175 completed, 47 recruiting, 36 unknown, 17 terminated. 93 Not applicable, 42 Phase 2, 20 Phase 3, 19 Phase 4, 18 Phase 1.
Follow Dystonia: new trials by email Literature Review of Dystonia trials Research Report on Dystonia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Basket Clinical Study to Assess Glycerol Tributyrate in Patients With Mitochondrial Encephalopathy, Lactic Acidosis, Stroke-like Episodes (MELAS) or Leber's Hereditary Optic Neuropathy-Plus (LHON-Plus) Glycerol Tributyrate - MELAS Syndrome, Lebers Hereditory Optic Neuropathy With Extra Ocular Symptoms (LHON-Plus) | Phase 1 / Phase 2 | Not yet recruiting | George Washington University | 24 | 2027-03-01 | 2026-10-05 |
| Assessment of Cervical Range of Motion Restrictions in Infants With Arthrogenic Torticollis - A Feasibility Study Mobilisation of the upper cervical spine (but the effectiveness of the investigation is not part of the study evaluation) - Torticollis (Arthrogenic) | Not yet recruiting | Balgrist University Hospital | 10 | 2026-10-07 | 2026-10-08 | |
| DaxibotulinumtoxinA for Blepharospasm Botulinum Neurotoxin Type A - Blepharospasm of Both Eyelids, Blepharospasm of Left Eyelid | Phase 2 | Recruiting | University of Pennsylvania | 20 | 2026-09-24 | 2026-09-29 |
| Quantifying Motor Network Dynamics to Predict and Enhance Outcomes in Pediatric Dystonia DBS - Dystonia, Pediatric | Not applicable | Recruiting | Children's Hospital Medical Center, Cincinnati | 75 | 2026-09-01 | 2026-10-20 |
| Noninvasive Brain Stimulation for Cervical Dystonia Active continuous theta-burst stimulation, Sham continuous theta-burst stimulation - Cervical Dystonia | Not applicable | Recruiting | Fondazione Policlinico Universitario Campus Bio-Medico | 26 | 2026-07-06 | 2026-09-17 |
| Zinc as an Adjunctive Therapy for Cervical Dystonia Zinc citrate, Placebo - Cervical Dystonia | Phase 2 | Recruiting | University of Florida | 25 | 2026-06-01 | 2026-05-15 |
| Long-read Genome Sequencing for the Molecular Diagnosis of Dystonia Long-read whole genome sequencing - Dystonia, Movement Disorders | Not applicable | Recruiting | University Hospital, Strasbourg, France | 150 | 2026-04-22 | 2026-05-20 |
| Impact of rTMS on Abnormal Cortical fMRI in Patients With Dystonia Transcranial Magnetic Stimulation - Dystonia Disorder | Not applicable | Recruiting | Northwell Health | 10 | 2026-03-04 | 2026-10-16 |
| Validity and Reliability of the Hypertonia Assessment Tool (HAT) in Stroke Patients Stroke, Hypertonia | Not yet recruiting | Fatih Sultan Mehmet Training and Research Hospital | 60 | 2026-03-01 | 2026-02-24 | |
| A Study to Evaluate the Efficacy, Safety, and Tolerability of VIM0423 in Individuals With Isolated Dystonia VIM0423, VIM0423 Placebo - Dystonia | Phase 2 | Recruiting | Vima Therapeutics | 100 | 2026-02-05 | 2026-10-26 |
| LIFUS For Neurological Disorders LIFUS, Sham LIFUS - Parkinson's Disease (PD), Essential Tremor | Not applicable | Recruiting | University Health Network, Toronto | 50 | 2025-12-02 | 2026-08-13 |
| UltraSound-Guided Versus Non-Ultrasound-Guided Botulinum Toxin Injections in Cervical Dystonia [CUSTODY] Ultrasound-guided botulinum toxin injection, Non-ultrasound-guided botulinum toxin injection - Idiopathic Cervical Dystonia | Not applicable | Recruiting | Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta | 100 | 2025-11-01 | 2026-02-13 |
| Local Field Potentials in Dystonia Deep Brain Stimulation System - Dystonia, Dystonia, Focal | Recruiting | Newcastle-upon-Tyne Hospitals NHS Trust | 25 | 2025-09-04 | 2025-12-30 | |
| Predicting DBS Outcomes in Dystonia Using Wearable Gait Sensors Wearable Gait Sensor Analysis - Dystonia | Recruiting | Ruijin Hospital | 50 | 2025-08-01 | 2026-01-07 | |
| Intraoperative Microelectrode Recordings Using MAVEN Compared to Standard Recording Apparatuses Multifunctional Apparatus for Voltammetry, Electrophysiology, and Neuromodulation (MAVEN) - Essential Tremor, Parkinson's Disease | Recruiting | Mayo Clinic | 30 | 2025-07-29 | 2026-10-09 | |
| A Study of IPN10200 for the Treatment of Cervical Dystonia in Adults Corabotase, Placebo - Cervical Dystonia | Phase 2 | Recruiting | Ipsen | 132 | 2025-06-30 | 2026-09-08 |
| An Observational Study of Individuals With Isolated Dystonia Isolated/Primary Dystonia That Affects More Than One Region of the Body | Active not recruiting | Vima Therapeutics | 200 | 2025-06-17 | 2026-09-21 | |
| Using Technology for Prediction and Prevention of Infant Torticollis and Plagiocephaly in-app notification - Torticollis | Not applicable | Not yet recruiting | College of Staten Island, the City University of New York | 56 | 2025-06-01 | 2024-06-26 |
| The Effects of Waning of Botulinum Toxin in the Treatment of Cervical Dystonia Botulinum toxin type A injection - Cervical Dystonia, Primary | Phase 4 | Not yet recruiting | Western University, Canada | 45 | 2025-03-30 | 2025-03-20 |
| Development in Children Diagnosed With Congenital Muscular Torticollis Torticollis Congenital, Motor Development | Completed | Gazi University | 40 | 2025-03-13 | 2025-06-25 |
Showing 20 of 307. Sign in to see all of them.
