68 completed, 15 unknown, 4 recruiting, 3 not yet recruiting. 30 Phase 3, 19 Not applicable, 18 Phase 2, 15 Phase 4, 13 Phase 1.
Follow this drug Literature Review of Acyclovir trials Research Report on Acyclovir
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Efficacy and Safety of Oral Antiviral Therapy for Idiopathic Trigeminal Neuralgia Intervention：Drug: Carbamazepine, Intervention：Drug: Carbamazepine + Acyclovir, Intervention：Drug: Carbamazepine + Celecoxib - Idiopathic Trigeminal Neuralgia | Not applicable | Not yet recruiting | Beijing Tiantan Hospital | 165 | 2026-08-31 | 2026-06-29 |
| Prevention of Recurrence of Herpes Simplex in Autoimmune Rheumatic Diseases Acyclovir (ACV), Placebo - Autoimmune Rheumatic Diseases, Recurrent Herpes Simplex | Phase 4 | Recruiting | University of Sao Paulo General Hospital | 62 | 2026-06-25 | 2026-08-05 |
| Aciclovir Versus Placebo for HSV-2 Meningitis Acyclovir 50 MG/ML, Placebo - Herpes Simplex 2, Meningitis, Viral | Phase 4 | Not yet recruiting | Jacob Bodilsen | 150 | 2026-06-01 | 2025-10-01 |
| Topical Ganciclovir Versus Systemic Aciclovir in the Treatment of Herpetic Keratitis Acyclovir 400 MG, Ganciclovir (GCV) - Herpetic Keratitis | Not applicable | Completed | Al-Azhar University | 20 | 2024-10-01 | 2025-01-03 |
| Individualization of Dosage Regimens in Obese Patients: Application to Acyclovir Acyclovir - Obesity | Phase 1 | Recruiting | University Hospital, Toulouse | 20 | 2024-04-09 | 2025-12-31 |
| Preemptive Treatment With Acyclovir in Intubated and Mechanically Ventilated Patients With Herpes (PTH2) Intravenous acyclovir (ACYCLOVIR ), Saline bags - Invasive Mechanical Ventilation, HSV Throat Reactivation | Not applicable | Not yet recruiting | Assistance Publique - Hôpitaux de Paris | 246 | 2024-03-01 | 2024-01-22 |
| Acyclovir in Ventilated Patients With Pneumonia and HSV-1 in BAL Acyclovir - Pneumonia, Viral, Ventilator Associated Pneumonia | Phase 3 | Recruiting | Jena University Hospital | 616 | 2024-02-20 | 2026-07-23 |
| The Bioequivalence Study of Acyclovir 800 mg Tablet in Healthy Thai Volunteers Under Fasting Conditions Acyclovir 800 mg Tablet, Zovirax™ 800 mg Tablet - Healthy Volunteer | Phase 1 | Unknown | International Bio service | 40 | 2024-02-12 | 2024-01-29 |
| Intralesional Vitamin D3 Versus Intralesional Acyclovir in Treatment of Plantar Warts Vitamin D, acyclovir - Plantar Wart | Not applicable | Unknown | Assiut University | 44 | 2022-10-01 | 2022-04-13 |
| Intralesional Injection of Acyclovir Versus Candida Antigen in Treatment of Plantar Warts Acyclovir 250mg Powder for Solution for Infusion, each vial contains 250mg of acyclovir as the sodium salt, Chandra Bhagat Pharma Pvt. Ltd andcandida antigen - Acyclovir and Candida Antigen in Treatment of Plantar Wart | Phase 4 | Unknown | Sohag University | 40 | 2022-06-13 | 2022-06-23 |
| Effect of Various Treatment Modalities on Dendritic Vial Ulcer Acyclovir, Tobramycin, Fluorometholone - Corneal Ulcer | Unknown | Sohag University | 40 | 2022-03-18 | 2022-04-06 | |
| A Study to Compare Sitavig (Acyclovir) Buccal Tablet With a Placebo in the Treatment of Herpes Labialis in Participants Whose Immune System Works Normally Acyclovir 50mg buccal/topical tablet, BAYM008894/UI1614773, Placebo - Recurrent Herpes Labialis | Phase 3 | Completed | Bayer | 2020 | 2021-11-23 | 2025-09-02 |
| The Effectiveness of Oral Acyclovir in the Treatment of Molluscum Contagiosum in Children Acyclovir, KOH 10 % - Molluscum Contagiosum | Not applicable | Unknown | Dalia Mahran | 35 | 2020-06-15 | 2020-07-20 |
| Pharmacokinetic Properties of 200 and 400 mg Acyclovir Tablet in Indonesia Healthy Subject Acyclovir 200 MG, Acyclovir 400 MG, Zovirax 200 MG Tablet - Drug Use | Not applicable | Completed | PT. Kimia Farma (Persero) Tbk | 56 | 2020-02-21 | 2023-02-09 |
| Topical Corticosteroid Use in Addition to Oral Antivirals for Prevention of Recurrence of Herpes Simplex Virus (HSV) Keratitis oral acyclovir 400 mg BID OR valacyclovir 500 mg qdaily, oral acyclovir 400 mg BID OR valacyclovir 500 mg qdaily + topical corticosteroid eye drops - Herpes Simplex Virus Keratitis | Phase 4 | Withdrawn | NYU Langone Health | 2019-12-10 | 2022-01-14 | |
