453 completed, 99 unknown, 70 recruiting, 46 not yet recruiting. 454 Not applicable, 39 Phase 2, 30 Phase 3, 26 Phase 4, 20 Phase 1.
Follow Musculoskeletal Pain: new trials by email Literature Review of Musculoskeletal Pain trials Research Report on Musculoskeletal Pain
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Personalizing Veteran Pain Care: Adapting Coaching Interventions to Support Maintenance of Self-Care Coaching - Chronic Pain, Musculoskeletal Pain | Phase 1 | Not yet recruiting | VA Office of Research and Development | 30 | 2029-01-01 | 2026-03-06 |
| Effects of Hydrogen-rich Water Consumption on Transient Fatigue During an Official Football Match. Hydrogen-Rich Water (HRW), Placebo Water - Exercise-Induced Fatigue, Football Performance | Not applicable | Not yet recruiting | Palacky University | 30 | 2027-01-20 | 2026-10-08 |
| Regenerative Medicine for Joint Hypermobility and Instability Dextrose 20% Prolotherapy, Autologous Platelet-Rich Plasma, Doxycycline Hyclate Injectable (Investigational) - Ehlers-Danlos Syndrome Hypermobility Type (hEDS), Ehlers-Danlos Syndrome (EDS) | Phase 1 / Phase 2 | Not yet recruiting | Manhattan Pain Medicine, PLLC | 100 | 2027-01-15 | 2026-10-06 |
| FIBROmyalgia: Somatic Tracking and Exercise Program Study Group exercising, Somatic tracking, General activity recommendaitons - Fibromyalgia (FM), Fibromyalgia | Not applicable | Not yet recruiting | University of Tromso | 200 | 2027-01-01 | 2025-05-13 |
| Multicomponent Exercise and Pain Science Education for Fall Prevention in Older Adults With Chronic Musculoskeletal Pain (MovePainFall) MovePainFall multicomponent exercise programme, Pain science and fall-prevention education - Chronic Pain, Musculoskeletal Pain | Not applicable | Not yet recruiting | Instituto Politécnico de Bragança | 40 | 2026-11-02 | 2026-10-27 |
| Therapeutic Ultrasound for Muscle Recovery After Muscle Fatigue Exercise Pulsed Low-Intensity Therapeutic Ultrasound, Placebo Therapeutic Ultrasound - Muscle Fatigue (C23.888.592.612.612), Delayed Onset Muscle Soreness (DOMS) | Not applicable | Not yet recruiting | Universidade Federal de Santa Maria | 30 | 2026-11-01 | 2026-10-13 |
| Evaluation of the Effect of Adding Sodium Bicarbonate to Lidocaine in the Treatment of Myofascial Pain Syndrome Lidocaine 2 %, Lidocaine + Sodium Bicarbonate - Myofacial Pain, Myofacial Pain Syndrome | Not applicable | Recruiting | Cairo University | 30 | 2026-11-01 | 2026-10-21 |
| Veterans' Intervention Blending NeuRomodulation and YogA for Chronic Low BackPaiN Treatment: VIBRANT intermittent theta burst stimulation, LoveYourBrain Yoga Program - Chronic Low Back Pain, Musculoskeletal Pain | Phase 3 | Not yet recruiting | VA Office of Research and Development | 213 | 2026-10-30 | 2026-10-26 |
| Daily Knee Sleeve Use Versus No Use in Older Adults With Chronic Knee Pain Knee sleeve - Knee Arthritis, Osteoarthritis | Not applicable | Recruiting | Margaret L Gourlay, MD, MPH | 235 | 2026-10-21 | 2026-10-27 |
| Pain Phenotype and Response to Corticosteroid Injection in Patients With Subacromial Pain Syndrome (SAPS) Clinical evaluation - Subacromial Pain Syndrome, Rotator Cuff Related Shoulder Pain | Recruiting | Vejle Hospital | 134 | 2026-10-19 | 2026-10-23 | |
| Nociplastic Pain in Patients Diagnosed With Subacromial Pain Syndrome (SAPS) Clinical evaluation - Subacromial Pain Syndrome, Rotator Cuff Related Shoulder Pain | Recruiting | Vejle Hospital | 400 | 2026-10-19 | 2026-10-23 | |
| Comparison of High-Intensity and Conventional Physical Therapy in Musculoskeletal Disorders Repetitive Peripheral Magnetic Stimulation (rPMS), High-Intensity Laser Therapy (HIL), Extracorporeal Shockwave Therapy (ESWT) - Low Back Pain, Radicular Syndrome | Not applicable | Not yet recruiting | BTL Industries Ltd. | 60 | 2026-10-15 | 2026-10-29 |
| A Study to Evaluate the Analgesic Properties of Topically Applied Menthol in Marathon Participants Observational, Non-Interventional Study - Muscle Soreness | Not yet recruiting | Reckitt Benckiser Healthcare (UK) Limited | 600 | 2026-10-11 | 2026-10-16 | |
