10 completed, 5 unknown, 2 recruiting, 1 active not recruiting. 19 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 19 | Completed 10, Unknown 5, Recruiting 2, Active not recruiting 1, Terminated 1 |
Follow Muscle Weakness: new trials by email Literature Review of Muscle Weakness trials Research Report on Muscle Weakness
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Low-Volume Pericapsular Nerve Group (PENG) Block With Dexamethasone vs Standard-Volume PENG Block After Total Hip Arthroplasty Pericapsular nerve group (PENG) block, Bupivacaine, Dexamethasone - Pain, Postoperative, Muscle Weakness | Phase 4 | Recruiting | Ain Shams University | 60 | 2026-10-15 | 2026-10-16 |
| The Effect of Methylprednisolone on the Reversal Time of Rocuronium by Sugammadex in the Pediatric Patient Group methylprednisolone, Saline (NaCl 0,9 %) (placebo) - Sugammadex Reversal Time, Muscle Weakness | Phase 4 | Completed | Konya City Hospital | 80 | 2024-10-01 | 2025-01-30 |
| TESTO-TRIAL: Use of Testosterone in Critically Ill Patients Testosterone cypionate (200mg/3ml), Sesame oil (3ml) - Weaning Failure, Muscle Weakness | Phase 4 | Active not recruiting | Leticia Maria Defendi Barboza Marson | 94 | 2024-09-09 | 2024-12-18 |
| Depo-Medrol on Psoas After LLIF Depo-Medrol, Gel-Flow NT - Muscle Weakness, Pain, Postoperative | Phase 4 | Recruiting | Hardeep Singh | 80 | 2023-05-12 | 2025-07-24 |
| CORTERAS STUDY: The Effect of Corticosteroids on Early Recovery After Major Surgery in Elderly Patients Methylprednisolone, NaCl 0.9% - Inflammatory Response, Weakness, Muscle | Phase 4 | Completed | Ziekenhuis Oost-Limburg | 751 | 2022-02-16 | 2026-01-27 |
| Transmucular Quadratus Lumborum Block: Potential Quadriceps Muscle Weakness Ropivacaine, Quadriceps muscle strength, Timed Up and Go - Neuromuscular Blockade | Phase 4 | Completed | Zealand University Hospital | 20 | 2021-10-02 | 2021-12-21 |
| Evaluation of Effectiveness of Combining High Protein Intake With Early Physical Exercise During Critical Illness Amino Acid, Physical exercise - Muscle Weakness | Phase 4 | Completed | Tanta University | 70 | 2021-07-01 | 2023-05-26 |
| Reversal of Moderate or Superficial Neuromuscular Blockade Induced by Cisatracurium Reversal of moderate neuromuscular blockade, Reversal of superficial neuromuscular blockade, Two-step reversal - Neostigmine, Neuromuscular Blocking Agents | Phase 4 | Completed | Pontificia Universidade Catolica de Sao Paulo | 60 | 2021-06-01 | 2022-05-19 |
| General Anesthesia With and Without Muscle Relaxation and Muscle Strength Recovery Rocuronium, General anesthesia for surgery - Rocuronium, Muscle Weakness | Phase 4 | Completed | Clinical Hospital Centre Zagreb | 60 | 2020-04-01 | 2026-01-21 |
| 7T Magnetic Resonance Spectroscopy and Skeletal Muscle Biopsy Findings in Statin Associated Adverse Muscle Events Simvastatin 40mg - Muscle Cramp, Ache | Phase 4 | Terminated | University of Texas Southwestern Medical Center | 3 | 2018-08-17 | 2023-02-14 |
| Best Practice Using Rocuronium and Reversal With Neostigmine or Sugammadex Protocol for rocuronium neuromuscular block - Muscle Weakness | Phase 4 | Completed | University of Washington | 201 | 2018-05-21 | 2022-11-09 |
| Effects of Supplementation of Vitamin D in Patients With Crohn's Disease Vitamin D, Placebo - Crohn Disease, Vitamin D Deficiency | Phase 4 | Unknown | Federal University of Juiz de Fora | 110 | 2016-12-01 | 2018-06-29 |
| Neuromuscular Blockade for Optimising Surgical Conditions During Spinal Surgery Rocuronium 0.9 mg/kg, Rocuronium 0.6 mg/kg - Neuromuscular Block, Orthopedic Disorder of Spine | Phase 4 | Unknown | The Catholic University of Korea | 60 | 2016-09-01 | 2019-04-01 |
