126 completed, 19 unknown, 13 terminated, 11 recruiting. 48 Phase 4, 42 Phase 1, 37 Phase 3, 33 Not applicable, 19 Phase 2.
Follow Pantoprazole: new trials by email Literature Review of Pantoprazole trials Research Report on Pantoprazole
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| This Randomized, Clinical Trial Evaluates the Efficacy of Oral Versus Sublingual Vitamin B12 Supplementation in Correcting Early-onset Vitamin B12 Deficiency in Adult Patients Using Proton Pump Inhibitors (PPIs). The Primary Outcome is the Change in Serum Vitamin B12 Levels Over a 6-week Cyanocobalamin 1000 Mcg Oral Tablet, Cyanocobalamin 1000 Mcg Sublingual Tablet, Proton Pump Inhibitor therapy only - Hypovitaminosis b 12 | Phase 3 | Not yet recruiting | Tanta University | 23 | 2026-12-30 | 2025-05-13 |
| A Study to Compare How CHF10196 (Florensocatib) is Absorbed Into the Blood When Given Alone and With a Drug That Reduces Stomach Acid in Healthy Male Participants CHF10196, Pantoprazole - Healthy Volunteers | Phase 1 | Not yet recruiting | Chiesi Farmaceutici S.p.A. | 18 | 2026-10-14 | 2026-07-06 |
| Keverprazan vs Pantoprazole for the Treatment of ANVUGIB Pantoprazole, Keverprazan - Non-variceal Upper Gastrointestinal Bleeding | Not applicable | Not yet recruiting | General Hospital of Shenyang Military Region | 908 | 2026-10-01 | 2026-08-20 |
| A Study of Navlimetostat (BMS-986504) Drug Interactions and Food Effect in Healthy Participants Navlimetostat, Itraconazole, Rifampin - Healthy Female Adults | Phase 1 | Recruiting | Bristol-Myers Squibb | 80 | 2026-08-31 | 2026-10-05 |
| Olanzapine Based Dexamethasone-sparing Regimen for Breast Cancer Patients With Metabolic-risk Factors Pantoprazole, olanzapine, Dexamethasone - Olanzapine, Breast Cancer | Not applicable | Recruiting | Alexandria University | 90 | 2026-05-10 | 2026-08-04 |
| Pantoprazole After Prophylactic Endoscopic Variceal Treatment Pantoprazole - Esophageal and Gastric Varices, Liver Cirrhosis | Not applicable | Enrolling by invitation | General Hospital of Shenyang Military Region | 208 | 2026-03-27 | 2026-04-01 |
| Post-Cardiac Surgery Acute Kidney Injury Prevention by Administration of Proton Pump Inhibitor (P2 Trial) Protonix (Pantoprazole) 40 mg q 12 hrs for 3 days, Pepcid (Famotidine) 20 mg q 12 hrs for 3 days - Acute Kidney Injury | Phase 2 | Recruiting | The University of Texas Health Science Center, Houston | 400 | 2025-01-24 | 2025-05-14 |
| PPIs and In-Hospital Morbidity in Acute Variceal Bleeding With Chronic Liver Disease Omeprazole 40 mg IV, pantoprazole 40 mg iv - Morbidity | Phase 2 | Recruiting | Universidad Autonoma de Nuevo Leon | 60 | 2024-10-20 | 2026-06-12 |
| Comparison of Early Proton Pump Inhibitor Initiation Versus Usual Care on Acute Kidney Injury in Hemorrhagic Shock Patients Protonix (Pantoprazole) 40 mg q 12 hrs for 2 days, Protonix (pantoprazole) 40 mg q 24 hrs for 2 days - Acute Kidney Injury | Phase 2 / Phase 3 | Recruiting | The University of Texas Health Science Center, Houston | 100 | 2024-09-07 | 2026-02-19 |
| Clinical Trial for the Comparative Evaluation of Acid Suppression and Symptom Management of Gastroesophageal Reflux Disease With the Administration of Tegoprazan or Pantoprazole Tegoprazan, Pantoprazole - Gastroesophageal Reflux Disease | Phase 4 | Recruiting | Carnot Laboratories | 128 | 2024-07-30 | 2025-07-23 |
| A Study to Evaluate BMS-986470 in Healthy Volunteers and Participants With Sickle Cell Disease BMS-986470, Placebo, Famotidine - Anemia, Sickle Cell, Healthy Volunteers | Phase 1 / Phase 2 | Recruiting | Bristol-Myers Squibb | 224 | 2024-07-17 | 2026-08-18 |
