3506 completed. 3506 Phase 3, 512 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 3506 | Completed 3506 |
| Phase 2 | 512 | Completed 512 |
Follow Nervous System Diseases: new trials by email Literature Review of Nervous System Diseases trials Research Report on Nervous System Diseases
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Intranasal Insulin to Prevent Intensive Care Unit Delirium Intranasal insulin-40U, Intranasal sodium chloride 0.9% - Delirium - Postoperative | Phase 2 / Phase 3 | Completed | Radboud University Medical Center | 30 | 2026-04-30 | 2026-08-03 |
| Heparin for RAO Post-Transradial Angiography in AIS Heparin - Therapeutic dosage, Saline (0.9% NaCl) - Acute Ischemic Stroke | Phase 3 | Completed | Xiang Luo | 440 | 2025-08-04 | 2026-03-24 |
| Virtual Reality for Pain and Anxiety Relief During Peripheral Angioplasty Virtual Reality, dexketoprofen + midazolam - Peripheral Angioplasty, Pain Management | Phase 2 / Phase 3 | Completed | Kastamonu University | 52 | 2025-08-01 | 2025-11-19 |
| A Phase 3 Study to Assess the Immune Response And Safety Of Rmenb+Omv Nz In Primed Healthy Participants (10 To 20 Years Old) rMenB+OMV NZ vaccine - Meningitis | Phase 3 | Completed | GlaxoSmithKline | 312 | 2025-07-07 | 2026-04-21 |
| Ultrasound-Guided Stellate Ganglion Block in Fibromyalgia Lidocaine and Dexamethasone, Normal Saline - Fibromyalgia | Phase 2 / Phase 3 | Completed | Sanliurfa Education and Research Hospital | 68 | 2025-06-01 | 2026-01-16 |
| A Clinical Trial of Local Infiltration With Injection CZ1S for Postoperative Analgesia After Hemorrhoidectomy CZ1S for injection, ropivacaine, Normal Saline (0.9% NaCl) - Hemorrhoids Second Degree, Hemorrhoids Third Degree | Phase 3 | Completed | Zhejiang Cuize Pharmaceutical Technology Co., Ltd. | 243 | 2025-05-21 | 2026-11-02 |
| Safety and Efficacy Study of YZJ-1139 Tablets in Insomnia Disorder YZJ-1139, Zolpidem - Insomnia Disorder | Phase 3 | Completed | Shanghai Haiyan Pharmaceutical Technology Co., Ltd. | 61 | 2025-03-25 | 2026-06-29 |
| Dexmedetomidine in Reducing Postoperative Delirium in Cardiac Surgery Patients Dexmedetomidine nasal spray - Postoperative Delirium, Preoperative Sleep Disorder | Phase 3 | Completed | Xijing Hospital | 686 | 2025-03-03 | 2026-09-11 |
| Effect of Maolactin™ FMR on Exercise Recovery, Inflammation and Muscle Comfort in an Otherwise Healthy Population Maolactin, Maltodextrin - Chronic Inflammation, Mobility | Phase 3 | Completed | RDC Clinical Pty Ltd | 97 | 2025-02-27 | 2026-03-06 |
| REVEAL - Research With I-124 EVuzamitide to Elucidate Cardiac AmyLoidosis I-124 evuzamitide - Cardiac Amyloidosis | Phase 3 | Completed | Sharmila Dorbala | 204 | 2025-01-14 | 2026-04-30 |
| Efficacy, Safety, Pharmacokinetics, Pharmacodynamics, and Immunogenicity of Eculizumab in Chinese Adults With gMG Eculizumab - Generalized Myasthenia Gravis (gMG), Refractory gMG | Phase 3 | Completed | Alexion Pharmaceuticals, Inc. | 15 | 2025-01-06 | 2026-01-15 |
| The Effect of High-thoracic Erector Spinae Plane Block on Postoperative Pain and Diaphragmatic Function in Posterior Cervical Spine Surgery Erector spina plane block (ESP), Bupivacain (preoperative) - Cervical Spine Surgery, Pain Management | Phase 3 | Completed | Benha University | 50 | 2025-01-01 | 2026-09-01 |
| Analgesic Effects of Intranasal Diclofenac Sodium, Ibuprofen, and Paracetamol in Pediatric Tonsillectomy Cases Intravenous paracetamol, Intranasal Paracetamol, Intranasal Diclofenac Sodium - Tonsil Disease, Pain Management | Phase 3 | Completed | Bezmialem Vakif University | 60 | 2024-12-15 | 2025-02-28 |
