laser Treatment With Clobetasol Therapy in Patients With Lichen Sclerosus
Treatment with Monalisa Glide Laser, Treatment with Clobetasol - Lichen Sclerosus
Not applicableRecruitingKantonsspital Winterthur KSW1202023-11-102025-09-23
Anti-Inflammatory Effects of 0.045% Tazarotene/0.01% Halobetasol Lotion in Psoriasis
0.01% Halobetasol, 0.045% Tazarotene, 0.05% Clobetasol Propionate - Psoriasis Vulgaris
Phase 4CompletedDermatology Consulting Services, PLLC102023-07-132023-11-18
A Comparison of Photodynamic Therapy and Topical Clobetasol in Treatment of Oral Lichen Planus: a Split-Mouth Randomised Controlled Study
Photodynamic Therapy, Clobetasol - Oral Lichen Planus
Phase 2CompletedWroclaw Medical University292023-06-012024-12-30
Clobetasol Propionate Ophthalmic Nanoemulsion, 0.05% in the Treatment of Inflammation After Cataract Surgery in Pediatric Population
Clobetasol Propionate, Prednisolone acetate ophthalmic suspension, 1% - Cataracts Infantile
Phase 3UnknownSalvat602022-12-122024-09-27
Phase II Study Evaluating the Clinical Efficacy and Safety of GN-037 in Plaque Psoriasis
GN-037, Clobetasol 17-propionate, Placebo - Psoriasis
Phase 2CompletedGEN İlaç ve Sağlık Ürünleri A.Ş.1902022-12-072025-07-16
Silver Nitrate Versus Topical Steroid For Umbilical Granuloma
Clobetasol Propionate .05 Mg in 100 mL TOPICAL LOTION, Silver Nitrate - Umbilical Granuloma
Phase 2CompletedChildren Hospital and Institute of Child Health, Lahore3542022-09-202024-04-12
Does Steroid Plus CO2 Laser Improve Lichen Sclerosus Symptoms Compared to Steroids Alone?
MonaLisa Touch, Topical steroid - Vulvar Lichen Sclerosus
Phase 2 / Phase 3TerminatedUniversity of South Alabama112022-04-132025-06-18
Fractionated CO2 Laser With and Without Clobetasol for Treatment of Vulvar Lichen Sclerosus
Fractionated CO2-laser, Clobetasol Propionate 0.05% Ointment - Vulvar Lichen Sclerosus
Phase 4CompletedMedstar Health Research Institute2122022-03-012025-06-05
Topical 1% Methotrexate Gel Versus Clobetasol Propionate in Patients With Psoriasis
topical 1% methotrexate gel, clobetasol propionate 0.05% ointment - Pilot Study, Psoriasis
Early Phase 1CompletedDr. Jose N. Rodriguez Memorial Hospital and Sanitarium22022-01-012024-08-16
Plasma Rich in Growth Factors (PRGF) for the Treatment of Lichen Sclerosus Atrophicus of the Vulva
PRGF, Clobetasol Propionate - Lichen Sclerosus of Vulva
Phase 3WithdrawnFundación Eduardo Anitua2021-12-232025-02-27
Laser vs Clobetasol for Lichen Sclerosus
Clobetasol 0.05% Emollient Top Cream, Non-ablative CO2 Laser - Lichen Sclerosus
Phase 3CompletedRuhr University of Bochum2462021-11-022025-12-04

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Conditions studied

Psoriasis (17)  ·  Vulvar Lichen Sclerosus (8)  ·  Lichen Planus, Oral (7)  ·  Inflammation (4)  ·  Lichen Sclerosus et Atrophicus (4)  ·  Dermatitis, Atopic (3)  ·  Pain (3)  ·  Pemphigoid, Bullous (3)  ·  Alopecia (2)  ·  Cataract (2)  ·  Colorectal Neoplasms (2)  ·  Dermatitis (2)  ·  Skin Diseases (2)  ·  Alopecia Areata (1)  ·  Arthritis, Rheumatoid (1)

Sponsors

Galderma R&D (4)  ·  Bayer (3)  ·  LEO Pharma (3)  ·  Salvat (3)  ·  Stiefel, a GSK Company (3)  ·  Actavis Inc. (2)  ·  Assistance Publique - Hôpitaux de Paris (2)  ·  Cairo University (2)  ·  Medstar Health Research Institute (2)  ·  Academic and Community Cancer Research United (1)  ·  Azidus Brasil (1)  ·  Callender Center for Clinical Research (1)  ·  Center for Vulvovaginal Disorders (1)  ·  Centre Hospitalier Universitaire de Nice (1)  ·  Centre Hospitalier Universitaire, Amiens (1)

Countries

United States (29)  ·  Germany (9)  ·  France (7)  ·  Brazil (5)  ·  Canada (4)  ·  Pakistan (3)  ·  Poland (3)  ·  Turkey (Türkiye) (3)  ·  Denmark (2)  ·  Spain (2)  ·  Switzerland (2)  ·  Taiwan (2)  ·  Argentina (1)  ·  China (1)  ·  Egypt (1)

Top investigators

Andrew Schwartz, MD (2)  ·  Ronald W Gottschalk, MD (2)  ·  Soran Hong,, M.D. (2)  ·  Abeer Aljoujou, PhD In Oral medicine (1)  ·  Adeel A Gujjar, M.S (1)  ·  Amy J McMichael, MD (1)  ·  Anders Clemmensen, MD (1)  ·  Andrew T Goldstein, MD (1)  ·  Benjamin Batteux, MD (1)  ·  Catherine Lok, Pr (1)  ·  Cesar W. Noce, DDS, MSD (1)

Results publications

PMID 12424394, PMID 14977340, PMID 24935281, PMID 27810317, PMID 28670710, PMID 42192627, PMID 15568399, PMID 21353334, PMID 22134563, PMID 25592341, PMID 26297574, PMID 28712102, PMID 28793884, PMID 30297352, PMID 31262657, PMID 32726554, PMID 33957642, PMID 34251533, PMID 37145134, PMID 37300792, PMID 38508975, PMID 38754628, PMID 39578347, PMID 39998969, PMID 40923969, PMID 41807108, PMID 42163196, PMID 42208069, PMID 42384057

NIH funding

2008 (1), 2016 (1), 2023 (1), P30CA015083 (1)