5 completed, 3 recruiting, 1 not yet recruiting, 1 unknown. 10 Phase 1, 4 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 10 | Completed 5, Recruiting 3, Not yet recruiting 1, Unknown 1 |
| Phase 2 | 4 | Completed 2, Not yet recruiting 1, Recruiting 1 |
Follow Tremor: new trials by email Literature Review of Tremor trials Research Report on Tremor
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Basket Clinical Study to Assess Glycerol Tributyrate in Patients With Mitochondrial Encephalopathy, Lactic Acidosis, Stroke-like Episodes (MELAS) or Leber's Hereditary Optic Neuropathy-Plus (LHON-Plus) Glycerol Tributyrate - MELAS Syndrome, Lebers Hereditory Optic Neuropathy With Extra Ocular Symptoms (LHON-Plus) | Phase 1 / Phase 2 | Not yet recruiting | George Washington University | 24 | 2027-03-01 | 2026-10-05 |
| Deep Brain Stimulation of the Deep Cerebellar Nuclei for Refractory Tremor Deep Brain Stimulation - Tremor, Essential Tremor | Phase 1 | Recruiting | The Cleveland Clinic | 12 | 2026-01-15 | 2026-07-10 |
| Virtual tES Device Treatment for Parkinson's Disease Motor Symptoms Transcranial Electrical Stimulation Device - PARKINSON DISEASE (Disorder) | Phase 1 / Phase 2 | Recruiting | U: The Mind Company | 30 | 2026-01-01 | 2026-01-27 |
| First-in-Human Study of ALN-SNCA in Adult Participants With Early Parkinson's Disease (PD) ALN-SNCA, Placebo - Parkinsons Disease | Phase 1 | Recruiting | Regeneron Pharmaceuticals | 46 | 2025-12-05 | 2026-09-21 |
| The Study of Rest Tremor Suppression by Using Electrical Muscle Stimulation electrical muscle stimulation - Rest Tremor, Parkinson's Disease | Phase 1 | Unknown | Chulalongkorn University | 60 | 2015-02-01 | 2015-02-24 |
| Effects of Octanoic Acid for Treatment of Essential Voice Tremor Octanoic acid, Inactive capsule - Essential Voice Tremor, Vocal Tremor | Phase 1 / Phase 2 | Completed | Syracuse University | 17 | 2013-07-01 | 2018-08-20 |
| Octanoic Acid for Essential Tremor Octanoic Acid - Essential Tremor | Phase 1 | Completed | National Institute of Neurological Disorders and Stroke (NINDS) | 18 | 2011-10-28 | 2019-12-16 |
| Efficacy of Levetiracetam in Essential Tremor levetiracetam, placebo - Essential Tremor | Phase 1 / Phase 2 | Completed | Southern California Institute for Research and Education | 10 | 2005-01-01 | 2009-04-17 |
| 1-Octanol to Treat Essential Tremor 1-Octanol - Essential Tremor | Phase 1 | Completed | National Institute of Neurological Disorders and Stroke (NINDS) | 42 | 2001-05-01 | 2008-03-04 |
| 1-Octanol to Treat Essential Tremor 1-Octanol - Essential Tremor | Phase 1 | Completed | National Institute of Neurological Disorders and Stroke (NINDS) | 12 | 2000-01-01 | 2008-03-04 |
Essential Tremor (6) · Parkinson Disease (3) · Muscle Rigidity (2) · Acidosis, Lactic (1) · Anxiety Disorders (1) · Cognition Disorders (1) · Cognitive Dysfunction (1) · Dyskinesias (1) · Dysphonia (1) · Dystonia (1) · Hearing Loss (1) · Hypokinesia (1) · MELAS Syndrome (1) · Migraine Disorders (1)
Central Nervous System Diseases (10) · Nervous System Diseases (10) · Neurologic Manifestations (10) · Pathological Conditions, Signs and Symptoms (10) · Signs and Symptoms (10) · Dyskinesias (9) · Movement Disorders (8) · Brain Diseases (4) · Basal Ganglia Diseases (3) · Musculoskeletal Diseases (3) · Neurodegenerative Diseases (3) · Parkinsonian Disorders (3) · Synucleinopathies (3) · Mental Disorders (2) · Muscle Hypertonia (2)
1-Octanol (2) · octanoic acid (2) · Deep Brain Stimulation (1) · Levetiracetam (1)
National Institute of Neurological Disorders and Stroke (NINDS) (3) · Chulalongkorn University (1) · George Washington University (1) · Regeneron Pharmaceuticals (1) · Southern California Institute for Research and Education (1) · Syracuse University (1) · The Cleveland Clinic (1) · U: The Mind Company (1)
United States (8) · Canada (1) · Netherlands (1)
Anne Chiaramello, Ph.D. (1) · Debra Regier, M.D., Ph.D. (1) · Mark Hallett, M.D. (1) · Roongroj Bhidayasiri, MD, FRCP (1) · Soren Y Lowell, PhD (1) · Steven S Schreiber, MD (1) · Wei-Liang Chen, M.D. (1)
PMID 14718713, PMID 15210907, PMID 21594724, PMID 22454323, PMID 23408867, PMID 26927672
2025 (1), R03DC012429 (1), UH3TR003897 (1)