76 completed, 10 terminated, 7 unknown, 4 recruiting. 37 Phase 3, 24 Phase 2, 14 Phase 1, 11 Phase 4, 4 Not applicable.
Follow Lacosamide: new trials by email Literature Review of Lacosamide trials Research Report on Lacosamide
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Evaluation of the Efficacy, Safety, and Tolerability of Lacosamide in Major Depressive Episodes of Bipolar Disorder Types I and II. Lacosamide, Placebo - Bipolar Affective Disorder | Phase 3 | Recruiting | University of Sao Paulo | 40 | 2026-01-09 | 2026-02-20 |
| Lacosamide Intravenous Injection for Emergency Termination of Status Epilepticus Lacosamide (LCM) - Epilepsy, Status Epilepticus | Not yet recruiting | Second Affiliated Hospital of Guangzhou Medical University | 100 | 2025-06-06 | 2025-05-30 | |
| Intravenous Lacosamide for the Treatment of Acute Pain in Trigeminal Neuralgia Lacosamide - Trigeminal Neuralgia | Recruiting | Hospital Universitari de Bellvitge | 20 | 2025-04-21 | 2026-09-15 | |
| Seizure Prevention in Traumatic Brain Injury With Levetiracetam and Lacosamide levetiracetam, lacosamide - Traumatic Brain Injury | Phase 4 | Recruiting | Wake Forest University Health Sciences | 600 | 2025-04-18 | 2026-04-24 |
| Comparative Efficacy of Pregabalin and Lacosamide in Patients With Herpes Zoster and Post Herpetic Neuralgia Pregabalin, Lacosamide - Herpes Zoster (HZ), Post Herpetic Neuralgia (PHN) | Not applicable | Recruiting | CMH Kharian Medical College | 50 | 2025-04-10 | 2025-05-14 |
| Lacosamide Versus Topiramate in Migraine Lacosamide 50 MG, Topiramate 50Mg Tab - Migraine Disorders | Phase 3 | Unknown | Kafrelsheikh University | 600 | 2024-02-01 | 2024-03-29 |
| Improvement Effect of Lacosamide and Levetiracetam on Cognitive in Alzheimer's Disease Patients With Epilepsy Lacosamide 100 mg, Levetiracetam 250mg - Alzheimer Disease 3, Epilepsy | Phase 4 | Unknown | Xiangya Hospital of Central South University | 140 | 2023-07-05 | 2023-08-04 |
| An Open Label, Balanced, Randomized, Two-Treatment, Two-Period, Two-Sequence, Two-way Crossover, Oralcomparative Pharmacokinetic（PK）Study of Lacosamide Extended-Release Tablets , Adult, Human Subjects Under Fasting Conditions. Lacosamide Tablets, Lacosamide extended release tablets - Epilepsy | Phase 1 | Unknown | Overseas Pharmaceuticals, Ltd. | 16 | 2023-04-01 | 2023-03-28 |
| STTEPP: Safety, Tolerability and Dose Limiting Toxicity of Lacosamide in Patients With Painful Chronic Pancreatitis Lacosamide - Chronic Pain, Chronic Pain Syndrome | Phase 1 | Active not recruiting | Indiana University | 21 | 2023-03-17 | 2026-06-03 |
| Combined Effect of Pregabalin and Oxycodone, and Lacosamide and Oxycodone, on Breathing Pregabalin 150mg, Oxycodone 10mg, Lacosamide 150 mg - Opioid-induced Respiratory Depression | Phase 4 | Completed | Leiden University Medical Center | 24 | 2022-10-10 | 2024-06-04 |
| Comparative Clinical Study Evaluating the Possible Efficacy of Duloxetine, Gabapentin and Lacosamide on Oxaliplatin-Induced Peripheral Neuropathy in Cancer Patients Duloxetine, Gabapentin, Lacosamide - Oncology | Phase 4 | Completed | Tanta University | 93 | 2022-09-01 | 2024-11-22 |
| Lacosamide Versus Propranolol in Migraine Lacosamide tablet, Propranolol - Migraine Disorders | Phase 3 | Completed | Kafrelsheikh University | 600 | 2022-06-01 | 2024-05-01 |
| The Lacosamide's Effect on Calcitonin Gene-related Peptide in Migraine Patients Lacosamide 50 MG Oral Tablet, Ibuprofen 400 mg - Effect of Drug, Migraine Disorders | Phase 3 | Completed | Kafrelsheikh University | 200 | 2022-06-01 | 2024-03-21 |
| Drug Concentrations in Breast Milk and Prediction of Blood Levels of the Breastfed Infants either of Atenolol, Bupropion, Brivaracetam, Escitalopram, Fluconazole, Lacosamide, Lamotrigine, Levetiracetam, Methotrexate or Ezetimibe - Breast Feeding | Completed | The Hospital for Sick Children | 39 | 2022-03-09 | 2024-04-10 | |
