48 recruiting. 48 Phase 1, 16 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 48 | Recruiting 48 |
| Phase 2 | 16 | Recruiting 16 |
Follow Pain: new trials by email Literature Review of Pain trials Research Report on Pain
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study of CYT-1010 in Healthy Volunteers and Participants With Acute Pain After Third Molar Extraction CYT-1010, Placebo - Acute Postoperative Pain, Dental Pain | Phase 1 / Phase 2 | Recruiting | Cytogel Pharma, LLC | 32 | 2026-09-25 | 2026-10-29 |
| Psilocybin to Treat Depression in Spinal Cord Injury Psilocybin (Usona Institute) - Spinal Cord Injury, Depression - Major Depressive Disorder | Phase 1 / Phase 2 | Recruiting | James J. Peters Veterans Affairs Medical Center | 30 | 2026-08-06 | 2026-08-10 |
| Two Different Therapeutic Interventions Applied During Blood Sampling in Children experimental group, experiment group, Control Group - Blood Sampling, Child, Only | Phase 1 | Recruiting | Igdir University | 105 | 2026-08-01 | 2026-09-09 |
| Single Ascending Doses (SAD) and Multiple Ascending Doses(MAD) Study of IG001119 in Healthy Adult Participants Placebo, IG001119 - Pain | Phase 1 | Recruiting | Iongen Therapeutics Co., Ltd. | 96 | 2026-07-07 | 2026-11-09 |
| A Study to Evaluate Ibuprofen (IBU) 62.5 mg and Acetaminophen (APAP) 125 mg/5 ml in an Oral Liquid Suspension Fixed-Dose Combination Product in Children Aged 6 to 11 Years Test Product - Pain | Phase 1 | Recruiting | HALEON | 12 | 2026-06-19 | 2026-06-30 |
| Adia Med of Winter Park LLC Lower Back Pain Research Study Umbilical Cord Blood-Derived Stem Cells and Exosomes, Placebo IV - Chronic Mechanical Lower Back Pain, Lower Back Pain | Phase 1 | Recruiting | Adia Med of Winter Park LLC | 100 | 2026-06-16 | 2026-06-17 |
| Intraperitoneal Irrigation of Ondansteron in Combination With Lidocaine in Acute Postoperative Pain ondansteron - Acue Postoperative Pain | Phase 1 / Phase 2 | Recruiting | Assiut University | 20 | 2026-06-01 | 2026-07-15 |
| Hormones, Outcomes, and Pain Pathways in Exercise Study Interventional Sports bra - Breast Pain, Mastalgia | Phase 1 | Recruiting | University of Houston | 140 | 2026-05-17 | 2026-06-02 |
| Simulation-Free Celiac Plexus Pain Ablation Using Stereotactic Body Radiotherapy (SBRT) in Participants With Cancer-Related Celiac Pain Simulation-free workflow, Celiac plexus SBRT - Pancreatic Cancer, Retroperitoneal Pain Syndrome | Phase 1 | Recruiting | Case Comprehensive Cancer Center | 5 | 2026-05-12 | 2026-09-22 |
| Novel Soluble Epoxide Hydrolase Inhibitor for Neuropathic Pain in Patients With Spinal Cord Injury EC5026 oral tablet, Placebo oral tablet - Spinal Cord Injuries, Neuropathic Pain | Phase 1 | Recruiting | EicOsis Human Health Inc. | 36 | 2026-05-01 | 2026-07-10 |
| Soy Tomato Juice to Improve Outcomes in Pancreatitis Soy-tomato juice product, Will include a soy-tomato juice product to be consumed during the 4 week intervention phase. A total of about 12 ounces (administered in two small cans) of the juice will be consumed - Recurrent Acute Pancreatitis, Chronic Pancreatitis | Phase 1 / Phase 2 | Recruiting | Ohio State University | 35 | 2026-04-02 | 2026-10-20 |
| Ketamine Assisted Psychotherapy for Treating Comorbid Chronic Pain and PTSD Ketamine Infusion, Mindfulness-based cognitive therapy - Chronic Pain, Posttraumatic Stress Disorder (PTSD) | Phase 1 / Phase 2 | Recruiting | Dr. Yuliya Knyahnytska | 30 | 2026-03-31 | 2026-09-15 |
| Study Evaluating the Safety, Efficacy and Pharmacokinetics of SYH9089 Injection in Patients Undergoing Abdominal Surgery. SYH9089 injection, Ropivacaine hydrochloride, 0.9 % sodium chloride - Postoperative Pain | Phase 1 | Recruiting | CSPC Ouyi Pharmaceutical Co., Ltd. | 60 | 2026-03-30 | 2026-07-15 |
| Safety and PK of Intrathecal CNTX-3001 for Intractable Chronic Low Back Pain CNTX-3001, Placebo - Lower Back Pain | Phase 1 | Recruiting | Centrexion Therapeutics | 16 | 2026-03-01 | 2026-03-23 |
