10 completed, 4 recruiting, 4 unknown, 1 suspended. 20 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 20 | Completed 10, Recruiting 4, Unknown 4, Suspended 1, Withdrawn 1 |
Follow Spine Fusion: new trials by email Literature Review of Spine Fusion trials Research Report on Spine Fusion
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Trans-Auricular Stimulation for Postoperative Inflammation in Spine Surgery Auricular vagus nerve stimulation, Sham Auricular Vagus nerve Stimulation - Spinal Fusion, Hyperglycemia | Not applicable | Recruiting | Alexander T. Yahanda | 50 | 2025-10-08 | 2026-08-18 |
| Post Marketing Study of MagnetOs Easypack Putty Standalone Compared to Demineralized Bone Matrix or Fibers Mixed With Autograft in Patients Undergoing Posterolateral Lumbar Fusion MagnetOs Easypack Putty, Demineralized Bone Matrix or Fibers mixed with local autograft bone - Degenerative Disc Disease, Spine Fusion | Not applicable | Recruiting | Kuros Biosurgery AG | 60 | 2024-12-06 | 2026-03-20 |
| Randomized Controlled Comparison of Pre-op TLIP vs Intra-op TLIP Preoperative Ultrasound TLIP, Intraoperative TLIP - Pain, Spine Fusion | Not applicable | Withdrawn | Corewell Health East | 2024-10-28 | 2025-10-23 | |
| MagnetOs Flex Matrix Compared to Trinity Elite Mixed With Local Autograft in Patients Undergoing up to Four-level Instrumented Posterolateral Fusion MagnetOs Flex Matrix, Trinity Elite - Degenerative Disc Disease, Spine Fusion | Not applicable | Recruiting | Kuros Biosurgery AG | 100 | 2024-06-10 | 2026-10-19 |
| Pre-operative Risk Assessment Combined With Targeted Intervention in the Chinese Elderly With Spine Surgery Multimodal prehabilitation combined with perioperative ERAS care（PREERAS） - Spine Degeneration, Spine Fusion | Not applicable | Completed | Xuanwu Hospital, Beijing | 164 | 2024-04-15 | 2025-09-23 |
| Erector Spinae Plane Block in Spine Surgeries for Postoperative Pain Erector Spinae Plane Block using 0.25 % bupivacaine - Spine Fusion, Spine Metastases | Not applicable | Completed | Ain Shams University | 50 | 2023-12-31 | 2025-05-22 |
| Examination of the Effect of Early Mobilization on Postoperative Recovery, Pain, Quality of Life and Complication Development in Elective Minimally Invasive Spine Surgery intervention group - Spine Fusion, Lumbar Disc Herniation | Not applicable | Suspended | Duzce University | 96 | 2023-11-27 | 2024-08-09 |
| Fusion Status After ACDF Anterior Cervical Disc Fusion (ACDF) Surgery w/ machined bone allograft, Anterior Cervical Disc Fusion (ACDF) Surgery w/ Iliac Crest Bone Graft - Spine Fusion, Spine Surgery | Not applicable | Unknown | Rothman Institute Orthopaedics | 124 | 2023-08-07 | 2023-08-14 |
| Effectiveness of Combining Erector Spinea Block With Non Opioid Infusions as Opioid Free Anesthesia in Spine Surgeries. fentanyl infusion after general anesthesia and erector spinea block, lidocaine 2% and dextometometidine infusion after general anesthesia and erector spinea block - Opioid Use, Spine Fusion | Not applicable | Unknown | Ain Shams University | 140 | 2023-05-01 | 2023-05-09 |
| Personalized Perioperative Analgesia Platform (PPAP) for Pediatric Spine Fusion Surgery (sIRB) Preoperative Genotyping - PPAP, Spine Fusion | Not applicable | Recruiting | Senthil Sadhasivam | 300 | 2022-09-20 | 2026-09-10 |
| Long-term Follow-up Motion Analysis of ACD Versus ACDA Motion Analysis - Cervical Myelopathy, Cervical Radiculopathy | Not applicable | Completed | Zuyderland Medisch Centrum | 20 | 2022-02-12 | 2023-01-27 |
| TLIP Block and ESP Block For Perioperative Analgesia In Patients With Lumbar Spine Fusion Surgery TLIP Block For Perioperative Analgesia In Patients With Lumbar Spine Fusion Surgery, ESP Block For Perioperative Analgesia In Patients With Lumbar Spine Fusion Surgery, Lidocaine injection - Analgesia, Spine Fusion | Not applicable | Completed | Hanoi Medical University | 100 | 2021-10-01 | 2023-10-13 |
