27 completed, 9 unknown, 3 recruiting, 3 terminated. 14 Phase 3, 14 Phase 4, 7 Not applicable, 4 Phase 2, 3 Phase 1.
Follow Ofloxacin: new trials by email Literature Review of Ofloxacin trials Research Report on Ofloxacin
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Early Discontinuation of Antibiotics in Paediatric High-risk Febrile Neutropenia Early Discontinuation of Antibiotics, Standard Antibiotic Continuation Strategy - Febrile Neutropenia (FN), Pediatric Cancer | Phase 4 | Not yet recruiting | Hospital Universitari Vall d'Hebron Research Institute | 136 | 2026-06-01 | 2026-05-15 |
| Intralesional Injection of Levofloxacin for the Management of Cutaneous Leishmaniasis Levofloxacin 0.5% - Cutaneous Leishmaniasis | Phase 2 | Recruiting | Hayder Adnan Fawzi | 40 | 2025-02-09 | 2025-09-30 |
| Feasibility Study of the Proposed Test-and-treat Screening Program in Younger Participants With H. Pylori Infection Bismuth Subcitrate, Esomeprazole, Metronidazole - Helicobacter Pylori Infection | Unknown | National Institute of Public Health, Slovenia | 2000 | 2024-02-01 | 2024-02-09 | |
| Levofloxacin Concomitant Versus Levofloxacin Sequential sequential, Levofloxacin 500Mg Oral Tablet - Helicobacter Pylori Infection | Phase 4 | Not yet recruiting | Damascus Hospital | 150 | 2024-01-02 | 2023-10-03 |
| Efficacy of Vonoprazan in Eradication of Resistant Strain of Helicobacter Pylori Vonoprazan, Amoxicillin and Levofloxacin, Pantoprazole 40mg, Amoxicillin and Levofloxacin - Helicobacter Pylori Infection | Phase 3 | Completed | Ain Shams University | 320 | 2023-10-12 | 2024-05-16 |
| Absorption of Antibiotics With High Oral Bioavailability in Short-bowel Syndrome Amoxicillin, Levofloxacin, Ofloxacin - Short Bowel Syndrome, Infection, Bacterial | Phase 1 | Unknown | Central Hospital, Nancy, France | 10 | 2022-12-09 | 2024-08-29 |
| Diagnostics of Chronic Endometritis in Infertility Ofloxacin + Metronidazole - Infertility Unexplained, Abnormal Uterine Bleeding | Not applicable | Completed | Jagiellonian University | 102 | 2021-04-01 | 2025-04-18 |
| LOAD VS Levofloxacine Concomitant Doxycycline, Levofloxacin 500mg - Helicobacter Pylori Infection | Phase 4 | Unknown | Damascus Hospital | 80 | 2020-10-31 | 2020-11-12 |
| Prophylactic Antibiotics for Urinary Tract Infections After Robot-Assisted Radical Cystectomy Clindamycin, Diary, Ertapenem - Bladder Carcinoma, Refractory Bladder Carcinoma | Phase 4 | Completed | Roswell Park Cancer Institute | 89 | 2020-09-02 | 2026-09-29 |
| Ofloxacin Concentration-toxicity Relationship in the Elderly ofloxacin, questionnaire, Ofloxacin Serum concentration - Ofloxacin, Bone and Joint Infection | Not applicable | Recruiting | Centre Hospitalier Universitaire, Amiens | 110 | 2020-06-02 | 2025-06-10 |
| Prospective Randomised Trial of First and Second Line Treatments of RCT of First and Second Line H Pylori Treatments in Slovenia Esomeprazole 40mg, Clarithromycin 500 mg, Metronidazole 400 mg,, Esomeprazole 40mg, Bismuth subcitrate 120 mg, Amoxicillin 500 mg, Metronidazole 400 mg, Esomeprazole 40mg, Amoxicillin 500 mg, Levofloxacin 500 mg - Helicobacter Pylori Infection, Eradication Treatments | Not applicable | Unknown | Slovenian Society for Gastroenterology and Hepatology | 560 | 2020-05-10 | 2020-04-24 |
| Pilocarpine After Combined Cataract/Trabectome Surgery Pilocarpine, Ofloxacin, Prednisolone - Open Angle Glaucoma, Ocular Hypertension | Phase 3 | Withdrawn | Montefiore Medical Center | 2019-06-05 | 2022-04-07 | |
| Does Topical Otic Drop Use at Time of Tympanostomy Tube Surgery Improve Outcomes When no Middle Ear Effusion is Present Ofloxacin otic solution - Otitis Media | Phase 4 | Terminated | Boston Children's Hospital | 9 | 2019-05-16 | 2026-09-14 |
