216 completed, 59 unknown, 19 terminated, 15 recruiting. 159 Not applicable, 74 Phase 2, 69 Phase 3, 32 Phase 4, 21 Phase 1.
Follow Docosahexaenoic Acids: new trials by email Literature Review of Docosahexaenoic Acids trials Research Report on Docosahexaenoic Acids
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effect of Fish Oil Supplementation on the Voice of Female Professional Voice Users (PVU) Omega-3 Polyunsaturated Fatty Acids - Mitigation of Acute Voice Changes Follwing Rigorous Voice Use | Not applicable | Not yet recruiting | Baylor University | 68 | 2026-10-01 | 2026-09-02 |
| Supplementation Absorption Comparison Aquacelle® Omega 3, Comparator Omega 3, Plexosome® Vitamin D3 - Healthy Volunteer | Phase 4 | Recruiting | RDC Clinical Pty Ltd | 160 | 2026-08-31 | 2026-09-10 |
| Effects of Adjunct Omega-3 Long Chain Polyunsaturated Fatty Acids in Pulmonary Tuberculosis Patient: an Early Bactericidal Activity and Inflammatory Trial Omega-3 (EPA+DHA), Placebo - Tuberculosis, Inflammation Biomarkers | Phase 2 | Recruiting | North-West University, South Africa | 40 | 2026-08-19 | 2026-09-09 |
| Impact of an Optimized Omega-3 Formulation on Inflammation and Endothelial Dysfunction in Pulmonary Arterial Hypertension OMega 3 - PAH | Not applicable | Not yet recruiting | University Hospital, Strasbourg, France | 22 | 2026-07-01 | 2026-07-13 |
| Dietary Supplements and Middle Aged Women (Collagen & Omega) Collagen peptides and omega-3, Placebo control - Cognition, Inflammation Biomarkers | Not applicable | Recruiting | Loughborough University | 34 | 2026-05-01 | 2026-08-03 |
| Impact of an Omega-3 Enriched Oral Nutritional Supplement on Improving Surgical Outcomes in Patients With Peritoneal Carcinomatosis Undergoing Cytoreductive Surgery ONS enriched with Omega-3, Standard ONS - Peritoneal Carcinosis, Peritoneal Metastases | Not applicable | Not yet recruiting | Catholic University of the Sacred Heart | 28 | 2026-04-01 | 2026-03-17 |
| Long-Term Omega-3 and Omega-3 Index >8%: Effects on Physiological Recovery Oil Supplementation - Focus on Omega 3 Index on Recovery | Not applicable | Not yet recruiting | St. Mary's University, Twickenham | 46 | 2026-02-28 | 2026-02-27 |
| Effects of DHA in Patients With Multiple Sclerosis Docosahexaenoic Acid (DHA) Dietary Supplement, Sunflower Oil - Multiple Sclerosis, Performance Enhancement | Not applicable | Enrolling by invitation | Francisco Javier Martínez Noguera | 100 | 2026-01-01 | 2026-01-16 |
| Immunonutrition for Surgical Prehabilitation of Patients With Upper GI Cancer Oral nutritional supplements with immunonutrition (enriched with arginine, nucleotides, vitamin D and omega-3-fatty acid), Standart of care - Upper GI Cancer | Not applicable | Enrolling by invitation | Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal | 110 | 2026-01-01 | 2026-10-20 |
| Omega-Cold Supplementation With Free Fatty Acids for the Prevention of Respiratory Infections in Adults. Omega-3 oil with 2% Free Fatty Acids, Vegatable oil - Respiratory Infections | Not applicable | Recruiting | Landspitali University Hospital | 400 | 2025-12-19 | 2026-08-28 |
| Regenerative Root Canal Treatment of Immature Teeth Using Omega-3 Fatty Acids Omega -3 fatty acids, Calcium Hydroxide (Ca(OH)2) - Immature Permanent Teeth With Open Apex, Pulp Necrosis | Not applicable | Active not recruiting | Mansoura University | 20 | 2025-10-01 | 2026-01-28 |
| Pilot Assessment of the Safety of a Combination of Curcumin, Omega-3, and Vitamin D Supplements in ACPA+ Individuals curcumin, omega-3, and vitamin D (COD) - Healthy Participants | Not applicable | Not yet recruiting | University of Manitoba | 50 | 2025-10-01 | 2025-08-01 |
| Omega-3 Fatty Acids in Muscle Function and Health Omega-3, Placebo comparator - Healthy | Not applicable | Not yet recruiting | European University Cyprus | 32 | 2025-09-01 | 2025-08-21 |
| Toripalimab, Induction Chemotherapy, Radiation Therapy With Omega-3 for Locally Advanced Nasopharyngeal Carcinoma Toripalimab, Omega-3, radiotherapy - Nasopharyngeal Carcinoma (NPC) | Phase 2 | Not yet recruiting | Affiliated Hospital of Guangdong Medical University | 30 | 2025-08-22 | 2025-08-22 |
