20 completed, 9 unknown, 7 recruiting, 4 terminated. 20 Not applicable, 11 Phase 4, 2 Phase 2, 1 Phase 3.
Follow Spine Fusion: new trials by email Literature Review of Spine Fusion trials Research Report on Spine Fusion
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Suzetrigine (Journavx) for Pain Management After Spine Surgery Suzetrigine (Journavx) - Spine Fusion, Postoperative Pain | Phase 4 | Not yet recruiting | Ohio State University | 110 | 2026-09-13 | 2026-09-21 |
| Rate of Bone Union After Surgery With Stand-alone Fibergraft Questionnaires, Computer Tomography - Spine Degeneration, Spine Disorder | Not yet recruiting | AO Innovation Translation Center | 80 | 2025-10-31 | 2025-09-30 | |
| Trans-Auricular Stimulation for Postoperative Inflammation in Spine Surgery Auricular vagus nerve stimulation, Sham Auricular Vagus nerve Stimulation - Spinal Fusion, Hyperglycemia | Not applicable | Recruiting | Alexander T. Yahanda | 50 | 2025-10-08 | 2026-08-18 |
| Effect of Magnesium on Neuromonitoring Magnesium sulfate administration - Spine, Pain | Phase 4 | Recruiting | University of California, San Francisco | 40 | 2025-07-01 | 2026-08-21 |
| Steroids After Spine Fusion Surgery Prednisone 20 Mg - Spine Fusion | Phase 4 | Unknown | Oregon Health and Science University | 420 | 2025-03-01 | 2024-04-22 |
| Ostene in Thoracolumbar Decompression and Fusion Evaluated With VIBE Ostene - Intraoperative Complications, Intraoperative Bleeding | Enrolling by invitation | University of Maryland, Baltimore | 173 | 2025-01-17 | 2026-09-04 | |
| Post Marketing Study of MagnetOs Easypack Putty Standalone Compared to Demineralized Bone Matrix or Fibers Mixed With Autograft in Patients Undergoing Posterolateral Lumbar Fusion MagnetOs Easypack Putty, Demineralized Bone Matrix or Fibers mixed with local autograft bone - Degenerative Disc Disease, Spine Fusion | Not applicable | Recruiting | Kuros Biosurgery AG | 60 | 2024-12-06 | 2026-03-20 |
| Evaluation of Surgical Treatment of Idiopathic Scoliosis With Vertebral Body Tethering Versus Posterior Spinal Fusion. gait analysis - Scoliosis; Adolescence, Spine Fusion | Completed | Istituto Ortopedico Rizzoli | 12 | 2024-11-22 | 2026-03-04 | |
| Randomized Controlled Comparison of Pre-op TLIP vs Intra-op TLIP Preoperative Ultrasound TLIP, Intraoperative TLIP - Pain, Spine Fusion | Not applicable | Withdrawn | Corewell Health East | 2024-10-28 | 2025-10-23 | |
| Spine Surgery Video Observation Study. The Creation of a Benchmark Video (RGB-Depth) Dataset to Investigate the Feasibility of Developing a Markerless Tracking System for Spine Surgery. Spine surgery - Spine Fusion, Spine Injury | Not yet recruiting | Imperial College London | 25 | 2024-10-01 | 2024-08-30 | |
| Titanium vs. PEEK Fusion Devices in 1 Level TLIF Titanium Fusion Device, PEEK Fusion Device - Spine Fusion, Lumbar Spondylolisthesis | Phase 4 | Enrolling by invitation | Twin Cities Spine Center | 80 | 2024-09-01 | 2025-06-24 |
| PeriOPerative Spine Surgery COntrol Pain (POPSSCOP) Study: Intrathecal Morphine vs Erector Spinae Plane Block for Postoperative Pain Management in Spinal Fusion Spine Fusion, Locoregional Anaesthesia | Completed | A.O.U. Città della Salute e della Scienza | 50 | 2024-08-30 | 2025-11-24 | |
| Erector Spinae Plane Block for Cervical Spine Surgery 0.9%sodium chloride, 0.2% ropivacaine - Spine Fusion, Spine Disease | Phase 4 | Completed | Poznan University of Medical Sciences | 60 | 2024-07-15 | 2026-02-02 |
| Pain Control After Lumbar Spine Fusion Naproxen 500 Mg, Ketorolac, OxyCODONE 5 mg Oral Tablet - Spine Fusion, NSAID (Non-Steroidal Anti-Inflammatory Drug) | Phase 4 | Unknown | Rothman Institute Orthopaedics | 428 | 2024-06-28 | 2024-07-03 |
