15 completed, 7 unknown, 5 recruiting, 2 not yet recruiting. 16 Not applicable, 3 Phase 1, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 16 | Completed 10, Unknown 4, Recruiting 2 |
| Phase 1 | 3 | Recruiting 2, Completed 1 |
| Phase 2 | 2 | Completed 1, Recruiting 1 |
Follow Muscle Rigidity: new trials by email Literature Review of Muscle Rigidity trials Research Report on Muscle Rigidity
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Spinal Mobility, Rigidity, and Kinesiophobia in PD and TMD PARKINSON DISEASE (Disorder), Rigidity | Recruiting | Mustafa Kemal University | 60 | 2026-09-23 | 2026-10-05 | |
| Validity and Reliability of the Hypertonia Assessment Tool (HAT) in Stroke Patients Stroke, Hypertonia | Not yet recruiting | Fatih Sultan Mehmet Training and Research Hospital | 60 | 2026-03-01 | 2026-02-24 | |
| Virtual tES Device Treatment for Parkinson's Disease Motor Symptoms Transcranial Electrical Stimulation Device - PARKINSON DISEASE (Disorder) | Phase 1 / Phase 2 | Recruiting | U: The Mind Company | 30 | 2026-01-01 | 2026-01-27 |
| First-in-Human Study of ALN-SNCA in Adult Participants With Early Parkinson's Disease (PD) ALN-SNCA, Placebo - Parkinsons Disease | Phase 1 | Recruiting | Regeneron Pharmaceuticals | 46 | 2025-12-05 | 2026-09-21 |
| Blood Flow Technique Effect on the Muscle Mechanics Biceps, Muscle Rigidity | Not yet recruiting | Okan University | 57 | 2025-03-03 | 2025-03-06 | |
| Differential Assessment of Hypertonia Continuous passive motion device (CPM) of ankle - fast, Continuous passive motion device (CPM) of ankle - slow - SCI - Spinal Cord Injury, PD - Parkinson's Disease | Not applicable | Recruiting | Chang Gung University | 45 | 2024-10-09 | 2024-10-15 |
| Acupuncture and Moxibustion for Motor Symptoms in Early Parkinson's Disease Acupuncture and Moxibustion (AM), Sham Acupuncture and Moxibustion (Sham-AM) - Parkinson's Disease (PD) | Not applicable | Recruiting | Jiani Wu | 60 | 2024-08-01 | 2025-07-20 |
| Comparison of Different Feeding Appliances for Cleft Palate Babies flexible feeding plate - Cleft Palate | Not applicable | Completed | Tanta University | 30 | 2023-07-01 | 2023-10-26 |
| Effects of Whole Body Vibration in Parkinson's Disease Symptoms Whole body Vibration, Habitual Therapy, Placebo whole body vibration - Parkinson Disease | Not applicable | Unknown | University of Seville | 46 | 2023-01-01 | 2022-11-17 |
| Surface EMG to Measure Paratonia in Dementia Elbow movement - Dementia Alzheimers | Unknown | University Medical Center Groningen | 280 | 2022-11-01 | 2022-11-04 | |
| Neurophysiological Evaluation of Muscle Tone Robot-assisted examination - Muscle Tone Abnormalities, Rigidity, Muscle | Unknown | Neuromed IRCCS | 60 | 2021-10-01 | 2023-03-22 | |
| Investigation on a Topical Cosmetic Pain Lotion (Egyfil) for Stiffness and Pain Relief Egyfil Pain Lotion - Pain, Muscle Rigidity | Not applicable | Completed | Contrad Swiss SA | 26 | 2021-06-12 | 2023-07-20 |
| Physiotherapeutic Case Studies in Frozen Shoulder Pathology First data analysis, Second data analysis, database - Articular; Rigid | Not applicable | Completed | GEMA LEÓN BRAVO | 30 | 2021-02-03 | 2022-01-13 |
| Effects of a Dynamic Upper Limb Orthosis in Patients With Parkinson's Disease Dynamic Upper Limb Orthosis - Parkinson Disease, Tremor, Limb | Not applicable | Unknown | Universidad de Burgos | 40 | 2021-01-01 | 2022-06-27 |
