Drug Therapy: Clinical Trials

1,394 trials of Drug Therapy, newest first

ClinicalTrials Daily  ·  Areas  ·  Conditions  ·  Drugs  ·  Sponsors  ·  

393 completed, 329 unknown, 310 recruiting, 142 not yet recruiting. 678 Phase 2, 264 Phase 3, 183 Not applicable, 180 Phase 1, 46 Phase 4.

By phase and status

PhaseTrialsStatus
Phase 2678Unknown 170, Recruiting 167, Completed 142, Not yet recruiting 84, Terminated 45, Active not recruiting 36, Withdrawn 29, Suspended 4, Enrolling by invitation 1
Phase 3264Completed 90, Recruiting 55, Unknown 55, Not yet recruiting 22, Active not recruiting 17, Terminated 17, Withdrawn 7, Suspended 1
Not applicable183Completed 66, Unknown 44, Recruiting 39, Not yet recruiting 15, Active not recruiting 10, Terminated 4, Withdrawn 4, Enrolling by invitation 1
Phase 1180Completed 52, Recruiting 45, Unknown 31, Not yet recruiting 19, Terminated 13, Active not recruiting 11, Withdrawn 6, Suspended 3
Phase 446Unknown 19, Completed 15, Active not recruiting 2, Enrolling by invitation 2, Not yet recruiting 2, Recruiting 2, Terminated 2, Withdrawn 2
Early Phase 110Recruiting 3, Completed 2, Not yet recruiting 2, Active not recruiting 1, Terminated 1, Unknown 1

Follow Drug Therapy: new trials by email Literature Review of Drug Therapy trials Research Report on Drug Therapy