| A Clinical Trial of ACYW135 Group Meningococcal Polysaccharide Conjugate Vaccine (CRM197 Vector) in 7 to 17 Year Olds MCV4, MPSV4 - Meningococcal Meningitis | Phase 3 | Completed | CanSino Biologics Inc. | 840 | 2024-12-14 | 2026-08-06 |
| Melatonin fOr CHronic bAck Pain (The MOCHA Trial) Melatonin 10 MG, Placebo - Back Pain Lower Back Chronic, Insomnia | Phase 3 | Completed | Odense University Hospital | 220 | 2024-12-11 | 2026-04-22 |
| Double-blind, Randomized Trial of PRAX-628 in Adults With Focal Seizures to Evaluate Efficacy and Safety (POWER1) 20mg/day PRAX-628 for 6 weeks then 30mg/day PRAX-628 for remaining 6 weeks, Placebo - Focal Seizure | Phase 2 / Phase 3 | Completed | Praxis Precision Medicines | 255 | 2024-12-11 | 2026-08-10 |
| A Study to Evaluate the Efficacy and Safety of Daridorexant in Participants With Insomnia Disorder Daridorexant, Placebo - Insomnia Disorder | Phase 3 | Completed | Nxera Pharma Korea Co., Ltd. | 164 | 2024-12-04 | 2026-01-21 |
| Efficacy and Safety of Early Combined Therapy With PCSK9 Inhibitors and Statins in Acute Ischemic Stroke PCSK9 inhibitors combined with atorvastatin/rosuvastatin, Atorvastatin/Rosuvastatin - Acute Ischemic Stroke | Phase 2 / Phase 3 | Completed | Xiang Luo | 429 | 2024-11-29 | 2026-06-09 |
| A Study to Evaluate the Efficacy and Safety of HRG2010 in Parkinson's Disease With Motor Fluctuations HRG2010; Sustained-release Carbidopa/Levodopa administered placebo, Sustained-release Carbidopa/Levodopa; HRG2010 placebo - Parkinson's Disease | Phase 3 | Completed | Jiangsu HengRui Medicine Co., Ltd. | 165 | 2024-11-06 | 2026-06-08 |
| Oxyhydrogen Nanobubble Infusion as a Complementary Therapy in Patients With Parkinsonism oxyhydrogen nanobubble infusion - Parkinson Disease | Phase 2 / Phase 3 | Completed | dr. Siti Nurlaela, SpN | 35 | 2024-11-01 | 2026-03-12 |
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Stroke (220) · Parkinson Disease (209) · Alzheimer Disease (193) · Epilepsy (185) · Migraine Disorders (181) · Multiple Sclerosis (154) · Agnosia (132) · Pain (129) · Sleep Initiation and Maintenance Disorders (129) · Seizures (110) · Ischemic Stroke (103) · Poliomyelitis (89) · Dementia (80) · Fibromyalgia (80) · Brain Neoplasms (66)
Central Nervous System Diseases (1979) · Brain Diseases (1679) · Pathological Conditions, Signs and Symptoms (1333) · Signs and Symptoms (1090) · Neurologic Manifestations (1040) · Mental Disorders (643) · Neurodegenerative Diseases (605) · Neuromuscular Diseases (578) · Vascular Diseases (481) · Cardiovascular Diseases (475) · Cerebrovascular Disorders (405) · Pathologic Processes (398) · Neurobehavioral Manifestations (379) · Immune System Diseases (338)
Pregabalin (69) · Sodium Chloride (52) · Saline Solution (48) · Botulinum Toxins, Type A (44) · Topiramate (40) · Aspirin (36) · Levetiracetam (35) · Lacosamide (31) · Dexmedetomidine (30) · Radiotherapy (28) · Gabapentin (25) · Human Growth Hormone (25) · Pramipexole (25) · Meningococcal Vaccines (24) · nabiximols (24)
GlaxoSmithKline (86) · Pfizer (71) · Novartis Pharmaceuticals (68) · Pfizer's Upjohn has merged with Mylan to form Viatris Inc. (56) · UCB Pharma (56) · Johnson & Johnson Pharmaceutical Research & Development, L.L.C. (55) · Assistance Publique - Hôpitaux de Paris (54) · Sanofi Pasteur, a Sanofi Company (52) · Eli Lilly and Company (47) · Sanofi (41) · Jazz Pharmaceuticals (39) · Biogen (30) · Boehringer Ingelheim (28) · Eisai Inc. (28) · Merck Sharp & Dohme LLC (28)
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