| Post Marketing Study of MagnetOs Putty Compared to Local Autograft in Patients Undergoing Posterolateral Lumbar Fusion MagnetOs Putty - Degenerative Disc Disease, Spine Fusion | Not applicable | Completed | Kuros Biosurgery AG | 30 | 2021-08-13 | 2024-02-13 |
| The Role of Bone SPECT/CT in Evaluation of Persistent or Recurrent Back Pain Following Spine Surgery spine surgeries - Spine Fusion | Not applicable | Unknown | Assiut University | 4 | 2021-04-01 | 2021-03-17 |
| Anterior Gen Plus Study Anterior Lumbar Interbody Fusion (ALIF) - Spine Fusion | Not applicable | Unknown | SeaSpine, Inc. | 8 | 2020-09-15 | 2023-04-04 |
| Improving Spine Surgical Care With Real-Time Objective Patient Tracking Using the Apple Watch Apple Watch and App - Spine Disease, Spine Degeneration | Not applicable | Completed | Stanford University | 255 | 2020-09-01 | 2025-12-19 |
| Denosumab Effect on Bone Quality and Function After Lumbar Fusion Surgery Denosumab, Placebo - Osteopenia, Spine Fusion | Not applicable | Completed | Shenzhen People's Hospital | 76 | 2020-01-12 | 2023-01-18 |
| Does Preoperative Pain Medication Management Influence Surgical Outcomes in Spinal Fusion Spinal Fusion Preoperative Opioid Taper, Non-taper Control - Opioid Use, Spine Fusion | Not applicable | Completed | Stanford University | 16 | 2019-09-09 | 2025-04-11 |
| Effect of Introperative Ketamine and Lidocaine Infusion on Postoperative Opioid Consumption in Posterior Spinal Fusion Surgery Ketamine, Lidocain, Saline - Spine Fusion, Postoperative Pain | Not applicable | Completed | Ataturk University | 75 | 2019-05-29 | 2021-01-15 |
| Pedicle Screw Placement With XVS xvision Spine sytem - Spine Fusion | Not applicable | Completed | Augmedics | 19 | 2018-05-20 | 2021-08-24 |
Intervertebral Disc Degeneration (3) · Pain, Postoperative (3) · Spinal Diseases (3) · Pain (2) · Spinal Stenosis (2) · Agnosia (1) · Back Pain (1) · Bone Diseases, Metabolic (1) · Frailty (1) · Hyperglycemia (1) · Inflammation (1) · Intervertebral Disc Displacement (1) · Nervous System Diseases (1) · Neurologic Manifestations (1) · Postoperative Complications (1)
Bone Diseases (8) · Musculoskeletal Diseases (8) · Pathological Conditions, Signs and Symptoms (8) · Signs and Symptoms (7) · Neurologic Manifestations (6) · Pain (4) · Pathologic Processes (4) · Spinal Diseases (4) · Metabolic Diseases (2) · Nervous System Diseases (2) · Nutritional and Metabolic Diseases (2) · Postoperative Complications (2) · Glucose Metabolism Disorders (1) · Hernia (1) · Neurobehavioral Manifestations (1)
Lidocaine (2) · Bupivacaine (1) · Denosumab (1) · Injections, Subcutaneous (1) · Ketamine (1) · Sodium Chloride (1)
Kuros Biosurgery AG (3) · Ain Shams University (2) · Stanford University (2) · Alexander T. Yahanda (1) · Assiut University (1) · Ataturk University (1) · Augmedics (1) · Corewell Health East (1) · Duzce University (1) · Hanoi Medical University (1) · Rothman Institute Orthopaedics (1) · SeaSpine, Inc. (1) · Senthil Sadhasivam (1) · Shenzhen People's Hospital (1) · Xuanwu Hospital, Beijing (1)
United States (10) · China (2) · Egypt (2) · Turkey (Türkiye) (2) · Israel (1) · Netherlands (1) · Vietnam (1)
Cesar Silva, MD (1) · Chun-De Li (1) · Corinna Zygourakis, MD (1) · Daniel Park, MD (1) · Henk Van Santbrink, Md, PhD, Professor (1) · Muwaffak Abdulhak, MD (1) · Pascal Longlade, MD (1) · Senthilkumar Sadhasivam, MD, MPH (1) · Serena Hu, MD (1) · Shibao Lu (1) · Shuaikang Wang (1) · Tu Nguyen, Professor (1) · Yong Yang (1)
PMID 37955445, PMID 39663170, PMID 42296500
U01TR003719 (1)