52 completed, 16 recruiting, 15 unknown, 10 terminated. 22 Not applicable, 15 Phase 2, 10 Phase 1, 3 Phase 3, 3 Phase 4.
Follow Dystonic Disorders: new trials by email Literature Review of Dystonic Disorders trials Research Report on Dystonic Disorders
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| VTS Sensorimotor Neuromodulation in WC Vibro-tactile stimulation - Writer's Cramp, Dystonias | Not applicable | Not yet recruiting | Ottawa Hospital Research Institute | 10 | 2026-12-01 | 2026-10-26 |
| Impact of rTMS on Abnormal Cortical fMRI in Patients With Dystonia Transcranial Magnetic Stimulation - Dystonia Disorder | Not applicable | Recruiting | Northwell Health | 10 | 2026-03-04 | 2026-10-16 |
| A Study to Evaluate the Efficacy, Safety, and Tolerability of VIM0423 in Individuals With Isolated Dystonia VIM0423, VIM0423 Placebo - Dystonia | Phase 2 | Recruiting | Vima Therapeutics | 100 | 2026-02-05 | 2026-10-26 |
| Attention and Eye Movement in Parkinson's Disease Normal therapeutic DBS, Reduced current DBS, Reduced frequency DBS - Essential Tremor, Parkinson's Disease (PD) | Not applicable | Recruiting | University of Nebraska | 138 | 2025-09-22 | 2026-05-05 |
| Local Field Potentials in Dystonia Deep Brain Stimulation System - Dystonia, Dystonia, Focal | Recruiting | Newcastle-upon-Tyne Hospitals NHS Trust | 25 | 2025-09-04 | 2025-12-30 | |
| An Observational Study of Individuals With Isolated Dystonia Isolated/Primary Dystonia That Affects More Than One Region of the Body | Active not recruiting | Vima Therapeutics | 200 | 2025-06-17 | 2026-09-21 | |
| Registry and Natural History of Epilepsy-Dyskinesia Syndromes Epilepsy-Dyskinesia, Epilepsy | Recruiting | Boston Children's Hospital | 700 | 2025-06-01 | 2025-08-17 | |
| Bilateral Single-Electrode VO Combined With STN-DBS for Treating Meige Syndrome deep brain stimulation - Meige Syndrome | Not applicable | Recruiting | Huashan Hospital | 20 | 2025-03-06 | 2025-04-04 |
| Focused Ultrasound Unilateral Pallidotomy for Medication-Refractory Limb Dystonia Exablate MR-guided Focused Ultrasound Pallidotomy, Sham Sham Exablate MRgFUS Pallidotomy - Limb Dystonia, Idiopathic Dystonia | Not applicable | Recruiting | Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta | 34 | 2025-01-27 | 2026-02-11 |
| Pharmacogenomic Contributions to Trihexyphenidyl Biotransformation and Response in Children With Dystonic Cerebral Palsy Trihexyphenidyl - Pediatric Disorder, Genetic Predisposition | Phase 1 | Recruiting | Children's Mercy Hospital Kansas City | 40 | 2024-10-15 | 2026-06-24 |
| A Retrospective Survey-based Multicenter Study to Delineate the Molecular and Phenotypic Spectrum of Epilepsy-dyskinesia Syndromes Epilepsy in Children, Dyskinesias | Recruiting | Boston Children's Hospital | 500 | 2024-07-01 | 2026-03-18 | |
| Focused Ultrasound Pallidotomy for Dyskinetic Cerebral Palsy in Pediatric and Young Adult Subjects Focused Ultrasound Pallidotomy - Cerebral Palsy, Dyskinetic, Secondary Dystonia | Not applicable | Recruiting | Children's National Research Institute | 10 | 2024-01-26 | 2026-06-11 |
| A Comparison Between STN-DBS and GPi-DBS in Meige Syndrome Evaluated by Flexible Electrodes Bilateral STN deep brain stimulation, Bilateral GPi deep brain stimulation - Meige Syndrome | Not applicable | Unknown | Qilu Hospital of Shandong University | 100 | 2023-11-30 | 2024-03-05 |
| Assessment of Long-term Clinical Response to BoNT in Cervical Dystonia CC BoNT/A, CF BoNT/A, CF to CC BoNT/A - Cervical Dystonia | Completed | Merz Therapeutics GmbH | 270 | 2023-07-08 | 2024-08-21 | |
| İnvestigating Dysphagia in Pediatric Dystonia Dystonia Disorder | Active not recruiting | Gazi University | 25 | 2023-03-17 | 2025-02-11 | |
| Enhancing Sensorimotor Processing in Children With Dystonia No intervention - Dystonia, Dystonic Cerebral Palsy | Not yet recruiting | King's College London | 90 | 2023-02-01 | 2022-11-10 | |