Trials newest first · largest first

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

TrialPhaseStatusSponsorEnrollmentStartUpdated
Shuganhuazhuo Formula for Advanced Hepatocellular Carcinoma With Damp-Heat Syndrome
Shuganhuazhuo Formula, Targeted therapy, Immunotherapy - HCC - Hepatocellular Carcinoma, Chinese Herbal Medicine
Phase 2Not yet recruitingXiang-Qian1202027-09-012026-08-27
Cannabis Gummy for the Improvement of Sleep and Quality of Life in Patients With Cancer, Pillow Trial
Actigraphy, Best Practice, Biospecimen Collection - Hematopoietic and Lymphatic System Neoplasm, Malignant Solid Neoplasm
Phase 1 / Phase 2Not yet recruitingTheodore Brasky PhD502027-01-152026-10-14
BSB-2002 After Cyclophosphamide and Fludarabine for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia Patients With NPM1 Mutation
Biospecimen Collection, Bone Marrow Aspiration, Bone Marrow Biopsy - Recurrent Acute Myeloid Leukemia, Refractory Acute Myeloid Leukemia
Phase 1Not yet recruitingCity of Hope Medical Center192026-12-142026-05-13
Evaluating the Addition of Maintenance Immunotherapy Compared to the Usual Treatment of Chemotherapy and Autologous Stem Cell Transplant Alone for High-risk Patients With Relapsed or Refractory Hodgkin Lymphoma
3-Dimensional Conformal Radiation Therapy, Autologous Hematopoietic Stem Cell Transplantation, Biospecimen Collection - Recurrent Classic Hodgkin Lymphoma, Refractory Classic Hodgkin Lymphoma
Phase 2 / Phase 3Not yet recruitingNational Cancer Institute (NCI)3742026-12-042026-07-08
Laser Interstitial Thermal Therapy (LiTT) With Cemiplimab or Other Chemotherapy in Recurrent Glioblastomas
NeuroBlate® Laser Ablation Laser Interstitial Thermal Therapy, Cemiplimab, Chemotherapy - Glioblastoma, Glioblastoma, IDH-wildtype
Phase 2Not yet recruitingWashington University School of Medicine992026-11-302026-10-20
A Phase I Study of HS-20093 Injection in Combination Therapy in Non-Small Cell Lung Cancer
HS-20093, Ivonescimab, Chemotherapy - Non-Small Cell Lung Cancer
Phase 1Not yet recruitingHansoh BioMedical R&D Company1022026-11-102026-10-27
SPGL008 in Combination With SSGJ-706 ± Chemotherapy for Advanced Non-small Cell Lung Cancer
SSGJ-706, SPGL008, Chemotherapy - Non Small Cell Lung Cancer
Phase 2Not yet recruitingShenyang Sunshine Pharmaceutical Co., LTD.2202026-11-012026-10-15
Fecal Microbiota Transplantation Combined With NALIRIFOX Plus Serplulimab as First-line Treatment for Advanced or Metastatic Pancreatic Ductal Adenocarcinoma.
FMT combined with chemotherapy plus immunotherapy, Chemotherapy+Immunotherapy - Locally Advanced Pancreatic Ductal Adenocarcinoma, Metastatic Pancreatic Ductal Adenocarcinoma (PDAC)
Phase 2Not yet recruitingTianjin Medical University Cancer Institute and Hospital402026-11-012026-10-02
Off-Label Treatment With Immune Checkpoint Inhibitor Blockade
One or more off-label ICIs alone or with other on-label ICI(s), Off-label ICI(s) with targeted therapy, off-label ICI(s) with other agents that are not targeted (including, but not limited to, chemotherapy, hormonal therapy, immunotherapy other than ICIs) with or without targeted agents - Malignancy
Phase 2Not yet recruitingMedical College of Wisconsin2312026-11-012026-08-10
Optimizing Response to Immunotherapy With Online Adaptive Pulsed Radiotherapy in Incurable Head and Neck Cancers
Pulsed Adaptive Radiotherapy Combined with Pembrolizumab with or without chemotherapy - Head and Neck Squamous Cell Carcinoma (HNSCC)
Phase 2Not yet recruitingUniversity Health Network, Toronto482026-11-012026-10-22
Efficacy and Safety of Ivonescimab Plus Pemetrexed and Platinum-Based Chemotherapy in Advanced Malignant Pleural Mesothelioma
Ivonescimab Combined With Chemotherapy - Malignant Pleural Mesothelioma, Advanced
Phase 1 / Phase 2RecruitingRuijin Hospital782026-11-012026-10-26
IL-18 Armored STEAP1 CAR T Cells for the Treatment of Metastatic Castration Resistant Prostate Cancer
FH-STEAP1 IL-18 CAR T cells, Antiandrogen Therapy, Biospecimen Collection - Metastatic Castration-Resistant Prostate Adenocarcinoma, Stage IVB Prostate Cancer AJCC v8
Phase 1Not yet recruitingFred Hutchinson Cancer Center202026-10-312026-09-04
Safety and Efficacy of Radiotherapy Combined With Immunochemotherapy in Pre-treated SCLC Patients With Liver Metastases
Immunotherapy, Chemotherapy (Etoposide, Nab-paclitaxel, Irinotecan, or Lurbinectedin), low-dose radiation - Lung Cancer (SCLC)
Phase 2Not yet recruitingSichuan University302026-10-312026-05-05
A Study of Perioperative Adebrelimab Plus Chemotherapy Versus Adjuvant Therapy in Patients With Resectable NSCLC
Adebrelimab (SHR-1316) + chemotherapy, Adebrelimab - Non-small Cell Lung Cancer (NSCLC)
Phase 3Not yet recruitingWest China Hospital10882026-10-312026-10-26
Primary Radiotherapy In MEtastatic Lung Cancer
Radiotherapy followed by chemotherapy, Standard of Care (SOC) - Carcinoma, Non-Small-Cell Lung (NSCLC)
Phase 3RecruitingTrans Tasman Radiation Oncology Group4202026-10-302026-10-23
Addition of Platinum-based Chemotherapy to Tislelizumab in PD-L1high Metastatic Non-small Cell Lung Cancer With a High Tumor Burden
Tislelizumab, Tislelizumab Combined With Chemotherapy, Pembrolizumab - Non-small Cell Lung Cancer Metastatic
Phase 3Not yet recruitingAIO-Studien-gGmbH2302026-10-302026-10-26
Chemotherapy Combined With or Without Short-Course Radiotherapy Versus Chemotherapy Alone as Neoadjuvant Therapy for High-Risk Locally Advanced Colon Cancer With pMMR/MSS
short-course radiotherapy, Serplulimab, CapOx(Capecitabine+ Oxaliplatin) - Locally Advanced Colon Cancer, pMMR
Phase 3Not yet recruitingFudan University4802026-10-152026-10-16
A Study of Targeted Post-Surgery Radiation Therapy for Non-Small Cell Lung Cancer With Remaining Lymph Node Cancer After Treatment
Chemotherapy, Immunotherapy, Intensity-Modulated Radiation Therapy - Lung Non-Small Cell Carcinoma
Phase 2RecruitingAlliance for Clinical Trials in Oncology1642026-10-142026-10-19
Pharmacogenomics ANDA SNP Clinical Study - Topotecan and Single Nucleotide Polymorphisms
Topotecan - usual, Topotecan - study - SCLC
Phase 2 / Phase 3Active not recruitingHan Xu, M.D., Ph.D., FAPCR, Medical Director, IRB Chair6002026-10-052026-10-08
THC Versus THC/CBD Versus Placebo to Improve Sleep Quality for Patients With Solid Organ Cancer and Insomnia
Biospecimen Collection, Placebo Administration, Single Agent Therapy - Insomnia, Malignant Solid Neoplasm
Phase 2Not yet recruitingMayo Clinic692026-10-012026-09-02

