11 enrolling by invitation. 11 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 11 | Enrolling by invitation 11 |
Follow Pain: new trials by email Literature Review of Pain trials Research Report on Pain
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Suzetrigine for Non-Mastectomy Breast Surgery suzetrigine - Pain, Acute Postoperative, Breast Disease | Phase 4 | Enrolling by invitation | University of California, San Diego | 120 | 2026-04-14 | 2026-09-16 |
| Intravenous Acetaminophen and Ketorolac for Pain Management During Extracorporeal Shockwave Lithotripsy IV midazolam, IV fentanyl, IV acetaminophen - Extracorporeal Shockwave Lithotripsy | Phase 4 | Enrolling by invitation | Horizon Health Network | 266 | 2026-04-01 | 2026-04-13 |
| Efficacy And Safety Of Tramadol And Oxycodone Versus Oxycodone Monotherapy For Pain Control After Primary Total Knee And Total Hip Arthroplasty Oxycodone, Tramadol and Oxycodone - Post Operative Pain | Phase 4 | Enrolling by invitation | Mayo Clinic | 560 | 2026-02-02 | 2026-03-18 |
| Musculoskeletal Outcomes Using Tylenol/Ibuprofen vs. Oral Steroids in New Injuries Methylprednisolone 4Mg Tab, Acetaminophen 500Mg Tab, Ibuprofen 200Mg Oral Tablet - Musculoskeletal Pain | Phase 4 | Enrolling by invitation | State University of New York at Buffalo | 60 | 2025-09-17 | 2026-10-16 |
| Dexamethasone to Prevent Side Effects of Spinal Anesthesia in Cesarean Delivery Dexamethasone, Placebo - Hypotension During Cesarean Delivery, Postoperative Nausea and Vomiting (PONV) | Phase 4 | Enrolling by invitation | University Medical Center Ho Chi Minh City (UMC) | 176 | 2025-08-01 | 2026-05-29 |
| Effect of Perioperative Dexmedetomidine on Chronic Post-Surgical Pain Dexmedetomidine, Saline solution - Chronic Post-Surgical Pain | Phase 4 | Enrolling by invitation | Peking Union Medical College Hospital | 364 | 2025-07-01 | 2025-07-18 |
| Enhanced Recovery After Surgery (ERAS) in Live Donor Kidney Transplant Recipients pre-operative carbohydrate drink, Acetaminophen, Gabapentin - Postoperative Pain | Phase 4 | Enrolling by invitation | Baylor Research Institute | 60 | 2025-05-05 | 2026-10-15 |
| Comparative Analgesic Effect After Total Knee Arthroplasty Between Intraosseous and Peri-articular Injection Intraosseous Morphine, Periarticular Injection - Pain Postoperative, Total Knee Anthroplasty | Phase 4 | Enrolling by invitation | Thammasat University Hospital | 90 | 2024-09-01 | 2025-06-04 |
| Reducing Opioid Use After Upper Extremity Surgery: Testing Lower Prescriptions and Pill Quantity Naproxen, Acetaminophen, oxycodone - Opioid Abuse (Disorder), Opioid Analgesia | Phase 4 | Enrolling by invitation | AdventHealth | 300 | 2024-08-01 | 2026-10-08 |
| Low Dose Naltrexone Therapy for Complex Regional Pain Syndrome Low dose naltrexone, Placebo sugar capsules - Complex Regional Pain Syndrome, Chronic Pain | Phase 4 | Enrolling by invitation | Hospital for Special Surgery, New York | 40 | 2024-01-02 | 2026-06-18 |
| Pain Management Study Active Comparator: narcotic regimen with TAP block, Active Comparator: narcotic regimen with no TAP block, non-narcotic regimen with TAP block - Pain, Postoperative | Phase 4 | Enrolling by invitation | University of Arizona | 244 | 2022-02-18 | 2025-08-24 |
Pain, Postoperative (8) · Agnosia (1) · Bites and Stings (1) · Breast Diseases (1) · Causalgia (1) · Chronic Pain (1) · Complex Regional Pain Syndromes (1) · Musculoskeletal Pain (1) · Opioid-Related Disorders (1) · Postoperative Complications (1) · Postoperative Nausea and Vomiting (1)
Neurologic Manifestations (11) · Pathological Conditions, Signs and Symptoms (11) · Signs and Symptoms (11) · Pathologic Processes (8) · Postoperative Complications (7) · Chemically-Induced Disorders (2) · Autonomic Nervous System Diseases (1) · Mental Disorders (1) · Muscular Diseases (1) · Musculoskeletal Diseases (1) · Narcotic-Related Disorders (1) · Nausea (1) · Nervous System Diseases (1) · Neuralgia (1)
Acetaminophen (4) · Gabapentin (2) · Oxycodone (2) · Bupivacaine (1) · Dexamethasone (1) · Dexmedetomidine (1) · Fentanyl (1) · Ibuprofen (1) · Ketorolac (1) · Methylprednisolone (1) · Midazolam (1) · Naltrexone (1) · Naproxen (1) · Saline Solution (1) · Tablets (1)
AdventHealth (1) · Baylor Research Institute (1) · Horizon Health Network (1) · Hospital for Special Surgery, New York (1) · Mayo Clinic (1) · Peking Union Medical College Hospital (1) · State University of New York at Buffalo (1) · Thammasat University Hospital (1) · University Medical Center Ho Chi Minh City (UMC) (1) · University of Arizona (1) · University of California, San Diego (1)
United States (7) · Canada (1) · China (1) · Thailand (1) · Vietnam (1)
Alexandra Sideris, PhD (1) · Amir Kachooei, MD PhD (1) · Brian M Ilfeld, MD, MS (1) · Charles P. Hannon, MD, MBA (1) · Richard Ruiz, MD (1) · Semih Gungor, M.D. (1) · Thomas F Whelan, MD, FRCSC (1)