15 unknown, 13 completed, 13 recruiting, 4 active not recruiting. 29 Not applicable, 4 Phase 2, 3 Phase 4, 2 Early Phase 1, 2 Phase 1.
Follow OCD: new trials by email Literature Review of OCD trials Research Report on OCD
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Locating Biomarkers in OCD Through Behavioral Tasks Beads Task, PROVOC Tasks - OCD, Obsessive-Compulsive Disorder | Not yet recruiting | Baylor College of Medicine | 20 | 2027-03-01 | 2026-06-30 | |
| Digital Coach to Support Exposure Therapy Homework for Anxious Youth BraveBot, Self-Guided Exposure Therapy Homework - Anxiety Disorders, OCD | Not applicable | Not yet recruiting | Massachusetts General Hospital | 50 | 2027-02-01 | 2026-10-07 |
| Testing Delivery Modalities of Team-Based CBT for Pediatric Anxiety in Community Health Settings. Team-delivered, exposure-based CBT - Obsessive Compulsive Disorder (OCD), Pediatric Anxiety Disorders | Not applicable | Recruiting | Bradley Hospital | 501 | 2025-11-01 | 2026-07-31 |
| Effect of Emotion-Focused Acceptance and Commitment Therapy on Obsessive-Compulsive Disorder Symptom Severity Emotion-Focused Acceptance and Commitment Therapy (ACT) Group Psychotherapy - OCD, Obsessive - Compulsive Disorder | Not applicable | Recruiting | Mehmet Emrah Karadere | 36 | 2025-10-01 | 2026-06-03 |
| Safety and Feasibility of FUS Next Generation Dome Helmet (NGDH) to Perform Neuromodulation in Patients With Treatment Refractory Obsessive Compulsive Disorder (OCD) Next Generation Dome Helmet (NGDH) - OCD, Obsessive-Compulsive Disorder (OCD) | Not applicable | Recruiting | Sunnybrook Health Sciences Centre | 20 | 2025-09-23 | 2026-07-15 |
| Retrospective Analyses of the Greenbrook Database Evaluating Mental Health Treatments Patients treated with NeuroStar TMS, Patients treated with Esketamine - Depression, OCD | Recruiting | Neuronetics | 12000 | 2025-05-15 | 2026-04-09 | |
| Light Therapy for Obsessive-compulsive Disorder (OCD) Light therapy - OCD | Early Phase 1 | Recruiting | Washington University School of Medicine | 40 | 2024-12-16 | 2026-08-18 |
| Computer Game, Qualitative, and MEG/EEG Assessment of Serotonergic Psychedelics Serotonergic Psychedelic, Placebo - OCD, Major Depressive Disorder (MDD) | Terminated | Yale University | 5 | 2024-12-12 | 2026-07-09 | |
| Open-Label Psilocybin Study in Transdiagnostic Population Psilocybin - Transdiagnostic, Depression - Major Depressive Disorder | Phase 1 | Recruiting | Yale University | 50 | 2024-10-17 | 2026-03-11 |
| Testing a Transdiagnostic TMS Treatment Target transcranial magnetic stimulation - Major Depressive Disorder, Depression | Early Phase 1 | Completed | Brigham and Women's Hospital | 10 | 2024-09-09 | 2026-07-13 |
| Neuromodulation for a Novel OCD Biomarker and Treatment high definition transcranial alternating current stimulation - OCD | Not applicable | Recruiting | Boston University Charles River Campus | 90 | 2024-07-01 | 2026-07-23 |
| Behavioural Development, Long-term Outcomes and Opportunities to Optimize Youth Mental Health Trajectories Depression - Major Depressive Disorder, Bipolar | Recruiting | Douglas Mental Health University Institute | 560 | 2024-07-01 | 2025-05-18 | |
| Discovering Factors in the Clinical Study Journey of Patients With OCD OCD, Obsessive-Compulsive Disorder | Unknown | Power Life Sciences Inc. | 500 | 2024-06-01 | 2023-05-31 | |
| Personalized DBS for OCD Guided by Stereoencephalography Mapping Deep Brain Stimulation - Obsessive-Compulsive Disorder, OCD | Not applicable | Active not recruiting | Andrew Moses Lee, MD, PhD | 10 | 2024-05-24 | 2026-06-05 |
| Multi-session, Personalized Cognitive Bias Modification for Thought-Action-Fusion CBM-TAF, CBM-SMP - OCD | Not applicable | Completed | Han Joo Lee | 83 | 2024-04-18 | 2026-07-15 |