Torticollis (119) · Parkinson Disease (61) · Dystonic Disorders (48) · Essential Tremor (37) · Movement Disorders (31) · Blepharospasm (20) · Cerebral Palsy (20) · Muscle Spasticity (16) · Tremor (14) · Dysphonia (12) · Dystonia, Focal, Task-Specific (9) · Ataxia (8) · Parkinsonian Disorders (8) · Chorea (7)
Pathological Conditions, Signs and Symptoms (307) · Signs and Symptoms (306) · Neurologic Manifestations (303) · Dyskinesias (300) · Nervous System Diseases (209) · Central Nervous System Diseases (139) · Brain Diseases (96) · Movement Disorders (91) · Basal Ganglia Diseases (70) · Neurodegenerative Diseases (66) · Synucleinopathies (61) · Parkinsonian Disorders (56) · Eye Diseases (24) · Mental Disorders (22)
Botulinum Toxins, Type A (37) · Deep Brain Stimulation (22) · abobotulinumtoxinA (14) · Transcranial Magnetic Stimulation (12) · Botulinum Toxins (10) · incobotulinumtoxinA (7) · Injections (4) · Blood Specimen Collection (3) · Magnetic Resonance Spectroscopy (3) · Saline Solution (3) · Trihexyphenidyl (3) · rimabotulinumtoxinB (3) · valbenazine (3) · Control Groups (2) · Exercise Test (2)
National Institute of Neurological Disorders and Stroke (NINDS) (35) · University of Florida (17) · Ipsen (11) · Allergan (9) · University Health Network, Toronto (7) · University of Minnesota (6) · Fondation Ophtalmologique Adolphe de Rothschild (5) · University of California, San Francisco (5) · University of Southern California (5) · Emory University (4) · Institut National de la Santé Et de la Recherche Médicale, France (4) · Mayo Clinic (4) · University of Texas Southwestern Medical Center (4) · Vanderbilt University Medical Center (4) · Western University, Canada (4)
United States (158) · France (37) · Germany (31) · Canada (26) · United Kingdom (20) · Italy (17) · Austria (13) · Poland (10) · Spain (10) · Australia (9) · China (9) · Turkey (Türkiye) (9) · Israel (7) · Russia (7) · Czechia (6)
Mark Hallett, M.D. (10) · Kristina Simonyan, MD, PhD (5) · Aparna Wagle Shukla, MD (3) · Mandar Jog, MD (3) · Akira Endo (2) · Aparna Wagle Shukla, M.D. (2) · David Vaillancourt, PhD (2) · Debra J Ehrlich, M.D. (2) · Emmanuel Flamand-Roze, MD, PhD (2) · H. A. Jinnah, MD, PhD (2) · Joseph Jankovic (2) · Kendall Lee, MD, PhD (2)
PMID 19191832, PMID 20359934, PMID 25324317, PMID 26679193, PMID 27939583, PMID 28674168, PMID 34316644, PMID 12566335, PMID 15689584, PMID 16206144, PMID 17093249, PMID 17905796, PMID 18439222, PMID 20801261, PMID 20841416, PMID 21312284, PMID 21386109, PMID 21553081, PMID 21764407, PMID 22021883, PMID 22054223, PMID 22398268, PMID 22550086, PMID 22924536, PMID 23123071, PMID 23604344, PMID 23687362, PMID 23779062, PMID 23801734, PMID 23861342, PMID 24396131, PMID 24436111, PMID 24440061, PMID 24828895, PMID 24951081, PMID 25084088, PMID 25127231, PMID 25168295, PMID 25175271, PMID 25476727, PMID 25524875, PMID 25595221, PMID 25673742, PMID 25823758, PMID 25923718, PMID 25929664, PMID 26046412, PMID 26074391, PMID 26204475, PMID 26495947
U54NS065701 (3), 2005 (2), U54TR001456 (2), 2004 (1), 2015 (1), 2016 (1), K23NS149280 (1), KL2TR000065 (1), R01DC011805 (1), R01DC012545 (1), R01DC016315 (1), R01DE030464 (1), R01EB006136 (1), R01HD112563 (1), R01NS058487 (1)