| Pilocarpine Use After Kahook Goniotomy Pilocarpine, Prednisolone, Ofloxacin - Glaucoma | Phase 3 | Recruiting | Montefiore Medical Center | 142 | 2019-05-01 | 2025-11-10 |
| Tedizolid Prolonged Treatment for Prosthetic Joint Infections Tedizolid Phosphate 200 MG [Sivextro] - Prosthetic Joint Infection | Not applicable | Completed | Tourcoing Hospital | 35 | 2018-08-28 | 2021-09-08 |
| Phase 3 Multicenter Randomized Double Blind Placebo Controlled Study With Antibacterial Prophylaxis in Azacitidine Treated MDS Patients Levofloxacin, Placebo Oral Tablet - Prevention | Phase 3 | Completed | Sheba Medical Center | 67 | 2017-08-01 | 2023-11-27 |
| Alternative Antibiotic Regimen in Periodontitis Treatment Ofloxacin, Amoxicillin, Metronidazole - Amoxicillin, Metronidazole | Phase 4 | Completed | Istanbul Medipol University Hospital | 74 | 2017-04-01 | 2020-04-20 |
| Solifenacin, Levofloxacin or Lornoxicam, Which Is Ideal for Management of Intravesical Instillation BCG Side Effects? sofenacin, Tavanic, Xefo - Non-Muscle-invasive Bladder Cancer (NMIBC), Bacillus Calmette-Guerin (BCG) Cystitis | Phase 4 | Unknown | Mansoura University | 150 | 2017-02-01 | 2017-05-23 |
| Healthy Patients & Effect of Antibiotics Levofloxacin, Azithromycin, Cefpodoxime - Microbiota, Anti-bacterial Agents | Not applicable | Completed | Washington University School of Medicine | 20 | 2017-01-01 | 2022-11-10 |
| Efficacy and Safety of Nemonoxacin vs Levofloxacin in Adult Patients With Community-Acquired Pneumonia Nemonoxacin, Tavanic, Placebo (250 ml) - Pneumonia, Bacterial | Phase 3 | Completed | R-Pharm | 342 | 2016-05-04 | 2023-02-16 |
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Infections (4) · Diabetes Mellitus (3) · Diabetic Foot (3) · Ulcer (3) · Cataract (2) · Community-Acquired Pneumonia (2) · Drug-Related Side Effects and Adverse Reactions (2) · Otitis Media (2) · Pelvic Inflammatory Disease (2) · Urinary Bladder Neoplasms (2) · Urinary Tract Infections (2) · Arthritis, Reactive (1) · Bacterial Infections (1) · Communicable Diseases (1) · Corneal Diseases (1)
Abeona Therapeutics, Inc (2) · Assistance Publique - Hôpitaux de Paris (2) · Damascus Hospital (2) · Montefiore Medical Center (2) · Ain Shams University (1) · Alcon Research (1) · Asofarma de México S.A de C.V. (1) · Bayer (1) · Boston Children's Hospital (1) · Boston University (1) · Central Hospital, Nancy, France (1) · Centre Hospitalier Universitaire, Amiens (1) · Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (1) · Gary Morrow (1) · Gruppo Italiano Malattie EMatologiche dell'Adulto (1)
United States (14) · France (7) · South Africa (4) · Egypt (3) · Finland (2) · Israel (2) · Italy (2) · Peru (2) · Poland (2) · Russia (2) · Slovenia (2) · Spain (2) · Syria (2) · Turkey (Türkiye) (2) · United Kingdom (2)
Marouf M Alhalabi, MD (2) · Paul Litka, MD (2) · Ahmed Elhussein, MBBCH (1) · Ahmed Elkarta, MBBCH (1) · Ahmed Mosbah, MD (1) · Bruno BL Laviolle, MD/PhD (1) · Charles Lin, MD (1) · Charles R Horsburgh, MD (1) · Claire Pomeroy, MD (1)
PMID 18990064, PMID 14986270, PMID 15276398, PMID 15329363, PMID 15530127, PMID 1559306, PMID 15840453, PMID 16236878, PMID 16470119, PMID 16982292, PMID 16988514, PMID 18211932, PMID 18366444, PMID 18795962, PMID 18818959, PMID 18989231, PMID 19588358, PMID 20002783, PMID 20094812, PMID 20176900, PMID 20215625, PMID 20601657, PMID 20632458, PMID 20675299, PMID 20716255, PMID 20729232, PMID 21283017, PMID 22083071, PMID 22129166, PMID 22157324, PMID 22530208, PMID 22659765, PMID 2292168, PMID 23305215, PMID 23392467, PMID 23398868, PMID 23499151, PMID 23926058, PMID 23988422, PMID 24667978, PMID 25135090, PMID 25139552, PMID 25162818, PMID 25261418, PMID 25331703, PMID 25407158, PMID 25650692, PMID 25950206, PMID 25959631, PMID 26202768
2014 (1), 2017 (1), U01AI100805 (1), U10CA037420 (1)