189 completed, 75 unknown, 39 recruiting, 16 active not recruiting. 225 Not applicable, 18 Phase 3, 16 Phase 2, 9 Phase 4, 4 Phase 1.
Follow Pain, Chronic: new trials by email Literature Review of Pain, Chronic trials Research Report on Pain, Chronic
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Mantram Repetition Versus Health Education for Veterans With PTSD and Chronic Pain Mantram Repetition Program for PTSD + Pain, Health Education while Living with Pain - Stress Disorders, Post-Traumatic, Pain, Chronic | Not applicable | Not yet recruiting | VA Office of Research and Development | 170 | 2027-04-01 | 2026-07-27 |
| Efficacy and Safety of Canadá Association in the Treatment of Chronic Pain Canadá, Canadá placebo, Dipyrone - Pain, Chronic | Phase 2 | Withdrawn | EMS | 2026-09-01 | 2023-09-08 | |
| RUTISS-Diary and RUTISS-65 Study Non-interventional Patient Reported Outcome Measure Development (RUTISS-Diary), Non-interventional Patient Reported Outcome Measure Development (RUTISS-65) - Urology, Urological Diseases | Not yet recruiting | Katherine Finlay | 200 | 2026-07-08 | 2026-07-13 | |
| Butyrate and Taurine for Chronic Postsurgical Pain in Adult Cardiac Surgical Patients Butyrate and Taurine, Placebo - Pain, Acute, Pain, Chronic | Not applicable | Recruiting | Chinese University of Hong Kong | 216 | 2026-06-20 | 2026-10-22 |
| Pain-at-Work Toolkit (Definitive Trial) The Pain-at-Work Toolkit is an web-based digital resource, providing education and information about behaviour change related to the self-management of chronic pain in the workplace., Control (Standard treatment) - Chronic Pain, Pain, Chronic | Not applicable | Enrolling by invitation | University of Nottingham | 685 | 2026-05-11 | 2026-09-04 |
| Person-Centred AI Support in Interdisciplinary Rehabilitation for Chronic Pain Interdisciplinary treatment (IDT) + Clinical Decision Support System (CDSS), Interdisciplinary treatment (IDT) - Pain, Chronic, Chronic Pain, Widespread | Not applicable | Not yet recruiting | Bjorn Ang | 400 | 2026-05-01 | 2025-07-23 |
| Ultrasound Guided Pecs Block and Ketamine Infusion for Preventing Chronic Pain in Patients Undergoing Breast Cancer Surgery Ketamine, Pecs block, Nalbuphine - Breast Cancer, Pain, Chronic | Not applicable | Not yet recruiting | Aga Khan University | 120 | 2026-03-16 | 2026-02-19 |
| Interoceptive Awareness and Function in Adolescents With Chronic Pain Occupational Therapy - Chronic Pain, Chronic Pain Syndrome | Recruiting | Connecticut Children's Medical Center | 49 | 2026-02-25 | 2026-04-27 | |
| Home-based Transcutaneous Auricular Vagus Nerve Stimulation (taVNS) for IBS Pain Home-based taVNS intervention - Pain, Chronic, Irritable Bowel Syndrome | Not applicable | Recruiting | Yale University | 80 | 2026-01-19 | 2026-04-13 |
| Analgesic Efficacy and Safety of Topical VMD-3866 Gel in Management of Pain Induced by Chemotherapy (CIPN) VMD-3866 Gel, Placebo Gel - Chemotherapy-induced Peripheral Neuropathy, Chemotherapy-induced Neuropathic Pain | Phase 2 | Recruiting | VM Therapeutics LLC | 16 | 2025-12-12 | 2026-10-21 |
| Effectiveness of the Sana Device on Fibromyalgia Symptoms Sana Device, Sana Device (Control) - Fibromyalgia, Pain, Chronic | Not applicable | Withdrawn | Sana Health | 2025-12-01 | 2026-04-24 | |
| Pain Reprocessing Therapy in Post-Operative Knee Pain Pain reprocessing therapy (PRT), Usual care - Pain, Chronic, Knee Pain Chronic | Phase 2 | Recruiting | Weill Medical College of Cornell University | 110 | 2025-08-13 | 2026-08-05 |
| Developing a Nonpharmacological Pain Intervention for Community-dwelling Older Adults With Dementia Tailored Physical Activity Program - Pain, Chronic, Dementia, Mild | Not applicable | Not yet recruiting | Drexel University | 40 | 2025-06-02 | 2025-03-11 |
| The PROACTIVE Study for Black Elders PROACTIVE Intervention - Musculoskeletal Pain, Chronic Pain | Not applicable | Recruiting | University of Florida | 120 | 2025-05-07 | 2026-06-04 |
| Methadone Dose Monitoring With a Remote Medication Monitor Measurement of Methadone in the Interstitial Fluid (ISF) before and after prescribed dose taken ex vivo, Measurement of Methadone in the Interstitial Fluid before and after prescribed dose taken in vivo, ISF Extraction Device 2 - Methadone Toxicity, Methadone Overdose | Not yet recruiting | Cari Health Inc. | 30 | 2025-04-26 | 2025-02-20 | |
| Prescription Opioids, Brain Structure, and Cognition in Older Adults With Chronic Pain Opioid, Opioid Placebo - Pain, Chronic | Phase 2 | Recruiting | Mayo Clinic | 200 | 2025-04-16 | 2026-01-08 |
| Prospective Validation Study of an E-health Tool for Patient Selection for SCS Pain, Chronic | Not yet recruiting | Erasmus Medical Center | 100 | 2025-03-01 | 2025-03-03 | |
| Cognitive Behavioral Therapy for Chronic Pain in Adults With Cerebral Palsy Cognitive Behavioral Therapy for Chronic Pain - Cerebral Palsy, Pain, Chronic | Not applicable | Active not recruiting | Hugo W. Moser Research Institute at Kennedy Krieger, Inc. | 14 | 2025-02-27 | 2026-04-27 |
| Physical Activity and Percussive Massage Therapy for Reducing Pain in Older Women Self-monitoring, Physical activity and percussive massage therapy education, Percussive massage therapy - Pain, Chronic | Not applicable | Completed | University of Michigan | 108 | 2025-01-15 | 2025-11-10 |
| Effect of Mirror Therapy on the Arteriovenous Fistula Cannulation-related Pain and Anxiety Mirror Therapy - Pain, Chronic, Fistula | Not applicable | Completed | Istanbul University | 54 | 2025-01-05 | 2025-05-09 |
Showing 20 of 354. Sign in to see all of them.