| Lacosamide in Neonatal Status Epilepticus Lacosamide, Phenobarbital - Epilepsy | Phase 3 | Unknown | Sherief Abd-Elsalam | 60 | 2022-03-01 | 2022-03-22 |
| Dual Anti-glutamate Therapy in Super-refractory Status Epilepticus After Cardiac Arrest Ketamine, Any anti-epileptic and anesthetic therapy, excluding Ketamine and Perampanel - Status Epilepticus, Cardiac Arrest | Completed | University of Milano Bicocca | 84 | 2022-01-15 | 2026-07-14 | |
| COMPARISON OF EFFICACY OF DIFFERENT DRUG COMBINATIONS IN ACUTE SCIATICA Lacosamide 50 MG Oral Tablet [Vimpat], Codeine Phosphate, Diclofenac Sodium - Sciatica Acute, Sciatica | Phase 3 | Completed | Pakistan Institute of Medical Sciences | 120 | 2021-09-28 | 2022-11-23 |
| A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Lacosamide in Neonates With Repeated Electroencephalographic Neonatal Seizures Lacosamide intravenous, Lacosamide oral, Active Comparator - Electroencephalographic Neonatal Seizures, Epilepsy | Phase 2 | Terminated | UCB Biopharma SRL | 29 | 2021-03-31 | 2025-10-03 |
| A Real World Study on the Efficacy and Safety of Lacosamide as Add-on Therapy for Focal-onset Epilepsy lacosamide - Epilepsy, Focal-Onset Seizure | Unknown | Jiangxi Qingfeng Pharmaceutical Co. Ltd. | 200 | 2021-01-31 | 2021-02-04 | |
| A Study to Test the Long-term Use of Oral Lacosamide in Pediatric Study Participants Who Completed NCT01964560 (EP0034) or NCT00938912 (SP848) and Received Lacosamide Treatment Lacosamide - Epilepsy | Phase 3 | Completed | UCB Biopharma SRL | 48 | 2020-12-28 | 2025-08-28 |
Showing 20 of 102. Sign in to see all of them.
Epilepsy (44) · Seizures (17) · Epilepsies, Partial (13) · Diabetic Neuropathies (7) · Epilepsy, Idiopathic Generalized (4) · Migraine Disorders (4) · Status Epilepticus (3) · Alcoholism (2) · Brain Injuries, Traumatic (2) · Glioma (2) · Neuralgia, Postherpetic (2) · Neuropathy, Painful (2) · Osteoarthritis (2) · Renal Insufficiency (2) · Acute Kidney Injury (1)
UCB Pharma (29) · UCB BIOSCIENCES, Inc. (12) · UCB Biopharma S.P.R.L. (5) · Kafrelsheikh University (3) · UCB BIOSCIENCES GmbH (3) · UCB Pharma SA (3) · Indiana University (2) · Le Bonheur Children's Hospital (2) · London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's (2) · UCB Biopharma SRL (2) · UCB Japan Co. Ltd. (2) · Aatif Husain (1) · Academisch Ziekenhuis Maastricht (1) · Assistance Publique - Hôpitaux de Paris (1) · Boston Medical Center (1)
United States (43) · Germany (24) · France (17) · Poland (17) · China (15) · Hungary (15) · Italy (14) · Spain (14) · Romania (13) · United Kingdom (13) · Mexico (12) · Australia (11) · Bulgaria (11) · Czechia (11) · Japan (11)
James W Wheless, MD (2) · Aatif Husain, MD (1) · Annick Desjardins, M.D. (1) · Aynur Unalp-Arida, MD, PhD (1) · Bryan M Sakamoto, M.D., PhD (1) · Catharina G Faber, MD, PhD (1) · Dong Zhou, Doctor (1) · Eric Devine, PhD (1) · Helge Frieling, Prof., MD (1)
PMID 18619874, PMID 11914403, PMID 12807523, PMID 17237664, PMID 17888078, PMID 28086164, PMID 34246118, PMID 34265173, PMID 39216464, PMID 8984084, PMID 10870744, PMID 11137386, PMID 11165371, PMID 11786502, PMID 14621285, PMID 14625037, PMID 15647484, PMID 15800228, PMID 15951714, PMID 16508405, PMID 16844492, PMID 17123731, PMID 17199030, PMID 17433624, PMID 17635557, PMID 17853395, PMID 17955107, PMID 18294378, PMID 18362258, PMID 18378801, PMID 18419722, PMID 18774343, PMID 19409861, PMID 19789074, PMID 20031953, PMID 20086062, PMID 21029787, PMID 21148579, PMID 21249671, PMID 21412914, PMID 21765969, PMID 22336864, PMID 22372628, PMID 22494121, PMID 22708895, PMID 22898544, PMID 23737404, PMID 23859801, PMID 23953988, PMID 24275520
2014 (7), 2004 (3), 2005 (1), 2009 (1), 2015 (1), 2016 (1), 2018 (1), P30CA016672 (1), R01DK132709 (1), R21AA026389 (1)