11 completed, 3 terminated, 2 unknown, 1 enrolling by invitation. 18 Phase 1, 8 Phase 2.
Follow Ulcer: new trials by email Literature Review of Ulcer trials Research Report on Ulcer
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Evaluating Autologous Platelet-Rich Fibrin Plasma for Chronic Diabetic Foot Ulcers PRFM, Standard of Care (SoC) - Diabetic Foot Ulcer (DFU), Ulcer | Phase 1 / Phase 2 | Not yet recruiting | Tiger Biosciences, LLC. | 55 | 2026-09-01 | 2026-09-25 |
| Seaweed Extract (Fucoidan) for Gut Inflammation in Ulcerative Colitis Low molecular weight fucoidan and standard care, Placebo and standard of care - Ulcerative Colitis (UC) | Phase 1 / Phase 2 | Enrolling by invitation | Allama Iqbal Medical College | 90 | 2026-08-01 | 2026-08-26 |
| Safety and Preliminary Efficacy of Allogeneic Endothelial Progenitor Cells (EPCs) in Patients With Critical Limb Ischemia EPCs, Clinical standard treatment (CST) - Critical Limb Ischemia | Phase 1 | Unknown | Allife Medical Science and Technology Co., Ltd. | 27 | 2024-04-01 | 2024-04-11 |
| Evaluating Chinese Medicine Oral Rinse for Irradiated Oral Mucositis in Head & Neck Cancer Patients Chinese Medicine Oral Rinse Formula-I (CMORF-I), Standard Care, Placebo - Head and Neck Neoplasms, Oral Mucositis (Ulcerative) Due to Radiation | Phase 1 / Phase 2 | Unknown | Chinese University of Hong Kong | 40 | 2023-01-31 | 2022-12-27 |
| Nitric Oxide Generating Gel Dressing in Patients With Diabetic Foot Ulcers NOx dressing, Standard of Care - Diabetic Foot Ulcer | Phase 1 / Phase 2 | Completed | Edixomed Ltd | 130 | 2013-06-01 | 2016-01-20 |
| Comparative Bioavailability Study of Two Test Products of Fixed Dose Combination Capsule of Acetylsalicylic Acid (ASA) and Pantoprazole (Each Capsule Contains ASA 100 mg and Pantoprazole 20 mg) Under Fed Conditions Test 1= ASA 100 mg and pantoprazole 20 mg capsule formulation one, Test 2= ASA 100 mg and pantoprazole 20 mg capsule formulation two, ASA 100 mg tablet - Ulcers, Duodenal and Gastric | Phase 1 | Completed | GlaxoSmithKline | 24 | 2013-05-16 | 2017-07-13 |
| Comparative Bioavailability Study of Two Test Products of Fixed Dose Combination Capsule of ASA (Acetylsalicylic Acid) and Pantoprazole (Each Capsule Contains ASA 100 mg and Pantoprazole 20 mg) Under Fasting Conditions Test 1= ASA 100 mg and pantoprazole 20 mg capsule formulation one, Test 2= ASA 100 mg and pantoprazole 20 mg capsule formulation two, ASA 100 mg tablet - Ulcers, Duodenal and Gastric | Phase 1 | Completed | GlaxoSmithKline | 24 | 2013-05-14 | 2017-07-13 |
| The Effect of the Cosmetic Cream NMBM on Leg Ulcers - a Pilot Study NMBM, Compression garments - Ulcer, Venous Ulcer | Phase 1 / Phase 2 | Completed | M.D. Lederman Consulting Ltd | 30 | 2013-02-01 | 2017-01-11 |
| Pharmacokinetics of Diammine Silver Fluoride DIammine SIlver Fluoride - Fluoride and Silver Pharmacokinetics of DSF Applied Topically to Teeth of Adults. Erythema, Bleeding, White Changes, Ulceration and Pigmentation Were Assessed | Phase 1 | Completed | Universidad Peruana Cayetano Heredia | 6 | 2011-07-01 | 2012-08-14 |
| The ASCEND Study: A Study to Investigate the Safety and Clinical Effect of Nexagon to Treat Slow Healing Diabetic Foot Ulcers Nexagon®, Nexagon® vehicle - Diabetic Foot Ulcer | Phase 1 / Phase 2 | Terminated | OcuNexus Therapeutics, Inc. | 24 | 2009-04-01 | 2010-08-31 |
| Study to Evaluate Bone Marrow Cells in the Treatment of Chronic Wounds Bone Marrow Aspirate, Cultured Bone Marrow Cells, Control - Ulcer | Phase 1 | Terminated | Dr. E.Badiavas | 11 | 2008-07-01 | 2018-04-30 |
| Study Comparing a Fixed-Dose Capsule of Esomeprazole 40mg and LDA 325mg With Free Combination Esomeprazole 40mg/ASA 325mg, Esomeprazole, ASA - Ulcers, Upper GI Symptoms | Phase 1 | Completed | AstraZeneca | 84 | 2008-04-01 | 2009-03-12 |