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Conditions studied

Carcinoma, Non-Small-Cell Lung (167)  ·  Breast Neoplasms (112)  ·  Colorectal Neoplasms (77)  ·  Neoplasms (65)  ·  Lung Neoplasms (61)  ·  Pancreatic Neoplasms (57)  ·  Neoplasm Metastasis (52)  ·  Stomach Neoplasms (52)  ·  Ovarian Neoplasms (45)  ·  Rectal Neoplasms (44)  ·  Esophageal Neoplasms (40)  ·  Esophageal Squamous Cell Carcinoma (40)  ·  Squamous Cell Carcinoma of Head and Neck (36)  ·  Head and Neck Neoplasms (35)  ·  Leukemia, Myeloid, Acute (32)

Sponsors

Fudan University (43)  ·  Sun Yat-sen University (35)  ·  Tianjin Medical University Cancer Institute and Hospital (21)  ·  Hoffmann-La Roche (18)  ·  Peking Union Medical College Hospital (18)  ·  M.D. Anderson Cancer Center (16)  ·  National Cancer Institute (NCI) (14)  ·  Ruijin Hospital (13)  ·  Zhejiang Cancer Hospital (13)  ·  Cancer Institute and Hospital, Chinese Academy of Medical Sciences (12)  ·  Sichuan University (12)  ·  Pfizer (11)  ·  Second Affiliated Hospital, Zhejiang University, School of Medicine (10)  ·  Shanghai Chest Hospital (10)  ·  Mayo Clinic (9)

Countries

China (529)  ·  United States (355)  ·  France (109)  ·  Italy (94)  ·  Germany (75)  ·  Spain (75)  ·  Canada (55)  ·  United Kingdom (51)  ·  South Korea (49)  ·  Belgium (47)  ·  Netherlands (46)  ·  Australia (42)  ·  Taiwan (34)  ·  Switzerland (33)  ·  Poland (32)

Top investigators

You Lu, MD (4)  ·  Birendra K Sah, PH D (3)  ·  Chen Li, PH D (3)  ·  Hongmeng Yu, MD,PHD (3)  ·  Paul Schwarzenberger, MD (3)  ·  Tao Ouyang, MD (3)  ·  Yongchang Zhang, MD (3)  ·  Zhenggang Zhu, PH D (3)

Results publications

PMID 40812353, PMID 26808342, PMID 28596308, PMID 30062662, PMID 35143424, PMID 37185961, PMID 37280366, PMID 38572751, PMID 39368878, PMID 40288679, PMID 40467307, PMID 10332020, PMID 10473315, PMID 10581077, PMID 10655437, PMID 10660394, PMID 10742367, PMID 10813118, PMID 10870204, PMID 10996924, PMID 11171826, PMID 11188984, PMID 11208820, PMID 11254763, PMID 11299481, PMID 11556297, PMID 11560968, PMID 11675328, PMID 11870157, PMID 11937316, PMID 11971127, PMID 12177103, PMID 12434281, PMID 12436398, PMID 12525193, PMID 1418457, PMID 14506149, PMID 14645425, PMID 14645636, PMID 15128893, PMID 15131031, PMID 15151953, PMID 15383798, PMID 15496622, PMID 15534360, PMID 15812833, PMID 15816939, PMID 15928658, PMID 15936546, PMID 15939524

NIH funding

2017 (11), 2023 (11), 2016 (9), 2025 (7), U10CA180820 (5), 2018 (4), 2009 (3), 2014 (3), 2015 (3), P30CA015704 (3), P30CA016672 (3), P30CA033572 (3), U10CA031946 (3), 2005 (2), P30CA006973 (2)