30 completed, 6 terminated, 4 unknown, 2 suspended. 46 Phase 3, 6 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 46 | Completed 30, Terminated 6, Unknown 4, Suspended 2, Withdrawn 2, Not yet recruiting 1, Recruiting 1 |
| Phase 2 | 6 | Completed 3, Recruiting 1, Suspended 1, Terminated 1 |
Follow Ulcer: new trials by email Literature Review of Ulcer trials Research Report on Ulcer
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Comparison of Rabeprazole and Vonoprazan in the Prevention of Post-endoscopic Variceal Ligation Ulcer in Patients With Cirrhosis Vonoprazan, Rabeprazol - Endoscopic Variceal Band Ligation | Phase 3 | Not yet recruiting | King George's Medical University | 300 | 2026-05-01 | 2026-05-27 |
| Efficacy and Safety of Different Initial Doses of Oral Propranolol in the Treatment of Ulcerated Infantile Hemangioma propranolol - Infantile Hemangioma | Phase 2 / Phase 3 | Recruiting | West China Hospital | 32 | 2025-01-01 | 2026-09-21 |
| A Prospective Study on the Therapeutic Outcomes of Mebo and Tantum Verde in Patients With Oral Mucositis MEBO Wound Ointment (MEBO), Tantum Verde® mouthwash - Oral Mucositis (Ulcerative) Due to Radiation | Phase 3 | Completed | Cairo University | 36 | 2023-03-01 | 2025-09-22 |
| Safety and Efficacy Study Using Gene Therapy for Critical Limb Ischemia (NL003-CLI-III-2) NL003, Normal Saline - Arterial Occlusive Disease, Ischemia | Phase 3 | Completed | Beijing Northland Biotech. Co., Ltd. | 242 | 2019-08-28 | 2024-09-20 |
| Safety and Efficacy Study Using Gene Therapy for Critical Limb Ischemia (NL003-CLI-III-1) NL003, Normal Saline - Arterial Occlusive Disease, Ischemia | Phase 3 | Completed | Beijing Northland Biotech. Co., Ltd. | 302 | 2019-08-02 | 2024-09-19 |
| To Evaluate Efficacy and Long-term Safety of Ozanimod in Japanese Subjects With Moderately to Severely Active Ulcerative Colitis Ozanimod, Placebo - Colitis, Ulcerative | Phase 3 | Completed | Celgene | 198 | 2019-06-03 | 2025-10-15 |
| Randomized Trial of Curcumin to Reduce Mucositis in Autologous Transplant Setting Curcumin Lozenges, Placebo Lozenges - Oral Mucositis (Ulcerative) | Phase 3 | Unknown | Tata Memorial Centre | 190 | 2018-12-16 | 2023-11-24 |
| Efficacy of Ulinastatin for Reducing Radiation-Induced Oral Mucositis in Nasopharyngeal Carcinoma Patients Cisplatin, Intensity Modulated Radiation Therapy, Ulinastatin - Oral Mucositis (Ulcerative) Due to Radiation | Phase 3 | Completed | Sun Yat-sen University | 179 | 2018-01-30 | 2026-05-07 |
| A Study Assessing the Efficacy and Safety of Adalimumab in Active Ulcer(s) of Pyoderma Gangrenosum in Participants in Japan adalimumab - Pyoderma Gangrenosum | Phase 3 | Completed | AbbVie | 22 | 2017-10-27 | 2021-03-09 |
| Mycotic Antimicrobial Localized Injection for Treatment of Corneal Ulcers Intrastromal voriconazole, Natamycin - Corneal Ulcer, Fungal Keratitis | Phase 3 | Completed | University of California, San Francisco | 70 | 2016-09-01 | 2025-09-25 |
| A Study to Investigate the Safety and Efficacy of LT-02 in Patients With Mesalamine Refractory Ulcerative Colitis (UC) LT-02, LT-02 Placebo - Ulcerative Colitis | Phase 3 | Terminated | Prometheus Laboratories | 25 | 2016-07-01 | 2017-06-15 |
| Cross-linking for Corneal Ulcers Treatment Trial Corneal Cross-linking, Anti Fungal Drug - Corneal Ulcer, Infectious Keratitis | Phase 3 | Completed | University of California, San Francisco | 147 | 2015-11-01 | 2025-06-18 |
| Clinical Efficacy of Platelet Gel From Cord Blood for the Treatment of Diabetic Foot Ulcers Allogeneic cord blood platelet gel-CBPG, Standard Local Medications-SLM - Diabetic Foot Ulcers | Phase 3 | Completed | Centro Nazionale Sangue | 50 | 2015-01-01 | 2017-07-21 |
| PRP ULCERAS: Clinical Trial Phase III Platelet-Rich Plasma, Usual treatment - Ulcer | Phase 3 | Withdrawn | Basque Health Service | 2015-01-01 | 2020-02-25 | |
| A Comparative Study of the Healing of Chronic Ulcers of Recessive Epidermolysis Bullosa : Dressing vs Amniotic Membrane Amniotic Membrane - Epidermolysis Bullosa Dystrophica, Recessive, Ulcer | Phase 3 | Unknown | Assistance Publique - Hôpitaux de Paris | 22 | 2015-01-01 | 2016-11-04 |