| Sodium Aescinate for the Treatment of Low Back Pain (LBP) in Adults Sodium Aescinate Tablets, Placebo - Low Back Pain, Paraspinal Muscle | Phase 1 | Recruiting | Xijing Hospital | 40 | 2026-03-01 | 2026-03-20 |
| Optimizing Accelerated TMS for Chronic Pain With Thompson Sampling MagVenture X100 Pro transcranial magnetic stimulation system - Chronic Pain | Phase 1 | Recruiting | University of Minnesota | 30 | 2026-03-01 | 2026-03-27 |
| A Study Testing Topical Pain-Relieving Herbal Plasters in People Who Are Using Opioids for Their Pain Topical herbal plaster - Cancer Patients, Survivor Patients | Phase 1 | Recruiting | Memorial Sloan Kettering Cancer Center | 150 | 2026-02-23 | 2026-03-04 |
| Phase 1 Study of SBS-147 in Healthy Adults SBS-147, Placebo - Pain Acute, Pain | Phase 1 | Recruiting | Sparian Biosciences, Inc | 80 | 2026-01-08 | 2026-03-03 |
| Safety, Tolerability, and Pharmacokinetics of ASCT-83 in Healthy Adults ASCT-83, Placebo - Neuropathic Pain | Phase 1 | Recruiting | Alcamena Stem Cell Therapeutics | 72 | 2026-01-06 | 2026-06-16 |
| Prospective Randomized Controlled Clinical Study of Acupoint Application With Gutong Plaster in the Treatment of Moderate to Severe Cancer Pain On the basis of conventional analgesia, patients receive treatment with Gutong Plaster. - Cancer Pains | Phase 1 / Phase 2 | Recruiting | Cancer Institute and Hospital, Chinese Academy of Medical Sciences | 198 | 2025-12-25 | 2026-06-18 |
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Chronic Pain (7) · Pain, Postoperative (7) · Low Back Pain (5) · Agnosia (4) · Marijuana Abuse (4) · Neuralgia (4) · Abdominal Pain (3) · Acute Pain (3) · Back Pain (3) · Cancer Pain (3) · Inflammation (2) · Motor Activity (2) · Neoplasms (2) · Osteoarthritis (2)
Neurologic Manifestations (48) · Pathological Conditions, Signs and Symptoms (48) · Signs and Symptoms (48) · Nervous System Diseases (12) · Pathologic Processes (11) · Mental Disorders (6) · Neuromuscular Diseases (6) · Peripheral Nervous System Diseases (6) · Postoperative Complications (6) · Behavior (5) · Musculoskeletal Diseases (5) · Back Pain (4) · Chemically-Induced Disorders (4) · Digestive System Diseases (4)
Dronabinol (4) · Ketamine (3) · Sodium Chloride (3) · nabiximols (3) · Cannabidiol (2) · Transcranial Magnetic Stimulation (2) · 6-hydroxynorketamine (1) · Adrenal Cortex Hormones (1) · Analgesia, Epidural (1) · Antibodies (1) · Arginine Vasopressin (1) · Bupivacaine (1) · Control Groups (1) · Cyclophosphamide (1) · Diclofenac (1)
University of California, Los Angeles (3) · Adia Med of Winter Park LLC (1) · Alcamena Stem Cell Therapeutics (1) · Alimorad Farshchian (1) · Assiut University (1) · CSPC Ouyi Pharmaceutical Co., Ltd. (1) · Cancer Institute and Hospital, Chinese Academy of Medical Sciences (1) · Case Comprehensive Cancer Center (1) · Centrexion Therapeutics (1) · Consano Bio (1) · Cytogel Pharma, LLC (1) · Dr. Yuliya Knyahnytska (1) · EicOsis Human Health Inc. (1) · HALEON (1) · Icahn School of Medicine at Mount Sinai (1)
United States (36) · China (4) · Australia (3) · Canada (1) · Croatia (1) · Egypt (1) · France (1) · New Zealand (1) · Pakistan (1) · Turkey (Türkiye) (1)
Ziva Cooper, PhD (2) · Alexander B Herman, MD, PhD (1) · Alimorad Farshchian, MD (1) · Asokumar Buvanendran, MD (1) · Brett Johnson, MD (1) · Brian Louie, M.D. (1) · David Darrow (1) · Edmund Nesti, PhD (1) · Evan Thomas, MD, PhD (1) · Fadel Zeidan, PhD (1) · Grace Lim, MD, MSc (1) · Guoping Yang, PhD (1) · Guy Ludbrook, MD (1) · Hongjun N Wang, PhD (1)
PMID 10360702, PMID 10488513, PMID 11172169, PMID 12709856, PMID 16227895, PMID 17256032, PMID 35921598, PMID 40615143
1UG3NS123965-01 (1), I01CX002516 (1), R01AR084021 (1), R01DA057252 (1), R01DA058620 (1), R01DK138871 (1), R01MH134538 (1), R44NS145934 (1)