| Biopsychosocial Risk Influences on the Development and Generation of Early-Onset Chronic Pain Not applicable- observational study - Juvenile Idiopathic Arthritis (JIA), Fibromyalgia | Recruiting | Children's Hospital Medical Center, Cincinnati | 600 | 2026-10-01 | 2026-10-16 | |
| Empowered Relief for Caregivers Empowered Relief for Caregivers (ER-CY) - Chronic Pain, Musculoskeletal Pain | Not applicable | Not yet recruiting | Stanford University | 80 | 2026-10-01 | 2026-08-20 |
| Transcutaneous Auricular Vagus Nerve Stimulation as a Treatment for Musculoskeletal Pain in Cerebral Palsy Active Transcutaneous Auricular Vagus Nerve Stimulation, Sham Transcutaneous Auricular Vagus Nerve Stimulation - Cerebral Palsy (CP), Musculoskeletal Pain | Not applicable | Not yet recruiting | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | 32 | 2026-10-01 | 2026-05-13 |
| Physical Activity in Lawyers: Factors Affecting Musculoskeletal Pain Musculoskeletal Pain, Physical Activity | Not yet recruiting | Suleyman Demirel University | 102 | 2026-09-30 | 2026-09-24 | |
| Exercise and Health Education for Musculoskeletal Health in Industrial Workers Health Education, Tailored Exercise Programme - Work-Related Musculoskeletal Disorders | Not applicable | Recruiting | Universidad San Jorge | 33 | 2026-09-22 | 2026-10-02 |
| Light Bulb Stimuli to Reduce Chronic Pain S-Cone Stimulating Chromatic Light, Equal-Energy White Light - Fibromyalgia, Musculoskeletal Pain | Not applicable | Not yet recruiting | University of North Carolina, Chapel Hill | 40 | 2026-09-21 | 2026-09-17 |
| The Effects of Tyrosol and Creatine on Exercise Performance and Cognition in Healthy Adults Tyrosol, Creatine Monohydrate, Resistant Dextrin - Tyrosol, Creatine | Not applicable | Recruiting | Applied Science & Performance Institute | 60 | 2026-09-04 | 2026-09-21 |
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Myalgia (211) · Chronic Pain (114) · Pain (79) · Pelvic Girdle Pain (59) · Low Back Pain (57) · Neck Pain (53) · Motor Activity (39) · Musculoskeletal Diseases (34) · Arthralgia (31) · Back Pain (28) · Shoulder Pain (24) · Fibromyalgia (23) · Agnosia (21) · Headache (21)
Neurologic Manifestations (735) · Pathological Conditions, Signs and Symptoms (735) · Signs and Symptoms (734) · Muscular Diseases (669) · Pain (656) · Musculoskeletal Diseases (647) · Nervous System Diseases (284) · Neuromuscular Diseases (239) · Joint Diseases (104) · Behavior (87) · Pathologic Processes (61) · Pelvic Pain (55) · Mental Disorders (50) · Back Pain (48)
Exercise (16) · Ibuprofen (9) · Acetaminophen (8) · Cognitive Behavioral Therapy (8) · Surveys and Questionnaires (8) · Yoga (8) · Resistance Training (7) · Therapeutics (7) · Control Groups (6) · Cryotherapy (5) · Dry Needling (5) · Transcutaneous Electric Nerve Stimulation (5) · Watchful Waiting (5) · maltodextrin (5) · Athletic Tape (4)
Riphah International University (17) · VA Office of Research and Development (12) · University of Florida (9) · University of North Carolina, Chapel Hill (8) · Aalborg University (7) · Oslo Metropolitan University (6) · Cairo University (5) · Children's Hospital Medical Center, Cincinnati (5) · Indiana University (5) · Stanford University (5) · Universidad San Jorge (5) · Uskudar University (5) · Erchonia Corporation (4) · Hacettepe University (4) · Hasselt University (4)
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Laura Simons, PhD (4) · Alejandro Luque Suarez, PhD (3) · Muhammad Kashif (3) · Neha Sharma, PhD (3) · Albert Leung, M.D. (2) · Ana-Maria Vranceanu, PhD (2) · Anar Murphy, PhD (2) · Claus Varnum, Prof., PhD, MD (2) · Colleen Fitzgerald, MD (2) · Daniel Pecos-Martin, PhD (2) · David Briskey, PhD (2) · Drew E Gonzalez, PhD (2)
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2025 (2), R34AT010364 (2), 1UG3AT013497-01 (1), 2004 (1), 2014 (1), 2016 (1), 2019 (1), 4UH3AR076731-02 (1), I21RX002741 (1), K01AG048259 (1), K23AR055664 (1), K23DE031807 (1), P30AG059297 (1), R01AG058702 (1), R01AR070474 (1)