| The Role of Coenzyme Q10 in the Prophylaxis of Oxaliplatin Induced Peripheral Neuropathy in Patients With Colorectal Cancer Coenzyme Q10, Oxaliplatin, 5-Fluorouracil (5-FU) - Colorectal Cancer | Phase 1 | Recruiting | toqa saad mohammed mohammed | 22 | 2024-06-01 | 2025-03-04 |
| Prevention of Post-Cardiac Surgery Acute Kidney Injury by Proton Pump Inhibitor Pantoprazole, Famotidine - Acute Kidney Injury | Phase 2 | Completed | The University of Texas Health Science Center, Houston | 100 | 2024-01-10 | 2026-03-10 |
| Efficacy of Vonoprazan in Eradication of Resistant Strain of Helicobacter Pylori Vonoprazan, Amoxicillin and Levofloxacin, Pantoprazole 40mg, Amoxicillin and Levofloxacin - Helicobacter Pylori Infection | Phase 3 | Completed | Ain Shams University | 320 | 2023-10-12 | 2024-05-16 |
| Efficacy of Proton Pump Inhibitors in Cirrhotic Patients With Acute Variceal Bleeding Proton Pump Inhibitors, No Proton Pump Inhibitors - Upper Gastrointestinal Hemorrhage | Phase 4 | Not yet recruiting | West China Hospital | 672 | 2023-10-01 | 2023-09-28 |
| Baduanjin Program Effect on Geriatric Functional Dyspepsia baduinjuin activities, pantoprazole - Functional Dyspepsia | Not applicable | Unknown | Cairo University | 40 | 2023-07-20 | 2023-06-23 |
| The Effect of Dual Eradication Therapy vs PPI on Gastrointestinal Bleeding in ACS Patients Vonoprazan-based dual eradication therapy for two weeks, amoxicillin, Pantoprazole - Acute Coronary Syndrome, Helicobacter Pylori Infection | Phase 4 | Recruiting | Qilu Hospital of Shandong University | 2600 | 2023-04-12 | 2025-09-16 |
| Preoperative Use of Pantoprazole for Prevention of Post Operative Nausea and Vomiting in Gynecologic Surgery pantoprazole, Placebo - Postoperative Nausea and Vomiting | Phase 2 | Recruiting | United States Naval Medical Center, Portsmouth | 132 | 2022-08-26 | 2025-05-21 |
| Efficacy and Safety of Thread Embedding Acupuncture in Treating Gastroesophageal Reflux Disease Thread embedding acupuncture, Pantoprazole 40mg - Gastroesophageal Reflux | Not applicable | Completed | University of Medicine and Pharmacy at Ho Chi Minh City | 66 | 2022-05-04 | 2022-07-28 |
| Role of Proton Pump Inhibitors on the Postoperative Course Following Pancreaticoduodenectomy Placebo, Pantoprazole - Pancreatic Cancer, Pancreas Cancer | Phase 2 | Terminated | Washington University School of Medicine | 56 | 2022-04-21 | 2025-05-06 |
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Gastroesophageal Reflux (40) · Gastrointestinal Hemorrhage (8) · Peptic Ulcer (8) · Dyspepsia (5) · Heartburn (5) · Non-Erosive Reflux Disease (5) · Peptic Ulcer Hemorrhage (5) · Acute Kidney Injury (4) · Ulcer (4) · Acute Coronary Syndrome (3) · Coronary Artery Disease (3) · Esophagitis (3) · Hemorrhage (3) · Neoplasms (3) · Pneumonia (3)
Boehringer Ingelheim (13) · Wyeth is now a wholly owned subsidiary of Pfizer (9) · Kaohsiung Veterans General Hospital. (8) · Takeda (8) · Nycomed (5) · AstraZeneca (3) · McMaster University (3) · National Taiwan University Hospital (3) · Seoul National University Hospital (3) · The University of Texas Health Science Center, Houston (3) · Alexandria University (2) · Asan Medical Center (2) · Assiut University (2) · Bristol-Myers Squibb (2) · Children's Mercy Hospital Kansas City (2)
United States (45) · Canada (18) · Germany (18) · South Korea (14) · Taiwan (13) · Italy (10) · India (8) · Netherlands (8) · Australia (7) · Belgium (7) · China (7) · Denmark (7) · Poland (7) · Switzerland (7) · United Kingdom (7)
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