| Safety and Efficacy Trial of HP802-247 in the Treatment of Chronic Venous Leg Ulcers HP802-247, HP802-247 Vehicle - Venous Ulcer, Venous Stasis Ulcer | Phase 3 | Terminated | Healthpoint | 252 | 2013-11-01 | 2016-10-03 |
| Efficacy & Safety of Pedyphar Ointment in Diabetic Foot Ulcer Treatment Pedyphar Ointment, Panthenol - Diabetic Foot Ulcer | Phase 3 | Completed | European Egyptian Pharmaceutical Industries | 80 | 2013-04-01 | 2015-03-05 |
| Evaluate Misoprostol for the Healing of Small Bowel Ulcers in Low-dose Aspirin Users Complicated by Small Bowel Bleeding Misoprostol, Placebo - Ulcer Hemorrhage | Phase 2 / Phase 3 | Completed | Chinese University of Hong Kong | 82 | 2013-04-01 | 2019-01-31 |
| A Comparison of the dermaPACE® (Pulsed Acoustic Cellular Expression) Device in Conjunction With Standard of Care Versus Standard of Care Alone in the Treatment of Diabetic Foot Ulcers Electrohydraulic-generated shock wave, Sham device plus standard of care - Diabetic Foot Ulcers | Phase 3 | Unknown | SANUWAVE, Inc. | 90 | 2013-03-01 | 2014-03-06 |
| Study Investigating the Safety and Efficacy of HP802-247 in the Treatment of Venous Leg Ulcers >12 cm2 to ≤ 36 cm2 HP802-247, Vehicle - Venous Leg Ulcers | Phase 3 | Completed | Healthpoint | 155 | 2012-11-01 | 2017-07-26 |
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Diabetic Foot (10) · Colitis (7) · Colitis, Ulcerative (7) · Gastrointestinal Diseases (6) · Colonic Diseases (5) · Diabetes Mellitus (5) · Inflammatory Bowel Diseases (5) · Digestive System Diseases (4) · Gastroenteritis (4) · Intestinal Diseases (4) · Pathologic Processes (4) · Proctitis (4) · Proctocolitis (4) · Varicose Ulcer (4)
Pathological Conditions, Signs and Symptoms (46) · Pathologic Processes (42) · Skin and Connective Tissue Diseases (21) · Skin Diseases (19) · Cardiovascular Diseases (16) · Vascular Diseases (16) · Skin Ulcer (15) · Leg Ulcer (14) · Diabetes Complications (10) · Diabetic Angiopathies (10) · Endocrine System Diseases (10) · Foot Ulcer (10) · Diabetic Neuropathies (9) · Digestive System Diseases (9) · Gastrointestinal Diseases (7)
Mesalamine (3) · Budesonide (2) · Ibuprofen (2) · Ofloxacin (2) · Saline Solution (2) · pexiganan (2) · 1-(5-(2-fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl)-N-methylmethanamine (1) · Acyclovir (1) · Adalimumab (1) · Amoxicillin-Potassium Clavulanate Combination (1) · Biological Dressings (1) · Calcium Dobesilate (1) · Cisplatin (1) · Collagenases (1) · Corneal Cross-Linking (1)
Bausch Health Americas, Inc. (3) · Healthpoint (3) · Abeona Therapeutics, Inc (2) · Amgen (2) · Beijing Northland Biotech. Co., Ltd. (2) · University of California, San Francisco (2) · AbbVie (1) · Actelion (1) · Assistance Publique - Hôpitaux de Paris (1) · Azidus Brasil (1) · Basque Health Service (1) · Bayer (1) · BioSyntech Canada Inc. (1) · Cairo University (1) · Celgene (1)
United States (17) · Canada (6) · China (5) · India (5) · Poland (5) · Spain (5) · France (3) · Germany (3) · Hungary (3) · Italy (3) · Japan (3) · Russia (3) · Belgium (2) · Bulgaria (2) · Colombia (2)
Tommy Lee, MSHS (3) · Herbert B Slade, MD (2) · Paul Litka, MD (2) · Robert Kirsner, MD (2) · William Marston, MD (2) · Alberto Restrepo, M.D. (1) · Arturo Orduz, MD (1) · Barbara Latenser, MD (1)
PMID 29037354, PMID 18990064, PMID 25644096, PMID 26165391, PMID 27416045, PMID 11396765, PMID 15504999, PMID 17897470, PMID 18601587, PMID 19064169, PMID 19128245, PMID 19152653, PMID 19170984, PMID 19424751, PMID 19715417, PMID 20074379, PMID 20443734, PMID 20873963, PMID 21155009, PMID 21896561, PMID 21947706, PMID 23180507, PMID 23736928, PMID 2403699, PMID 25547983, PMID 25583938, PMID 25951490, PMID 25995322, PMID 27163986, PMID 28614248, PMID 29739175, PMID 29966612, PMID 30944817, PMID 31619359, PMID 31786695, PMID 32088712, PMID 32289853, PMID 32557558, PMID 33031809, PMID 33079921, PMID 33141449, PMID 35024776, PMID 35044972, PMID 35120736, PMID 3753059, PMID 37975046, PMID 42427283
2014 (1)