| Clinical Evaluation of Acuity 200 (Fluoroxyfocon A) RGP Contact Lens Acuity 200 (Fluoroxyfocon A) contact lens, Acuity 100 (Hexafocon A) contact lens - Refractive Errors | Not applicable | Completed | Acuity Polymers, Inc. | 74 | 2019-04-01 | 2020-05-12 |
| Joint Preserving Surgery for Correction of Spasmodic Flat- Foot in Skeletally Mature Foot Joint Preserving Surgery in spasmodic flat foot - Flat Foot; Rigid, Flat Foot; Spastic | Not applicable | Unknown | Assiut University | 22 | 2019-04-01 | 2019-03-19 |
| Modified Exercise Programme in Individuals With Parkinson's Disease Modified exercise programme, Medication - Parkinson Disease | Not applicable | Completed | Mahidol University | 22 | 2018-03-01 | 2018-11-15 |
| Differents Intensities of Passive Stretching on ROM, Neuromuscular and Performance in Soccer Players: A Blinded RCT Passive static stretch - Contracture of Muscle, Thigh, Muscle Rigidity | Not applicable | Unknown | Universidade Federal do Rio Grande do Norte | 40 | 2017-05-09 | 2017-05-12 |
| Short-term Effect of Positioning Cushions and Harmonic Techniques on Paratonia in Persons With Dementia Supporting cushions, Harmonic techniques - Dementia, Paratonia | Not applicable | Completed | University Ghent | 22 | 2016-04-24 | 2023-05-10 |
| the Diagnostic Value of Rigiscan Test (Nocturnal Penile Tumescence and Rigidity, NPTR) in Chinese Males Rigiscan test - Erectile Dysfunction | Unknown | The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School | 1000 | 2015-09-01 | 2015-10-14 |
Showing 20 of 31. Sign in to see all of them.
Parkinson Disease (12) · Muscle Spasticity (7) · Tremor (5) · Hypokinesia (4) · Dementia (3) · Dystonia (3) · Cerebral Palsy (2) · Muscle Hypertonia (2) · Alzheimer Disease (1) · Caregiver Burden (1) · Cleft Palate (1) · Cognitive Dysfunction (1) · Contracture (1) · Dyskinesias (1)
Muscular Diseases (31) · Musculoskeletal Diseases (31) · Nervous System Diseases (31) · Neurologic Manifestations (31) · Neuromuscular Manifestations (31) · Pathological Conditions, Signs and Symptoms (31) · Signs and Symptoms (31) · Muscle Hypertonia (29) · Central Nervous System Diseases (20) · Brain Diseases (19) · Neurodegenerative Diseases (14) · Basal Ganglia Diseases (12) · Parkinsonian Disorders (12) · Synucleinopathies (12) · Movement Disorders (11)
Acupuncture Therapy (1) · Botulinum Toxins (1) · Contact Lenses (1) · Database Management Systems (1) · Dosage Forms (1) · Immunoglobulins, Intravenous (1) · Moxibustion (1) · Sodium Chloride (1) · carboxypeptidase M (1) · incobotulinumtoxinA (1)
National Institute of Neurological Disorders and Stroke (NINDS) (4) · University Ghent (2) · Acuity Polymers, Inc. (1) · Assistive Technology Clinic, Canada (1) · Assiut University (1) · Boston University Charles River Campus (1) · Chang Gung University (1) · Codman & Shurtleff (1) · Contrad Swiss SA (1) · Fatih Sultan Mehmet Training and Research Hospital (1) · GEMA LEÓN BRAVO (1) · Jiani Wu (1) · Mahidol University (1) · Medical University of Vienna (1) · Mustafa Kemal University (1)
United States (10) · Spain (3) · Belgium (2) · Canada (2) · China (2) · Italy (2) · Turkey (Türkiye) (2) · Austria (1) · Brazil (1) · Egypt (1) · Netherlands (1) · Taiwan (1) · Thailand (1)
Codrin I Lungu, M.D. (1) · Fuengfa Khobkhun (1) · Galit Kleiner-Fisman, MD (1) · Hubert Fernandez, MD (1) · Jaime Rando Anaya, Physiotherap (1) · James A Bonafini, BS,MS (1) · Jonathan T Megerian, MD (1) · Kelly Foote, MD (1) · Leopold Schmetterer, Prof. Dr. (1) · Michael Okun, MD (1) · Ramon Rodriguez, MD (1)
PMID 25536218, PMID 26655100, PMID 36602886, PMID 37784053, PMID 38588457
2025 (1), K23NS044997 (1)