| MagnetOs Flex Matrix Compared to Trinity Elite Mixed With Local Autograft in Patients Undergoing up to Four-level Instrumented Posterolateral Fusion MagnetOs Flex Matrix, Trinity Elite - Degenerative Disc Disease, Spine Fusion | Not applicable | Recruiting | Kuros Biosurgery AG | 100 | 2024-06-10 | 2026-10-19 |
| Pre-operative Risk Assessment Combined With Targeted Intervention in the Chinese Elderly With Spine Surgery Multimodal prehabilitation combined with perioperative ERAS care（PREERAS） - Spine Degeneration, Spine Fusion | Not applicable | Completed | Xuanwu Hospital, Beijing | 164 | 2024-04-15 | 2025-09-23 |
| Goal-directed vs Preemptive Tranexamic Acid Administration in Non-cardiac Surgery TXA, TEG6 - Arthritis Knee, Spine Fusion | Phase 4 | Unknown | Konkuk University Medical Center | 148 | 2024-02-10 | 2024-05-14 |
| Erector Spinae Plane Block in Spine Surgeries for Postoperative Pain Erector Spinae Plane Block using 0.25 % bupivacaine - Spine Fusion, Spine Metastases | Not applicable | Completed | Ain Shams University | 50 | 2023-12-31 | 2025-05-22 |
| Effect of Ketamine on Intraoperative Motor Evoked Potentials Ketamine - Spine Fusion, Spine Tumor | Phase 3 | Recruiting | University of California, San Francisco | 20 | 2023-12-01 | 2025-05-07 |
| Utility of Exparel Based ESP Blocks in Elective Posterior Spine Fusion Liposomal bupivacaine, Bupivacaine - Spine Fusion, Anesthesia, Local | Phase 4 | Unknown | Hartford Hospital | 100 | 2023-12-01 | 2023-10-30 |
Showing 20 of 47. Sign in to see all of them.
Pain, Postoperative (8) · Spinal Diseases (5) · Intervertebral Disc Degeneration (4) · Spinal Stenosis (4) · Pain (3) · Postoperative Complications (2) · Spondylolisthesis (2) · Agnosia (1) · Back Pain (1) · Blood Loss, Surgical (1) · Bone Diseases, Metabolic (1) · Cognitive Dysfunction (1) · Constriction, Pathologic (1) · Delirium (1) · Emergence Delirium (1)
Pathological Conditions, Signs and Symptoms (18) · Signs and Symptoms (15) · Bone Diseases (14) · Musculoskeletal Diseases (14) · Neurologic Manifestations (14) · Pathologic Processes (12) · Pain (9) · Postoperative Complications (8) · Spinal Diseases (8) · Nervous System Diseases (4) · Back Injuries (2) · Metabolic Diseases (2) · Neurobehavioral Manifestations (2) · Nutritional and Metabolic Diseases (2) · Pathological Conditions, Anatomical (2)
Bupivacaine (2) · Ketamine (2) · Ketorolac (2) · Lidocaine (2) · Oxycodone (2) · Sodium Chloride (2) · Administration, Sublingual (1) · Denosumab (1) · Esketamine (1) · Gait Analysis (1) · Injections, Subcutaneous (1) · Ketorolac Tromethamine (1) · Naproxen (1) · Prednisone (1) · Rehabilitation (1)
Kuros Biosurgery AG (3) · Ain Shams University (2) · Rothman Institute Orthopaedics (2) · Stanford University (2) · University of California, San Francisco (2) · University of Maryland, Baltimore (2) · A.O.U. Città della Salute e della Scienza (1) · AO Innovation Translation Center (1) · Aesculap AG (1) · Alexander T. Yahanda (1) · Assiut University (1) · Ataturk University (1) · Augmedics (1) · Bonalive Biomaterials Ltd (1) · Brigham and Women's Hospital (1)
United States (22) · China (3) · Turkey (Türkiye) (3) · Egypt (2) · Germany (2) · Italy (2) · Netherlands (2) · Australia (1) · Finland (1) · France (1) · Israel (1) · Poland (1) · Russia (1) · South Korea (1) · Vietnam (1)
Aleksandr Talypov, MD, PhD (1) · Amy M Cizik, MPH, PhC (1) · Andrey Grin, MD, PhD (1) · Anton Kordonskiy, MD, PhD (1) · Bryan Ladd, MD (1) · Cesar Silva, MD (1) · Chun-De Li (1) · Corinna Zygourakis, MD (1) · Daniel Park, MD (1) · Dong-Xin Wang, MD, PhD (1) · Heeren Makanji, MD (1) · Hemra Cil, MD (1) · Henk Van Santbrink, Md, PhD, Professor (1) · Iren Pogonchenkova, MD, PhD (1)
PMID 32053113, PMID 37955445, PMID 39663170, PMID 41115102, PMID 42296500, PMID 42812328
R21AR068009 (1), U01TR003719 (1)