Chronic Pain (354) · Pain (74) · Acute Pain (51) · Pain, Postoperative (41) · Agnosia (38) · Neuralgia (23) · Back Pain (22) · Breast Neoplasms (17) · Somatoform Disorders (17) · Anxiety Disorders (15) · Low Back Pain (14) · Osteoarthritis, Knee (12) · Depression (11) · Opioid-Related Disorders (11) · Pain, Intractable (11)
Pathological Conditions, Signs and Symptoms (354) · Neurologic Manifestations (353) · Signs and Symptoms (353) · Pain (280) · Nervous System Diseases (99) · Pathologic Processes (68) · Mental Disorders (61) · Musculoskeletal Diseases (54) · Postoperative Complications (49) · Neuromuscular Diseases (47) · Neurobehavioral Manifestations (42) · Perceptual Disorders (41) · Peripheral Nervous System Diseases (31) · Behavior (29) · Joint Diseases (27)
Surveys and Questionnaires (9) · Exercise (7) · Anesthetics, Local (6) · Cognitive Behavioral Therapy (6) · Ketamine (5) · Acetaminophen (4) · Dexmedetomidine (4) · Methadone (4) · Morphine (4) · Therapeutics (4) · Ultrasonography (4) · Control Groups (3) · Educational Status (3) · Saline Solution (3) · Analgesia, Epidural (2)
Assiut University (9) · Keimyung University Dongsan Medical Center (9) · Apurano Pharmaceuticals GmbH (8) · Aretaieion University Hospital (8) · Weill Medical College of Cornell University (7) · Teesside University (6) · Diskapi Teaching and Research Hospital (4) · Hacettepe University (4) · Mahidol University (4) · Northwestern University (4) · University of Michigan (4) · University of Washington (4) · Başakşehir Çam & Sakura City Hospital (3) · Johns Hopkins University (3) · Mansoura University (3)
United States (112) · Turkey (Türkiye) (39) · United Kingdom (18) · Egypt (17) · Canada (16) · Germany (12) · Greece (12) · South Korea (12) · Spain (11) · Belgium (9) · France (9) · Sweden (9) · Italy (8) · Taiwan (8) · Denmark (6)
Kassiani Theodoraki, PhD, DESA (5) · Holly Blake, PhD (3) · Ji H Hong, Ph.D (3) · Kassiani Theodoraki (3) · Burak Erken, MD (2) · Cary Reid, MD, PhD (2) · Charmaine Semenluk, MD (2) · Jean Tang, PhD (2) · Jennifer Stinson, RN, PhD (2) · Ji H Hong (2) · John Peabody, MD, PhD (2) · Mirit Argov (2) · Natalie Bloom Lyons, M.S. (2) · Susanne Becker, PD Dr. (2) · Tarek M. Shams, MD (2)
PMID 30908578, PMID 10618804, PMID 11586161, PMID 14715402, PMID 15615926, PMID 15896276, PMID 16303817, PMID 16427357, PMID 16558352, PMID 18211593, PMID 19007576, PMID 19011263, PMID 19260241, PMID 19903919, PMID 19910457, PMID 20479531, PMID 20650691, PMID 2095010, PMID 21352516, PMID 21565446, PMID 21872812, PMID 21912311, PMID 22150651, PMID 22506152, PMID 23370085, PMID 23386031, PMID 23538392, PMID 23743101, PMID 23877110, PMID 23942592, PMID 23973143, PMID 24118428, PMID 24921074, PMID 24989067, PMID 25257144, PMID 25313534, PMID 25506545, PMID 25831199, PMID 25931250, PMID 26031689, PMID 26033064, PMID 26294268, PMID 26468991, PMID 26509683, PMID 26559319, PMID 26818413, PMID 27885426, PMID 27887616, PMID 27922948, PMID 28214943
P30AG022845 (3), 1UF1MH121949-01 (1), 1UG3AT009767-01 (1), 2016 (1), 2017 (1), 2019 (1), 2023 (1), 2025 (1), 3UG1DA015831-24S1 (1), 4UF1MH121949 (1), 4UH3AT009767-03 (1), I01RD001563 (1), K01AG048259 (1), K23AG081547 (1), K23AR081409 (1)