63 completed, 19 unknown, 14 terminated, 10 withdrawn. 37 Phase 2, 30 Not applicable, 27 Phase 3, 14 Phase 1, 11 Phase 4.
Follow Glutamine: new trials by email Literature Review of Glutamine trials Research Report on Glutamine
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Trial of First-line Gemcitabine and Nab-paclitaxel With or Without L-glutamine in Advanced Pancreatic Cancer Gemcitabine (1000 mg/m2), Nab-paclitaxel, L-glutamine - Pancreatic Cancer | Phase 2 | Not yet recruiting | Jun Gong, MD | 200 | 2026-12-01 | 2026-10-08 |
| Glutamine for the Prophylaxis of Vincristine-induced Neuropathy in Children and Adolescents With Cancer. Glutamine (Pharmacological doses) - Neuropathy, Cancer | Phase 3 | Not yet recruiting | Ain Shams University | 70 | 2025-12-30 | 2025-12-17 |
| A Randomized Controlled Trial of Five - Flavor Sophora Flavescens Enteric - Coated Capsules for Radiation - Induced Proctitis After Pelvic Radiotherapy five - flavor sophora flavescens enteric - coated capsules plus glutamine and warm - water sitz baths, glutamine and warm - water sitz baths - Radiation - Induced Proctitis | Phase 2 | Not yet recruiting | Peking University First Hospital | 124 | 2025-06-30 | 2025-07-08 |
| Efficacy and Safety of Thalidomide Combined With Glutamine in the Treatment of Radiation Intestinal Injury. Thalidomide, Glutamine, Thalidomide+Glutamine - Radiation Enteritis | Phase 2 | Recruiting | Yongquan Shi | 150 | 2024-09-30 | 2026-03-27 |
| Mechanisms of Gulf War Illness Oral Glutamine, Control Arm - Gulf War Illness, Irritable Bowel Syndrome | Not applicable | Recruiting | VA Office of Research and Development | 80 | 2023-10-16 | 2026-08-19 |
| Glutamine Combined With Thalidomide in Preventing Radiation-induced Oral Mucositis glutamine combined with thalidomide, glutamine alone - Mucositis Oral | Phase 3 | Completed | Air Force Military Medical University, China | 138 | 2023-09-15 | 2026-07-01 |
| Effect of L-Glutamine on Pulmonary Artery Pressure in Patients With Non-Transfusion-Dependent Thalassemia L-glutamine - Pulmonary Artery Pressure, Thalassemia | Phase 2 / Phase 3 | Completed | Mazandaran University of Medical Sciences | 8 | 2023-08-15 | 2025-10-07 |
| Oral Supplementation of Glutamine on Gastric Cancer Patients After Gastrectomy oral glutamine, Maltodextrin - Gastric Cancer, Immunonutrition | Not applicable | Recruiting | National Taiwan University Hospital | 120 | 2023-02-21 | 2025-12-23 |
| A Study of Glutamine to Treat Intestinal Permeability in Functional Dyspepsia Glutamine, Placebo - Functional Dyspepsia | Phase 1 / Phase 2 | Completed | David J. Cangemi | 12 | 2023-02-16 | 2026-02-03 |
| Glutamine and Traumatic Brain Injury Glutamine, Placcebo - Brain Injuries, Traumatic | Early Phase 1 | Unknown | Assiut University | 60 | 2022-10-30 | 2022-10-06 |
| Glutamine Plus L. Reuteri Prevents TKI Therapy-diarrhea in Patients With NSCLC Glutamine plus L. reuteri - Non-Small Cell Lung Cancer With EGFR Mutation | Phase 3 | Recruiting | Instituto Nacional de Cancerologia de Mexico | 28 | 2022-03-01 | 2026-04-09 |
| Glutamine Role in Preventing Vaso-occlusive Crisis Among SCD Patients L-Glutamine, Oral Powder for Reconstitution, Standard of care - Sickle Cell Disease | Phase 4 | Completed | Ain Shams University | 60 | 2022-01-04 | 2024-01-09 |
| Efficacy of Glutamine in Management of Radiation Mucositis Glutamine - Radiation-Induced Mucositis | Not applicable | Unknown | Ain Shams University | 40 | 2022-01-01 | 2023-05-12 |