| FGF-1 for Topical Administration for the Treatment of Diabetic or Venous Stasis Ulcers FGF-1 - Chronic Wounds, Diabetes | Phase 1 | Completed | Venturis Therapeutics, Inc. | 8 | 2005-09-02 | 2026-08-19 |
| Stem Cell Study for Patients With Leg Ulcer/Gangrene Autologous peripheral blood CD34 positive cell therapy - Leg Pain, Ulcer | Phase 1 / Phase 2 | Completed | Translational Research Center for Medical Innovation, Kobe, Hyogo, Japan | 15 | 2003-11-01 | 2009-02-09 |
| Gene Therapy to Improve Wound Healing in Patients With Diabetes GAM501 - Wounds and Injuries, Diabetes | Phase 1 | Completed | Tissue Repair Company | 21 | 2002-08-01 | 2007-11-20 |
| Morphine Gel for Bedsores Pain relief for pressure ulcers - Decubitus Ulcer | Phase 1 / Phase 2 | Completed | University of Kansas | 75 | 2000-03-01 | 2013-05-20 |
| Safety and Tolerability of the Vaginal Gel PRO 2000/5 PRO 2000 - HIV Infections | Phase 1 | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 60 | 2008-07-30 | |
| Study Evaluating rhIL-11 in Left-Sided Ulcerative Colitis rhIL-11 - Ulcerative Colitis, Inflammatory Bowel Disease | Phase 1 | Terminated | Wyeth is now a wholly owned subsidiary of Pfizer | 2006-05-18 |
Diabetic Foot (4) · Colitis (2) · Colitis, Ulcerative (2) · Diabetes Mellitus (2) · Pain (2) · Peripheral Vascular Diseases (2) · Varicose Ulcer (2) · Adenoviridae Infections (1) · Agnosia (1) · Bronchiolitis Obliterans Syndrome (1) · Chronic Limb-Threatening Ischemia (1) · Gangrene (1) · HIV Infections (1) · HIV Seropositivity (1)
Pathologic Processes (18) · Pathological Conditions, Signs and Symptoms (18) · Cardiovascular Diseases (8) · Skin Diseases (7) · Skin and Connective Tissue Diseases (7) · Vascular Diseases (7) · Skin Ulcer (6) · Endocrine System Diseases (5) · Leg Ulcer (5) · Diabetes Complications (4) · Diabetic Angiopathies (4) · Diabetic Neuropathies (4) · Foot Ulcer (4) · Diabetes Mellitus (3) · Arterial Occlusive Diseases (2)
Standard of Care (5) · Pantoprazole (2) · Tablets (2) · Tablets, Enteric-Coated (2) · Analgesia (1) · Aspirin (1) · Esomeprazole (1) · Fibroblast Growth Factor 1 (1) · Hydrogen (1) · PRO 2000 (1) · oprelvekin (1)
GlaxoSmithKline (2) · Allama Iqbal Medical College (1) · Allife Medical Science and Technology Co., Ltd. (1) · AstraZeneca (1) · Chinese University of Hong Kong (1) · Dr. E.Badiavas (1) · Edixomed Ltd (1) · M.D. Lederman Consulting Ltd (1) · National Institute of Allergy and Infectious Diseases (NIAID) (1) · OcuNexus Therapeutics, Inc. (1) · Tiger Biosciences, LLC. (1) · Tissue Repair Company (1) · Translational Research Center for Medical Innovation, Kobe, Hyogo, Japan (1) · Universidad Peruana Cayetano Heredia (1) · University of Kansas (1)
United States (4) · India (2) · China (1) · Hong Kong (1) · Israel (1) · Japan (1) · New Zealand (1) · Pakistan (1) · Peru (1) · United Kingdom (1)
Arthur Tucker, PhD (1) · Barbara Sosnowski, PhD (1) · Christopher Billings ., D.O (1) · Elsa Vasquez, DDS (1) · Evangelos V Badiavas, MD, PhD (1) · Jorge Castillo, DDS MSD PhD (1) · Ken Mayer (1) · Peter Milgrom, DDS (1) · Rozina Shahadat Khan, MBBS, M.PHIL,MSPH, CHPE,PHDHND (1) · Salim Abdool Karim (1) · Shoshana Greenberger, MD PhD (1)
PMID 11240232, PMID 15108222, PMID 15159012, PMID 15287078, PMID 16004814, PMID 16415901, PMID 16884839, PMID 16950583, PMID 18407446, PMID 18485252, PMID 18973181, PMID 19711453, PMID 20668585, PMID 21864666, PMID 22114446, PMID 22877866, PMID 22923859, PMID 23046006, PMID 23052923, PMID 23272643, PMID 23469127, PMID 23685937, PMID 24311846, PMID 24471119, PMID 25052044, PMID 25272640, PMID 25497988, PMID 25562805, PMID 25858507, PMID 26257818, PMID 27301877, PMID 27469197, PMID 27865796, PMID 28590441, PMID 30117204, PMID 31030097, PMID 31736742, PMID 32056010, PMID 32106571, PMID 32148535, PMID 32206048, PMID 32431180, PMID 32457762, PMID 32733583, PMID 32786044, PMID 32938944, PMID 32975375, PMID 33317592, PMID 33338592, PMID 33346027
R01AG027874 (1), R01AR045506 (1), R44AR046154 (1)