817 completed, 297 unknown, 219 recruiting, 128 not yet recruiting. 944 Not applicable, 86 Phase 2, 42 Phase 3, 35 Phase 1, 29 Phase 4.
Follow this condition Literature Review of Muscular Atrophy trials Research Report on Muscular Atrophy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Mixed Exercise Training and Novel Multi-Nutrient Supplementation in Young Adults Multi-nutrient supplement, Exercise - Sarcopenia | Not applicable | Withdrawn | McMaster University | 2030-01-20 | 2024-01-30 | |
| The FORCE Trial Pilot: Fish Oil-enriched Nutrition for Radiotherapy in Cancer of the hEad and Neck Nutrition counseling, Fresubin Supportan - Head &Amp;Amp; Neck Squamous Cell Carcinoma | Phase 1 / Phase 2 | Not yet recruiting | Anna Arthur, PhD | 15 | 2027-06-01 | 2026-08-07 |
| Evaluate the Efficacy and Safety of EN001 in Patients With Sarcopenia EN001, EN001 Placebo - Sarcopenia | Phase 1 / Phase 2 | Not yet recruiting | ENCell | 132 | 2027-03-01 | 2026-09-11 |
| Effect of Protein, Mobility Therapy and Electric Stimulation on Recovery in Older ICU Survivors MRP and High Protein Supplement (HPRO) and Neuromuscular Electric Stimulation (NMES) - Critical Illness, Sarcopenia | Early Phase 1 | Not yet recruiting | University of Maryland, Baltimore | 78 | 2027-03-01 | 2026-05-06 |
| The Simplified Total-body Resistance Exercise for Muscular Hypertrophy for Diabetic Population (D-STORM) D-STORM Resistance Training Programme, usual care - Type 2 Diabetes Mellitus (T2DM), Sarcopenia | Not applicable | Not yet recruiting | Universiti Teknologi Mara | 56 | 2027-01-01 | 2026-06-25 |
| Routine Validation and Reproducibility Testing of Laboratory Assays and Research Techniques Used for Endocrine, Cardiometabolic, and Musculoskeletal Disorder Research (VALD) Endothelial cell collection - Obesity and Obesity-related Medical Conditions, Diabetes | Recruiting | Bettina Mittendorfer | 100 | 2027-01-01 | 2026-05-07 | |
| Yijinjing Exercise for Musculoskeletal Health in Adults With Sarcopenia Modified Yijinjing Exercise, Progressive Resistance Training, Dietary Counseling and Health Education - Sarcopenia | Not applicable | Not yet recruiting | Beijing Hospital of Traditional Chinese Medicine | 240 | 2027-01-01 | 2026-10-21 |
| Exercise and Nutritional Intervention in Patients With Melanoma Receiving Immunotherapy Structured Resistance Exercise, Individualized Nutritional Support - Melanoma | Not applicable | Not yet recruiting | Institute of Oncology Ljubljana | 40 | 2026-12-01 | 2026-10-07 |
| Feasibility of a Novel Resistance Exercise in Individuals With Osteoporosis Exercise training - Osteopenia, Osteoporosis | Not applicable | Withdrawn | University of Alabama at Birmingham | 2026-12-01 | 2026-07-01 | |
| HMB Plus Vitamin D to Preserve Muscle in Older Adults Starting Semaglutide Calcium-HMB Plus Vitamin D3, Matching placebo - Type 2 Diabetes Mellitus (T2DM), Sarcopenia | Phase 2 | Not yet recruiting | Vanderbilt University Medical Center | 90 | 2026-12-01 | 2026-08-28 |
| Targeted Nutritional Intervention (HMB, Arginine, Glutamine) in Patients With Pancreatic Cancer HMB / L-Arginine / L-Glutamine oral nutritional mixture, Standard Dietary Counseling - PDAC, Pancreas Adenocarcinoma (MSI-H) | Not applicable | Not yet recruiting | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | 24 | 2026-12-01 | 2026-10-20 |
| Comparison of Sarcopenia Index, Diaphragm Ultrasonography, and Traditional Weaning Parameters in Predicting Successful Weaning From Mechanical Ventilation sarcopenia index, diaphragma ultrasound, parameters of mechanical ventilation (MV) - Ventilator Weaning, Sarcopenia | Not yet recruiting | Kocaeli City Hospital | 80 | 2026-11-15 | 2026-09-28 | |
| Vicia Faba Peptides and Resistance Training in the Elderly Vicia faba L.-derived peptides, Placebo, Supervised Resistance Training - Healthy Aging | Not applicable | Enrolling by invitation | Universidade Cesumar (UNICESUMAR) | 77 | 2026-11-01 | 2026-10-07 |
| Effectiveness of Combined GLP-1/GIP Dual Agonist Therapy and Structured Exercise on Skeletal Muscle Morphology, Quality, and Physical Function in Overweight and Obese Individuals Resistance exercise, Lifestyle recommendations - Obesity, Sarcopenia | Not applicable | Not yet recruiting | Acibadem University | 108 | 2026-11-01 | 2026-06-04 |
| Sarcopenia Screening in Advanced Coxarthrosis: The SARCO-COX Study Intensive Physical Rehabilitation, Preoperative Sarcopenia Screening - Sarcopenia, Coxarthrosis | Not applicable | Not yet recruiting | Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y Salud | 150 | 2026-11-01 | 2026-09-15 |