| Objective Characterizatoion of Repetitive Behaviors EEG, MRI - OCD, Tic Disorders | Not applicable | Recruiting | Institut National de la Santé Et de la Recherche Médicale, France | 50 | 2023-12-28 | 2026-02-12 |
| pBFS Guided High-dose rTMS Therapy for Treatment-Resistant Obsessive-Compulsive Disorder active rTMS treatment, sham rTMS treatment - Obsessive-Compulsive Disorder, OCD | Not applicable | Unknown | Changping Laboratory | 30 | 2023-07-20 | 2023-07-27 |
| pBFS Guided rTMS Therapy for Treatment-resistant Obsessive-Compulsive Disorder active rTMS treatment, sham rTMS treatment - Obsessive-Compulsive Disorder, OCD | Not applicable | Unknown | Changping Laboratory | 30 | 2023-07-16 | 2023-07-27 |
| Cerebral and Cognitive Markers of Treatment Resistance in Obsessive Compulsive Disorder Functional MRI - OCD | Recruiting | Centre Hospitalier Henri Laborit | 100 | 2023-07-03 | 2026-01-13 | |
| Does TMS Affect Neuroplasticity? The Role of Brain-derived Neurotrophic Factor and Neuronal Cell Adhesion Molecules - an Intensive Clinical Protocol Among Patients With Obsessive-compulsive Disorders continuous theta burst stimulation - cTBS - OCD | Phase 4 | Completed | Wroclaw Medical University | 40 | 2023-07-01 | 2024-01-30 |
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Obsessive-Compulsive Disorder (15) · Anxiety Disorders (7) · Stress Disorders, Post-Traumatic (6) · Depression (5) · Compulsive Personality Disorder (3) · Depressive Disorder, Major (3) · Phobia, Social (3) · Agoraphobia (2) · Anxiety, Separation (2) · Attention Deficit Disorder with Hyperactivity (2) · Behavior, Addictive (2) · Borderline Personality Disorder (2) · Feeding and Eating Disorders (2) · Generalized Anxiety Disorder (2) · Mood Disorders (2)
Mental Disorders (24) · Anxiety Disorders (12) · Behavior (8) · Trauma and Stressor Related Disorders (7) · Pathological Conditions, Signs and Symptoms (6) · Stress Disorders, Traumatic (6) · Behavioral Symptoms (5) · Nervous System Diseases (5) · Neurodevelopmental Disorders (5) · Signs and Symptoms (5) · Personality Disorders (4) · Brain Diseases (3) · Central Nervous System Diseases (3) · Chemically-Induced Disorders (3) · Depressive Disorder (3)
Sertraline (3) · Deep Brain Stimulation (2) · Duloxetine Hydrochloride (2) · Escitalopram (2) · Transcranial Magnetic Stimulation (2) · Acetylcysteine (1) · Aripiprazole (1) · Ascorbic Acid (1) · Cognitive Behavioral Therapy (1) · Cognitive Restructuring (1) · Drug Therapy (1) · Electroencephalography (1) · Esketamine (1) · Fluvoxamine (1) · Implosive Therapy (1)
Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh (3) · Baylor College of Medicine (3) · Yale University (3) · Bradley Hospital (2) · Changping Laboratory (2) · Duke University (2) · Stanford University (2) · University of Minnesota (2) · Andrew Moses Lee, MD, PhD (1) · BeerYaakov Mental Health Center (1) · Beersheva Mental Health Center (1) · Boston University Charles River Campus (1) · Brigham and Women's Hospital (1) · Centre Hospitalier Henri Laborit (1) · Douglas Mental Health University Institute (1)
United States (27) · China (4) · Bangladesh (3) · Israel (3) · Brazil (2) · Canada (2) · France (2) · Malaysia (1) · Poland (1) · Portugal (1) · South Korea (1) · Turkey (Türkiye) (1) · United Kingdom (1)
Carolyn Rodriguez, MD, PhD (2) · Gail A Bernstein, MD (2) · Hesheng Liu, Ph.D. (2) · Wayne Goodman, MD (2) · A Moses Lee, MD, PhD (1) · Albert R Powers, MD, PhD (1) · Andrada D Neacsiu, PhD (1) · Andrew Krystal, MD (1) · Benjamin Kelmendi, MD (1) · Beyza Baran Boz (1) · Christopher J Pittenger, MD, Ph.D. (1) · Conor Liston, MD, PhD (1) · Doron Todder, MD (1)
PMID 26214725, PMID 26674413, PMID 27830935, PMID 30768407, PMID 31780963, PMID 33631349
R01MH121597 (1), R01MH129302 (1), R21MH101395 (1), R34MH083115 (1), UG3MH137656 (1)