6 completed, 4 terminated, 2 recruiting, 2 unknown. 8 Not applicable, 2 Phase 2, 1 Phase 3, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 8 | Completed 4, Recruiting 1, Terminated 1, Unknown 1, Withdrawn 1 |
| Phase 2 | 2 | Terminated 2 |
| Phase 3 | 1 | Unknown 1 |
| Phase 4 | 1 | Enrolling by invitation 1 |
Follow Causalgia: new trials by email Literature Review of Causalgia trials Research Report on Causalgia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Prospective Case Series Evaluating 6-Month and 12-Month Outcomes After Cryoneurolysis for Chronic Pain Chronic Pain, PERIPHERAL NEUROPATHY | Recruiting | Yale University | 80 | 2026-06-20 | 2026-08-21 | |
| Perineural Incobotulinumtoxin-A for Complex Regional Pain Syndrome - An Open-label Feasibility Study Perineural Incobotulinumtoxin-A 200 U - CRPS (Complex Regional Pain Syndromes), CRPS (Complex Regional Pain Syndrome) Type I | Not applicable | Recruiting | Bo Biering-Soerensen | 20 | 2026-01-07 | 2026-03-16 |
| Sub-threshold DRG Stimulation vs Sham in Established Responders Subtreshhold DRG-S, Sham - Neuropathic Pain, Complex Regional Pain Syndromes (CRPS) | Not applicable | Completed | Umeå University | 20 | 2025-09-01 | 2025-12-05 |
| Low Dose Naltrexone Therapy for Complex Regional Pain Syndrome Low dose naltrexone, Placebo sugar capsules - Complex Regional Pain Syndrome, Chronic Pain | Phase 4 | Enrolling by invitation | Hospital for Special Surgery, New York | 40 | 2024-01-02 | 2026-11-06 |
| Volar Locking Plate Versus External Fixation for Distal Radius Fracture - a Longterm Follow up Volar locking plate, external fixation - Radius Fracture Distal, Surgery | Not applicable | Unknown | Olof Skoldenberg | 203 | 2022-04-01 | 2022-05-12 |
| Embodied Virtual Reality for Chronic Pain Embodied virtual reality - Complex Regional Pain Syndromes, Complex Regional Pain Syndrome Type I of the Upper Limb | Not applicable | Completed | University of Zurich | 29 | 2021-05-31 | 2024-10-18 |
| Trialing of ISS in Patients With CRPS Intraspinal-optimal stim therapy - CRPS I, Causalgia | Not applicable | Completed | Millennium Pain Center | 16 | 2019-06-13 | 2022-04-05 |
| Efficacy and Safety of a Learning Program of Self- Rehabilitation Exercises by Mirror Therapy Mirror therapy, Usual care - Reflex Sympathetic Dystrophy, Causalgia | Not applicable | Terminated | Centre Hospitalier Universitaire de Saint Etienne | 34 | 2017-06-06 | 2021-01-20 |
| The Effect of Transcranial Direct Current Stimulation (t-DCS) On the P300 Component of Event-Related Potentials in Patients With Chronic Neuropathic Pain Due To CRPS or Diabetic Neuropathy TDCS/sham procedure on five consecutive days - Diabetic Neuropathies, Complex Regional Pain Syndrome Type II | Not applicable | Withdrawn | Soroka University Medical Center | 2016-09-01 | 2017-10-05 | |
| Efficacy of Etoricoxib on Peripheral Hyperalgesia Etoricoxib, placebo - Causalgia, Polyneuropathy | Phase 2 | Terminated | Ruhr University of Bochum | 9 | 2011-02-01 | 2012-08-24 |
| Surgical Treatment Of Complex Regional Pain Syndrome Type II (CRPS II) SUBCUTANEOUS VENOUS SYMPATHECTOMY (RSVS) - CRPS Type II | Phase 3 | Unknown | Medical University of Vienna | 20 | 2009-01-01 | 2011-07-12 |