| Women in Action: A Multicomponent Intervention for Older Women Multicomponent exercise, nutrition, and psychoeducational program - Sarcopenia, Physical Inactivity | Not applicable | Not yet recruiting | Universidad de Oviedo | 214 | 2026-11-01 | 2026-10-06 |
| Personalised Nutritional Care in Older Patients With Pancreatic Ductal Adenocarcinoma Experimental: Personalised nutritional care delivered by a trained dietitian - Pancreatic Cancer | Not applicable | Not yet recruiting | Inna Chen, MD | 250 | 2026-11-01 | 2026-09-16 |
| Automated and Reliable Estimation of Patient Height From CT Scan Using an Artificial Intelligence Algorithm Patient With an Appointment for an Abdominal CT Scan and Able to Stand up for Height Measurement | Not yet recruiting | University Hospital, Grenoble | 200 | 2026-11-01 | 2026-10-15 | |
| Preoperative Muscle Stiffness, Functional Reserve, and Postoperative Quality of Recovery in Lower Extremity Arthroplasty Handgrip Strength (HGS) Measurement, Ultrasound Shear Wave Elastography (SWE) - Osteoarthritis (Knee / Hip), Sarcopenia | Not yet recruiting | Ankara Etlik City Hospital | 80 | 2026-11-01 | 2026-10-16 | |
| Exercise Intervention for Breast Cancer Patients With Sarcopenia "Exercise for Muscle Health" Program - Sarcopenia, Breast Cancer | Not applicable | Not yet recruiting | Capital Medical University | 104 | 2026-10-30 | 2026-10-19 |
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Sarcopenia (1289) · Frailty (164) · Motor Activity (159) · Obesity (90) · Malnutrition (87) · Osteoporosis (65) · Muscle Weakness (64) · Neoplasms (55) · Critical Illness (46) · Cachexia (37) · Bone Diseases, Metabolic (31) · Stroke (30) · Renal Insufficiency, Chronic (29) · Inflammation (28)
Pathological Conditions, Signs and Symptoms (1633) · Pathological Conditions, Anatomical (1632) · Signs and Symptoms (1632) · Nervous System Diseases (1631) · Neurologic Manifestations (1631) · Neuromuscular Manifestations (1629) · Atrophy (1613) · Pathologic Processes (419) · Nutritional and Metabolic Diseases (346) · Musculoskeletal Diseases (229) · Behavior (203) · Nutrition Disorders (198) · Metabolic Diseases (173) · Body Weight (143)
Exercise (90) · Resistance Training (82) · Dietary Supplements (17) · Whey Proteins (16) · Proteins (15) · Absorptiometry, Photon (14) · Nutritional Status (14) · maltodextrin (14) · Creatine (12) · Leucine (12) · Control Groups (11) · Hand Strength (11) · Standard of Care (11) · Cholecalciferol (10) · Vitamin D (10)
National Taiwan University Hospital (25) · Maastricht University Medical Center (22) · University of Nottingham (22) · McMaster University (16) · Chang Gung Memorial Hospital (14) · University Hospital, Clermont-Ferrand (13) · Bispebjerg Hospital (12) · Novartis Pharmaceuticals (12) · Tufts University (12) · University of Erlangen-Nürnberg Medical School (12) · The University of Texas Medical Branch, Galveston (11) · University of Saskatchewan (10) · VA Office of Research and Development (10) · Istanbul Physical Medicine Rehabilitation Training and Research Hospital (9) · Ankara City Hospital Bilkent (8)
United States (289) · Turkey (Türkiye) (137) · United Kingdom (112) · Taiwan (110) · Spain (106) · France (95) · China (82) · Italy (78) · Canada (64) · Denmark (52) · Brazil (49) · Netherlands (49) · Belgium (46) · Germany (42) · South Korea (40)
Luc JC van Loon, PhD (7) · Stuart M Phillips, PhD (7) · Bess Dawson-Hughes, MD (5) · Galip Can Uyar, MD (5) · Sang Yeoup Lee, MD, PhD (5) · Charlotte Suetta, Professor (4) · Elena Volpi, MD, PhD (4) · Luc van Loon, PhD (4) · Paul Coen, PhD (4) · Bettina Mittendorfer, PhD (3) · J. Peter Rubin, MD (3) · Klaus Engelke, PhD (3)
PMID 30312372, PMID 20392703, PMID 32069356, PMID 24737557, PMID 32033882, PMID 28095426, PMID 31081853, PMID 32941253, PMID 12028177, PMID 12472328, PMID 16030064, PMID 16614412, PMID 16896165, PMID 17351147, PMID 17912368, PMID 18323467, PMID 18342407, PMID 18511703, PMID 18713956, PMID 18787087, PMID 20876843, PMID 21093718, PMID 21448087, PMID 22018588, PMID 22338078, PMID 24374288, PMID 24737560, PMID 25243821, PMID 25475435, PMID 26882087, PMID 26922142, PMID 27077744, PMID 27138015, PMID 27507236, PMID 27935521, PMID 28473464, PMID 29349935, PMID 30513782, PMID 30587866, PMID 31171417, PMID 31547952, PMID 31722892, PMID 32230954, PMID 32469388, PMID 33249320, PMID 34121127, PMID 34708217, PMID 36070134, PMID 36905161, PMID 37752426
P30AG028740 (5), 2018 (4), 2015 (2), 2017 (2), 2023 (2), P30AG028747 (2), 1IK2RD000462 (1), 2016 (1), 2019 (1), 2025 (1), F31AT005384 (1), IK2RD000484-01A1 (1), IK2RX003245-03 (1), K01HL148503 (1), K23DK099442 (1)