| Optimized Antibiotic Therapy in Patients With Subarachnoid Haemorrhage (ES) and Cerebral Haemorrhage (EC) Piperacillin/tazobactam, Meropenem, Daptomycin - Therapeutic Drug Monitoring, Subarachnoid Hemorrhage | Unknown | Azienda Sanitaria-Universitaria Integrata di Udine | 104 | 2019-10-01 | 2021-07-21 | |
| A Study of the Safety and Tolerability of ASP7317 in Senior Adults Who Are Losing Their Clear, Sharp Central Vision Due to Geographic Atrophy Secondary to Dry Age-related Macular Degeneration ASP7317, tacrolimus, trimethoprim-sulfamethoxazole - Age-Related Macular Degeneration | Phase 1 | Recruiting | Astellas Institute for Regenerative Medicine | 42 | 2018-07-13 | 2026-09-03 |
| Letermovir Versus Valganciclovir to Prevent Human Cytomegalovirus Disease in Kidney Transplant Recipients (MK-8228-002) Letermovir, Valganciclovir, Acyclovir (ACV) - CMV Disease | Phase 3 | Completed | Merck Sharp & Dohme LLC | 601 | 2018-05-03 | 2023-07-28 |
| EBV Positive Nasopharyngeal Carcinoma Treated With Concurrent Chemo-radiotherapy With or Without Anti-Viral Drug Acyclovir 800 MG, Radiotherapy and chemotherapy - Drug Use for Unapproved Schedule | Phase 3 | Unknown | Kuwait Cancer Control Center | 50 | 2018-05-01 | 2018-09-04 |
| Airway Intervention Registry (AIR): Recurrent Respiratory Papillomatosis (RRP) Microdebrider, Cold-steel surgery (forceps), Carbon dioxide laser - Recurrent Respiratory Papillomatosis, Human Papilloma Virus | Unknown | Newcastle-upon-Tyne Hospitals NHS Trust | 400 | 2018-04-01 | 2022-01-11 |
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Herpes Simplex (25) · HIV Infections (20) · Herpes Genitalis (13) · Acquired Immunodeficiency Syndrome (12) · AIDS-Related Complex (7) · Herpes Labialis (6) · Herpesviridae Infections (5) · AIDS-Related Opportunistic Infections (4) · Communicable Diseases (4) · Herpes Zoster (4) · Immune System Diseases (4) · Infections (4) · Rare Diseases (4) · Virus Diseases (4) · Cytomegalovirus Infections (3)
National Institute of Allergy and Infectious Diseases (NIAID) (12) · University of Washington (7) · Glaxo Wellcome (5) · Genzyme, a Sanofi Company (4) · National Center for Research Resources (NCRR) (4) · EMS (3) · Fred Hutchinson Cancer Center (3) · Assiut University (2) · Centers for Disease Control and Prevention (2) · Medivir (2) · National Eye Institute (NEI) (2) · Sohag University (2) · University of Sao Paulo General Hospital (2) · Al-Azhar University (1) · Assistance Publique - Hôpitaux de Paris (1)
United States (42) · Canada (6) · France (6) · United Kingdom (6) · Brazil (5) · Egypt (5) · Germany (5) · Italy (5) · China (3) · Spain (3) · Australia (2) · Austria (2) · Belgium (2) · Israel (2) · Poland (2)
Anna Wald, MD, MPH (5) · Connie Celum, MD, MPH (4) · Corey L (2) · David W. Kimberlin (2) · Richard J. Whitley (2) · A-Dong Shen, Master (1) · A. D'jamali, MD, MS (1) · Adam Donne (1) · Aldo Lucchetti, MD (1) · Asode A Shetty, MD, PhD, MCh, FRCS (1) · Brian Hill, MD, PhD (1) · CA Benson (1)
PMID 21991950, PMID 22225814, PMID 39251561, PMID 16282339, PMID 1646585, PMID 18081360, PMID 18572080, PMID 18667923, PMID 18846389, PMID 19050195, PMID 19530940, PMID 19715417, PMID 19838129, PMID 20214474, PMID 20443734, PMID 20702659, PMID 20851499, PMID 21099672, PMID 21104007, PMID 21150554, PMID 21320979, PMID 21998479, PMID 22183840, PMID 22433279, PMID 23254142, PMID 24569417, PMID 25155587, PMID 25473327, PMID 25628457, PMID 25749169, PMID 25904747, PMID 26289222, PMID 26375604, PMID 2653790, PMID 26755499, PMID 27689547, PMID 28437539, PMID 29146146, PMID 29507070, PMID 29746903, PMID 29747074, PMID 2992899, PMID 30921087, PMID 30962334, PMID 31841577, PMID 32129861, PMID 33020163, PMID 37279999, PMID 38670599, PMID 38700045
2014 (2), 2016 (2), N01AI30025 (2), 2015 (1), 2017 (1), 2023 (1), K23AI071257 (1), P01AI030731 (1), P30CA012197 (1), R01AI050132 (1), R01AI052054 (1), U01AI047981 (1), U01AI052054 (1), U10CA031946 (1), U19AI031448 (1)