| Regional Anesthesia Military Battlefield Pain Outcomes Study Regional Anesthesia, Standard Pain Management Protocol - Anxiety Disorders, Complex Regional Pain Syndrome Type II | Completed | VA Office of Research and Development | 386 | 2007-10-01 | 2017-05-15 | |
| The Efficacy of Motor Cortex Stimulation for Pain Control motor cortex stimulation - Neuropathic Pain, Phantom Limb Pain | Not applicable | Completed | Nova Scotia Health Authority | 12 | 2005-10-01 | 2016-10-18 |
| Evoked Fields After Median and Ulnar Stimulation Evoked fields before and after a local block (Xylocaine) - Complex Regional Pain Syndromes | Completed | Medical Center Alkmaar | 60 | 2005-06-01 | 2009-09-18 | |
| Study of Proteins Associated With Complex Regional Pain Syndrome Complex Regional Pain Syndromes, Healthy | Terminated | National Institute of Nursing Research (NINR) | 120 | 2002-04-15 | 2019-12-12 | |
| Neurotropin to Treat Chronic Neuropathic Pain Placebo, Neurotropin - Complex Regional Pain Syndrome Type I, Complex Regional Pain Syndrome Type II | Phase 2 | Terminated | National Institute of Nursing Research (NINR) | 21 | 2000-09-01 | 2017-08-22 |
| Efficacy of Parecoxib on Patients With CRPS Parecoxib, Placebo - Causalgia | No longer available | Ruhr University of Bochum | 2012-04-25 |
Complex Regional Pain Syndromes (9) · Neuralgia (6) · Reflex Sympathetic Dystrophy (5) · Chronic Pain (4) · Pain (3) · Agnosia (2) · Anxiety Disorders (1) · Combat Disorders (1) · Depressive Disorder (1) · Diabetic Neuropathies (1) · Facial Pain (1) · Failed Back Surgery Syndrome (1) · Joint Dislocations (1) · Low Back Pain (1)
Autonomic Nervous System Diseases (17) · Nervous System Diseases (17) · Neuromuscular Diseases (17) · Peripheral Nervous System Diseases (16) · Neuralgia (11) · Pathological Conditions, Signs and Symptoms (11) · Neurologic Manifestations (10) · Signs and Symptoms (10) · Complex Regional Pain Syndromes (8) · Pain (7) · Neurobehavioral Manifestations (3) · Pathologic Processes (3) · Perceptual Disorders (3) · Postoperative Complications (3) · Arthritis (2)
Anesthesia, Conduction (1) · Etoricoxib (1) · External Fixators (1) · Lidocaine (1) · Mirror Movement Therapy (1) · Naltrexone (1) · neurotropin (1) · parecoxib (1) · salicylhydroxamic acid (1)
National Institute of Nursing Research (NINR) (2) · Ruhr University of Bochum (2) · Bo Biering-Soerensen (1) · Centre Hospitalier Universitaire de Saint Etienne (1) · Hospital for Special Surgery, New York (1) · Medical Center Alkmaar (1) · Medical University of Vienna (1) · Millennium Pain Center (1) · Nova Scotia Health Authority (1) · Olof Skoldenberg (1) · Soroka University Medical Center (1) · Umeå University (1) · University of Zurich (1) · VA Office of Research and Development (1) · Yale University (1)
United States (6) · Sweden (2) · Austria (1) · Canada (1) · Denmark (1) · France (1) · Germany (1) · Israel (1) · Netherlands (1) · Switzerland (1)
Alexandra Sideris, PhD (1) · Andrew J Mannes, M.D. (1) · Charles A Odonkor, MD (1) · Christoph Maier, Dr.med (1) · Leorey Saligan, PhD, CRNP (1) · Pedram Tabatabaei Tabatabaei, M.D, Ph.D (1) · Peter J Theuvenet, MD (1) · Ricardo Vallejo, MD,PhD (1) · Robert M Brownstone, MD, PhD (1) · Rollin M Gallagher, MD MPH (1) · Semih Gungor, M.D. (1) · Wolfgang Happak, Prof. MD (1)
PMID 16040256, PMID 16977490, PMID 26324857, PMID 31563880, PMID 38805527, PMID 42128597
2009 (2)