| Effect of Supplementation With HMB and Glutamine in Wound Healing on Bloody Areas glutamine supplementation, HMB, Placebo - Wound Healing, Diabetic | Phase 4 | Unknown | Hospital General de Mexico | 30 | 2021-06-01 | 2020-09-03 |
| Alanyl-glutamine Supplementation for C. Difficile Treatment (ACT) Alanyl-glutamine - Clostridioides Difficile Infection, Clostridium Difficile Infection | Phase 2 | Recruiting | University of Virginia | 260 | 2021-06-01 | 2024-10-26 |
| Glutamine Supplementation and Short-term Mortality in Covid-19 Standard enteral nutrition, Glutamine - Covid19 | Phase 3 | Completed | Assiut University | 60 | 2021-05-30 | 2021-11-05 |
| Trial of First-line L-glutamine With Gemcitabine and Nab-paclitaxel in Advanced Pancreatic Cancer Gemcitabine, Nab-paclitaxel, L-glutamine - Advanced Pancreatic Adenocarcinoma, Pancreatic Cancer | Phase 1 | Completed | Jun Gong, MD | 18 | 2021-05-13 | 2025-08-06 |
| Pharmacokinetics and Safety of Endari (L-glutamine) in Sickle Cell Disease Patients L-glutamine - Sickle Cell Disease, Pharmacokinetics | Phase 4 | Completed | Emmaus Medical, Inc. | 13 | 2021-01-04 | 2022-08-02 |
| Glutamine Supplementation in People With Immune Dysregulation L-glutamine - Eczema, MTOROC1 Signaling | Early Phase 1 | Withdrawn | National Institute of Allergy and Infectious Diseases (NIAID) | 2020-03-12 | 2020-03-16 | |
| Effect of Parenteral Glutamine on Myocardial Injury and Inflammation Biomarkers L-alanyl-L-glutamine dipeptide, Placebo - Insufficiency;Cardiac | Not applicable | Completed | Instituto Mexicano del Seguro Social | 56 | 2020-02-04 | 2023-10-04 |
Showing 20 of 114. Sign in to see all of them.
Anemia, Sickle Cell (7) · Sepsis (7) · Critical Illness (6) · Hyperphagia (5) · Lymphoma (5) · Peripheral Nervous System Diseases (5) · Breast Neoplasms (4) · Head and Neck Neoplasms (4) · Multiple Organ Failure (4) · Stomatitis (4) · Thalassemia (4) · Burns (3) · Colorectal Neoplasms (3) · Lymphoma, Large B-Cell, Diffuse (3) · Mucositis (3)
M.D. Anderson Cancer Center (6) · Ain Shams University (4) · Emmaus Medical, Inc. (4) · AHS Cancer Control Alberta (2) · Assiut University (2) · Changi General Hospital (2) · Columbia University (2) · Daren K. Heyland (2) · Hospital Universitari Son Dureta (2) · Jun Gong, MD (2) · Massachusetts General Hospital (2) · National Center for Research Resources (NCRR) (2) · National Institute of Allergy and Infectious Diseases (NIAID) (2) · Shahid Beheshti University (2) · University Hospital, Rouen (2)
United States (49) · Canada (7) · China (7) · Egypt (5) · Mexico (5) · Spain (5) · France (4) · Iran (4) · Taiwan (4) · Brazil (3) · Singapore (3) · United Kingdom (3) · Belgium (2) · Germany (2) · India (2)
Yago Nieto, MD, PHD (4) · Yutaka Niihara, MD (3) · Daren Heyland, MD (2) · Jun Gong, MD (2) · Michael Sawyer, MD (2) · Ronald G Tompkins, MD, ScD (2) · Zahra Vahdat Shariatpanahi, MD, PhD (2) · Abbot R. Laptook, MD (1) · Ademar Avelar, PhD (1) · Agneta L. Sunehag (1) · Albert Lie, Dr (1) · Alfonso Vidal Casariego, MD (1) · Alvin Wong (1) · Anne Mercier, MD (1) · Augusta Saulys, MD (1)
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I01CX001477 (1), M01RR000070 (1), M01RR000750 (1), M01RR000997 (1), M01RR001032 (1), M01RR002558 (1), M01RR006022 (1), M01RR008084 (1), P50AT000076 (1), P50GM021700 (1), R21DK077415 (1), R21DK088027 (1), U01HD036790 (1), U10CA037429 (1), U10HD021364 (1)