79 completed, 32 recruiting, 25 unknown, 3 active not recruiting. 53 Not applicable, 25 Phase 2, 11 Phase 3, 10 Phase 1, 10 Phase 4.
Follow Tremor: new trials by email Literature Review of Tremor trials Research Report on Tremor
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Basket Clinical Study to Assess Glycerol Tributyrate in Patients With Mitochondrial Encephalopathy, Lactic Acidosis, Stroke-like Episodes (MELAS) or Leber's Hereditary Optic Neuropathy-Plus (LHON-Plus) Glycerol Tributyrate - MELAS Syndrome, Lebers Hereditory Optic Neuropathy With Extra Ocular Symptoms (LHON-Plus) | Phase 1 / Phase 2 | Not yet recruiting | George Washington University | 24 | 2027-03-01 | 2026-10-05 |
| Wearable for Assessing Tremor and Continuous Health in Parkinson's Disease and Essential Tremor Device exposure: Wearable inertial sensor monitoring - PARKINSON DISEASE (Disorder) | Recruiting | Heriot-Watt University | 60 | 2026-11-01 | 2026-10-09 | |
| A Study to Evaluate the Efficacy, PK, Safety, and Tolerability of VIM0423 in Adults With Parkinson's Disease Tremor Insufficiently Responsive to Dopaminergic Therapy VIM0423, VIM0423 Placebo - PARKINSON DISEASE (Disorder) | Phase 2 | Recruiting | Vima Therapeutics | 80 | 2026-09-15 | 2026-11-10 |
| Comparison of Benzhexol and Procyclidine for Tremor in Tremor-Predominant Parkinson's Disease Benzhexol, Procyclidine - Parkinson Disease (PD) | Not applicable | Recruiting | safia bano | 88 | 2026-09-01 | 2026-09-14 |
| Effects of Targeted Temporal Interference Stimulation of Cerebellar Nuclei on Tremor and Gait Disturbance in Parkinson's Disease Patients Sham Temporal Interference Stimulation, Real Temporal Interference Stimulation - Parkinson's Disease, Movement Disorders | Not applicable | Not yet recruiting | YangPan | 50 | 2026-08-19 | 2026-06-10 |
| Effects of Transcutaneous Vagus Nerve Stimulation in Parkinson´s Disease Transcutaneous Electrical Nerve Stimulation (TENS) of Vagus Nerve, Conventional Physical therapy, Conventional Speech Therapy - Transcutaneous Vagal Nerve Stimulation (tVNS), Parkinson Disease (PD) | Not applicable | Active not recruiting | Universidade da Coruña | 46 | 2026-05-25 | 2026-08-07 |
| Open Label Study for the Use of Low Intensity Focused Ultrasound for Essential Tremor Low Intensity Focused Ultrasound (LIFU) - Essential Tremor | Early Phase 1 | Recruiting | University of California, Los Angeles | 20 | 2026-05-01 | 2026-05-20 |
| Neurocognitive Function Changes With Extended-Release Tacrolimus Among Older Kidney Transplant Recipients Conversion to extended-release tacrolimus, Maintenance of immediate-release tacrolimus - Kidney Transplant Recipients, Old Age | Phase 4 | Recruiting | Massachusetts General Hospital | 92 | 2026-03-17 | 2026-05-28 |
| Connectomic Guided DBS for Parkinson's Disease Cerebellothalamic optimized deep brain stimulation, Pallidothalamic optimized deep brain stimulation, No deep brain stimulation - Parkinson Disease, Tremor | Not applicable | Enrolling by invitation | Duke University | 20 | 2026-02-16 | 2026-09-03 |
| Detection of Internal Tremors by Oscillometry in Parkinson's Patient Detection of objective internal tremors - Parkinson Disease | Not applicable | Recruiting | University Hospital, Toulouse | 60 | 2026-02-10 | 2026-02-17 |
| Deep Brain Stimulation of the Deep Cerebellar Nuclei for Refractory Tremor Deep Brain Stimulation - Tremor, Essential Tremor | Phase 1 | Recruiting | The Cleveland Clinic | 12 | 2026-01-15 | 2026-07-10 |
| Virtual tES Device Treatment for Parkinson's Disease Motor Symptoms Transcranial Electrical Stimulation Device - PARKINSON DISEASE (Disorder) | Phase 1 / Phase 2 | Recruiting | U: The Mind Company | 30 | 2026-01-01 | 2026-01-27 |
| Effects of Transcutaneous Vagus Nerve Stimulation in Older Adults Active location tVNS, Sham Comparator - Older Adults Without Any Specific Clinical Condition, Autonomic Nervous System Imbalance | Not applicable | Completed | Universidade da Coruña | 12 | 2025-12-19 | 2026-03-02 |
| First-in-Human Study of ALN-SNCA in Adult Participants With Early Parkinson's Disease (PD) ALN-SNCA, Placebo - Parkinsons Disease | Phase 1 | Recruiting | Regeneron Pharmaceuticals | 46 | 2025-12-05 | 2026-09-21 |