| Magnesium in Liver Cirrhosis magnesium, Placebo - LIVER CIRRHOSIS | Phase 4 | Unknown | Meir Medical Center | 50 | 2013-08-01 | 2013-07-12 |
| Innovative Training Program for Elderly in Need of Care Individuals SR-WBV, Virtual Games (VG), Aktiv Tramp (Swiss Frei AG, Switzerland) - Poor Performance Status, Muscle Weakness | Phase 4 | Completed | Bern University of Applied Sciences | 30 | 2013-01-01 | 2016-07-15 |
| Muscular Electrostimulation of the Sedated and Mechanically Ventilated Critically Ill Patient. Analysis of the Effect on Acquired Muscular Weakness and Its Clinical Consequences. Muscular electrostimulation and percutaneus muscular biopsy. - Polyneuropathy | Phase 4 | Unknown | Hospital Universitario La Fe | 40 | 2012-10-01 | 2014-01-10 |
| Coenzyme Q10 in Older Athletes Treated With Statin Medications Coenzyme q 10, placebo - Muscle Weakness, Myalgia | Phase 4 | Completed | Richard Deichmann, MD | 20 | 2009-11-01 | 2012-05-03 |
| Evaluation of the Effects of L-Carnitine Injection in Patients Undergoing Hemodialysis L-Carnitine Injection - Cardiac Complications, Signs and Symptoms | Phase 4 | Unknown | National Taiwan University Hospital | 40 | 2004-10-01 | 2006-03-01 |
| Physiologic Effects of PRMS & Testosterone in the Debilitated Elderly exercise, testosterone - Muscle Weakness, Muscular Atrophy | Phase 4 | Completed | US Department of Veterans Affairs | 88 | 1999-01-01 | 2011-06-23 |
Myalgia (2) · Pain, Postoperative (2) · Anemia (1) · Bone Diseases, Metabolic (1) · Critical Illness (1) · Crohn Disease (1) · Fatigue (1) · Hypotension (1) · Liver Cirrhosis (1) · Mobility Limitation (1) · Muscle Cramp (1) · Muscular Atrophy (1) · Pain (1) · Paresthesia (1)
Muscular Diseases (19) · Musculoskeletal Diseases (19) · Nervous System Diseases (19) · Neurologic Manifestations (19) · Neuromuscular Manifestations (19) · Pathologic Processes (19) · Pathological Conditions, Signs and Symptoms (19) · Signs and Symptoms (18) · Neuromuscular Diseases (3) · Pain (3) · Atrophy (2) · Digestive System Diseases (2) · Musculoskeletal Pain (2) · Pathological Conditions, Anatomical (2) · Postoperative Complications (2)
Exercise (2) · Methylprednisolone (2) · Rocuronium (2) · Sodium Chloride (2) · Amino Acids (1) · Anesthesia, General (1) · Blood Specimen Collection (1) · Bupivacaine (1) · Calcium Dobesilate (1) · Carnitine (1) · Clinical Protocols (1) · Dental Occlusion (1) · Dexamethasone (1) · Magnesium (1) · Magnesium Oxide (1)
Ain Shams University (1) · Bern University of Applied Sciences (1) · Clinical Hospital Centre Zagreb (1) · Federal University of Juiz de Fora (1) · Hardeep Singh (1) · Hospital Universitario La Fe (1) · Konya City Hospital (1) · Leticia Maria Defendi Barboza Marson (1) · Meir Medical Center (1) · National Taiwan University Hospital (1) · Pontificia Universidade Catolica de Sao Paulo (1) · Richard Deichmann, MD (1) · Tanta University (1) · The Catholic University of Korea (1) · US Department of Veterans Affairs (1)
United States (5) · Brazil (3) · Egypt (2) · Belgium (1) · Croatia (1) · Denmark (1) · Israel (1) · South Korea (1) · Spain (1) · Switzerland (1) · Taiwan (1) · Turkey (Türkiye) (1)
Azza A AbdelAleem, MD (1) · Dennis Sullivan, MD (1) · Dietmar Schmidtbleicher, Prof (1) · Eduardo T Moro, MD (1) · Eling Douwe de Bruin, PhD (1) · Hardeep Singh, M.D. (1) · Heiner Baur, PhD (1) · Jin Young Chon, M.D., Ph.D. (1) · Katrine Tanggaard, MD (1) · Kwan-Dun Wu, Ph.D (1) · Lorenz Radlinger, PhD (1) · Mohamed F Morsi, M.B., B.Ch., M.Sc. (1) · Richard Deichmann, MD (1) · Rob de Bie, Prof. (1)
PMID 16260965, PMID 27239241, PMID 37205804, PMID 38754991, PMID 40673736