20 completed. 20 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 20 | Completed 20 |
Follow Pain Management: new trials by email Literature Review of Pain Management trials Research Report on Pain Management
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effectiveness of Curcuminoids in Controlling Postoperative Pain Following Total Laparoscopic Hysterectomy liposomal curcumin - Postoperative Care, Pain Management | Phase 4 | Completed | Erzincan Military Hospital | 126 | 2025-03-21 | 2026-04-02 |
| ORAL AND INTRA - LIGAMENTARY PIROXICAM for Post Endodontic Pain Management intra-ligamentary - Pain Management, Post Endodontic Pain | Phase 4 | Completed | Pakistan Institute of Medical Sciences | 50 | 2023-05-27 | 2026-07-20 |
| Topical Lidocaine 23%/Tetracaine 7% Ointment for Post-Hemorrhoidectomy Analgesia: A Randomized Controlled Trial Lidocaine 23% / Tetracaine 7% topical ointment (compounded), Placebo ointment - Pain Management, Hemorrhoids Third Degree | Phase 4 | Completed | Pontificia Universidad Catolica de Chile | 74 | 2023-05-24 | 2026-07-07 |
| "Management of Low Back Pain in the Emergency Department With Different Analgesic Dosages" Ibuprofen 400 mg, Ibuprofen 800 mg - Low Back Pain, Mechanical, Ibuprofen | Phase 4 | Completed | Ankara City Hospital Bilkent | 144 | 2022-01-01 | 2023-10-03 |
| Multi-Modal Anesthesia Protocol in Pain Management of Patients Undergoing Posterior Lumbar Spinal Fusion Surgery Toradol, Morphine, Orphenadrine - Pain Management, Posterior Spinal Fusion | Phase 4 | Completed | University of Puerto Rico | 100 | 2021-04-05 | 2022-06-10 |
| Pain Experience Using Lidocaine Adrenaline Tetracaine (LAT) Gel Versus Lidocaine Infiltration for Laceration Repair in Adults Lidocaine-Adrenaline-Tetracaine (LAT) Gel, Lidocaine infiltration - Lacerations, Wound Repair | Phase 4 | Completed | Vrije Universiteit Brussel | 70 | 2021-04-01 | 2026-03-18 |
| Ibuprofen and Neural Mobilization Treatment in Carpal Tunnel Syndrome. ibuprofen tablets, Median nerve neural mobilization - Carpal Tunnel Syndrome, Ibuprofen | Phase 4 | Completed | Universidad Europea de Madrid | 123 | 2020-09-23 | 2025-12-11 |
| Regional Block for Postoperative Free Flap Care ropivicaine 0.2% - Pain Management | Phase 4 | Completed | University of Alabama at Birmingham | 100 | 2020-01-13 | 2023-12-06 |
| Intravenous Acetaminophen and Morphine Versus Intravenous Morphine Alone for Acute Pain in the Emergency Department placebo of acetaminophen IV, acetaminophen IV - Pain Management | Phase 4 | Completed | Nantes University Hospital | 415 | 2019-12-03 | 2025-01-13 |
| Pudendal Enhancement of Enhanced Recovery After Surgery (ERAS) for Reconstructive Surgery (PEERS) Local anaesthetic, Pudendal Nerve Block plus anesthesia - Pain Management | Phase 4 | Completed | University of California, Los Angeles | 44 | 2019-11-14 | 2025-06-03 |
| Regional Anesthesia to Reduce Opioid Use Following Functional Endoscopic Sinus Surgery Bupivacaine, Dexamethasone - Pain Management | Phase 4 | Completed | University of Alabama at Birmingham | 46 | 2019-05-20 | 2022-08-31 |
| LIBERATE - LIposomal Bupivacaine vERsus Adjuncts in Total shouldErs Liposomal Bupivicaine 1.3%, Bupivacaine 0.5% - Post-operative Pain, Total Shoulder Arthroplasty | Phase 4 | Completed | Hartford Hospital | 90 | 2019-03-11 | 2023-09-15 |
| Efficacy and Safety of EXPAREL Versus Standard of Care (SoC) in Subjects Undergoing Elective Cesarean Section 50 mcg Duramorph+ EXPAREL + multi-modal pain regimen, 150 mcg Duramorph + multi-modal pain regimen, Exparel TAP + multi-modal pain regimen - Elective Cesarean Section, Pain Management | Phase 4 | Completed | Pacira Pharmaceuticals, Inc | 167 | 2019-03-04 | 2022-07-18 |