| MRgFUS for Parkinson's Tremor MR-guided focused ultrasound thalamotomy - Parkinson s Disease, Tremor | Not applicable | Recruiting | Aarhus University Hospital | 20 | 2025-12-01 | 2026-01-07 |
| Gluten Challenge in Celiac Disease - Which Formulation of Gluten Gives the Best Response? Vital wheat gluten - Celiac Disease | Not applicable | Recruiting | Oslo University Hospital | 30 | 2025-08-01 | 2026-04-17 |
| Modulate Tremor Severity With Low-intensity Focused Ultrasound Stimulation Targeting the Deep Nucleus of Patients With Refractory Hand Tremor. Accelerated NaviFUS-ctbFUS stimulation - Parkinson Disease (PD), Essential Tremor | Not applicable | Recruiting | National Taiwan University Hospital | 12 | 2025-06-11 | 2025-09-15 |
| Cerebellar Transcranial Alternating Current Stimulation (tACS) to Modulate Parkinson's Disease Tremor Active-tACS, Sham-tACS, Unlocked-tACS - Parkinson's Disease (PD), Tremor | Not applicable | Recruiting | Universitätsklinikum Hamburg-Eppendorf | 10 | 2025-04-16 | 2026-09-01 |
| The Efficacy of Aldehyde Dehydrogenase Enzyme in Essential Tremor Patients: A Single-Center Study PICOZYME ET - Essential Tremor | Not applicable | Completed | Pico Entech Co., Ltd. | 31 | 2025-03-10 | 2026-09-29 |
| Effect of Kinesiotaping on Tremor in People With Parkinson's Disease Therapeutic Kinesiotaping, Sham Taping, Home Exercise Program - PARKINSON DISEASE (Disorder), Tremor | Not applicable | Completed | Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey | 45 | 2025-03-01 | 2026-04-29 |
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Parkinson Disease (74) · Essential Tremor (45) · Movement Disorders (20) · Dyskinesias (14) · Dystonia (14) · Hypokinesia (10) · Dysphonia (6) · Nervous System Diseases (6) · Multiple Sclerosis (5) · Muscle Rigidity (5) · Parkinsonian Disorders (5) · Anxiety Disorders (4) · Central Nervous System Diseases (4) · Dystonic Disorders (4)
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Deep Brain Stimulation (7) · Botulinum Toxins, Type A (4) · Tacrolimus (4) · Ethanol (3) · Radiosurgery (3) · incobotulinumtoxinA (3) · 1-Octanol (2) · Cannabidiol (2) · Propranolol (2) · Saline Solution (2) · octanoic acid (2) · Alprazolam (1) · Amantadine (1) · Bupivacaine (1) · Clonidine (1)
National Institute of Neurological Disorders and Stroke (NINDS) (10) · Great Lakes NeuroTechnologies Inc. (8) · University of Florida (4) · Abbott Medical Devices (3) · InSightec (3) · Jazz Pharmaceuticals (3) · Massachusetts Eye and Ear Infirmary (3) · Rambam Health Care Campus (3) · University of British Columbia (3) · Duke University (2) · Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta (2) · KU Leuven (2) · Maria Sklodowska-Curie National Research Institute of Oncology (2) · Medical University of Graz (2) · Oslo University Hospital (2)
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Dustin A Heldman, PhD (4) · Kristina Simonyan, MD, PhD (4) · Kenneth Follett (2) · Adityanjee Adityanjee, MD (1) · Agessandro Abrahao, MD, MSc (1) · Alan Glicklich, MD (1) · Aleksandra Napieralska (1) · Ali Veysel Ozden, M.D. (1) · Amy W Amara, MD, phD (1) · Andrew Evans, MD (1) · Anne Bernassau (1)
PMID 19126811, PMID 20519680, PMID 23667214, PMID 25185211, PMID 41626017, PMID 10665942, PMID 11391740, PMID 11812709, PMID 12768180, PMID 14718713, PMID 15210907, PMID 15233821, PMID 16216957, PMID 16381181, PMID 17052655, PMID 17845632, PMID 18433676, PMID 19218475, PMID 19454631, PMID 19940187, PMID 20175185, PMID 20201005, PMID 20830819, PMID 20937936, PMID 21384292, PMID 21594724, PMID 22454323, PMID 22722632, PMID 23408867, PMID 25929664, PMID 26621764, PMID 26927672, PMID 27101283, PMID 27622717, PMID 27720703, PMID 27808415, PMID 28789780, PMID 28991711, PMID 29193359, PMID 29204312, PMID 29742376, PMID 29777361, PMID 30382161, PMID 30945105, PMID 31111094, PMID 32815611, PMID 32873195, PMID 33096872, PMID 33510610, PMID 34454047
2016 (1), 2025 (1), 5UH3NS095553-04 (1), K23NS044997 (1), R01DC012545 (1), R01NS058487 (1), R01NS073683 (1), R03DC012429 (1), R37NS040894 (1), R43NS081902 (1), R44AG033947 (1), R44AG044293 (1), R44MD004049 (1), UH3TR003897 (1)