| Sensorimotor Integration in Monogenic Parkinson-dystonia Syndromes Transcranial magnetic stimulation (TMS), Video-based clinical examination, 24 hours drug withdrawal of dopaminergic medication - Parkinson, Dystonia | Unknown | University Hospital Schleswig-Holstein | 120 | 2023-01-01 | 2023-06-23 | |
| Neurosurgical Outcome Network Aneurysms, Arteriovenous Malformations | Recruiting | Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta | 4500 | 2022-12-05 | 2026-03-30 | |
| Effects of Neuromodulation in Laryngeal Dystonia repetitive transcranial magnetic stimulation (rTMS), sham rTMS - Laryngeal Dystonia, Focal Dystonia | Not applicable | Recruiting | MGH Institute of Health Professions | 25 | 2021-06-10 | 2026-02-20 |
| Heart Rate Variability Biofeedback Training in Psychogenic Disorders Heart rate variability biofeedback training (Symbiocenter), psychoeducation session - Psychogenic Dystonia | Not applicable | Unknown | University Hospital, Montpellier | 40 | 2021-04-30 | 2024-05-28 |
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Dystonia (44) · Dystonia, Focal, Task-Specific (17) · Movement Disorders (14) · Torticollis (12) · Blepharospasm (8) · Parkinson Disease (7) · Essential Tremor (6) · Dysphonia (5) · Meige Syndrome (5) · Cerebral Palsy (4) · Nervous System Diseases (4) · Tremor (4) · Ataxia (3) · Chorea (3)
Central Nervous System Diseases (97) · Nervous System Diseases (94) · Movement Disorders (84) · Pathological Conditions, Signs and Symptoms (58) · Neurologic Manifestations (57) · Signs and Symptoms (57) · Dyskinesias (51) · Brain Diseases (24) · Basal Ganglia Diseases (14) · Eye Diseases (8) · Eyelid Diseases (8) · Neurodegenerative Diseases (8) · Otorhinolaryngologic Diseases (8) · Neuromuscular Manifestations (7) · Parkinsonian Disorders (7)
Transcranial Magnetic Stimulation (8) · Botulinum Toxins, Type A (5) · Deep Brain Stimulation (5) · Trihexyphenidyl (3) · Blood Specimen Collection (2) · Amitriptyline (1) · Amlodipine (1) · Baclofen (1) · Botulinum Toxins (1) · Clonazepam (1) · Constraint Induced Movement Therapy (1) · Diazepam (1) · Electric Stimulation (1) · Electromyography (1) · Fructose (1)
National Institute of Neurological Disorders and Stroke (NINDS) (33) · Fondation Ophtalmologique Adolphe de Rothschild (4) · Boston Children's Hospital (2) · Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta (2) · Institut National de la Santé Et de la Recherche Médicale, France (2) · University Hospital Schleswig-Holstein (2) · University Hospital, Lille (2) · University of Minnesota (2) · University of Texas Southwestern Medical Center (2) · Vima Therapeutics (2) · Abbott Medical Devices (1) · Acıbadem Atunizade Hospital (1) · Ain Shams University (1) · Assistance Publique - Hôpitaux de Paris (1) · Carlos Pena, PhD, MS (1)
United States (56) · France (12) · China (6) · Canada (4) · Germany (4) · Italy (4) · Turkey (Türkiye) (2) · United Kingdom (2) · Australia (1) · Finland (1) · Hungary (1) · Serbia (1) · Slovenia (1) · South Korea (1) · Spain (1)
Mark Hallett, M.D. (11) · Teresa J Kimberley, PhD, PT (2) · Aimee J Nelson, PhD (1) · Alexandre Kreisler, MD (1) · Anne Weissbach, MD (1) · Bhatia P Kailash, MD, DM, FRCP (1) · Carlos L Pena, PhD (1) · Charles Adler, MD, PhD (1) · Chima Oluigbo, MD (1) · Chris Honey, MD,DPhil,FRCSC (1) · Christopher K Kovach, PhD (1) · Codrin I Lungu, M.D. (1) · David Simpson, MD (1)
PMID 21442656, PMID 23340117, PMID 26217209, PMID 26239770, PMID 26360238, PMID 26679193, PMID 27575646, PMID 27911747, PMID 27939583, PMID 28543038, PMID 28674168, PMID 28827008, PMID 29076564, PMID 29219190, PMID 30264427, PMID 30473192, PMID 30582159, PMID 30755797, PMID 30840778, PMID 31359200, PMID 31571302, PMID 31930574, PMID 32098856, PMID 32311207, PMID 32505028, PMID 32655462, PMID 32669012, PMID 32811896, PMID 32960985, PMID 33004625, PMID 33504639, PMID 33858994, PMID 34513166, PMID 34875561, PMID 34887826, PMID 35584784, PMID 36440757, PMID 36640203, PMID 37148555, PMID 37338705, PMID 37397896, PMID 38411747, PMID 39287592, PMID 40910449, PMID 41535352, PMID 42097654, PMID 42753227
2016 (1), K24DC018603 (1), M01RR000400 (1), P20GM130447 (1), R01DE030464 (1)