| Comparison of Two Pain-treatment Techniques After Cesarean Section TAP (transversus abdominis plane block), QL (quadratus lumborum block), Bupivacaine - Cesarean Section, Pain Management | Phase 4 | Completed | Michał Borys | 232 | 2017-06-01 | 2023-11-28 |
| Evaluate the Safety and Efficacy of EXPAREL When Administered Via Infiltration Into the TAP vs. Bupivacaine Alone in Subjects Undergoing Elective C-Sections Exparel + Bupivacaine, Bupivacaine - C-Section, Pain Management | Phase 4 | Completed | Pacira Pharmaceuticals, Inc | 186 | 2017-06-01 | 2021-01-06 |
| Adductor Canal Block After Total Knee Replacement - a Suture-method Catheter vs a Standard Catheter vs a Single Bolus Initial bolus (Certa and standard catheter groups), Initial bolus (Single bolus group), Intermittent boluses (Certa and standard catheter groups) - Pain Management | Phase 4 | Completed | University Hospital, Gentofte, Copenhagen | 153 | 2017-05-09 | 2018-05-01 |
| Pre-emptive Analgesics in Orthodontic Treatment Acetaminophen, Ibuprofen - NSAID, Pain Management | Phase 4 | Completed | University of Washington | 73 | 2017-05-02 | 2019-08-21 |
| Mepivacaine vs. Bupivacaine Spinal Anesthetic in Total Knee Arthroplasty Mepivacaine, Bupivacaine - Anesthesia, Spinal, Arthroplasty, Replacement, Knee | Phase 4 | Completed | Henry Ford Health System | 32 | 2016-12-01 | 2017-03-27 |
| Serratus Plane Block For Breast Reduction Surgery Bupivacaine, Saline - Pain Management | Phase 4 | Completed | Ataturk University | 40 | 2016-07-01 | 2017-01-24 |
| Intrathecal Morphine Versus Epidural Extended Release Morphine for Pediatric Patients Undergoing Spinal Fusion Intrathecal morphine, Extended Release Epidural Morphine - Pain Management, Spinal Fusion | Phase 4 | Completed | University of Colorado, Denver | 84 | 2008-12-01 | 2020-04-22 |
Agnosia (20) · Pain (3) · Acute Pain (2) · Pain, Postoperative (2) · Carpal Tunnel Syndrome (1) · Chronic Pain (1) · Emergencies (1) · Lacerations (1) · Low Back Pain (1) · Neuralgia (1) · Scoliosis (1) · Wounds and Injuries (1)
Nervous System Diseases (20) · Neurobehavioral Manifestations (20) · Neurologic Manifestations (20) · Pathological Conditions, Signs and Symptoms (20) · Perceptual Disorders (20) · Signs and Symptoms (20) · Pain (6) · Pathologic Processes (3) · Neuromuscular Diseases (2) · Peripheral Nervous System Diseases (2) · Postoperative Complications (2) · Back Pain (1) · Bone Diseases (1) · Cumulative Trauma Disorders (1) · Disease Attributes (1)
Bupivacaine (6) · Acetaminophen (3) · Ibuprofen (3) · Morphine (3) · Epinephrine (2) · Analgesics, Opioid (1) · Anesthesia (1) · Anesthesia, Local (1) · Calcium Dobesilate (1) · Dexamethasone (1) · Dipyrone (1) · Gabapentin (1) · Gels (1) · Ketoprofen (1) · Ketorolac Tromethamine (1)
Pacira Pharmaceuticals, Inc (2) · University of Alabama at Birmingham (2) · Ankara City Hospital Bilkent (1) · Ataturk University (1) · Erzincan Military Hospital (1) · Hartford Hospital (1) · Henry Ford Health System (1) · Michał Borys (1) · Nantes University Hospital (1) · Pakistan Institute of Medical Sciences (1) · Pontificia Universidad Catolica de Chile (1) · Universidad Europea de Madrid (1) · University Hospital, Gentofte, Copenhagen (1) · University of California, Los Angeles (1) · University of Colorado, Denver (1)
United States (9) · Turkey (Türkiye) (3) · Belgium (1) · Chile (1) · Denmark (1) · France (1) · Pakistan (1) · Poland (1) · Puerto Rico (1) · Venezuela (1)
Ali Ahiskalioglu (1) · Anne-Marie Bollen, DDS, MS, PhD (1) · Anthony Morlandt, MD (1) · Brad Woodworth, MD (1) · Carlos Perez, MD (1) · Hassan Danesi (1) · Jason Davis, MD (1) · Kevin Finkel, MD (1) · Mindy Cohen, MD (1) · Miroslaw Czuczwar, MD, PhD (1) · Nayana Nagaraj, MD, PhD, MPH (1) · Ulrik Grevstad, MD, phd (1)
PMID 25520223, PMID 31465115, PMID 32739962, PMID 34626927, PMID 34986477, PMID 36522767, PMID 37192425, PMID 38640500, PMID 41733913