| Differential Thrombogenesis by EPA and DHA Mediated by HDL EPA, DHA - Lipid Metabolism Disorders, Hypertriglyceridemia | Early Phase 1 | Recruiting | The Miriam Hospital | 80 | 2025-07-10 | 2025-10-01 |
| ICOPE INTENSE-K Pilot Study ICOPE intense intervention, Ketone Ester (KE) supplementation, Placebo - Ageing | Not applicable | Recruiting | University Hospital, Toulouse | 40 | 2025-07-09 | 2025-07-23 |
| Exploring Sustainable Alternatives to Marine Oils With Echium and Ahiflower Oils Echium oil, Ahiflower oil, EPA capsules - Cardiovascular (CV) Risk, Atheroscleroses | Not applicable | Active not recruiting | University of Sao Paulo | 15 | 2025-05-26 | 2025-12-17 |
| Effects of Omega-3 Fatty Acids on Acute Graft-versus-Host Disease After Allogeneic Stem Cell Transplantation. Omega-3 Lipid Emulsion - Graft-Versus-Host Disease(GVHD) | Phase 1 / Phase 2 | Enrolling by invitation | Fujian Medical University | 30 | 2025-05-16 | 2025-11-18 |
| Effect of Omega-3 Supplementation on Pregnant Outcomes and Inflammation Markers of Women Infected With HIV Using Antiretroviral Therapy omega-3 polyunsaturated fatty acids (PUFA n-3), Olive oil (placebo) - Pregnant HIV Positive Women | Not applicable | Enrolling by invitation | Instituto Nacional de Perinatologia Isidro Espinosa de los Reyes | 92 | 2025-05-14 | 2025-09-11 |
| Effect of Omega-3 Supplementation as Add on Therapy on Metabolic Syndrome in Women With Polycystic Ovary Syndrome. Omega 3 fatty acids, Omega -3 fatty acids - PCOS (Polycystic Ovary Syndrome) | Not applicable | Enrolling by invitation | Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh | 68 | 2025-04-22 | 2025-07-24 |
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Inflammation (29) · Obesity (19) · Cardiovascular Diseases (13) · Breast Neoplasms (11) · Depression (11) · Attention Deficit Disorder with Hyperactivity (9) · Diabetes Mellitus, Type 2 (9) · Non-alcoholic Fatty Liver Disease (8) · Depressive Disorder, Major (7) · Insulin Resistance (7) · Motor Activity (7) · Premature Birth (7) · Sarcopenia (7) · Cognitive Dysfunction (6) · Coronary Artery Disease (6)
Brigham and Women's Hospital (7) · Coordinación de Investigación en Salud, Mexico (7) · Tehran University of Medical Sciences (6) · University of Manitoba (6) · American Regent, Inc. (5) · Mayo Clinic (5) · University of Cincinnati (5) · Ain Shams University (3) · Cairo University (3) · China Medical University Hospital (3) · Loughborough University (3) · Massachusetts General Hospital (3) · Retina Foundation of the Southwest (3) · Texas Tech University (3) · The University of New South Wales (3)
United States (121) · Canada (27) · Brazil (16) · Egypt (15) · Spain (14) · China (10) · Iran (10) · Italy (10) · Mexico (10) · United Kingdom (10) · Norway (9) · France (8) · Taiwan (8) · Chile (5) · Germany (5)
Mariela Bernabe-Garcia, PhD (3) · Mark A Falone, MD (3) · Ahmed F Mahmoud Hussein, MS.c (2) · Daisuke Nishi, M.D., Ph.D. (2) · Gordon B Parker, Dsc MD PhD (2) · Kathleen Gustafson, PhD (2) · Kuan-Pin Su, M.D., Ph.D. (2) · Lynsey S Wilson, MSc (2) · Marcelo J Amar, M.D. (2) · Mauro Santamaria, Professor (2) · Melanie Plourde, PhD (2) · Pei-Chen Chang, MD, PhD (2) · Robert McNamara, PhD (2) · Sarah Keim, PhD (2)
PMID 34817851, PMID 37058600, PMID 31004139, PMID 37702300, PMID 10816186, PMID 12112073, PMID 15290734, PMID 15364708, PMID 15364709, PMID 15643744, PMID 16324089, PMID 16530201, PMID 17684201, PMID 18156400, PMID 18234997, PMID 18327998, PMID 18421079, PMID 18541599, PMID 19056592, PMID 19064745, PMID 19249410, PMID 19328438, PMID 19331677, PMID 19843899, PMID 20130094, PMID 20213818, PMID 20393114, PMID 20498621, PMID 20520307, PMID 20572767, PMID 20597641, PMID 20631232, PMID 20683766, PMID 21045096, PMID 21233083, PMID 21303552, PMID 21502576, PMID 21665007, PMID 21720194, PMID 21742090, PMID 21775114, PMID 21999398, PMID 22000478, PMID 22136711, PMID 22640930, PMID 22686415, PMID 22686416, PMID 22751375, PMID 22821626, PMID 22879423
2009 (2), 2019 (2), R01HD047315 (2), 1RC2AG036535 (1), 2008 (1), 2016 (1), 5UL1TR000135 (1), KL2TR000136 (1), N01CN00034 (1), N01CN35159 (1), P30CA016672 (1), P30CA069533 (1), P30ES009089 (1), R01AG029562 (1), R01AG054454 (1)